Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C723
  Reference Plasmid   NZ_CP051730.1
  Reference Plasmid Size   6758
  Reference Plasmid GC Content   0.51
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0173556 BMPNHBLP_00001 4633 4 Gut 0.80 protein_coding upstream_gene_variant MODIFIER -4367G>A None
M0173557 BMPNHBLP_00004 4711 5 Gut 1.00 protein_coding missense_variant MODERATE 67T>A Cys23Ser
M0173558 BMPNHBLP_00004 4746 4 Gut 0.80 protein_coding synonymous_variant LOW 102G>T Val34Val
M0173559 BMPNHBLP_00005 5252 4 Gut 0.80 protein_coding synonymous_variant LOW 813C>T Ala271Ala
M0173560 BMPNHBLP_00005 5573 4 Gut 0.80 protein_coding synonymous_variant LOW 492T>C Arg164Arg
M0173561 BMPNHBLP_00005 5577 4 Gut 0.80 protein_coding missense_variant MODERATE 488A>C Glu163Ala
M0173562 BMPNHBLP_00002 6257 4 Gut 0.80 protein_coding upstream_gene_variant MODIFIER -4243C>T None
M0173563 BMPNHBLP_00002 6285 4 Gut 0.80 protein_coding upstream_gene_variant MODIFIER -4271G>T None
M0173564 BMPNHBLP_00002 6286 4 Gut 0.80 protein_coding upstream_gene_variant MODIFIER -4272C>T None
M0173565 BMPNHBLP_00002 6375 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -4361C>T None
M0173566 BMPNHBLP_00002 6495 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -4481A>G None
M0173567 BMPNHBLP_00002 6511 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -4497T>C None
M0173568 BMPNHBLP_00002 6538 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -4524A>G None
M0173569 BMPNHBLP_00006 6582 3 Gut 0.60 protein_coding missense_variant MODERATE 121G>C Val41Leu
M0173570 BMPNHBLP_00006 6591 3 Gut 0.60 protein_coding missense_variant MODERATE 112A>T Thr38Ser
M0173571 BMPNHBLP_00006 6592 3 Gut 0.60 protein_coding synonymous_variant LOW 111A>C Ser37Ser
M0173572 BMPNHBLP_00006 6601 3 Gut 0.60 protein_coding synonymous_variant LOW 102T>C Ser34Ser
M0173573 BMPNHBLP_00006 6607 3 Gut 0.60 protein_coding synonymous_variant LOW 96C>T Thr32Thr
M0173574 BMPNHBLP_00006 6625 3 Gut 0.60 protein_coding synonymous_variant LOW 78G>C Arg26Arg
M0173575 BMPNHBLP_00006 6626 3 Gut 0.60 protein_coding missense_variant MODERATE 77G>A Arg26Gln
M0173576 BMPNHBLP_00006 6651 3 Gut 0.60 protein_coding missense_variant MODERATE 52T>G Ser18Ala
M0173577 BMPNHBLP_00006 6652 3 Gut 0.60 protein_coding synonymous_variant LOW 51G>T Leu17Leu
M0173578 BMPNHBLP_00006 6662 3 Gut 0.60 protein_coding missense_variant MODERATE 41T>C Val14Ala
M0173579 BMPNHBLP_00002 980 3 Gut 0.60 protein_coding synonymous_variant LOW 1035C>T Ala345Ala
M0173580 BMPNHBLP_00002 1139 3 Gut 0.60 protein_coding synonymous_variant LOW 876T>C Ser292Ser
M0173581 BMPNHBLP_00002 1223 3 Gut 0.60 protein_coding synonymous_variant LOW 792T>G Gly264Gly
M0173582 BMPNHBLP_00002 1597 3 Gut 0.60 protein_coding synonymous_variant LOW 418C>T Leu140Leu
M0173583 BMPNHBLP_00002 1721 3 Gut 0.60 protein_coding synonymous_variant LOW 294T>A Pro98Pro
M0173584 BMPNHBLP_00002 1901 3 Gut 0.60 protein_coding synonymous_variant LOW 114A>G Gly38Gly
M0173585 BMPNHBLP_00002 1907 3 Gut 0.60 protein_coding synonymous_variant LOW 108C>T Gly36Gly
M0173586 BMPNHBLP_00001 2020 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -1754A>G None
M0173587 BMPNHBLP_00001 2129 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -1863G>A None
M0173588 BMPNHBLP_00001 2245 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -1979G>A None
M0173589 BMPNHBLP_00003 2586 3 Gut 0.60 protein_coding synonymous_variant LOW 1881C>A Arg627Arg
M0173590 BMPNHBLP_00003 2718 3 Gut 0.60 protein_coding missense_variant MODERATE 1749G>C Gln583His
M0173591 BMPNHBLP_00003 2922 3 Gut 0.60 protein_coding synonymous_variant LOW 1545C>T Arg515Arg
M0173592 BMPNHBLP_00003 3047 3 Gut 0.60 protein_coding synonymous_variant LOW 1420T>C Leu474Leu
M0173593 BMPNHBLP_00003 3632 3 Gut 0.60 protein_coding synonymous_variant LOW 835T>C Leu279Leu
M0173594 BMPNHBLP_00003 3725 3 Gut 0.60 protein_coding missense_variant MODERATE 742A>G Thr248Ala
M0173595 BMPNHBLP_00003 4197 3 Gut 0.60 protein_coding synonymous_variant LOW 270C>T Leu90Leu
M0173596 BMPNHBLP_00001 4546 4 Gut 0.80 protein_coding upstream_gene_variant MODIFIER -4280T>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
BMPNHBLP_00002 1.C.1.4.1 99.5 0 1 581 1.0000 0.9983 1 Channels/Pores 1.C Pore-Forming Toxins (Proteins and Peptides) 1.C.1 The Channel-forming Colicin (Colicin) Family
BMPNHBLP_00006 1.A.73.1.3 89.4 5e-16 1 47 1.0000 1.0000 1 Channels/Pores 1.A α-Type Channels 1.A.73 The Colicin Lysis Protein (CLP) Family