Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C867
  Reference Plasmid   NZ_CP072217.1
  Reference Plasmid Size   30813
  Reference Plasmid GC Content   0.47
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0185374 JFNGAHIJ_00007 10014 3 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -4984T>C None
M0185375 JFNGAHIJ_00014 10401 3 Gut 0.38 protein_coding synonymous_variant LOW 345A>G Glu115Glu
M0185376 JFNGAHIJ_00014 10584 3 Gut 0.38 protein_coding synonymous_variant LOW 528C>A Ile176Ile
M0185377 JFNGAHIJ_00014 10752 5 Gut 0.63 protein_coding synonymous_variant LOW 696A>C Pro232Pro
M0185378 JFNGAHIJ_00014 10779 5 Gut 0.63 protein_coding synonymous_variant LOW 723G>A Glu241Glu
M0185379 JFNGAHIJ_00016 15982 5 Gut 0.63 protein_coding upstream_gene_variant MODIFIER -3595C>T None
M0185380 JFNGAHIJ_00021 16259 5 Gut 0.63 protein_coding missense_variant MODERATE 266G>C Ser89Thr
M0185381 JFNGAHIJ_00021 16346 4 Gut 0.50 protein_coding missense_variant MODERATE 179A>G Gln60Arg
M0185382 JFNGAHIJ_00023 17626 4 Gut 0.50 protein_coding missense_variant MODERATE 136A>G Ile46Val
M0185383 JFNGAHIJ_00023 17649 4 Gut 0.50 protein_coding missense_variant MODERATE 113A>G Asn38Ser
M0185384 JFNGAHIJ_00023 17650 4 Gut 0.50 protein_coding missense_variant MODERATE 112A>G Asn38Asp
M0185385 JFNGAHIJ_00023 17651 4 Gut 0.50 protein_coding synonymous_variant LOW 111C>G Gly37Gly
M0185386 JFNGAHIJ_00023 17652 4 Gut 0.50 protein_coding missense_variant MODERATE 110G>T Gly37Val
M0185387 JFNGAHIJ_00031 24483 5 Gut 0.63 protein_coding synonymous_variant LOW 450A>G Ala150Ala
M0185388 JFNGAHIJ_00035 27515 6 Gut 0.75 protein_coding missense_variant MODERATE 1970A>G His657Arg
M0185389 JFNGAHIJ_00036 30103 6 Gut 0.75 protein_coding missense_variant MODERATE 7C>A Pro3Thr
M0185390 JFNGAHIJ_00032 30243 5 Gut 0.63 protein_coding upstream_gene_variant MODIFIER -4997T>A None
M0185391 JFNGAHIJ_00002 2310 4 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -253T>C None
M0185392 JFNGAHIJ_00016 16001 3 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -3614G>A None
M0185393 JFNGAHIJ_00016 16008 3 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -3621C>T None
M0185394 JFNGAHIJ_00016 16060 3 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -3673C>T None
M0185395 JFNGAHIJ_00022 16621 3 Gut 0.38 protein_coding synonymous_variant LOW 429A>G Glu143Glu
M0185396 JFNGAHIJ_00022 16735 3 Gut 0.38 protein_coding synonymous_variant LOW 315C>A Ala105Ala
M0185397 JFNGAHIJ_00022 16747 3 Gut 0.38 protein_coding synonymous_variant LOW 303C>A Gly101Gly
M0185398 JFNGAHIJ_00022 16773 3 Gut 0.38 protein_coding synonymous_variant LOW 277C>T Leu93Leu
M0185399 JFNGAHIJ_00022 16774 3 Gut 0.38 protein_coding synonymous_variant LOW 276C>T Leu92Leu
M0185400 JFNGAHIJ_00022 16801 3 Gut 0.38 protein_coding synonymous_variant LOW 249C>T Tyr83Tyr
M0185401 JFNGAHIJ_00022 16825 3 Gut 0.38 protein_coding synonymous_variant LOW 225G>A Thr75Thr
M0185402 JFNGAHIJ_00022 17008 3 Gut 0.38 protein_coding synonymous_variant LOW 42G>A Val14Val
M0185403 JFNGAHIJ_00022 17023 3 Gut 0.38 protein_coding synonymous_variant LOW 27C>T Leu9Leu
M0185404 JFNGAHIJ_00022 17032 3 Gut 0.38 protein_coding synonymous_variant LOW 18A>G Val6Val
M0185405 JFNGAHIJ_00016 17051 3 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -4664T>A None
M0185406 JFNGAHIJ_00016 17053 3 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -4666G>A None
M0185407 JFNGAHIJ_00023 17399 3 Gut 0.38 protein_coding synonymous_variant LOW 363G>T Leu121Leu
M0185408 JFNGAHIJ_00026 19591 3 Gut 0.38 protein_coding synonymous_variant LOW 25C>T Leu9Leu
M0185409 JFNGAHIJ_00034 26565 3 Gut 0.38 protein_coding synonymous_variant LOW 672C>T Ser224Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term