Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C759
  Reference Plasmid   NZ_CP058300.1
  Reference Plasmid Size   41912
  Reference Plasmid GC Content   0.28
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0174789 HGBBDPOP_00001 60 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -54C>T None
M0174790 HGBBDPOP_00001 72 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -42A>G None
M0174791 HGBBDPOP_00001 88 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -26A>G None
M0174792 HGBBDPOP_00001 197 4 Gut 1.00 protein_coding synonymous_variant LOW 84A>G Lys28Lys
M0174793 HGBBDPOP_00001 215 4 Gut 1.00 protein_coding synonymous_variant LOW 102C>T Thr34Thr
M0174794 HGBBDPOP_00001 216 4 Gut 1.00 protein_coding missense_variant MODERATE 103G>A Val35Ile
M0174795 HGBBDPOP_00001 239 4 Gut 1.00 protein_coding synonymous_variant LOW 126T>C Asp42Asp
M0174796 HGBBDPOP_00001 298 4 Gut 1.00 protein_coding missense_variant MODERATE 185T>A Val62Asp
M0174797 HGBBDPOP_00001 310 4 Gut 1.00 protein_coding missense_variant MODERATE 197C>T Ala66Val
M0174798 HGBBDPOP_00001 323 4 Gut 1.00 protein_coding synonymous_variant LOW 210C>T Gly70Gly
M0174799 HGBBDPOP_00001 341 4 Gut 1.00 protein_coding synonymous_variant LOW 228G>A Leu76Leu
M0174800 HGBBDPOP_00001 344 4 Gut 1.00 protein_coding synonymous_variant LOW 231T>C Ile77Ile
M0174801 HGBBDPOP_00002 2251 4 Gut 1.00 protein_coding missense_variant MODERATE 1825G>A Gly609Arg
M0174802 HGBBDPOP_00002 2310 4 Gut 1.00 protein_coding synonymous_variant LOW 1884A>G Arg628Arg
M0174803 HGBBDPOP_00002 2378 4 Gut 1.00 protein_coding missense_variant MODERATE 1952A>G Asn651Ser
M0174804 HGBBDPOP_00002 2408 4 Gut 1.00 protein_coding missense_variant MODERATE 1982C>A Ser661Tyr
M0174805 HGBBDPOP_00002 2592 4 Gut 1.00 protein_coding synonymous_variant LOW 2166A>G Ala722Ala
M0174806 HGBBDPOP_00002 5223 4 Gut 1.00 protein_coding synonymous_variant LOW 4797A>G Glu1599Glu
M0174807 HGBBDPOP_00002 5226 4 Gut 1.00 protein_coding synonymous_variant LOW 4800C>T Phe1600Phe
M0174808 HGBBDPOP_00002 5358 4 Gut 1.00 protein_coding synonymous_variant LOW 4932C>T Ala1644Ala
M0174809 HGBBDPOP_00002 5568 4 Gut 1.00 protein_coding synonymous_variant LOW 5142C>T Ile1714Ile
M0174810 HGBBDPOP_00002 5652 4 Gut 1.00 protein_coding synonymous_variant LOW 5226G>A Thr1742Thr
M0174811 HGBBDPOP_00002 5655 4 Gut 1.00 protein_coding synonymous_variant LOW 5229T>C Ser1743Ser
M0174812 HGBBDPOP_00002 5659 4 Gut 1.00 protein_coding synonymous_variant LOW 5233C>T Leu1745Leu
M0174813 HGBBDPOP_00002 5841 4 Gut 1.00 protein_coding synonymous_variant LOW 5415T>C Ile1805Ile
M0174814 HGBBDPOP_00002 5880 4 Gut 1.00 protein_coding synonymous_variant LOW 5454C>T Thr1818Thr
M0174815 HGBBDPOP_00002 6084 4 Gut 1.00 protein_coding synonymous_variant LOW 5658C>T Asp1886Asp
M0174816 HGBBDPOP_00002 6132 4 Gut 1.00 protein_coding synonymous_variant LOW 5706C>T Asn1902Asn
M0174817 HGBBDPOP_00004 7026 4 Gut 1.00 protein_coding missense_variant MODERATE 1340G>T Ser447Ile
M0174818 HGBBDPOP_00004 7036 4 Gut 1.00 protein_coding missense_variant MODERATE 1330A>T Thr444Ser
M0174819 HGBBDPOP_00004 7046 4 Gut 1.00 protein_coding synonymous_variant LOW 1320A>G Lys440Lys
M0174820 HGBBDPOP_00004 7048 4 Gut 1.00 protein_coding missense_variant MODERATE 1318A>G Lys440Glu
M0174821 HGBBDPOP_00004 7055 4 Gut 1.00 protein_coding synonymous_variant LOW 1311A>G Gln437Gln
M0174822 HGBBDPOP_00004 7117 4 Gut 1.00 protein_coding missense_variant MODERATE 1249A>G Met417Val
M0174823 HGBBDPOP_00004 7204 4 Gut 1.00 protein_coding missense_variant MODERATE 1162G>A Val388Ile
M0174824 HGBBDPOP_00004 7363 4 Gut 1.00 protein_coding missense_variant MODERATE 1003A>G Ile335Val
M0174825 HGBBDPOP_00004 7376 4 Gut 1.00 protein_coding synonymous_variant LOW 990A>G Lys330Lys
M0174826 HGBBDPOP_00004 7472 4 Gut 1.00 protein_coding synonymous_variant LOW 894G>A Val298Val
M0174827 HGBBDPOP_00004 7610 4 Gut 1.00 protein_coding synonymous_variant LOW 756T>C His252His
M0174828 HGBBDPOP_00004 7651 4 Gut 1.00 protein_coding missense_variant MODERATE 715A>G Thr239Ala
M0174829 HGBBDPOP_00004 7723 4 Gut 1.00 protein_coding missense_variant MODERATE 643A>G Ile215Val
M0174830 HGBBDPOP_00004 7727 4 Gut 1.00 protein_coding synonymous_variant LOW 639G>A Leu213Leu
M0174831 HGBBDPOP_00004 7742 4 Gut 1.00 protein_coding missense_variant MODERATE 624T>A Asn208Lys
M0174832 HGBBDPOP_00004 7958 4 Gut 1.00 protein_coding synonymous_variant LOW 408T>C Ser136Ser
M0174833 HGBBDPOP_00004 8036 4 Gut 1.00 protein_coding synonymous_variant LOW 330C>T Phe110Phe
M0174834 HGBBDPOP_00004 8072 4 Gut 1.00 protein_coding synonymous_variant LOW 294T>G Ala98Ala
M0174835 HGBBDPOP_00004 8079 4 Gut 1.00 protein_coding missense_variant MODERATE 287T>G Ile96Arg
M0174836 HGBBDPOP_00004 8099 4 Gut 1.00 protein_coding synonymous_variant LOW 267A>G Leu89Leu
M0174837 HGBBDPOP_00004 8221 4 Gut 1.00 protein_coding missense_variant MODERATE 145G>A Val49Ile
M0174838 HGBBDPOP_00004 8259 4 Gut 1.00 protein_coding missense_variant MODERATE 107A>G Lys36Arg
M0174839 HGBBDPOP_00005 8662 4 Gut 1.00 protein_coding synonymous_variant LOW 255T>C Ile85Ile
M0174840 HGBBDPOP_00005 8752 4 Gut 1.00 protein_coding synonymous_variant LOW 165A>G Glu55Glu
M0174841 HGBBDPOP_00005 8836 4 Gut 1.00 protein_coding synonymous_variant LOW 81C>T Asn27Asn
M0174842 HGBBDPOP_00005 8857 4 Gut 1.00 protein_coding synonymous_variant LOW 60G>A Glu20Glu
M0174843 HGBBDPOP_00003 8930 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -1979C>T None
M0174844 HGBBDPOP_00003 9005 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2054A>G None
M0174845 HGBBDPOP_00003 9019 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2068C>T None
M0174846 HGBBDPOP_00003 9056 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2105A>G None
M0174847 HGBBDPOP_00003 9072 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2121A>G None
M0174848 HGBBDPOP_00003 9073 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2122T>C None
M0174849 HGBBDPOP_00006 9113 4 Gut 1.00 protein_coding missense_variant MODERATE 4T>C Phe2Leu
M0174850 HGBBDPOP_00006 9218 4 Gut 1.00 protein_coding missense_variant MODERATE 109T>C Phe37Leu
M0174851 HGBBDPOP_00006 9226 4 Gut 1.00 protein_coding synonymous_variant LOW 117A>G Ser39Ser
M0174852 HGBBDPOP_00006 9319 3 Gut 0.75 protein_coding synonymous_variant LOW 210C>A Ile70Ile
M0174853 HGBBDPOP_00007 9746 4 Gut 1.00 protein_coding synonymous_variant LOW 327C>T Leu109Leu
M0174854 HGBBDPOP_00007 9777 4 Gut 1.00 protein_coding missense_variant MODERATE 358A>G Ile120Val
M0174855 HGBBDPOP_00007 9792 4 Gut 1.00 protein_coding synonymous_variant LOW 373T>C Leu125Leu
M0174856 HGBBDPOP_00007 9809 4 Gut 1.00 protein_coding synonymous_variant LOW 390A>G Lys130Lys
M0174857 HGBBDPOP_00007 9812 4 Gut 1.00 protein_coding synonymous_variant LOW 393A>T Ala131Ala
M0174858 HGBBDPOP_00007 9813 4 Gut 1.00 protein_coding missense_variant MODERATE 394A>T Ile132Leu
M0174859 HGBBDPOP_00007 9827 4 Gut 1.00 protein_coding synonymous_variant LOW 408A>T Ser136Ser
M0174860 HGBBDPOP_00007 9836 4 Gut 1.00 protein_coding synonymous_variant LOW 417C>T Ala139Ala
M0174861 HGBBDPOP_00007 9846 4 Gut 1.00 protein_coding missense_variant MODERATE 427G>A Val143Ile
M0174862 HGBBDPOP_00007 9848 4 Gut 1.00 protein_coding synonymous_variant LOW 429T>A Val143Val
M0174863 HGBBDPOP_00007 9851 4 Gut 1.00 protein_coding synonymous_variant LOW 432T>A Gly144Gly
M0174864 HGBBDPOP_00007 9862 4 Gut 1.00 protein_coding missense_variant MODERATE 443T>C Leu148Ser
M0174865 HGBBDPOP_00007 9884 4 Gut 1.00 protein_coding synonymous_variant LOW 465T>A Ser155Ser
M0174866 HGBBDPOP_00007 9911 4 Gut 1.00 protein_coding synonymous_variant LOW 492G>A Lys164Lys
M0174867 HGBBDPOP_00007 9925 4 Gut 1.00 protein_coding missense_variant MODERATE 506G>A Ser169Asn
M0174868 HGBBDPOP_00007 9926 4 Gut 1.00 protein_coding missense_variant MODERATE 507T>A Ser169Arg
M0174869 HGBBDPOP_00003 9986 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -3035C>T None
M0174870 HGBBDPOP_00003 9990 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -3039C>T None
M0174871 HGBBDPOP_00003 9997 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -3046A>G None
M0174872 HGBBDPOP_00003 10003 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -3052G>A None
M0174873 HGBBDPOP_00008 10090 4 Gut 1.00 protein_coding synonymous_variant LOW 57C>T Tyr19Tyr
M0174874 HGBBDPOP_00008 10091 4 Gut 1.00 protein_coding missense_variant MODERATE 58G>A Asp20Asn
M0174875 HGBBDPOP_00008 10097 4 Gut 1.00 protein_coding missense_variant MODERATE 64A>G Asn22Asp
M0174876 HGBBDPOP_00009 10961 4 Gut 1.00 protein_coding missense_variant MODERATE 156A>T Lys52Asn
M0174877 HGBBDPOP_00009 11615 4 Gut 1.00 protein_coding synonymous_variant LOW 810T>C Ile270Ile
M0174878 HGBBDPOP_00009 11733 4 Gut 1.00 protein_coding missense_variant MODERATE 928C>G Gln310Glu
M0174879 HGBBDPOP_00009 11738 4 Gut 1.00 protein_coding synonymous_variant LOW 933C>T Asn311Asn
M0174880 HGBBDPOP_00009 11747 4 Gut 1.00 protein_coding synonymous_variant LOW 942T>A Ile314Ile
M0174881 HGBBDPOP_00009 11750 4 Gut 1.00 protein_coding synonymous_variant LOW 945C>T Thr315Thr
M0174882 HGBBDPOP_00009 11759 4 Gut 1.00 protein_coding synonymous_variant LOW 954C>A Ala318Ala
M0174883 HGBBDPOP_00009 11804 4 Gut 1.00 protein_coding synonymous_variant LOW 999A>C Gly333Gly
M0174884 HGBBDPOP_00009 11828 4 Gut 1.00 protein_coding synonymous_variant LOW 1023A>G Gln341Gln
