Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C862
  Reference Plasmid   NZ_CP071515.1
  Reference Plasmid Size   3856
  Reference Plasmid GC Content   0.31
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0104477 KGOANKCA_00001 280 3 Skin 0.25 protein_coding missense_variant MODERATE 464G>C Ser155Thr
M0104478 KGOANKCA_00002 1538 7 Skin 0.58 protein_coding synonymous_variant LOW 300C>T Asn100Asn
M0104479 KGOANKCA_00001 1837 6 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1094A>G None
M0104480 KGOANKCA_00003 2182 6 Skin 0.50 protein_coding missense_variant MODERATE 77T>C Ile26Thr
M0104481 KGOANKCA_00003 2219 4 Skin 0.33 protein_coding synonymous_variant LOW 114C>T Asn38Asn
M0104482 KGOANKCA_00003 2222 4 Skin 0.33 protein_coding synonymous_variant LOW 117T>C Tyr39Tyr
M0104483 KGOANKCA_00003 2234 5 Skin 0.42 protein_coding synonymous_variant LOW 129C>T Asp43Asp
M0104484 KGOANKCA_00003 2372 4 Skin 0.33 protein_coding synonymous_variant LOW 267T>C Val89Val
M0104485 KGOANKCA_00003 2381 4 Skin 0.33 protein_coding synonymous_variant LOW 276C>T Ile92Ile
M0104486 KGOANKCA_00003 2411 4 Skin 0.33 protein_coding synonymous_variant LOW 306G>A Gly102Gly
M0104487 KGOANKCA_00003 2434 4 Skin 0.33 protein_coding missense_variant MODERATE 329A>G Gln110Arg
M0104488 KGOANKCA_00003 2465 5 Skin 0.42 protein_coding synonymous_variant LOW 360C>T Cys120Cys
M0104489 KGOANKCA_00003 2504 4 Skin 0.33 protein_coding synonymous_variant LOW 399T>C Val133Val
M0104490 KGOANKCA_00003 2582 3 Skin 0.25 protein_coding synonymous_variant LOW 477G>A Glu159Glu
M0104491 KGOANKCA_00003 2918 3 Skin 0.25 protein_coding synonymous_variant LOW 813G>A Glu271Glu
M0104492 KGOANKCA_00003 2936 3 Skin 0.25 protein_coding synonymous_variant LOW 831C>T Asn277Asn
M0104493 KGOANKCA_00003 2943 3 Skin 0.25 protein_coding missense_variant MODERATE 838A>G Thr280Ala
M0104494 KGOANKCA_00003 2945 3 Skin 0.25 protein_coding synonymous_variant LOW 840T>A Thr280Thr
M0104495 KGOANKCA_00003 2961 3 Skin 0.25 protein_coding missense_variant MODERATE 856C>T Leu286Phe
M0104496 KGOANKCA_00003 2997 3 Skin 0.25 protein_coding missense_variant MODERATE 892G>C Asp298His
M0104497 KGOANKCA_00001 1066 4 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -323C>T None
M0104498 KGOANKCA_00001 928 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -185C>A None
M0104499 KGOANKCA_00003 2174 4 Skin 0.33 protein_coding synonymous_variant LOW 69T>C Thr23Thr
M0104500 KGOANKCA_00003 2183 4 Skin 0.33 protein_coding missense_variant MODERATE 78A>G Ile26Met
M0104501 KGOANKCA_00003 2198 4 Skin 0.33 protein_coding synonymous_variant LOW 93T>C His31His
M0104502 KGOANKCA_00003 2277 3 Skin 0.25 protein_coding missense_variant MODERATE 172C>T Pro58Ser
M0104503 KGOANKCA_00003 2555 3 Skin 0.25 protein_coding synonymous_variant LOW 450A>G Thr150Thr
M0104504 KGOANKCA_00003 3122 3 Skin 0.25 protein_coding synonymous_variant LOW 1017A>G Lys339Lys
M0104505 KGOANKCA_00003 3462 3 Skin 0.25 protein_coding missense_variant MODERATE 1357A>G Lys453Glu
M0104506 KGOANKCA_00003 3476 3 Skin 0.25 protein_coding missense_variant MODERATE 1371C>G Asn457Lys
M0104507 KGOANKCA_00003 3641 3 Skin 0.25 protein_coding synonymous_variant LOW 1536T>C Asp512Asp
M0104508 KGOANKCA_00001 3734 3 Skin 0.25 protein_coding upstream_gene_variant MODIFIER -2991G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term