Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C806
  Reference Plasmid   NZ_CP065894.1
  Reference Plasmid Size   225058
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0101970 PCMONPGO_00159 180677 3 Skin 0.04 protein_coding missense_variant MODERATE 373T>C Cys125Arg
M0101971 PCMONPGO_00159 180722 3 Skin 0.04 protein_coding missense_variant MODERATE 328G>T Ala110Ser
M0101972 PCMONPGO_00159 180739 3 Skin 0.04 protein_coding missense_variant MODERATE 311A>C Lys104Thr
M0101973 PCMONPGO_00159 180740 3 Skin 0.04 protein_coding missense_variant MODERATE 310A>G Lys104Glu
M0101974 PCMONPGO_00159 180741 3 Skin 0.04 protein_coding synonymous_variant LOW 309T>C Cys103Cys
M0101975 PCMONPGO_00159 180945 3 Skin 0.04 protein_coding synonymous_variant LOW 105C>T Ala35Ala
M0101976 PCMONPGO_00011 11547 3 Skin 0.04 protein_coding synonymous_variant LOW 1134T>G Arg378Arg
M0101977 PCMONPGO_00011 11559 3 Skin 0.04 protein_coding synonymous_variant LOW 1146G>A Ala382Ala
M0101978 PCMONPGO_00131 139674 3 Skin 0.04 protein_coding synonymous_variant LOW 193T>C Leu65Leu
M0101979 PCMONPGO_00131 139708 3 Skin 0.04 protein_coding synonymous_variant LOW 159T>C Gly53Gly
M0101980 PCMONPGO_00131 139711 3 Skin 0.04 protein_coding synonymous_variant LOW 156T>C Phe52Phe
M0101981 PCMONPGO_00158 179012 3 Skin 0.04 protein_coding synonymous_variant LOW 27C>G Thr9Thr
M0101982 PCMONPGO_00159 179091 3 Skin 0.04 protein_coding synonymous_variant LOW 1959T>C Ala653Ala
M0101983 PCMONPGO_00159 179133 3 Skin 0.04 protein_coding synonymous_variant LOW 1917C>T His639His
M0101984 PCMONPGO_00159 179178 3 Skin 0.04 protein_coding synonymous_variant LOW 1872T>C Ser624Ser
M0101985 PCMONPGO_00159 179184 3 Skin 0.04 protein_coding synonymous_variant LOW 1866A>G Ala622Ala
M0101986 PCMONPGO_00159 179337 3 Skin 0.04 protein_coding synonymous_variant LOW 1713A>G Ala571Ala
M0101987 PCMONPGO_00159 179386 3 Skin 0.04 protein_coding missense_variant MODERATE 1664T>C Val555Ala
M0101988 PCMONPGO_00159 179484 3 Skin 0.04 protein_coding synonymous_variant LOW 1566T>C Asp522Asp
M0101989 PCMONPGO_00159 179502 3 Skin 0.04 protein_coding synonymous_variant LOW 1548A>G Leu516Leu
M0101990 PCMONPGO_00145 163613 3 Skin 0.04 protein_coding missense_variant MODERATE 920G>A Arg307Gln
M0101991 PCMONPGO_00145 163716 3 Skin 0.04 protein_coding synonymous_variant LOW 1023T>C Val341Val
M0101992 PCMONPGO_00145 163779 3 Skin 0.04 protein_coding synonymous_variant LOW 1086T>C Ile362Ile
M0101993 PCMONPGO_00145 163854 3 Skin 0.04 protein_coding synonymous_variant LOW 1161G>A Arg387Arg
M0101994 PCMONPGO_00109 109109 3 Skin 0.04 protein_coding synonymous_variant LOW 340T>C Leu114Leu
M0101995 PCMONPGO_00109 109151 3 Skin 0.04 protein_coding missense_variant MODERATE 298G>C Ala100Pro
M0101996 PCMONPGO_00109 109154 3 Skin 0.04 protein_coding missense_variant MODERATE 295G>T Ala99Ser
M0101997 PCMONPGO_00109 109166 3 Skin 0.04 protein_coding missense_variant MODERATE 283A>G Ile95Val
M0101998 PCMONPGO_00109 109233 3 Skin 0.04 protein_coding synonymous_variant LOW 216C>G Ser72Ser
M0101999 PCMONPGO_00110 110109 3 Skin 0.04 protein_coding synonymous_variant LOW 207A>G Ala69Ala
M0102000 PCMONPGO_00110 110115 3 Skin 0.04 protein_coding synonymous_variant LOW 201T>C Pro67Pro
M0102001 PCMONPGO_00110 110253 3 Skin 0.04 protein_coding synonymous_variant LOW 63A>G Ala21Ala
M0102002 PCMONPGO_00193 217123 3 Skin 0.04 protein_coding synonymous_variant LOW 538T>C Leu180Leu
M0102003 PCMONPGO_00193 217221 3 Skin 0.04 protein_coding synonymous_variant LOW 636C>G Leu212Leu
M0102004 PCMONPGO_00193 217233 3 Skin 0.04 protein_coding synonymous_variant LOW 648T>G Arg216Arg
M0102005 PCMONPGO_00007 7917 3 Skin 0.04 protein_coding synonymous_variant LOW 1167C>A Gly389Gly
M0102006 PCMONPGO_00007 7938 3 Skin 0.04 protein_coding synonymous_variant LOW 1188T>C Arg396Arg
M0102007 PCMONPGO_00007 7956 3 Skin 0.04 protein_coding synonymous_variant LOW 1206T>C Ile402Ile
M0102008 PCMONPGO_00007 8142 3 Skin 0.04 protein_coding synonymous_variant LOW 1392A>G Ala464Ala
