Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C753
  Reference Plasmid   NZ_CP055603.1
  Reference Plasmid Size   33901
  Reference Plasmid GC Content   0.50
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0174759 CEHJFKDK_00002 2529 3 Gut 1.00 protein_coding synonymous_variant LOW 447C>T Ile149Ile
M0174760 CEHJFKDK_00009 8558 3 Gut 1.00 protein_coding missense_variant MODERATE 1000G>T Ala334Ser
M0174761 CEHJFKDK_00019 14149 3 Gut 1.00 protein_coding missense_variant MODERATE 394A>G Lys132Glu
M0174762 CEHJFKDK_00020 14462 3 Gut 1.00 protein_coding missense_variant MODERATE 134T>C Leu45Pro
M0174763 CEHJFKDK_00020 14529 3 Gut 1.00 protein_coding synonymous_variant LOW 201A>G Leu67Leu
M0174764 CEHJFKDK_00023 20233 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4786C>T None
M0174765 CEHJFKDK_00023 20244 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4797T>C None
M0174766 CEHJFKDK_00023 20248 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4801G>A None
M0174767 CEHJFKDK_00033 20327 3 Gut 1.00 protein_coding synonymous_variant LOW 30C>T Asp10Asp
M0174768 CEHJFKDK_00033 20399 3 Gut 1.00 protein_coding synonymous_variant LOW 102A>C Gly34Gly
M0174769 CEHJFKDK_00033 20502 3 Gut 1.00 protein_coding synonymous_variant LOW 205T>C Leu69Leu
M0174770 CEHJFKDK_00033 20504 3 Gut 1.00 protein_coding synonymous_variant LOW 207A>G Leu69Leu
M0174771 CEHJFKDK_00033 20588 3 Gut 1.00 protein_coding synonymous_variant LOW 291A>G Gln97Gln
M0174772 CEHJFKDK_00033 20753 3 Gut 1.00 protein_coding synonymous_variant LOW 456G>A Lys152Lys
M0174773 CEHJFKDK_00033 20801 3 Gut 1.00 protein_coding synonymous_variant LOW 504A>G Leu168Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
CEHJFKDK_00029 AUO37500.1|GH24 100 2.29e-118 1 165 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
CEHJFKDK_00036 1.W.5.1.1 98.9 3.10000000000018e-311 1 533 1.0000 1.0000 1 Channels/Pores 1.W Phage Portal Protein Subclass 1.W.5 The (Lambda) Phage Portal Protein 5 (PPP5) Family