Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C881
  Reference Plasmid   NZ_CP072240.1
  Reference Plasmid Size   8944
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0187196 MPLIJECK_00002 1045 3 Gut 0.27 protein_coding synonymous_variant LOW 54A>G Arg18Arg
M0187197 MPLIJECK_00002 1060 3 Gut 0.27 protein_coding missense_variant MODERATE 69A>G Ile23Met
M0187198 MPLIJECK_00003 1694 4 Gut 0.36 protein_coding synonymous_variant LOW 408A>G Leu136Leu
M0187199 MPLIJECK_00007 6224 3 Gut 0.27 protein_coding synonymous_variant LOW 585C>A Arg195Arg
M0187200 MPLIJECK_00007 6277 3 Gut 0.27 protein_coding missense_variant MODERATE 532G>A Gly178Ser
M0187201 MPLIJECK_00007 6305 4 Gut 0.36 protein_coding synonymous_variant LOW 504G>A Gly168Gly
M0187202 MPLIJECK_00007 6447 3 Gut 0.27 protein_coding missense_variant MODERATE 362A>G Lys121Arg
M0187203 MPLIJECK_00007 6494 3 Gut 0.27 protein_coding synonymous_variant LOW 315G>A Arg105Arg
M0187204 MPLIJECK_00007 6523 4 Gut 0.36 protein_coding missense_variant MODERATE 286T>C Cys96Arg
M0187205 MPLIJECK_00007 6538 3 Gut 0.27 protein_coding missense_variant MODERATE 271A>G Arg91Gly
M0187206 MPLIJECK_00007 6683 3 Gut 0.27 protein_coding synonymous_variant LOW 126G>A Pro42Pro
M0187207 MPLIJECK_00008 7132 3 Gut 0.27 protein_coding synonymous_variant LOW 279A>G Arg93Arg
M0187208 MPLIJECK_00008 7138 3 Gut 0.27 protein_coding synonymous_variant LOW 273C>T Ser91Ser
M0187209 MPLIJECK_00008 7192 5 Gut 0.45 protein_coding synonymous_variant LOW 219A>G Arg73Arg
M0187210 MPLIJECK_00008 7252 5 Gut 0.45 protein_coding synonymous_variant LOW 159T>C Ser53Ser
M0187211 MPLIJECK_00008 7255 5 Gut 0.45 protein_coding synonymous_variant LOW 156G>A Glu52Glu
M0187212 MPLIJECK_00008 7270 3 Gut 0.27 protein_coding synonymous_variant LOW 141C>T Asn47Asn
M0187213 MPLIJECK_00008 7315 5 Gut 0.45 protein_coding missense_variant MODERATE 96G>C Glu32Asp
M0187214 MPLIJECK_00008 7351 3 Gut 0.27 protein_coding synonymous_variant LOW 60T>C Asp20Asp
M0187215 MPLIJECK_00007 7675 3 Gut 0.27 protein_coding upstream_gene_variant MODIFIER -867T>A None
M0187216 MPLIJECK_00007 7711 3 Gut 0.27 protein_coding upstream_gene_variant MODIFIER -903G>T None
M0187217 MPLIJECK_00007 7718 3 Gut 0.27 protein_coding upstream_gene_variant MODIFIER -910C>T None
M0187218 MPLIJECK_00007 7740 3 Gut 0.27 protein_coding upstream_gene_variant MODIFIER -932A>T None
M0187219 MPLIJECK_00007 7741 3 Gut 0.27 protein_coding upstream_gene_variant MODIFIER -933G>T None
M0187220 MPLIJECK_00007 7742 3 Gut 0.27 protein_coding upstream_gene_variant MODIFIER -934T>G None
M0187221 MPLIJECK_00007 7744 3 Gut 0.27 protein_coding upstream_gene_variant MODIFIER -936A>G None
M0187222 MPLIJECK_00007 7746 3 Gut 0.27 protein_coding upstream_gene_variant MODIFIER -938A>T None
M0187223 MPLIJECK_00007 7747 3 Gut 0.27 protein_coding upstream_gene_variant MODIFIER -939A>T None
M0187224 MPLIJECK_00007 6395 3 Gut 0.27 protein_coding missense_variant MODERATE 414A>C Glu138Asp
M0187225 MPLIJECK_00007 6425 3 Gut 0.27 protein_coding synonymous_variant LOW 384T>C Tyr128Tyr
M0187226 MPLIJECK_00007 7457 3 Gut 0.27 protein_coding upstream_gene_variant MODIFIER -649G>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term