Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C712
  Reference Plasmid   NZ_CP050488.1
  Reference Plasmid Size   75933
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0173133 KIMGEEEB_00051 43411 3 Gut 0.38 protein_coding synonymous_variant LOW 801T>C Ile267Ile
M0173134 KIMGEEEB_00051 43477 3 Gut 0.38 protein_coding synonymous_variant LOW 735T>A Val245Val
M0173135 KIMGEEEB_00051 43607 3 Gut 0.38 protein_coding missense_variant MODERATE 605T>G Leu202Arg
M0173136 KIMGEEEB_00051 43924 3 Gut 0.38 protein_coding synonymous_variant LOW 288T>C Gly96Gly
M0173137 KIMGEEEB_00051 43941 3 Gut 0.38 protein_coding missense_variant MODERATE 271A>G Lys91Glu
M0173138 KIMGEEEB_00051 43956 3 Gut 0.38 protein_coding synonymous_variant LOW 256T>C Leu86Leu
M0173139 KIMGEEEB_00051 43958 3 Gut 0.38 protein_coding missense_variant MODERATE 254C>T Thr85Met
M0173140 KIMGEEEB_00051 43975 3 Gut 0.38 protein_coding synonymous_variant LOW 237G>A Gln79Gln
M0173141 KIMGEEEB_00051 43996 3 Gut 0.38 protein_coding synonymous_variant LOW 216T>G Leu72Leu
M0173142 KIMGEEEB_00051 43998 3 Gut 0.38 protein_coding missense_variant MODERATE 214C>T Leu72Phe
M0173143 KIMGEEEB_00051 44099 3 Gut 0.38 protein_coding missense_variant MODERATE 113A>T Tyr38Phe
M0173144 KIMGEEEB_00051 44184 3 Gut 0.38 protein_coding missense_variant MODERATE 28A>G Lys10Glu
M0173145 KIMGEEEB_00053 44885 3 Gut 0.38 protein_coding synonymous_variant LOW 36A>C Thr12Thr
M0173146 KIMGEEEB_00054 45414 3 Gut 0.38 protein_coding synonymous_variant LOW 1035A>G Glu345Glu
M0173147 KIMGEEEB_00054 45516 3 Gut 0.38 protein_coding synonymous_variant LOW 933C>T Ser311Ser
M0173148 KIMGEEEB_00054 45546 3 Gut 0.38 protein_coding synonymous_variant LOW 903A>G Gln301Gln
M0173149 KIMGEEEB_00054 45899 3 Gut 0.38 protein_coding synonymous_variant LOW 550C>A Arg184Arg
M0173150 KIMGEEEB_00054 46050 3 Gut 0.38 protein_coding synonymous_variant LOW 399G>A Glu133Glu
M0173151 KIMGEEEB_00054 46208 3 Gut 0.38 protein_coding missense_variant MODERATE 241A>G Ile81Val
M0173152 KIMGEEEB_00049 38550 3 Gut 0.38 protein_coding missense_variant MODERATE 2152A>G Thr718Ala
M0173153 KIMGEEEB_00049 38645 3 Gut 0.38 protein_coding missense_variant MODERATE 2057A>T Glu686Val
M0173154 KIMGEEEB_00049 38728 3 Gut 0.38 protein_coding synonymous_variant LOW 1974C>T Cys658Cys
M0173155 KIMGEEEB_00049 38862 3 Gut 0.38 protein_coding missense_variant MODERATE 1840C>A Gln614Lys
M0173156 KIMGEEEB_00049 38968 3 Gut 0.38 protein_coding synonymous_variant LOW 1734A>G Thr578Thr
M0173157 KIMGEEEB_00049 39033 3 Gut 0.38 protein_coding synonymous_variant LOW 1669T>C Leu557Leu
M0173158 KIMGEEEB_00049 39052 3 Gut 0.38 protein_coding synonymous_variant LOW 1650T>C Val550Val
M0173159 KIMGEEEB_00049 39181 3 Gut 0.38 protein_coding synonymous_variant LOW 1521C>A Val507Val
M0173160 KIMGEEEB_00049 39385 3 Gut 0.38 protein_coding synonymous_variant LOW 1317G>A Gly439Gly
M0173161 KIMGEEEB_00049 39648 3 Gut 0.38 protein_coding missense_variant MODERATE 1054A>C Ser352Arg
M0173162 KIMGEEEB_00049 40057 3 Gut 0.38 protein_coding synonymous_variant LOW 645G>A Gln215Gln
M0173163 KIMGEEEB_00045 40746 3 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -4775T>C None
M0173164 KIMGEEEB_00050 40767 3 Gut 0.38 protein_coding synonymous_variant LOW 399A>G Leu133Leu
M0173165 KIMGEEEB_00050 40821 3 Gut 0.38 protein_coding synonymous_variant LOW 345G>A Thr115Thr
M0173166 KIMGEEEB_00050 40830 3 Gut 0.38 protein_coding synonymous_variant LOW 336T>A Ala112Ala
M0173167 KIMGEEEB_00050 40832 3 Gut 0.38 protein_coding missense_variant MODERATE 334G>T Ala112Ser
M0173168 KIMGEEEB_00050 40839 3 Gut 0.38 protein_coding synonymous_variant LOW 327C>A Ser109Ser
M0173169 KIMGEEEB_00051 41278 3 Gut 0.38 protein_coding synonymous_variant LOW 2934T>G Thr978Thr
M0173170 KIMGEEEB_00051 41290 3 Gut 0.38 protein_coding synonymous_variant LOW 2922T>C Val974Val
M0173171 KIMGEEEB_00051 41461 3 Gut 0.38 protein_coding synonymous_variant LOW 2751T>C His917His
M0173172 KIMGEEEB_00051 41578 3 Gut 0.38 protein_coding synonymous_variant LOW 2634A>G Lys878Lys
M0173173 KIMGEEEB_00051 41713 3 Gut 0.38 protein_coding synonymous_variant LOW 2499A>G Leu833Leu
M0173174 KIMGEEEB_00051 41746 3 Gut 0.38 protein_coding synonymous_variant LOW 2466C>T Gly822Gly
M0173175 KIMGEEEB_00051 41764 3 Gut 0.38 protein_coding synonymous_variant LOW 2448C>T Ser816Ser
M0173176 KIMGEEEB_00051 41830 3 Gut 0.38 protein_coding synonymous_variant LOW 2382G>A Glu794Glu
M0173177 KIMGEEEB_00051 41971 3 Gut 0.38 protein_coding synonymous_variant LOW 2241T>C Gly747Gly
M0173178 KIMGEEEB_00051 41980 3 Gut 0.38 protein_coding synonymous_variant LOW 2232T>C Asn744Asn
M0173179 KIMGEEEB_00051 42174 3 Gut 0.38 protein_coding missense_variant MODERATE 2038A>C Met680Leu
M0173180 KIMGEEEB_00051 42190 3 Gut 0.38 protein_coding synonymous_variant LOW 2022A>G Thr674Thr
M0173181 KIMGEEEB_00051 42535 3 Gut 0.38 protein_coding synonymous_variant LOW 1677T>C Phe559Phe






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
KIMGEEEB_00065 PHI:8586 mntH1 78.2 2.4e-220 1 501 0.9728 0.9417 moths nosocomial infection divalent metal cation transporter unaffected pathogenicity






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term