Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C850
  Reference Plasmid   NZ_CP070058.1
  Reference Plasmid Size   22180
  Reference Plasmid GC Content   0.27
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0104319 CCEDOCHD_00001 301 8 Skin 0.20 protein_coding missense_variant MODERATE 6G>T Lys2Asn
M0104320 CCEDOCHD_00009 9430 4 Skin 0.10 protein_coding missense_variant MODERATE 1255C>T Leu419Phe
M0104321 CCEDOCHD_00009 9950 3 Skin 0.08 protein_coding synonymous_variant LOW 735A>T Thr245Thr
M0104322 CCEDOCHD_00009 10073 4 Skin 0.10 protein_coding synonymous_variant LOW 612T>C Phe204Phe
M0104323 CCEDOCHD_00009 10188 4 Skin 0.10 protein_coding missense_variant MODERATE 497A>C Asp166Ala
M0104324 CCEDOCHD_00009 10478 10 Skin 0.25 protein_coding synonymous_variant LOW 207T>C Thr69Thr
M0104325 CCEDOCHD_00009 10480 7 Skin 0.18 protein_coding missense_variant MODERATE 205A>G Thr69Ala
M0104326 CCEDOCHD_00003 4704 4 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -2097A>C None
M0104327 CCEDOCHD_00005 3883 3 Skin 0.08 protein_coding synonymous_variant LOW 168T>C Asn56Asn
M0104328 CCEDOCHD_00005 4069 3 Skin 0.08 protein_coding synonymous_variant LOW 354G>A Ser118Ser
M0104329 CCEDOCHD_00005 4123 3 Skin 0.08 protein_coding synonymous_variant LOW 408C>T Asn136Asn
M0104330 CCEDOCHD_00005 4138 3 Skin 0.08 protein_coding synonymous_variant LOW 423T>C Ile141Ile
M0104331 CCEDOCHD_00005 4220 3 Skin 0.08 protein_coding missense_variant MODERATE 505A>C Lys169Gln
M0104332 CCEDOCHD_00003 4473 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -1866T>G None
M0104333 CCEDOCHD_00006 4498 3 Skin 0.08 protein_coding missense_variant MODERATE 107C>T Ser36Leu
M0104334 CCEDOCHD_00006 4571 3 Skin 0.08 protein_coding missense_variant MODERATE 34C>A Gln12Lys
M0104335 CCEDOCHD_00003 4664 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2057A>G None
M0104336 CCEDOCHD_00003 4807 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2200T>C None
M0104337 CCEDOCHD_00003 5129 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2522T>C None
M0104338 CCEDOCHD_00003 5132 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2525G>A None
M0104339 CCEDOCHD_00003 5134 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2527T>G None
M0104340 CCEDOCHD_00003 5165 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2558C>T None
M0104341 CCEDOCHD_00022 20933 4 Skin 0.10 protein_coding synonymous_variant LOW 348G>A Glu116Glu
M0104342 CCEDOCHD_00017 21411 6 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4920C>T None
M0104343 CCEDOCHD_00023 21591 5 Skin 0.13 protein_coding synonymous_variant LOW 180C>T Phe60Phe
M0104344 CCEDOCHD_00010 10780 3 Skin 0.08 protein_coding missense_variant MODERATE 28A>G Ile10Val
M0104345 CCEDOCHD_00007 6688 4 Skin 0.10 protein_coding synonymous_variant LOW 1512A>G Arg504Arg
M0104346 CCEDOCHD_00007 6726 4 Skin 0.10 protein_coding missense_variant MODERATE 1474A>G Asn492Asp
M0104347 CCEDOCHD_00007 6942 4 Skin 0.10 protein_coding missense_variant MODERATE 1258G>A Val420Ile
M0104348 CCEDOCHD_00007 7225 4 Skin 0.10 protein_coding synonymous_variant LOW 975T>G Gly325Gly
M0104349 CCEDOCHD_00007 7299 4 Skin 0.10 protein_coding missense_variant MODERATE 901G>T Ala301Ser
M0104350 CCEDOCHD_00007 7547 4 Skin 0.10 protein_coding missense_variant MODERATE 653G>A Cys218Tyr
M0104351 CCEDOCHD_00007 7771 3 Skin 0.08 protein_coding synonymous_variant LOW 429G>A Lys143Lys
M0104352 CCEDOCHD_00007 7847 3 Skin 0.08 protein_coding missense_variant MODERATE 353T>A Leu118Gln
M0104353 CCEDOCHD_00007 7947 3 Skin 0.08 protein_coding missense_variant MODERATE 253C>A Gln85Lys
M0104354 CCEDOCHD_00007 8114 4 Skin 0.10 protein_coding missense_variant MODERATE 86C>G Ala29Gly
M0104355 CCEDOCHD_00004 8386 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -4724T>C None
M0104356 CCEDOCHD_00004 8464 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -4802A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term