Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C796
  Reference Plasmid   NZ_CP064408.1
  Reference Plasmid Size   62662
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0183763 CMCNHBKL_00002 2284 4 Gut 0.40 protein_coding synonymous_variant LOW 1191T>C Ile397Ile
M0183764 CMCNHBKL_00003 2726 4 Gut 0.40 protein_coding missense_variant MODERATE 17G>A Gly6Glu
M0183765 CMCNHBKL_00003 2952 4 Gut 0.40 protein_coding missense_variant MODERATE 243A>C Arg81Ser
M0183766 CMCNHBKL_00004 3233 4 Gut 0.40 protein_coding synonymous_variant LOW 72C>T Leu24Leu
M0183767 CMCNHBKL_00004 3258 4 Gut 0.40 protein_coding stop_lost&splice_region_variant HIGH 97T>C Ter33Glnext*?
M0183768 CMCNHBKL_00007 3377 4 Gut 0.40 protein_coding upstream_gene_variant MODIFIER -3415T>C None
M0183769 CMCNHBKL_00007 3619 4 Gut 0.40 protein_coding upstream_gene_variant MODIFIER -3173A>G None
M0183770 CMCNHBKL_00002 1050 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -44A>G None
M0183771 CMCNHBKL_00002 1159 3 Gut 0.30 protein_coding missense_variant MODERATE 66G>C Gln22His
M0183772 CMCNHBKL_00007 3271 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -3521G>T None
M0183773 CMCNHBKL_00007 3417 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -3375A>G None
M0183774 CMCNHBKL_00007 3512 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -3280T>G None
M0183775 CMCNHBKL_00007 3584 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -3208C>T None
M0183776 CMCNHBKL_00007 3617 3 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -3175C>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
CMCNHBKL_00027 VFG042994 Bee (biofilm enhancer in enterococci) 98.4 0 1 1085 1.0 1.0018 Adherence Bee1 prediction
CMCNHBKL_00028 VFG042995 Bee (biofilm enhancer in enterococci) 96.3 1.2e-129 1 243 1.0 1 Adherence Bee2 prediction
CMCNHBKL_00029 VFG042996 Bee (biofilm enhancer in enterococci) 97.3 8.1e-263 1 481 0.9796 0.9717 Adherence Bee3 prediction
CMCNHBKL_00030 VFG042997 Bee (biofilm enhancer in enterococci) 99.7 1.9e-225 1 398 1.0 1 Adherence Srt1 prediction
CMCNHBKL_00031 VFG042998 Bee (biofilm enhancer in enterococci) 99.5 4.3e-208 1 373 1.0 1 Adherence Srt2 prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
CMCNHBKL_00002 PHI:8586 mntH1 78.4 1.2e-222 21 530 0.9533 0.9586 moths nosocomial infection divalent metal cation transporter unaffected pathogenicity
CMCNHBKL_00042 PHI:5205 HMPREF0351_10118 (WxL locusC) 100 1e-226 1 392 1.0000 1.0000 rodents endocarditis involved in bile salt stress and endocarditis pathogenesis reduced virulence
CMCNHBKL_00060 PHI:5205 HMPREF0351_10118 (WxL locusC) 71.3 2.8e-165 1 389 1.0000 1.0000 rodents endocarditis involved in bile salt stress and endocarditis pathogenesis reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term