M0102009 PCMONPGO_00184 210516 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -3933C>G None
M0102010 PCMONPGO_00189 210553 3 Skin 0.04 protein_coding synonymous_variant LOW 981C>T Ala327Ala
M0102011 PCMONPGO_00189 210645 3 Skin 0.04 protein_coding missense_variant MODERATE 889A>G Thr297Ala
M0102012 PCMONPGO_00189 210814 3 Skin 0.04 protein_coding synonymous_variant LOW 720T>C Arg240Arg
M0102013 PCMONPGO_00189 210900 3 Skin 0.04 protein_coding missense_variant MODERATE 634A>G Thr212Ala
M0102014 PCMONPGO_00189 211033 3 Skin 0.04 protein_coding synonymous_variant LOW 501C>G Ala167Ala
M0102015 PCMONPGO_00189 211092 3 Skin 0.04 protein_coding synonymous_variant LOW 442A>C Arg148Arg
M0102016 PCMONPGO_00189 211504 3 Skin 0.04 protein_coding synonymous_variant LOW 30A>C Thr10Thr
M0102017 PCMONPGO_00189 211519 3 Skin 0.04 protein_coding synonymous_variant LOW 15T>C Arg5Arg
M0102018 PCMONPGO_00184 211558 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -4975C>G None
M0102019 PCMONPGO_00190 211679 3 Skin 0.04 protein_coding missense_variant MODERATE 22T>C Phe8Leu
M0102020 PCMONPGO_00190 211720 3 Skin 0.04 protein_coding synonymous_variant LOW 63A>C Gly21Gly
M0102021 PCMONPGO_00002 2073 3 Skin 0.04 protein_coding synonymous_variant LOW 936T>C Gly312Gly
M0102022 PCMONPGO_00136 150417 3 Skin 0.04 protein_coding synonymous_variant LOW 5640C>G Ala1880Ala
M0102023 PCMONPGO_00136 150525 3 Skin 0.04 protein_coding synonymous_variant LOW 5748C>G Ala1916Ala
M0102024 PCMONPGO_00136 150553 3 Skin 0.04 protein_coding synonymous_variant LOW 5776T>C Leu1926Leu
M0102025 PCMONPGO_00009 9383 3 Skin 0.04 protein_coding synonymous_variant LOW 651T>C Thr217Thr
M0102026 PCMONPGO_00009 9393 3 Skin 0.04 protein_coding synonymous_variant LOW 661T>C Leu221Leu
M0102027 PCMONPGO_00010 9518 3 Skin 0.04 protein_coding missense_variant MODERATE 691G>C Gly231Arg
M0102028 PCMONPGO_00010 9651 3 Skin 0.04 protein_coding synonymous_variant LOW 558G>A Gln186Gln
M0102029 PCMONPGO_00004 4095 3 Skin 0.04 protein_coding missense_variant MODERATE 364A>G Arg122Gly
M0102030 PCMONPGO_00004 4247 3 Skin 0.04 protein_coding synonymous_variant LOW 516A>G Ala172Ala
M0102031 PCMONPGO_00004 4529 3 Skin 0.04 protein_coding synonymous_variant LOW 798G>C Val266Val
M0102032 PCMONPGO_00004 4570 3 Skin 0.04 protein_coding missense_variant MODERATE 839C>G Ala280Gly
M0102033 PCMONPGO_00004 4571 3 Skin 0.04 protein_coding synonymous_variant LOW 840G>C Ala280Ala
M0102034 PCMONPGO_00004 4625 3 Skin 0.04 protein_coding synonymous_variant LOW 894T>G Leu298Leu
M0102035 PCMONPGO_00005 4712 3 Skin 0.04 protein_coding synonymous_variant LOW 603G>C Gly201Gly
M0102036 PCMONPGO_00005 5054 3 Skin 0.04 protein_coding synonymous_variant LOW 261T>C Ser87Ser
M0102037 PCMONPGO_00005 5063 3 Skin 0.04 protein_coding synonymous_variant LOW 252A>G Glu84Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
PCMONPGO_00017 QXI65566.1|CBM48|GH13_10 100 0 1 560 1 1
PCMONPGO_00018 QXI65567.1|GH13_26 100 0 1 747 1 1
PCMONPGO_00020 QXI65569.1|CBM48|GH13_11 100 0 1 680 1 1
PCMONPGO_00056 QXI65605.1|GH36 100 0 1 680 1 1
PCMONPGO_00065 QXI65614.1|GH2 100 0 1 443 1 1
PCMONPGO_00127 QXI65676.1|GT4 100 1.64e-297 1 414 1 1
PCMONPGO_00129 QXI65678.1|GT26 100 2.13e-175 1 252 1 1
PCMONPGO_00130 QXI65679.1|GT4 100 9.5e-281 1 387 1 1
PCMONPGO_00137 QXI65686.1|GT2 100 9.93e-238 1 325 1 1
PCMONPGO_00140 QXI65689.1|GT2 100 4.06e-240 1 331 1 1
PCMONPGO_00144 QXI65693.1|GT4 100 9.47e-279 1 392 1 1
PCMONPGO_00145 QXI65694.1|GT4 100 3.95e-309 1 422 1 1
PCMONPGO_00147 QXI65696.1|GT2 100 5.11e-201 1 279 1 1
PCMONPGO_00156 QXI65705.1|GT4 100 2.19e-291 1 388 1 1
PCMONPGO_00157 QXI65706.1|GT2 100 1.95e-247 1 322 1 1
PCMONPGO_00158 QXI65707.1|GT0 100 9.28e-292 1 386 1 1
PCMONPGO_00159 QXI65708.1|GT4 100 0 1 672 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
PCMONPGO_00034 3.A.1.1.35 71.3 5.1e-256 5 567 0.9929 0.9982 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily