Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C758
  Reference Plasmid   NZ_CP058136.1
  Reference Plasmid Size   12557
  Reference Plasmid GC Content   0.56
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0101087 GBGEJMBF_00001 502 21 Skin 0.72 protein_coding synonymous_variant LOW 3021G>A Glu1007Glu
M0101088 GBGEJMBF_00001 521 21 Skin 0.72 protein_coding missense_variant MODERATE 3002C>A Ala1001Glu
M0101089 GBGEJMBF_00001 634 21 Skin 0.72 protein_coding synonymous_variant LOW 2889C>T Gly963Gly
M0101090 GBGEJMBF_00001 641 21 Skin 0.72 protein_coding missense_variant MODERATE 2882C>T Ala961Val
M0101091 GBGEJMBF_00001 790 21 Skin 0.72 protein_coding synonymous_variant LOW 2733A>G Ser911Ser
M0101092 GBGEJMBF_00001 799 21 Skin 0.72 protein_coding missense_variant MODERATE 2724G>T Gln908His
M0101093 GBGEJMBF_00001 835 21 Skin 0.72 protein_coding synonymous_variant LOW 2688T>G Val896Val
M0101094 GBGEJMBF_00001 853 21 Skin 0.72 protein_coding synonymous_variant LOW 2670G>A Pro890Pro
M0101095 GBGEJMBF_00001 913 21 Skin 0.72 protein_coding synonymous_variant LOW 2610G>C Ala870Ala
M0101096 GBGEJMBF_00001 925 21 Skin 0.72 protein_coding synonymous_variant LOW 2598C>G Pro866Pro
M0101097 GBGEJMBF_00001 1003 21 Skin 0.72 protein_coding synonymous_variant LOW 2520T>C Ile840Ile
M0101098 GBGEJMBF_00001 1111 21 Skin 0.72 protein_coding synonymous_variant LOW 2412A>G Glu804Glu
M0101099 GBGEJMBF_00001 1171 21 Skin 0.72 protein_coding synonymous_variant LOW 2352G>C Leu784Leu
M0101100 GBGEJMBF_00001 1846 21 Skin 0.72 protein_coding synonymous_variant LOW 1677A>G Leu559Leu
M0101101 GBGEJMBF_00001 1848 21 Skin 0.72 protein_coding synonymous_variant LOW 1675C>T Leu559Leu
M0101102 GBGEJMBF_00001 1861 21 Skin 0.72 protein_coding synonymous_variant LOW 1662C>A Gly554Gly
M0101103 GBGEJMBF_00001 1888 21 Skin 0.72 protein_coding synonymous_variant LOW 1635G>T Leu545Leu
M0101104 GBGEJMBF_00001 1899 21 Skin 0.72 protein_coding missense_variant MODERATE 1624G>T Ala542Ser
M0101105 GBGEJMBF_00001 1918 21 Skin 0.72 protein_coding synonymous_variant LOW 1605G>A Ala535Ala
M0101106 GBGEJMBF_00001 1990 21 Skin 0.72 protein_coding missense_variant MODERATE 1533T>G Asp511Glu
M0101107 GBGEJMBF_00001 2117 21 Skin 0.72 protein_coding missense_variant MODERATE 1406A>G Asp469Gly
M0101108 GBGEJMBF_00001 3367 21 Skin 0.72 protein_coding synonymous_variant LOW 156C>A Ala52Ala
M0101109 GBGEJMBF_00002 3857 23 Skin 0.79 protein_coding missense_variant MODERATE 256A>G Lys86Glu
M0101110 GBGEJMBF_00002 4050 23 Skin 0.79 protein_coding synonymous_variant LOW 63C>T Arg21Arg
M0101111 GBGEJMBF_00001 4210 23 Skin 0.79 protein_coding upstream_gene_variant MODIFIER -688G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
GBGEJMBF_00007 ARO:3000230 97.2 3.06e-130 1 177 1.0000 1.0000 aminoglycoside antibiotic ANT(2'') antibiotic inactivation






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term