Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C724
  Reference Plasmid   NZ_CP051739.1
  Reference Plasmid Size   172627
  Reference Plasmid GC Content   0.50
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0173597 FDPBPMHP_00113 94466 3 Gut 0.25 protein_coding synonymous_variant LOW 345G>A Glu115Glu
M0173598 FDPBPMHP_00113 94470 3 Gut 0.25 protein_coding missense_variant MODERATE 341A>G Glu114Gly
M0173599 FDPBPMHP_00113 94489 3 Gut 0.25 protein_coding missense_variant MODERATE 322C>A Leu108Ile
M0173600 FDPBPMHP_00113 94493 3 Gut 0.25 protein_coding synonymous_variant LOW 318C>A Gly106Gly
M0173601 FDPBPMHP_00113 94496 3 Gut 0.25 protein_coding synonymous_variant LOW 315T>C Arg105Arg
M0173602 FDPBPMHP_00113 94505 3 Gut 0.25 protein_coding synonymous_variant LOW 306A>G Arg102Arg
M0173603 FDPBPMHP_00113 94506 3 Gut 0.25 protein_coding missense_variant MODERATE 305G>T Arg102Leu
M0173604 FDPBPMHP_00113 94507 3 Gut 0.25 protein_coding stop_gained HIGH 304C>T Arg102*
M0173605 FDPBPMHP_00113 94541 3 Gut 0.25 protein_coding synonymous_variant LOW 270T>C Tyr90Tyr
M0173606 FDPBPMHP_00113 94556 3 Gut 0.25 protein_coding synonymous_variant LOW 255A>G Thr85Thr
M0173607 FDPBPMHP_00113 94564 3 Gut 0.25 protein_coding missense_variant MODERATE 247A>G Ser83Gly
M0173608 FDPBPMHP_00113 94588 3 Gut 0.25 protein_coding missense_variant MODERATE 223A>G Ile75Val
M0173609 FDPBPMHP_00113 94628 3 Gut 0.25 protein_coding synonymous_variant LOW 183A>G Val61Val
M0173610 FDPBPMHP_00113 94640 3 Gut 0.25 protein_coding missense_variant MODERATE 171A>C Lys57Asn
M0173611 FDPBPMHP_00113 94646 3 Gut 0.25 protein_coding synonymous_variant LOW 165G>A Gly55Gly
M0173612 FDPBPMHP_00113 94703 3 Gut 0.25 protein_coding synonymous_variant LOW 108A>C Thr36Thr
M0173613 FDPBPMHP_00113 94745 3 Gut 0.25 protein_coding synonymous_variant LOW 66T>C Gly22Gly
M0173614 FDPBPMHP_00113 94768 3 Gut 0.25 protein_coding missense_variant MODERATE 43G>A Val15Ile
M0173615 FDPBPMHP_00114 94881 3 Gut 0.25 protein_coding missense_variant MODERATE 100G>A Val34Ile
M0173616 FDPBPMHP_00114 94886 3 Gut 0.25 protein_coding missense_variant MODERATE 95T>C Val32Ala
M0173617 FDPBPMHP_00114 94914 3 Gut 0.25 protein_coding missense_variant MODERATE 67G>A Gly23Ser
M0173618 FDPBPMHP_00114 94934 3 Gut 0.25 protein_coding missense_variant MODERATE 47G>A Arg16His
M0173619 FDPBPMHP_00114 94975 3 Gut 0.25 protein_coding synonymous_variant LOW 6G>A Ser2Ser
M0173620 FDPBPMHP_00105 95023 3 Gut 0.25 protein_coding upstream_gene_variant MODIFIER -4510G>A None
M0173621 FDPBPMHP_00115 95375 3 Gut 0.25 protein_coding synonymous_variant LOW 345A>C Pro115Pro
M0173622 FDPBPMHP_00115 95684 3 Gut 0.25 protein_coding synonymous_variant LOW 654C>A Thr218Thr
M0173623 FDPBPMHP_00117 96818 3 Gut 0.25 protein_coding synonymous_variant LOW 15G>A Glu5Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
FDPBPMHP_00132 VFG034602 Adhesive fimbriae 91.1 1.5e-138 1 257 1.0 1 Adherence fimbrial protein FaeJ prediction
FDPBPMHP_00133 VFG043644 CS31A capsule-like antigen 96.9 1.2e-140 1 254 1.0 1 Adherence CS31A minor subunit prediction
FDPBPMHP_00134 VFG043647 CS31A capsule-like antigen 81.6 3.9e-115 8 262 0.9733 0.9586 Adherence fimbrial protein prediction
FDPBPMHP_00136 VFG043645 CS31A capsule-like antigen 79.6 1e-65 1 162 0.9939 0.9939 Adherence unknown protein prediction
FDPBPMHP_00137 VFG043643 CS31A capsule-like antigen 92.9 5.9e-126 1 240 1.0 0.9125 Adherence unknown protein prediction
FDPBPMHP_00138 VFG042494 Adhesive fimbriae 93.2 0 15 814 0.9828 1 Adherence cshB porin (usher) prediction
FDPBPMHP_00139 VFG042533 CS31A capsule-like antigen 95.6 5e-93 1 180 1.0 1 Adherence ClpC prediction
FDPBPMHP_00140 VFG042532 CS31A capsule-like antigen 82.3 6.9e-44 5 100 0.96 0.9697 Adherence repressor protein prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
FDPBPMHP_00121 ARO:3000412 100 4.11e-186 1 271 1.0000 1.0000 sulfonamide antibiotic sulfonamide resistant sul antibiotic target replacement
FDPBPMHP_00123 ARO:3002639 99.6 5.98e-202 1 267 1.0000 1.0000 aminoglycoside antibiotic APH(3'') antibiotic inactivation
FDPBPMHP_00124 ARO:3002660 99.3 1.25e-204 1 278 1.0000 1.0000 aminoglycoside antibiotic APH(6) antibiotic inactivation






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
FDPBPMHP_00088 AKA93601.1|GH23 100 1e-123 1 169 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
FDPBPMHP_00138 1.B.11.1.1 91.9 0 5 814 0.9951 0.9975 1 Channels/Pores 1.B β-Barrel Porins 1.B.11 The Outer Membrane Fimbrial Usher Porin (FUP) Family
FDPBPMHP_00149 2.A.42.2.4 93.9 1.4e-221 17 445 0.9640 0.9684 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.42 The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family