Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C822
  Reference Plasmid   NZ_CP068111.1
  Reference Plasmid Size   54921
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0103597 GGPIMCCM_00019 18880 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -2552C>A None
M0103598 GGPIMCCM_00019 19476 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -3148T>C None
M0103599 GGPIMCCM_00023 19595 3 Skin 0.11 protein_coding missense_variant MODERATE 55T>A Leu19Met
M0103600 GGPIMCCM_00023 19753 4 Skin 0.14 protein_coding synonymous_variant LOW 213T>C Cys71Cys
M0103601 GGPIMCCM_00024 19868 5 Skin 0.18 protein_coding synonymous_variant LOW 30T>C Thr10Thr
M0103602 GGPIMCCM_00024 19931 3 Skin 0.11 protein_coding synonymous_variant LOW 93T>A Ala31Ala
M0103603 GGPIMCCM_00024 20024 4 Skin 0.14 protein_coding synonymous_variant LOW 186C>T Asp62Asp
M0103604 GGPIMCCM_00024 20066 5 Skin 0.18 protein_coding synonymous_variant LOW 228A>G Lys76Lys
M0103605 GGPIMCCM_00024 20313 3 Skin 0.11 protein_coding missense_variant MODERATE 475G>A Glu159Lys
M0103606 GGPIMCCM_00025 20920 4 Skin 0.14 protein_coding missense_variant MODERATE 326T>C Val109Ala
M0103607 GGPIMCCM_00025 20930 4 Skin 0.14 protein_coding missense_variant MODERATE 336C>A His112Gln
M0103608 GGPIMCCM_00018 14998 3 Skin 0.11 protein_coding synonymous_variant LOW 186T>C Ala62Ala
M0103609 GGPIMCCM_00018 15088 3 Skin 0.11 protein_coding synonymous_variant LOW 276G>C Ala92Ala
M0103610 GGPIMCCM_00022 15123 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -3922T>C None
M0103611 GGPIMCCM_00022 15296 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -3749C>T None
M0103612 GGPIMCCM_00019 15778 3 Skin 0.11 protein_coding missense_variant MODERATE 551C>T Thr184Ile
M0103613 GGPIMCCM_00019 15803 3 Skin 0.11 protein_coding missense_variant MODERATE 526C>A His176Asn
M0103614 GGPIMCCM_00020 17257 3 Skin 0.11 protein_coding missense_variant MODERATE 728T>C Val243Ala
M0103615 GGPIMCCM_00021 18237 5 Skin 0.18 protein_coding missense_variant MODERATE 484C>T Leu162Phe
M0103616 GGPIMCCM_00021 18328 3 Skin 0.11 protein_coding missense_variant MODERATE 393G>A Met131Ile
M0103617 GGPIMCCM_00021 18601 4 Skin 0.14 protein_coding synonymous_variant LOW 120G>A Leu40Leu
M0103618 GGPIMCCM_00019 18800 4 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -2472T>C None
M0103619 GGPIMCCM_00019 18911 4 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -2583G>A None
M0103620 GGPIMCCM_00019 19385 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -3057C>T None
M0103621 GGPIMCCM_00023 19681 3 Skin 0.11 protein_coding synonymous_variant LOW 141T>C Asp47Asp
M0103622 GGPIMCCM_00023 19696 3 Skin 0.11 protein_coding synonymous_variant LOW 156T>C Ala52Ala
M0103623 GGPIMCCM_00023 19705 4 Skin 0.14 protein_coding synonymous_variant LOW 165A>G Ala55Ala
M0103624 GGPIMCCM_00024 19891 3 Skin 0.11 protein_coding missense_variant MODERATE 53T>C Val18Ala
M0103625 GGPIMCCM_00024 20185 3 Skin 0.11 protein_coding missense_variant MODERATE 347C>A Ala116Glu
M0103626 GGPIMCCM_00024 20186 3 Skin 0.11 protein_coding synonymous_variant LOW 348G>A Ala116Ala
M0103627 GGPIMCCM_00024 20234 3 Skin 0.11 protein_coding synonymous_variant LOW 396T>A Ala132Ala
M0103628 GGPIMCCM_00024 20237 3 Skin 0.11 protein_coding synonymous_variant LOW 399G>T Ser133Ser
