Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C793
  Reference Plasmid   NZ_CP064305.1
  Reference Plasmid Size   71447
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0183685 DPEFOGGP_00023 16758 3 Gut 0.60 protein_coding splice_region_variant&stop_retained_variant LOW 137A>G Ter46Ter
M0183686 DPEFOGGP_00024 16871 3 Gut 0.60 protein_coding missense_variant MODERATE 91G>A Ala31Thr
M0183687 DPEFOGGP_00024 17054 3 Gut 0.60 protein_coding missense_variant MODERATE 274A>G Thr92Ala
M0183688 DPEFOGGP_00024 17059 3 Gut 0.60 protein_coding synonymous_variant LOW 279A>G Glu93Glu
M0183689 DPEFOGGP_00025 17510 3 Gut 0.60 protein_coding synonymous_variant LOW 357C>T Thr119Thr
M0183690 DPEFOGGP_00025 17514 3 Gut 0.60 protein_coding missense_variant MODERATE 361A>G Ile121Val
M0183691 DPEFOGGP_00025 17738 3 Gut 0.60 protein_coding synonymous_variant LOW 585A>G Glu195Glu
M0183692 DPEFOGGP_00025 17750 3 Gut 0.60 protein_coding synonymous_variant LOW 597G>A Arg199Arg
M0183693 DPEFOGGP_00025 17753 3 Gut 0.60 protein_coding synonymous_variant LOW 600A>G Leu200Leu
M0183694 DPEFOGGP_00025 17962 3 Gut 0.60 protein_coding missense_variant MODERATE 809A>T Gln270Leu
M0183695 DPEFOGGP_00025 18108 3 Gut 0.60 protein_coding missense_variant MODERATE 955G>A Val319Met
M0183696 DPEFOGGP_00025 18186 3 Gut 0.60 protein_coding missense_variant MODERATE 1033G>A Ala345Thr
M0183697 DPEFOGGP_00025 18205 3 Gut 0.60 protein_coding missense_variant MODERATE 1052T>A Val351Asp
M0183698 DPEFOGGP_00025 18263 3 Gut 0.60 protein_coding synonymous_variant LOW 1110G>A Leu370Leu
M0183699 DPEFOGGP_00025 18284 3 Gut 0.60 protein_coding synonymous_variant LOW 1131A>G Gln377Gln
M0183700 DPEFOGGP_00025 18479 3 Gut 0.60 protein_coding synonymous_variant LOW 1326A>G Glu442Glu
M0183701 DPEFOGGP_00025 18528 3 Gut 0.60 protein_coding missense_variant MODERATE 1375A>G Ile459Val
M0183702 DPEFOGGP_00025 18653 3 Gut 0.60 protein_coding missense_variant MODERATE 1500A>C Gln500His
M0183703 DPEFOGGP_00025 18662 3 Gut 0.60 protein_coding synonymous_variant LOW 1509A>C Thr503Thr
M0183704 DPEFOGGP_00025 18679 3 Gut 0.60 protein_coding missense_variant MODERATE 1526A>G His509Arg
M0183705 DPEFOGGP_00025 18764 3 Gut 0.60 protein_coding synonymous_variant LOW 1611C>T Pro537Pro
M0183706 DPEFOGGP_00025 18786 3 Gut 0.60 protein_coding missense_variant MODERATE 1633A>G Met545Val
M0183707 DPEFOGGP_00025 18798 3 Gut 0.60 protein_coding missense_variant MODERATE 1645A>T Arg549Trp
M0183708 DPEFOGGP_00025 18809 3 Gut 0.60 protein_coding synonymous_variant LOW 1656A>C Ala552Ala
M0183709 DPEFOGGP_00025 18812 3 Gut 0.60 protein_coding synonymous_variant LOW 1659C>T Asn553Asn
M0183710 DPEFOGGP_00025 18842 3 Gut 0.60 protein_coding synonymous_variant LOW 1689G>A Gln563Gln
M0183711 DPEFOGGP_00025 18851 3 Gut 0.60 protein_coding synonymous_variant LOW 1698A>G Val566Val
M0183712 DPEFOGGP_00025 18918 3 Gut 0.60 protein_coding missense_variant MODERATE 1765T>C Trp589Arg
M0183713 DPEFOGGP_00025 18938 3 Gut 0.60 protein_coding missense_variant MODERATE 1785T>A Asn595Lys
M0183714 DPEFOGGP_00025 18944 3 Gut 0.60 protein_coding synonymous_variant LOW 1791A>G Gln597Gln
M0183715 DPEFOGGP_00025 18959 3 Gut 0.60 protein_coding synonymous_variant LOW 1806A>G Gln602Gln
M0183716 DPEFOGGP_00025 18962 3 Gut 0.60 protein_coding synonymous_variant LOW 1809A>G Gln603Gln
M0183717 DPEFOGGP_00025 18994 3 Gut 0.60 protein_coding missense_variant MODERATE 1841A>G Asn614Ser
M0183718 DPEFOGGP_00025 19076 3 Gut 0.60 protein_coding missense_variant MODERATE 1923G>T Lys641Asn
M0183719 DPEFOGGP_00025 19088 3 Gut 0.60 protein_coding synonymous_variant LOW 1935A>G Arg645Arg
M0183720 DPEFOGGP_00025 19096 3 Gut 0.60 protein_coding missense_variant MODERATE 1943A>G Lys648Arg
M0183721 DPEFOGGP_00025 19115 3 Gut 0.60 protein_coding synonymous_variant LOW 1962T>A Ile654Ile
M0183722 DPEFOGGP_00025 19153 3 Gut 0.60 protein_coding missense_variant MODERATE 2000G>A Arg667Gln
M0183723 DPEFOGGP_00025 19166 3 Gut 0.60 protein_coding synonymous_variant LOW 2013G>A Pro671Pro
M0183724 DPEFOGGP_00025 19174 3 Gut 0.60 protein_coding missense_variant MODERATE 2021C>T Thr674Ile
M0183725 DPEFOGGP_00025 19199 3 Gut 0.60 protein_coding synonymous_variant LOW 2046T>C Ile682Ile
M0183726 DPEFOGGP_00025 19233 3 Gut 0.60 protein_coding missense_variant MODERATE 2080A>C Lys694Gln
M0183727 DPEFOGGP_00025 19235 3 Gut 0.60 protein_coding synonymous_variant LOW 2082G>A Lys694Lys
M0183728 DPEFOGGP_00025 19277 3 Gut 0.60 protein_coding synonymous_variant LOW 2124T>C Asp708Asp
M0183729 DPEFOGGP_00025 19286 3 Gut 0.60 protein_coding missense_variant MODERATE 2133C>A Asp711Glu
M0183730 DPEFOGGP_00025 19287 3 Gut 0.60 protein_coding synonymous_variant LOW 2134C>T Leu712Leu
M0183731 DPEFOGGP_00025 19293 3 Gut 0.60 protein_coding missense_variant MODERATE 2140G>A Asp714Asn
M0183732 DPEFOGGP_00025 19296 3 Gut 0.60 protein_coding missense_variant MODERATE 2143G>A Asp715Asn
M0183733 DPEFOGGP_00025 19314 3 Gut 0.60 protein_coding missense_variant MODERATE 2161C>T Pro721Ser
M0183734 DPEFOGGP_00025 19324 3 Gut 0.60 protein_coding missense_variant MODERATE 2171A>G Glu724Gly
M0183735 DPEFOGGP_00025 19331 3 Gut 0.60 protein_coding synonymous_variant LOW 2178G>A Glu726Glu
M0183736 DPEFOGGP_00026 19401 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -5T>C None
M0183737 DPEFOGGP_00026 19403 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -3A>G None
M0183738 DPEFOGGP_00026 19435 3 Gut 0.60 protein_coding synonymous_variant LOW 30C>T Ser10Ser
M0183739 DPEFOGGP_00026 19444 3 Gut 0.60 protein_coding synonymous_variant LOW 39A>G Thr13Thr
M0183740 DPEFOGGP_00026 19501 3 Gut 0.60 protein_coding synonymous_variant LOW 96A>C Ala32Ala
M0183741 DPEFOGGP_00026 19504 3 Gut 0.60 protein_coding synonymous_variant LOW 99G>A Leu33Leu
M0183742 DPEFOGGP_00026 19507 3 Gut 0.60 protein_coding synonymous_variant LOW 102A>G Val34Val
M0183743 DPEFOGGP_00026 19618 3 Gut 0.60 protein_coding synonymous_variant LOW 213C>T Asp71Asp
M0183744 DPEFOGGP_00026 19807 3 Gut 0.60 protein_coding synonymous_variant LOW 402G>A Gln134Gln
M0183745 DPEFOGGP_00026 20098 3 Gut 0.60 protein_coding synonymous_variant LOW 693A>G Leu231Leu
M0183746 DPEFOGGP_00026 20172 3 Gut 0.60 protein_coding missense_variant MODERATE 767C>G Ala256Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
DPEFOGGP_00016 QPC20408.1|GH73 100 0 1 818 1 0.9915
DPEFOGGP_00072 QPC20373.1|GH105 100 2.41e-202 1 268 1 0.9745





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
DPEFOGGP_00048 3.A.1.1.20 73 1.7e-162 1 366 0.9708 0.8492 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DPEFOGGP_00084 3.A.1.130.3 99.3 4.4e-155 1 287 1.0000 1.0913 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DPEFOGGP_00085 3.A.1.130.3 98.5 5.2e-137 14 276 0.9529 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily