Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C810
  Reference Plasmid   NZ_CP066373.1
  Reference Plasmid Size   28218
  Reference Plasmid GC Content   0.30
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0102042 ENNMJDDN_00020 19691 4 Skin 0.11 protein_coding missense_variant MODERATE 646C>A Leu216Ile
M0102043 ENNMJDDN_00020 19849 3 Skin 0.08 protein_coding missense_variant MODERATE 488C>A Ala163Glu
M0102044 ENNMJDDN_00020 19971 4 Skin 0.11 protein_coding missense_variant MODERATE 366A>C Lys122Asn
M0102045 ENNMJDDN_00020 19984 5 Skin 0.14 protein_coding missense_variant MODERATE 353T>C Ile118Thr
M0102046 ENNMJDDN_00020 20244 3 Skin 0.08 protein_coding synonymous_variant LOW 93G>A Ser31Ser
M0102047 ENNMJDDN_00020 20284 5 Skin 0.14 protein_coding missense_variant MODERATE 53A>G Asn18Ser
M0102048 ENNMJDDN_00016 20337 5 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -1861A>T None
M0102049 ENNMJDDN_00016 20338 5 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -1862C>T None
M0102050 ENNMJDDN_00016 20342 5 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -1866G>A None
M0102051 ENNMJDDN_00016 20349 5 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -1873G>A None
M0102052 ENNMJDDN_00016 20351 5 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -1875C>A None
M0102053 ENNMJDDN_00016 20435 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -1959A>T None
M0102054 ENNMJDDN_00016 20439 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -1963G>T None
M0102055 ENNMJDDN_00021 20457 3 Skin 0.08 protein_coding missense_variant MODERATE 4A>C Lys2Gln
M0102056 ENNMJDDN_00021 20463 3 Skin 0.08 protein_coding missense_variant MODERATE 10A>G Lys4Glu
M0102057 ENNMJDDN_00021 20468 3 Skin 0.08 protein_coding synonymous_variant LOW 15T>C Tyr5Tyr
M0102058 ENNMJDDN_00021 20483 3 Skin 0.08 protein_coding synonymous_variant LOW 30C>T Ile10Ile
M0102059 ENNMJDDN_00021 20486 3 Skin 0.08 protein_coding synonymous_variant LOW 33C>T Ile11Ile
M0102060 ENNMJDDN_00021 20504 3 Skin 0.08 protein_coding synonymous_variant LOW 51C>T Ile17Ile
M0102061 ENNMJDDN_00021 20505 3 Skin 0.08 protein_coding missense_variant MODERATE 52G>T Val18Phe
M0102062 ENNMJDDN_00021 20534 3 Skin 0.08 protein_coding synonymous_variant LOW 81C>T His27His
M0102063 ENNMJDDN_00021 20634 6 Skin 0.16 protein_coding missense_variant MODERATE 181C>A Gln61Lys
M0102064 ENNMJDDN_00021 20575 3 Skin 0.08 protein_coding missense_variant MODERATE 122G>A Arg41Lys
M0102065 ENNMJDDN_00020 23487 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -3151G>A None
M0102066 ENNMJDDN_00024 23779 3 Skin 0.08 protein_coding missense_variant MODERATE 94G>A Asp32Asn
M0102067 ENNMJDDN_00020 23896 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -3560G>T None
M0102068 ENNMJDDN_00020 24034 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -3698C>A None
M0102069 ENNMJDDN_00020 24135 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -3799A>G None
M0102070 ENNMJDDN_00025 24617 4 Skin 0.11 protein_coding missense_variant MODERATE 316A>C Lys106Gln
M0102071 ENNMJDDN_00004 5520 7 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -171T>C None
M0102072 ENNMJDDN_00005 7952 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -186A>C None
M0102073 ENNMJDDN_00006 8966 3 Skin 0.08 protein_coding synonymous_variant LOW 705C>T Ile235Ile
M0102074 ENNMJDDN_00006 8968 3 Skin 0.08 protein_coding missense_variant MODERATE 707G>A Arg236Lys
M0102075 ENNMJDDN_00006 9029 3 Skin 0.08 protein_coding missense_variant MODERATE 768A>T Leu256Phe
M0102076 ENNMJDDN_00004 5414 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -277A>C None
M0102077 ENNMJDDN_00004 5641 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -50A>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term