M0174885 HGBBDPOP_00009 11833 4 Gut 1.00 protein_coding missense_variant MODERATE 1028A>G Lys343Arg
M0174886 HGBBDPOP_00009 11871 4 Gut 1.00 protein_coding missense_variant MODERATE 1066A>G Asn356Asp
M0174887 HGBBDPOP_00009 11884 4 Gut 1.00 protein_coding missense_variant MODERATE 1079A>G Glu360Gly
M0174888 HGBBDPOP_00009 11891 4 Gut 1.00 protein_coding synonymous_variant LOW 1086A>C Gly362Gly
M0174889 HGBBDPOP_00009 11892 4 Gut 1.00 protein_coding missense_variant MODERATE 1087A>G Ile363Val
M0174890 HGBBDPOP_00009 11894 4 Gut 1.00 protein_coding missense_variant MODERATE 1089A>G Ile363Met
M0174891 HGBBDPOP_00009 11903 4 Gut 1.00 protein_coding synonymous_variant LOW 1098C>T Phe366Phe
M0174892 HGBBDPOP_00009 11912 4 Gut 1.00 protein_coding synonymous_variant LOW 1107T>C Ile369Ile
M0174893 HGBBDPOP_00009 11915 4 Gut 1.00 protein_coding synonymous_variant LOW 1110T>C Phe370Phe
M0174894 HGBBDPOP_00009 11921 4 Gut 1.00 protein_coding synonymous_variant LOW 1116T>C Asn372Asn
M0174895 HGBBDPOP_00009 11927 4 Gut 1.00 protein_coding synonymous_variant LOW 1122G>A Gly374Gly
M0174896 HGBBDPOP_00009 11928 4 Gut 1.00 protein_coding missense_variant MODERATE 1123A>C Ile375Leu
M0174897 HGBBDPOP_00009 11957 4 Gut 1.00 protein_coding synonymous_variant LOW 1152C>T Phe384Phe
M0174898 HGBBDPOP_00009 11972 4 Gut 1.00 protein_coding synonymous_variant LOW 1167T>C Asn389Asn
M0174899 HGBBDPOP_00009 11982 4 Gut 1.00 protein_coding missense_variant MODERATE 1177T>G Ser393Ala
M0174900 HGBBDPOP_00004 12053 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -3688G>A None
M0174901 HGBBDPOP_00004 12100 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -3735C>T None
M0174902 HGBBDPOP_00010 12169 4 Gut 1.00 protein_coding synonymous_variant LOW 30A>G Leu10Leu
M0174903 HGBBDPOP_00010 12190 4 Gut 1.00 protein_coding synonymous_variant LOW 51T>C Val17Val
M0174904 HGBBDPOP_00010 12223 4 Gut 1.00 protein_coding synonymous_variant LOW 84A>G Val28Val
M0174905 HGBBDPOP_00012 12821 4 Gut 1.00 protein_coding synonymous_variant LOW 63T>C Phe21Phe
M0174906 HGBBDPOP_00012 12833 4 Gut 1.00 protein_coding synonymous_variant LOW 51G>A Glu17Glu
M0174907 HGBBDPOP_00012 12838 4 Gut 1.00 protein_coding synonymous_variant LOW 46T>C Leu16Leu
M0174908 HGBBDPOP_00012 12839 4 Gut 1.00 protein_coding synonymous_variant LOW 45T>C Thr15Thr
M0174909 HGBBDPOP_00012 12849 4 Gut 1.00 protein_coding missense_variant MODERATE 35A>G Lys12Arg
M0174910 HGBBDPOP_00012 12850 4 Gut 1.00 protein_coding missense_variant MODERATE 34A>G Lys12Glu
M0174911 HGBBDPOP_00012 12853 4 Gut 1.00 protein_coding missense_variant MODERATE 31A>G Thr11Ala
M0174912 HGBBDPOP_00004 12889 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4524A>G None
M0174913 HGBBDPOP_00004 12901 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4536A>G None
M0174914 HGBBDPOP_00004 12902 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4537A>G None
M0174915 HGBBDPOP_00013 12949 4 Gut 1.00 protein_coding missense_variant MODERATE 154A>G Asn52Asp
M0174916 HGBBDPOP_00013 12963 4 Gut 1.00 protein_coding missense_variant MODERATE 140C>T Thr47Ile
M0174917 HGBBDPOP_00013 13028 4 Gut 1.00 protein_coding missense_variant MODERATE 75A>T Leu25Phe
M0174918 HGBBDPOP_00013 13029 4 Gut 1.00 protein_coding missense_variant MODERATE 74T>C Leu25Ser
M0174919 HGBBDPOP_00013 13038 4 Gut 1.00 protein_coding missense_variant MODERATE 65C>T Ser22Leu
M0174920 HGBBDPOP_00013 13054 4 Gut 1.00 protein_coding missense_variant MODERATE 49C>T Pro17Ser
M0174921 HGBBDPOP_00013 13056 4 Gut 1.00 protein_coding missense_variant MODERATE 47T>C Ile16Thr
M0174922 HGBBDPOP_00004 13131 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4766G>A None
M0174923 HGBBDPOP_00004 13152 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4787G>A None
M0174924 HGBBDPOP_00004 13224 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4859T>C None
M0174925 HGBBDPOP_00004 13225 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4860G>A None
M0174926 HGBBDPOP_00004 13245 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4880A>G None
M0174927 HGBBDPOP_00004 13354 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4989A>G None
M0174928 HGBBDPOP_00004 13363 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4998G>C None
M0174929 HGBBDPOP_00005 13371 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4455A>G None
M0174930 HGBBDPOP_00014 13539 4 Gut 1.00 protein_coding synonymous_variant LOW 165G>A Arg55Arg
M0174931 HGBBDPOP_00014 13554 4 Gut 1.00 protein_coding synonymous_variant LOW 180A>G Lys60Lys
M0174932 HGBBDPOP_00005 13686 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4770A>G None
M0174933 HGBBDPOP_00015 13785 4 Gut 1.00 protein_coding missense_variant MODERATE 24T>A Asp8Glu
M0174934 HGBBDPOP_00015 13801 4 Gut 1.00 protein_coding missense_variant MODERATE 40A>C Ile14Leu
M0174935 HGBBDPOP_00015 13809 4 Gut 1.00 protein_coding synonymous_variant LOW 48T>C Ser16Ser
M0174936 HGBBDPOP_00015 13842 4 Gut 1.00 protein_coding synonymous_variant LOW 81A>G Thr27Thr
M0174937 HGBBDPOP_00015 13849 4 Gut 1.00 protein_coding synonymous_variant LOW 88C>T Leu30Leu
M0174938 HGBBDPOP_00015 13851 4 Gut 1.00 protein_coding synonymous_variant LOW 90G>A Leu30Leu
M0174939 HGBBDPOP_00015 13860 4 Gut 1.00 protein_coding synonymous_variant LOW 99C>T Gly33Gly
M0174940 HGBBDPOP_00015 14061 4 Gut 1.00 protein_coding synonymous_variant LOW 300T>C Leu100Leu
M0174941 HGBBDPOP_00015 14230 4 Gut 1.00 protein_coding missense_variant MODERATE 469G>A Val157Ile
M0174942 HGBBDPOP_00015 14256 4 Gut 1.00 protein_coding synonymous_variant LOW 495T>C Ile165Ile
M0174943 HGBBDPOP_00015 14355 4 Gut 1.00 protein_coding synonymous_variant LOW 594A>G Lys198Lys
M0174944 HGBBDPOP_00015 14394 4 Gut 1.00 protein_coding synonymous_variant LOW 633A>G Glu211Glu
M0174945 HGBBDPOP_00015 14454 4 Gut 1.00 protein_coding synonymous_variant LOW 693A>G Leu231Leu
M0174946 HGBBDPOP_00015 14496 4 Gut 1.00 protein_coding synonymous_variant LOW 735A>G Arg245Arg
M0174947 HGBBDPOP_00015 14502 4 Gut 1.00 protein_coding synonymous_variant LOW 741T>C Asn247Asn
M0174948 HGBBDPOP_00015 15102 4 Gut 1.00 protein_coding synonymous_variant LOW 1341A>G Arg447Arg
M0174949 HGBBDPOP_00015 15132 4 Gut 1.00 protein_coding synonymous_variant LOW 1371T>C Ser457Ser
M0174950 HGBBDPOP_00015 15135 4 Gut 1.00 protein_coding synonymous_variant LOW 1374C>T Thr458Thr
M0174951 HGBBDPOP_00015 15162 4 Gut 1.00 protein_coding synonymous_variant LOW 1401A>G Lys467Lys
M0174952 HGBBDPOP_00015 15186 4 Gut 1.00 protein_coding synonymous_variant LOW 1425G>A Leu475Leu
M0174953 HGBBDPOP_00015 15201 4 Gut 1.00 protein_coding synonymous_variant LOW 1440A>G Leu480Leu
M0174954 HGBBDPOP_00015 15222 4 Gut 1.00 protein_coding synonymous_variant LOW 1461T>C Phe487Phe
M0174955 HGBBDPOP_00015 15297 4 Gut 1.00 protein_coding synonymous_variant LOW 1536T>C Ile512Ile
M0174956 HGBBDPOP_00012 15616 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2733A>G None
M0174957 HGBBDPOP_00012 15620 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2737T>C None
M0174958 HGBBDPOP_00012 15669 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2786A>G None
M0174959 HGBBDPOP_00012 15670 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2787A>T None
M0174960 HGBBDPOP_00016 15715 4 Gut 1.00 protein_coding synonymous_variant LOW 585C>T Phe195Phe
M0174961 HGBBDPOP_00016 15754 4 Gut 1.00 protein_coding synonymous_variant LOW 546C>T Tyr182Tyr
M0174962 HGBBDPOP_00016 15772 4 Gut 1.00 protein_coding synonymous_variant LOW 528T>C Ser176Ser
M0174963 HGBBDPOP_00016 15778 4 Gut 1.00 protein_coding synonymous_variant LOW 522C>T Ile174Ile
M0174964 HGBBDPOP_00016 15811 4 Gut 1.00 protein_coding synonymous_variant LOW 489G>A Lys163Lys
M0174965 HGBBDPOP_00016 15814 4 Gut 1.00 protein_coding synonymous_variant LOW 486C>T Asp162Asp
M0174966 HGBBDPOP_00016 15823 4 Gut 1.00 protein_coding synonymous_variant LOW 477A>G Lys159Lys
M0174967 HGBBDPOP_00016 15841 4 Gut 1.00 protein_coding synonymous_variant LOW 459T>A Leu153Leu
M0174968 HGBBDPOP_00016 15843 4 Gut 1.00 protein_coding missense_variant MODERATE 457C>T Leu153Phe
M0174969 HGBBDPOP_00016 15846 4 Gut 1.00 protein_coding missense_variant MODERATE 454A>T Thr152Ser
M0174970 HGBBDPOP_00016 15847 4 Gut 1.00 protein_coding synonymous_variant LOW 453A>G Gly151Gly
M0174971 HGBBDPOP_00016 15850 4 Gut 1.00 protein_coding missense_variant MODERATE 450G>A Met150Ile
M0174972 HGBBDPOP_00016 15851 4 Gut 1.00 protein_coding missense_variant MODERATE 449T>A Met150Lys
M0174973 HGBBDPOP_00016 15853 4 Gut 1.00 protein_coding synonymous_variant LOW 447T>G Pro149Pro
M0174974 HGBBDPOP_00016 15856 4 Gut 1.00 protein_coding synonymous_variant LOW 444T>C Arg148Arg
M0174975 HGBBDPOP_00016 15859 4 Gut 1.00 protein_coding synonymous_variant LOW 441G>A Gly147Gly
M0174976 HGBBDPOP_00016 15925 4 Gut 1.00 protein_coding synonymous_variant LOW 375A>G Arg125Arg
M0174977 HGBBDPOP_00016 16183 4 Gut 1.00 protein_coding synonymous_variant LOW 117G>A Val39Val
M0174978 HGBBDPOP_00017 16353 4 Gut 1.00 protein_coding synonymous_variant LOW 351T>C Phe117Phe
M0174979 HGBBDPOP_00018 16718 4 Gut 1.00 protein_coding synonymous_variant LOW 300T>C Ala100Ala
M0174980 HGBBDPOP_00018 16736 4 Gut 1.00 protein_coding synonymous_variant LOW 282A>G Leu94Leu
M0174981 HGBBDPOP_00012 17101 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4218A>G None
