Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C873
  Reference Plasmid   NZ_CP072226.1
  Reference Plasmid Size   8943
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0185668 ACIOLBFJ_00003 1693 4 Gut 0.31 protein_coding synonymous_variant LOW 408A>G Leu136Leu
M0185669 ACIOLBFJ_00007 6394 3 Gut 0.23 protein_coding missense_variant MODERATE 414A>C Glu138Asp
M0185670 ACIOLBFJ_00007 6424 3 Gut 0.23 protein_coding synonymous_variant LOW 384T>C Tyr128Tyr
M0185671 ACIOLBFJ_00007 6446 3 Gut 0.23 protein_coding missense_variant MODERATE 362A>G Lys121Arg
M0185672 ACIOLBFJ_00007 6522 3 Gut 0.23 protein_coding missense_variant MODERATE 286T>C Cys96Arg
M0185673 ACIOLBFJ_00007 6786 4 Gut 0.31 protein_coding missense_variant MODERATE 22A>G Ser8Gly
M0185674 ACIOLBFJ_00008 6833 3 Gut 0.23 protein_coding missense_variant MODERATE 577A>G Asn193Asp
M0185675 ACIOLBFJ_00008 7191 5 Gut 0.38 protein_coding synonymous_variant LOW 219A>G Arg73Arg
M0185676 ACIOLBFJ_00008 7254 3 Gut 0.23 protein_coding synonymous_variant LOW 156G>A Glu52Glu
M0185677 ACIOLBFJ_00008 7314 4 Gut 0.31 protein_coding missense_variant MODERATE 96G>C Glu32Asp
M0185678 ACIOLBFJ_00008 7350 3 Gut 0.23 protein_coding synonymous_variant LOW 60T>C Asp20Asp
M0185679 ACIOLBFJ_00001 837 4 Gut 0.31 protein_coding synonymous_variant LOW 837T>C Asn279Asn






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term