Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C765
  Reference Plasmid   NZ_CP059303.1
  Reference Plasmid Size   12651
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0101112 IGLJDEHD_00001 5191 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -3833G>A None
M0101113 IGLJDEHD_00001 5199 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -3841C>G None
M0101114 IGLJDEHD_00001 5201 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -3843A>C None
M0101115 IGLJDEHD_00001 5205 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -3847C>T None
M0101116 IGLJDEHD_00007 5230 3 Skin 0.60 protein_coding synonymous_variant LOW 375G>A Leu125Leu
M0101117 IGLJDEHD_00007 5257 3 Skin 0.60 protein_coding synonymous_variant LOW 348A>C Thr116Thr
M0101118 IGLJDEHD_00007 5258 3 Skin 0.60 protein_coding missense_variant MODERATE 347C>T Thr116Ile
M0101119 IGLJDEHD_00007 5269 3 Skin 0.60 protein_coding synonymous_variant LOW 336T>A Val112Val
M0101120 IGLJDEHD_00007 5284 3 Skin 0.60 protein_coding synonymous_variant LOW 321A>G Leu107Leu
M0101121 IGLJDEHD_00007 5293 3 Skin 0.60 protein_coding synonymous_variant LOW 312C>T Ala104Ala
M0101122 IGLJDEHD_00007 5305 3 Skin 0.60 protein_coding synonymous_variant LOW 300T>C Ile100Ile
M0101123 IGLJDEHD_00007 5341 3 Skin 0.60 protein_coding synonymous_variant LOW 264T>C Ser88Ser
M0101124 IGLJDEHD_00007 5352 3 Skin 0.60 protein_coding missense_variant MODERATE 253A>G Asn85Asp
M0101125 IGLJDEHD_00007 5379 3 Skin 0.60 protein_coding missense_variant MODERATE 226A>G Ile76Val
M0101126 IGLJDEHD_00007 5380 3 Skin 0.60 protein_coding synonymous_variant LOW 225C>A Ala75Ala
M0101127 IGLJDEHD_00007 5383 3 Skin 0.60 protein_coding synonymous_variant LOW 222G>A Gln74Gln
M0101128 IGLJDEHD_00008 5610 3 Skin 0.60 protein_coding synonymous_variant LOW 222G>A Glu74Glu
M0101129 IGLJDEHD_00008 5628 3 Skin 0.60 protein_coding synonymous_variant LOW 204G>C Gly68Gly
M0101130 IGLJDEHD_00008 5631 3 Skin 0.60 protein_coding synonymous_variant LOW 201G>A Gln67Gln
M0101131 IGLJDEHD_00001 5847 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4489G>A None
M0101132 IGLJDEHD_00001 5864 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4506C>T None
M0101133 IGLJDEHD_00001 5866 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4508G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
IGLJDEHD_00001 ARO:3000566 100 1.26e-264 1 373 1.0000 0.9443 tetracycline antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
IGLJDEHD_00001 2.A.1.2.38 100 3.5e-205 1 373 1.0000 0.9443 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)