M0174982 HGBBDPOP_00012 17108 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4225A>G None
M0174983 HGBBDPOP_00012 17137 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4254G>A None
M0174984 HGBBDPOP_00012 17149 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4266G>A None
M0174985 HGBBDPOP_00012 17159 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4276G>A None
M0174986 HGBBDPOP_00020 17490 4 Gut 1.00 protein_coding synonymous_variant LOW 27C>T Gly9Gly
M0174987 HGBBDPOP_00020 17502 4 Gut 1.00 protein_coding synonymous_variant LOW 39C>A Pro13Pro
M0174988 HGBBDPOP_00020 17544 4 Gut 1.00 protein_coding synonymous_variant LOW 81A>G Ala27Ala
M0174989 HGBBDPOP_00020 17551 4 Gut 1.00 protein_coding missense_variant MODERATE 88A>T Ser30Cys
M0174990 HGBBDPOP_00020 17556 4 Gut 1.00 protein_coding synonymous_variant LOW 93T>C Ile31Ile
M0174991 HGBBDPOP_00020 17563 4 Gut 1.00 protein_coding missense_variant MODERATE 100G>A Val34Ile
M0174992 HGBBDPOP_00020 17568 4 Gut 1.00 protein_coding synonymous_variant LOW 105G>A Ala35Ala
M0174993 HGBBDPOP_00020 17642 4 Gut 1.00 protein_coding missense_variant MODERATE 179G>A Arg60Lys
M0174994 HGBBDPOP_00020 17649 4 Gut 1.00 protein_coding synonymous_variant LOW 186T>C Asp62Asp
M0174995 HGBBDPOP_00020 17659 4 Gut 1.00 protein_coding synonymous_variant LOW 196C>A Arg66Arg
M0174996 HGBBDPOP_00020 17688 4 Gut 1.00 protein_coding missense_variant MODERATE 225C>A Phe75Leu
M0174997 HGBBDPOP_00020 17691 4 Gut 1.00 protein_coding synonymous_variant LOW 228T>C Ser76Ser
M0174998 HGBBDPOP_00020 17700 4 Gut 1.00 protein_coding synonymous_variant LOW 237G>T Ala79Ala
M0174999 HGBBDPOP_00020 17703 4 Gut 1.00 protein_coding synonymous_variant LOW 240T>C Ser80Ser
M0175000 HGBBDPOP_00020 17706 4 Gut 1.00 protein_coding synonymous_variant LOW 243G>A Lys81Lys
M0175001 HGBBDPOP_00020 17713 4 Gut 1.00 protein_coding missense_variant MODERATE 250T>C Tyr84His
M0175002 HGBBDPOP_00020 17718 4 Gut 1.00 protein_coding synonymous_variant LOW 255A>G Lys85Lys
M0175003 HGBBDPOP_00020 17720 4 Gut 1.00 protein_coding missense_variant MODERATE 257C>T Ala86Val
M0175004 HGBBDPOP_00020 17730 4 Gut 1.00 protein_coding synonymous_variant LOW 267T>C Tyr89Tyr
M0175005 HGBBDPOP_00020 17739 4 Gut 1.00 protein_coding synonymous_variant LOW 276T>C Asn92Asn
M0175006 HGBBDPOP_00020 17757 4 Gut 1.00 protein_coding synonymous_variant LOW 294A>G Pro98Pro
M0175007 HGBBDPOP_00020 17787 4 Gut 1.00 protein_coding synonymous_variant LOW 324T>G Val108Val
M0175008 HGBBDPOP_00020 17810 4 Gut 1.00 protein_coding missense_variant MODERATE 347A>G Asn116Ser
M0175009 HGBBDPOP_00020 17838 4 Gut 1.00 protein_coding synonymous_variant LOW 375A>G Ser125Ser
M0175010 HGBBDPOP_00020 17841 4 Gut 1.00 protein_coding synonymous_variant LOW 378A>T Leu126Leu
M0175011 HGBBDPOP_00020 17847 4 Gut 1.00 protein_coding synonymous_variant LOW 384C>T Asn128Asn
M0175012 HGBBDPOP_00020 17852 4 Gut 1.00 protein_coding missense_variant MODERATE 389C>T Ser130Phe
M0175013 HGBBDPOP_00020 17856 4 Gut 1.00 protein_coding synonymous_variant LOW 393A>G Val131Val
M0175014 HGBBDPOP_00020 17859 4 Gut 1.00 protein_coding synonymous_variant LOW 396C>A Val132Val
M0175015 HGBBDPOP_00020 17875 4 Gut 1.00 protein_coding missense_variant MODERATE 412C>T Leu138Phe
M0175016 HGBBDPOP_00020 17925 4 Gut 1.00 protein_coding missense_variant MODERATE 462T>A Asp154Glu
M0175017 HGBBDPOP_00020 17928 4 Gut 1.00 protein_coding synonymous_variant LOW 465T>C Asp155Asp
M0175018 HGBBDPOP_00020 17934 4 Gut 1.00 protein_coding synonymous_variant LOW 471G>A Glu157Glu
M0175019 HGBBDPOP_00020 17967 4 Gut 1.00 protein_coding synonymous_variant LOW 504A>T Leu168Leu
M0175020 HGBBDPOP_00020 17976 4 Gut 1.00 protein_coding synonymous_variant LOW 513A>T Ser171Ser
M0175021 HGBBDPOP_00020 17980 4 Gut 1.00 protein_coding missense_variant MODERATE 517G>T Ala173Ser
M0175022 HGBBDPOP_00020 17982 4 Gut 1.00 protein_coding synonymous_variant LOW 519A>T Ala173Ala
M0175023 HGBBDPOP_00020 17985 4 Gut 1.00 protein_coding synonymous_variant LOW 522T>C Asn174Asn
M0175024 HGBBDPOP_00020 17989 4 Gut 1.00 protein_coding missense_variant MODERATE 526C>T Pro176Ser
M0175025 HGBBDPOP_00020 18045 4 Gut 1.00 protein_coding synonymous_variant LOW 582G>A Ser194Ser
M0175026 HGBBDPOP_00020 18192 4 Gut 1.00 protein_coding synonymous_variant LOW 729C>T Ser243Ser
M0175027 HGBBDPOP_00020 18221 4 Gut 1.00 protein_coding missense_variant MODERATE 758G>A Ser253Asn
M0175028 HGBBDPOP_00020 18223 4 Gut 1.00 protein_coding missense_variant MODERATE 760G>C Val254Leu
M0175029 HGBBDPOP_00020 18294 4 Gut 1.00 protein_coding synonymous_variant LOW 831A>G Arg277Arg
M0175030 HGBBDPOP_00020 18331 4 Gut 1.00 protein_coding missense_variant MODERATE 868A>G Lys290Glu
M0175031 HGBBDPOP_00020 18357 4 Gut 1.00 protein_coding synonymous_variant LOW 894A>G Leu298Leu
M0175032 HGBBDPOP_00020 18358 4 Gut 1.00 protein_coding missense_variant MODERATE 895C>A Leu299Ile
M0175033 HGBBDPOP_00020 18361 4 Gut 1.00 protein_coding missense_variant MODERATE 898G>A Gly300Ser
M0175034 HGBBDPOP_00020 18363 4 Gut 1.00 protein_coding synonymous_variant LOW 900T>C Gly300Gly
M0175035 HGBBDPOP_00020 18411 4 Gut 1.00 protein_coding synonymous_variant LOW 948C>T Tyr316Tyr
M0175036 HGBBDPOP_00020 18495 4 Gut 1.00 protein_coding synonymous_variant LOW 1032G>A Arg344Arg
M0175037 HGBBDPOP_00020 18498 4 Gut 1.00 protein_coding synonymous_variant LOW 1035T>C Cys345Cys
M0175038 HGBBDPOP_00020 18513 4 Gut 1.00 protein_coding synonymous_variant LOW 1050T>C Asp350Asp
M0175039 HGBBDPOP_00020 18522 4 Gut 1.00 protein_coding synonymous_variant LOW 1059C>T Asn353Asn
M0175040 HGBBDPOP_00020 18732 4 Gut 1.00 protein_coding synonymous_variant LOW 1269T>C Phe423Phe
M0175041 HGBBDPOP_00020 18735 4 Gut 1.00 protein_coding synonymous_variant LOW 1272C>T Gly424Gly
M0175042 HGBBDPOP_00022 21432 4 Gut 1.00 protein_coding missense_variant MODERATE 637G>A Glu213Lys
M0175043 HGBBDPOP_00023 21540 4 Gut 1.00 protein_coding missense_variant MODERATE 46G>A Val16Ile
M0175044 HGBBDPOP_00023 21686 4 Gut 1.00 protein_coding synonymous_variant LOW 192A>G Thr64Thr
M0175045 HGBBDPOP_00023 21704 4 Gut 1.00 protein_coding synonymous_variant LOW 210T>A Ser70Ser
M0175046 HGBBDPOP_00023 21778 4 Gut 1.00 protein_coding missense_variant MODERATE 284C>G Thr95Ser
M0175047 HGBBDPOP_00023 21800 4 Gut 1.00 protein_coding synonymous_variant LOW 306T>C Tyr102Tyr
M0175048 HGBBDPOP_00023 21829 4 Gut 1.00 protein_coding missense_variant MODERATE 335A>C Asn112Thr
M0175049 HGBBDPOP_00023 21851 4 Gut 1.00 protein_coding synonymous_variant LOW 357C>T Val119Val
M0175050 HGBBDPOP_00024 21971 4 Gut 1.00 protein_coding synonymous_variant LOW 36G>A Ala12Ala
M0175051 HGBBDPOP_00024 22033 4 Gut 1.00 protein_coding missense_variant MODERATE 98A>G Asn33Ser
M0175052 HGBBDPOP_00024 22115 4 Gut 1.00 protein_coding synonymous_variant LOW 180T>C Ser60Ser
M0175053 HGBBDPOP_00025 22378 4 Gut 1.00 protein_coding missense_variant MODERATE 164T>C Phe55Ser
M0175054 HGBBDPOP_00025 22513 4 Gut 1.00 protein_coding missense_variant MODERATE 299T>C Val100Ala
M0175055 HGBBDPOP_00025 22717 4 Gut 1.00 protein_coding missense_variant MODERATE 503T>C Val168Ala
M0175056 HGBBDPOP_00025 22934 4 Gut 1.00 protein_coding synonymous_variant LOW 720G>A Thr240Thr
M0175057 HGBBDPOP_00025 22940 4 Gut 1.00 protein_coding synonymous_variant LOW 726T>C Ser242Ser
M0175058 HGBBDPOP_00025 23006 4 Gut 1.00 protein_coding synonymous_variant LOW 792T>C Val264Val
M0175059 HGBBDPOP_00025 23018 4 Gut 1.00 protein_coding synonymous_variant LOW 804T>C Ile268Ile
M0175060 HGBBDPOP_00025 23021 4 Gut 1.00 protein_coding synonymous_variant LOW 807G>A Gln269Gln
M0175061 HGBBDPOP_00025 23024 4 Gut 1.00 protein_coding synonymous_variant LOW 810G>A Leu270Leu
M0175062 HGBBDPOP_00025 23030 4 Gut 1.00 protein_coding synonymous_variant LOW 816G>A Val272Val
M0175063 HGBBDPOP_00026 23953 4 Gut 1.00 protein_coding synonymous_variant LOW 771C>T Ala257Ala
M0175064 HGBBDPOP_00026 23960 4 Gut 1.00 protein_coding missense_variant MODERATE 778G>A Val260Ile
M0175065 HGBBDPOP_00026 23962 4 Gut 1.00 protein_coding synonymous_variant LOW 780T>C Val260Val
M0175066 HGBBDPOP_00026 24041 4 Gut 1.00 protein_coding missense_variant MODERATE 859G>A Ala287Thr
M0175067 HGBBDPOP_00026 24160 4 Gut 1.00 protein_coding synonymous_variant LOW 978A>G Glu326Glu
M0175068 HGBBDPOP_00027 24266 4 Gut 1.00 protein_coding synonymous_variant LOW 96C>T Asn32Asn
M0175069 HGBBDPOP_00027 24278 4 Gut 1.00 protein_coding synonymous_variant LOW 108A>G Gly36Gly
M0175070 HGBBDPOP_00027 24287 4 Gut 1.00 protein_coding synonymous_variant LOW 117T>C Pro39Pro
M0175071 HGBBDPOP_00027 24288 4 Gut 1.00 protein_coding missense_variant MODERATE 118G>A Val40Ile
M0175072 HGBBDPOP_00027 24290 4 Gut 1.00 protein_coding synonymous_variant LOW 120T>C Val40Val
M0175073 HGBBDPOP_00029 25568 4 Gut 1.00 protein_coding synonymous_variant LOW 582T>C Gly194Gly
M0175074 HGBBDPOP_00030 25876 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -25A>G None
M0175075 HGBBDPOP_00030 25878 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -23G>A None
M0175076 HGBBDPOP_00030 26227 4 Gut 1.00 protein_coding synonymous_variant LOW 327C>A Pro109Pro
M0175077 HGBBDPOP_00030 26482 4 Gut 1.00 protein_coding synonymous_variant LOW 582G>A Leu194Leu
M0175078 HGBBDPOP_00030 26497 4 Gut 1.00 protein_coding synonymous_variant LOW 597C>T Tyr199Tyr
M0175079 HGBBDPOP_00030 26617 4 Gut 1.00 protein_coding synonymous_variant LOW 717C>T Thr239Thr
