Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C736
  Reference Plasmid   NZ_CP053760.1
  Reference Plasmid Size   2672
  Reference Plasmid GC Content   0.46
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0173816 EINNKIFJ_00001 1207 6 Gut 0.35 protein_coding upstream_gene_variant MODIFIER -755T>G None
M0173817 EINNKIFJ_00001 1214 6 Gut 0.35 protein_coding upstream_gene_variant MODIFIER -762A>G None
M0173818 EINNKIFJ_00003 1291 6 Gut 0.35 protein_coding missense_variant MODERATE 722A>G Lys241Arg
M0173819 EINNKIFJ_00003 1481 6 Gut 0.35 protein_coding missense_variant MODERATE 532T>C Tyr178His
M0173820 EINNKIFJ_00003 1730 6 Gut 0.35 protein_coding missense_variant MODERATE 283A>C Ile95Leu
M0173821 EINNKIFJ_00003 1908 6 Gut 0.35 protein_coding missense_variant MODERATE 105G>A Met35Ile
M0173822 EINNKIFJ_00001 2032 6 Gut 0.35 protein_coding upstream_gene_variant MODIFIER -1580C>A None
M0173823 EINNKIFJ_00001 2056 6 Gut 0.35 protein_coding upstream_gene_variant MODIFIER -1604G>T None
M0173824 EINNKIFJ_00001 2070 6 Gut 0.35 protein_coding upstream_gene_variant MODIFIER -1618A>G None
M0173825 EINNKIFJ_00001 318 3 Gut 0.18 protein_coding synonymous_variant LOW 135G>A Ala45Ala
M0173826 EINNKIFJ_00001 323 3 Gut 0.18 protein_coding missense_variant MODERATE 130A>C Ile44Leu
M0173827 EINNKIFJ_00001 347 3 Gut 0.18 protein_coding missense_variant MODERATE 106G>A Ala36Thr
M0173828 EINNKIFJ_00001 348 3 Gut 0.18 protein_coding synonymous_variant LOW 105C>T Ala35Ala
M0173829 EINNKIFJ_00001 360 3 Gut 0.18 protein_coding synonymous_variant LOW 93C>T Ala31Ala
M0173830 EINNKIFJ_00001 399 3 Gut 0.18 protein_coding synonymous_variant LOW 54G>A Gln18Gln
M0173831 EINNKIFJ_00001 417 3 Gut 0.18 protein_coding synonymous_variant LOW 36G>A Ala12Ala
M0173832 EINNKIFJ_00001 434 3 Gut 0.18 protein_coding missense_variant MODERATE 19A>G Thr7Ala
M0173833 EINNKIFJ_00001 457 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -5G>A None
M0173834 EINNKIFJ_00001 458 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -6A>G None
M0173835 EINNKIFJ_00001 551 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -99T>A None
M0173836 EINNKIFJ_00001 700 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -248G>A None
M0173837 EINNKIFJ_00001 714 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -262C>T None
M0173838 EINNKIFJ_00002 857 3 Gut 0.18 protein_coding synonymous_variant LOW 120T>C Ser40Ser
M0173839 EINNKIFJ_00002 890 3 Gut 0.18 protein_coding missense_variant MODERATE 153C>A Asn51Lys
M0173840 EINNKIFJ_00002 917 3 Gut 0.18 protein_coding synonymous_variant LOW 180G>A Val60Val
M0173841 EINNKIFJ_00002 978 3 Gut 0.18 protein_coding missense_variant MODERATE 241A>G Ile81Val
M0173842 EINNKIFJ_00001 1070 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -618C>T None
M0173843 EINNKIFJ_00001 1082 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -630A>G None
M0173844 EINNKIFJ_00001 1089 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -637T>A None
M0173845 EINNKIFJ_00001 1104 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -652C>G None
M0173846 EINNKIFJ_00001 1124 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -672A>T None
M0173847 EINNKIFJ_00001 1153 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -701G>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term