Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C800
  Reference Plasmid   NZ_CP065398.1
  Reference Plasmid Size   198121
  Reference Plasmid GC Content   0.57
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0183922 JHHDGJNJ_00138 117312 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4271G>A None
M0183923 JHHDGJNJ_00138 117711 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4670G>A None
M0183924 JHHDGJNJ_00143 119538 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4477C>T None
M0183925 JHHDGJNJ_00143 119749 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4688T>C None
M0183926 JHHDGJNJ_00143 119751 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4690T>A None
M0183927 JHHDGJNJ_00169 120471 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -1409C>T None
M0183928 JHHDGJNJ_00168 121232 3 Gut 0.16 protein_coding missense_variant MODERATE 92T>G Leu31Arg
M0183929 JHHDGJNJ_00167 121390 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -486C>T None
M0183930 JHHDGJNJ_00167 121818 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -914T>C None
M0183931 JHHDGJNJ_00167 121855 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -951A>G None
M0183932 JHHDGJNJ_00167 121859 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -955A>T None
M0183933 JHHDGJNJ_00169 122068 3 Gut 0.16 protein_coding synonymous_variant LOW 189G>C Val63Val
M0183934 JHHDGJNJ_00169 122074 3 Gut 0.16 protein_coding synonymous_variant LOW 195G>A Lys65Lys
M0183935 JHHDGJNJ_00169 122479 3 Gut 0.16 protein_coding synonymous_variant LOW 600C>T Phe200Phe
M0183936 JHHDGJNJ_00169 122482 3 Gut 0.16 protein_coding synonymous_variant LOW 603C>T Ile201Ile
M0183937 JHHDGJNJ_00169 122536 3 Gut 0.16 protein_coding synonymous_variant LOW 657C>T Thr219Thr
M0183938 JHHDGJNJ_00236 192555 3 Gut 0.16 protein_coding synonymous_variant LOW 666G>A Glu222Glu
M0183939 JHHDGJNJ_00236 192849 3 Gut 0.16 protein_coding synonymous_variant LOW 372T>C Tyr124Tyr
M0183940 JHHDGJNJ_00236 193031 3 Gut 0.16 protein_coding missense_variant MODERATE 190A>G Lys64Glu
M0183941 JHHDGJNJ_00236 193132 3 Gut 0.16 protein_coding missense_variant MODERATE 89G>A Arg30Gln
M0183942 JHHDGJNJ_00240 195947 3 Gut 0.16 protein_coding missense_variant MODERATE 588T>G Asn196Lys
M0183943 JHHDGJNJ_00240 196016 3 Gut 0.16 protein_coding synonymous_variant LOW 519T>C Asn173Asn
M0183944 JHHDGJNJ_00240 196423 3 Gut 0.16 protein_coding missense_variant MODERATE 112A>G Ser38Gly
M0183945 JHHDGJNJ_00240 196493 3 Gut 0.16 protein_coding synonymous_variant LOW 42T>C Phe14Phe
M0183946 JHHDGJNJ_00240 196507 3 Gut 0.16 protein_coding missense_variant MODERATE 28T>G Ser10Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term