M0175080 HGBBDPOP_00031 27992 4 Gut 1.00 protein_coding synonymous_variant LOW 939C>T Ala313Ala
M0175081 HGBBDPOP_00032 28272 4 Gut 1.00 protein_coding missense_variant MODERATE 226G>A Val76Ile
M0175082 HGBBDPOP_00032 28544 4 Gut 1.00 protein_coding synonymous_variant LOW 498C>T Tyr166Tyr
M0175083 HGBBDPOP_00032 28916 4 Gut 1.00 protein_coding synonymous_variant LOW 870A>T Gly290Gly
M0175084 HGBBDPOP_00032 29396 4 Gut 1.00 protein_coding synonymous_variant LOW 1350A>G Pro450Pro
M0175085 HGBBDPOP_00032 29660 4 Gut 1.00 protein_coding synonymous_variant LOW 1614T>C Ser538Ser
M0175086 HGBBDPOP_00033 29867 4 Gut 1.00 protein_coding missense_variant MODERATE 29T>C Val10Ala
M0175087 HGBBDPOP_00033 29901 4 Gut 1.00 protein_coding synonymous_variant LOW 63C>T Cys21Cys
M0175088 HGBBDPOP_00034 30814 4 Gut 1.00 protein_coding missense_variant MODERATE 527A>G Glu176Gly
M0175089 HGBBDPOP_00035 31164 4 Gut 1.00 protein_coding missense_variant MODERATE 110A>C Glu37Ala
M0175090 HGBBDPOP_00035 31318 4 Gut 1.00 protein_coding synonymous_variant LOW 264T>C Pro88Pro
M0175091 HGBBDPOP_00035 31509 4 Gut 1.00 protein_coding missense_variant MODERATE 455C>T Thr152Ile
M0175092 HGBBDPOP_00035 31554 4 Gut 1.00 protein_coding missense_variant MODERATE 500C>T Thr167Ile
M0175093 HGBBDPOP_00035 31561 4 Gut 1.00 protein_coding synonymous_variant LOW 507A>G Ser169Ser
M0175094 HGBBDPOP_00035 31756 4 Gut 1.00 protein_coding synonymous_variant LOW 702T>C Ser234Ser
M0175095 HGBBDPOP_00037 32082 4 Gut 1.00 protein_coding missense_variant MODERATE 160G>A Ala54Thr
M0175096 HGBBDPOP_00037 32243 4 Gut 1.00 protein_coding synonymous_variant LOW 321C>T Tyr107Tyr
M0175097 HGBBDPOP_00038 32556 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -251C>T None
M0175098 HGBBDPOP_00038 32557 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -250A>T None
M0175099 HGBBDPOP_00038 32558 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -249T>A None
M0175100 HGBBDPOP_00038 32559 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -248A>T None
M0175101 HGBBDPOP_00038 32675 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -132A>G None
M0175102 HGBBDPOP_00038 32680 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -127T>C None
M0175103 HGBBDPOP_00038 32860 4 Gut 1.00 protein_coding synonymous_variant LOW 54A>G Gly18Gly
M0175104 HGBBDPOP_00038 32861 4 Gut 1.00 protein_coding synonymous_variant LOW 55C>T Leu19Leu
M0175105 HGBBDPOP_00038 32932 4 Gut 1.00 protein_coding synonymous_variant LOW 126G>A Gly42Gly
M0175106 HGBBDPOP_00038 32950 4 Gut 1.00 protein_coding synonymous_variant LOW 144G>T Ala48Ala
M0175107 HGBBDPOP_00038 32983 4 Gut 1.00 protein_coding synonymous_variant LOW 177A>G Leu59Leu
M0175108 HGBBDPOP_00038 33115 4 Gut 1.00 protein_coding synonymous_variant LOW 309G>T Gly103Gly
M0175109 HGBBDPOP_00038 33121 4 Gut 1.00 protein_coding synonymous_variant LOW 315A>T Ala105Ala
M0175110 HGBBDPOP_00038 33124 4 Gut 1.00 protein_coding synonymous_variant LOW 318T>C Asp106Asp
M0175111 HGBBDPOP_00038 33130 4 Gut 1.00 protein_coding synonymous_variant LOW 324G>A Glu108Glu
M0175112 HGBBDPOP_00038 33145 4 Gut 1.00 protein_coding synonymous_variant LOW 339T>C Val113Val
M0175113 HGBBDPOP_00038 33199 4 Gut 1.00 protein_coding synonymous_variant LOW 393T>C Ile131Ile
M0175114 HGBBDPOP_00038 33313 4 Gut 1.00 protein_coding synonymous_variant LOW 507A>T Val169Val
M0175115 HGBBDPOP_00038 33316 4 Gut 1.00 protein_coding synonymous_variant LOW 510C>G Gly170Gly
M0175116 HGBBDPOP_00038 33334 4 Gut 1.00 protein_coding synonymous_variant LOW 528G>T Ala176Ala
M0175117 HGBBDPOP_00038 33337 4 Gut 1.00 protein_coding synonymous_variant LOW 531T>C Tyr177Tyr
M0175118 HGBBDPOP_00038 33367 4 Gut 1.00 protein_coding synonymous_variant LOW 561G>A Glu187Glu
M0175119 HGBBDPOP_00038 33371 4 Gut 1.00 protein_coding missense_variant MODERATE 565A>G Ile189Val
M0175120 HGBBDPOP_00038 33379 4 Gut 1.00 protein_coding synonymous_variant LOW 573C>T Ser191Ser
M0175121 HGBBDPOP_00038 33397 4 Gut 1.00 protein_coding synonymous_variant LOW 591G>A Thr197Thr
M0175122 HGBBDPOP_00038 33407 4 Gut 1.00 protein_coding missense_variant MODERATE 601T>G Ser201Ala
M0175123 HGBBDPOP_00038 33455 4 Gut 1.00 protein_coding missense_variant MODERATE 649A>G Asn217Asp
M0175124 HGBBDPOP_00038 33469 4 Gut 1.00 protein_coding synonymous_variant LOW 663G>A Leu221Leu
M0175125 HGBBDPOP_00038 33481 4 Gut 1.00 protein_coding synonymous_variant LOW 675T>C Phe225Phe
M0175126 HGBBDPOP_00038 33554 4 Gut 1.00 protein_coding missense_variant MODERATE 748G>A Glu250Lys
M0175127 HGBBDPOP_00038 33616 4 Gut 1.00 protein_coding synonymous_variant LOW 810G>A Lys270Lys
M0175128 HGBBDPOP_00038 33714 4 Gut 1.00 protein_coding missense_variant MODERATE 908T>A Ile303Asn