M0103629 GGPIMCCM_00047 43446 3 Skin 0.11 protein_coding missense_variant MODERATE 448A>G Lys150Glu
M0103630 GGPIMCCM_00047 43667 3 Skin 0.11 protein_coding missense_variant MODERATE 669T>G Ile223Met
M0103631 GGPIMCCM_00047 43670 3 Skin 0.11 protein_coding synonymous_variant LOW 672T>G Gly224Gly
M0103632 GGPIMCCM_00047 43734 3 Skin 0.11 protein_coding synonymous_variant LOW 736C>T Leu246Leu
M0103633 GGPIMCCM_00047 43736 3 Skin 0.11 protein_coding synonymous_variant LOW 738G>A Leu246Leu
M0103634 GGPIMCCM_00047 43805 3 Skin 0.11 protein_coding synonymous_variant LOW 807T>C Arg269Arg
M0103635 GGPIMCCM_00047 43808 3 Skin 0.11 protein_coding synonymous_variant LOW 810C>T Tyr270Tyr
M0103636 GGPIMCCM_00047 43877 3 Skin 0.11 protein_coding synonymous_variant LOW 879C>T Ile293Ile
M0103637 GGPIMCCM_00048 44569 3 Skin 0.11 protein_coding synonymous_variant LOW 381G>A Leu127Leu
M0103638 GGPIMCCM_00048 44574 3 Skin 0.11 protein_coding missense_variant MODERATE 386A>G Asn129Ser
M0103639 GGPIMCCM_00048 44581 3 Skin 0.11 protein_coding synonymous_variant LOW 393C>T Ser131Ser
M0103640 GGPIMCCM_00048 44585 3 Skin 0.11 protein_coding missense_variant MODERATE 397G>T Ala133Ser
M0103641 GGPIMCCM_00048 44587 3 Skin 0.11 protein_coding synonymous_variant LOW 399T>A Ala133Ala
M0103642 GGPIMCCM_00048 44606 3 Skin 0.11 protein_coding missense_variant MODERATE 418C>A Leu140Ile
M0103643 GGPIMCCM_00048 44713 3 Skin 0.11 protein_coding synonymous_variant LOW 525G>A Lys175Lys
M0103644 GGPIMCCM_00048 44820 3 Skin 0.11 protein_coding missense_variant MODERATE 632C>T Thr211Ile
M0103645 GGPIMCCM_00048 44827 3 Skin 0.11 protein_coding missense_variant MODERATE 639A>C Glu213Asp
M0103646 GGPIMCCM_00048 44834 3 Skin 0.11 protein_coding missense_variant MODERATE 646A>G Thr216Ala
M0103647 GGPIMCCM_00049 46272 3 Skin 0.11 protein_coding synonymous_variant LOW 318T>C Gly106Gly
M0103648 GGPIMCCM_00049 47034 3 Skin 0.11 protein_coding synonymous_variant LOW 1080G>A Gly360Gly
M0103649 GGPIMCCM_00032 29593 4 Skin 0.14 protein_coding missense_variant MODERATE 59T>C Ile20Thr
M0103650 GGPIMCCM_00033 30274 7 Skin 0.25 protein_coding missense_variant MODERATE 445G>A Val149Ile
M0103651 GGPIMCCM_00020 17657 4 Skin 0.14 protein_coding missense_variant MODERATE 328A>G Asn110Asp
M0103652 GGPIMCCM_00032 29538 3 Skin 0.11 protein_coding synonymous_variant LOW 114A>G Lys38Lys
M0103653 GGPIMCCM_00031 30949 5 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -1761A>G None
M0103654 GGPIMCCM_00031 30967 5 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -1779C>A None
M0103655 GGPIMCCM_00031 31046 5 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -1858T>A None
M0103656 GGPIMCCM_00031 31051 5 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -1863G>A None
M0103657 GGPIMCCM_00031 31074 5 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -1886T>C None
M0103658 GGPIMCCM_00035 31160 6 Skin 0.21 protein_coding synonymous_variant LOW 78T>C Val26Val
M0103659 GGPIMCCM_00035 31229 5 Skin 0.18 protein_coding missense_variant MODERATE 147C>A Asp49Glu
M0103660 GGPIMCCM_00033 30210 3 Skin 0.11 protein_coding synonymous_variant LOW 381C>T Phe127Phe






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term