Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C801
  Reference Plasmid   NZ_CP065610.1
  Reference Plasmid Size   97745
  Reference Plasmid GC Content   0.52
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0183947 ALNPMOHC_00093 77474 3 Gut 0.18 protein_coding missense_variant MODERATE 1174G>A Val392Met
M0183948 ALNPMOHC_00065 58077 3 Gut 0.18 protein_coding synonymous_variant LOW 4443G>A Ala1481Ala
M0183949 ALNPMOHC_00065 58078 3 Gut 0.18 protein_coding missense_variant MODERATE 4444C>G Gln1482Glu
M0183950 ALNPMOHC_00065 58137 3 Gut 0.18 protein_coding synonymous_variant LOW 4503T>C Leu1501Leu
M0183951 ALNPMOHC_00065 58152 3 Gut 0.18 protein_coding synonymous_variant LOW 4518T>G Leu1506Leu
M0183952 ALNPMOHC_00065 58185 3 Gut 0.18 protein_coding synonymous_variant LOW 4551A>T Ala1517Ala
M0183953 ALNPMOHC_00065 58191 3 Gut 0.18 protein_coding synonymous_variant LOW 4557G>A Gly1519Gly
M0183954 ALNPMOHC_00065 58194 3 Gut 0.18 protein_coding synonymous_variant LOW 4560C>T Arg1520Arg
M0183955 ALNPMOHC_00065 58206 3 Gut 0.18 protein_coding synonymous_variant LOW 4572G>A Gln1524Gln
M0183956 ALNPMOHC_00065 58244 3 Gut 0.18 protein_coding missense_variant MODERATE 4610G>A Arg1537Lys
M0183957 ALNPMOHC_00065 58248 3 Gut 0.18 protein_coding synonymous_variant LOW 4614A>C Ser1538Ser
M0183958 ALNPMOHC_00065 58251 3 Gut 0.18 protein_coding synonymous_variant LOW 4617A>C Ala1539Ala
M0183959 ALNPMOHC_00065 58269 3 Gut 0.18 protein_coding synonymous_variant LOW 4635A>G Pro1545Pro
M0183960 ALNPMOHC_00065 58308 3 Gut 0.18 protein_coding synonymous_variant LOW 4674T>C Ser1558Ser
M0183961 ALNPMOHC_00065 58317 3 Gut 0.18 protein_coding synonymous_variant LOW 4683A>T Gly1561Gly
M0183962 ALNPMOHC_00065 58323 3 Gut 0.18 protein_coding synonymous_variant LOW 4689G>A Val1563Val
M0183963 ALNPMOHC_00065 58332 3 Gut 0.18 protein_coding synonymous_variant LOW 4698T>C Ser1566Ser
M0183964 ALNPMOHC_00065 58334 3 Gut 0.18 protein_coding missense_variant MODERATE 4700A>G Glu1567Gly
M0183965 ALNPMOHC_00065 58335 3 Gut 0.18 protein_coding synonymous_variant LOW 4701A>G Glu1567Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
ALNPMOHC_00031 AKO58984.1|GH23 100 1.73e-124 1 169 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term