M0175129 HGBBDPOP_00038 33730 4 Gut 1.00 protein_coding synonymous_variant LOW 924C>T His308His
M0175130 HGBBDPOP_00038 33760 4 Gut 1.00 protein_coding synonymous_variant LOW 954C>T Cys318Cys
M0175131 HGBBDPOP_00038 33934 4 Gut 1.00 protein_coding synonymous_variant LOW 1128C>A Thr376Thr
M0175132 HGBBDPOP_00038 33940 4 Gut 1.00 protein_coding synonymous_variant LOW 1134T>C Asn378Asn
M0175133 HGBBDPOP_00038 33982 4 Gut 1.00 protein_coding synonymous_variant LOW 1176C>T Tyr392Tyr
M0175134 HGBBDPOP_00038 34009 4 Gut 1.00 protein_coding synonymous_variant LOW 1203C>T Ile401Ile
M0175135 HGBBDPOP_00038 34039 4 Gut 1.00 protein_coding synonymous_variant LOW 1233T>C Thr411Thr
M0175136 HGBBDPOP_00038 34050 4 Gut 1.00 protein_coding missense_variant MODERATE 1244A>G Asn415Ser
M0175137 HGBBDPOP_00038 34077 4 Gut 1.00 protein_coding missense_variant MODERATE 1271C>T Thr424Ile
M0175138 HGBBDPOP_00038 34223 4 Gut 1.00 protein_coding missense_variant MODERATE 1417C>G Gln473Glu
M0175139 HGBBDPOP_00038 34762 4 Gut 1.00 protein_coding synonymous_variant LOW 1956T>C Ser652Ser
M0175140 HGBBDPOP_00038 34967 4 Gut 1.00 protein_coding missense_variant MODERATE 2161A>G Asn721Asp
M0175141 HGBBDPOP_00038 34973 4 Gut 1.00 protein_coding missense_variant MODERATE 2167A>G Arg723Gly
M0175142 HGBBDPOP_00039 35013 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -92A>T None
M0175143 HGBBDPOP_00039 35017 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -88A>T None
M0175144 HGBBDPOP_00039 35021 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -84A>T None
M0175145 HGBBDPOP_00039 35562 4 Gut 1.00 protein_coding missense_variant MODERATE 458A>G Lys153Arg
M0175146 HGBBDPOP_00039 35969 4 Gut 1.00 protein_coding missense_variant MODERATE 865G>A Glu289Lys
M0175147 HGBBDPOP_00041 36959 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -124A>G None
M0175148 HGBBDPOP_00041 37073 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -10A>G None
M0175149 HGBBDPOP_00041 37074 4 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -9G>A None
M0175150 HGBBDPOP_00041 37762 4 Gut 1.00 protein_coding missense_variant MODERATE 680C>T Thr227Ile
M0175151 HGBBDPOP_00041 37765 4 Gut 1.00 protein_coding missense_variant MODERATE 683G>A Arg228Gln
M0175152 HGBBDPOP_00041 37871 4 Gut 1.00 protein_coding synonymous_variant LOW 789G>T Arg263Arg
M0175153 HGBBDPOP_00041 37966 4 Gut 1.00 protein_coding missense_variant MODERATE 884A>G Tyr295Cys
M0175154 HGBBDPOP_00041 38118 4 Gut 1.00 protein_coding missense_variant MODERATE 1036A>C Ile346Leu
M0175155 HGBBDPOP_00041 38865 4 Gut 1.00 protein_coding missense_variant MODERATE 1783T>A Tyr595Asn
M0175156 HGBBDPOP_00041 38978 4 Gut 1.00 protein_coding synonymous_variant LOW 1896G>A Arg632Arg
M0175157 HGBBDPOP_00040 41561 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *4837T>C None
M0175158 HGBBDPOP_00040 41579 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *4855A>G None
M0175159 HGBBDPOP_00040 41609 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *4885A>G None
M0175160 HGBBDPOP_00040 41651 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *4927G>T None
M0175161 HGBBDPOP_00040 41666 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *4942A>G None
M0175162 HGBBDPOP_00040 41672 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *4948G>A None
M0175163 HGBBDPOP_00040 41703 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *4979G>A None
M0175164 HGBBDPOP_00040 41723 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *4999T>C None
M0175165 HGBBDPOP_00041 41744 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *2742A>G None
M0175166 HGBBDPOP_00041 41756 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *2754C>T None
M0175167 HGBBDPOP_00041 41773 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *2771G>A None
M0175168 HGBBDPOP_00041 41776 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *2774A>G None
M0175169 HGBBDPOP_00041 41786 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *2784T>C None
M0175170 HGBBDPOP_00041 41789 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *2787A>G None
M0175171 HGBBDPOP_00041 41798 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *2796C>T None
M0175172 HGBBDPOP_00041 41816 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *2814A>G None
M0175173 HGBBDPOP_00041 41821 4 Gut 1.00 protein_coding downstream_gene_variant MODIFIER *2819A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
HGBBDPOP_00041 ARO:3000190 100 0 1 639 1.0000 1.0000 tetracycline antibiotic tetracycline-resistant ribosomal protection protein antibiotic target protection






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term