Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C779
  Reference Plasmid   NZ_CP061323.1
  Reference Plasmid Size   127002
  Reference Plasmid GC Content   0.33
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0177499 FEGBNALF_00067 57667 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -571C>T None
M0177500 FEGBNALF_00068 58127 3 Gut 0.50 protein_coding synonymous_variant LOW 465C>A Ser155Ser
M0177501 FEGBNALF_00068 58142 3 Gut 0.50 protein_coding missense_variant MODERATE 450C>A His150Gln
M0177502 FEGBNALF_00068 58298 3 Gut 0.50 protein_coding synonymous_variant LOW 294G>A Leu98Leu
M0177503 FEGBNALF_00069 58800 3 Gut 0.50 protein_coding missense_variant MODERATE 100T>C Trp34Arg
M0177504 FEGBNALF_00069 58897 3 Gut 0.50 protein_coding synonymous_variant LOW 3G>T Val1Val
M0177505 FEGBNALF_00067 59059 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -1963A>G None
M0177506 FEGBNALF_00067 59152 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -2056T>C None
M0177507 FEGBNALF_00067 59328 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -2232A>G None
M0177508 FEGBNALF_00070 59398 3 Gut 0.50 protein_coding missense_variant MODERATE 1342G>A Val448Ile
M0177509 FEGBNALF_00070 59450 3 Gut 0.50 protein_coding synonymous_variant LOW 1290C>T Thr430Thr
M0177510 FEGBNALF_00070 59509 3 Gut 0.50 protein_coding missense_variant MODERATE 1231G>A Val411Ile
M0177511 FEGBNALF_00070 59729 3 Gut 0.50 protein_coding synonymous_variant LOW 1011G>T Val337Val
M0177512 FEGBNALF_00070 60060 3 Gut 0.50 protein_coding missense_variant MODERATE 680A>T Asp227Val
M0177513 FEGBNALF_00070 60473 3 Gut 0.50 protein_coding synonymous_variant LOW 267G>A Ala89Ala
M0177514 FEGBNALF_00070 60500 3 Gut 0.50 protein_coding synonymous_variant LOW 240A>G Leu80Leu
M0177515 FEGBNALF_00070 60532 3 Gut 0.50 protein_coding missense_variant MODERATE 208T>G Ser70Ala
M0177516 FEGBNALF_00070 60624 3 Gut 0.50 protein_coding missense_variant MODERATE 116T>G Leu39Arg
M0177517 FEGBNALF_00070 60628 3 Gut 0.50 protein_coding missense_variant MODERATE 112A>C Thr38Pro
M0177518 FEGBNALF_00070 60667 3 Gut 0.50 protein_coding missense_variant MODERATE 73T>G Ser25Ala
M0177519 FEGBNALF_00067 60747 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -3651A>G None
M0177520 FEGBNALF_00071 61018 3 Gut 0.50 protein_coding synonymous_variant LOW 483C>T Leu161Leu
M0177521 FEGBNALF_00071 61300 3 Gut 0.50 protein_coding synonymous_variant LOW 201C>T Asp67Asp
M0177522 FEGBNALF_00072 61541 3 Gut 0.50 protein_coding missense_variant MODERATE 226G>A Ala76Thr
M0177523 FEGBNALF_00072 61568 3 Gut 0.50 protein_coding missense_variant MODERATE 199C>G Arg67Gly
M0177524 FEGBNALF_00072 61615 3 Gut 0.50 protein_coding missense_variant MODERATE 152A>T Asp51Val
M0177525 FEGBNALF_00072 61616 3 Gut 0.50 protein_coding missense_variant MODERATE 151G>A Asp51Asn
M0177526 FEGBNALF_00072 61625 3 Gut 0.50 protein_coding missense_variant MODERATE 142A>C Thr48Pro
M0177527 FEGBNALF_00072 61647 3 Gut 0.50 protein_coding synonymous_variant LOW 120A>C Val40Val
M0177528 FEGBNALF_00072 61648 3 Gut 0.50 protein_coding missense_variant MODERATE 119T>C Val40Ala
M0177529 FEGBNALF_00072 61658 3 Gut 0.50 protein_coding missense_variant MODERATE 109C>A Leu37Ile
M0177530 FEGBNALF_00072 61730 3 Gut 0.50 protein_coding missense_variant MODERATE 37C>T Pro13Ser
M0177531 FEGBNALF_00072 61736 3 Gut 0.50 protein_coding missense_variant MODERATE 31C>T Pro11Ser
M0177532 FEGBNALF_00072 61757 3 Gut 0.50 protein_coding missense_variant MODERATE 10T>A Leu4Met
M0177533 FEGBNALF_00073 61791 3 Gut 0.50 protein_coding missense_variant MODERATE 551T>G Ile184Ser
M0177534 FEGBNALF_00073 61929 3 Gut 0.50 protein_coding missense_variant MODERATE 413G>C Gly138Ala
M0177535 FEGBNALF_00073 62135 3 Gut 0.50 protein_coding synonymous_variant LOW 207A>G Gly69Gly
M0177536 FEGBNALF_00073 62191 3 Gut 0.50 protein_coding missense_variant MODERATE 151T>A Cys51Ser
M0177537 FEGBNALF_00068 62366 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -3775A>T None
M0177538 FEGBNALF_00068 62367 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -3776A>T None
M0177539 FEGBNALF_00068 62438 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -3847G>A None
M0177540 FEGBNALF_00068 62445 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -3854C>T None
M0177541 FEGBNALF_00068 62483 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -3892A>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
FEGBNALF_00013 PHI:7637 CspA 75.8 4.8e-25 1 66 1.0000 1.0000 bony fishes listeriosis cold shock protein reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
FEGBNALF_00024 3.A.1.112.3 100 0 1 715 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
FEGBNALF_00026 1.C.22.1.1 100 5.7e-38 1 75 1.0000 1.0000 1 Channels/Pores 1.C Pore-Forming Toxins (Proteins and Peptides) 1.C.22 The Lactococcin A (Lactococcin A) Family
FEGBNALF_00028 1.C.22.1.2 100 3.7e-36 1 68 1.0000 1.0000 1 Channels/Pores 1.C Pore-Forming Toxins (Proteins and Peptides) 1.C.22 The Lactococcin A (Lactococcin A) Family
FEGBNALF_00064 2.A.7.21.4 99.7 1.1e-167 1 307 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.7 The Drug/Metabolite Transporter (DMT) Superfamily