Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C882
  Reference Plasmid   NZ_CP072241.1
  Reference Plasmid Size   98234
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0187227 FCNLPPKI_00092 76739 3 Gut 0.02 protein_coding upstream_gene_variant MODIFIER -3793C>A None
M0187228 FCNLPPKI_00104 83684 3 Gut 0.02 protein_coding missense_variant MODERATE 445G>A Val149Ile
M0187229 FCNLPPKI_00109 87921 3 Gut 0.02 protein_coding synonymous_variant LOW 540G>A Val180Val
M0187230 FCNLPPKI_00112 89916 3 Gut 0.02 protein_coding synonymous_variant LOW 1974T>C Ala658Ala
M0187231 FCNLPPKI_00112 89961 3 Gut 0.02 protein_coding synonymous_variant LOW 1929A>G Leu643Leu
M0187232 FCNLPPKI_00112 90147 3 Gut 0.02 protein_coding synonymous_variant LOW 1743A>G Glu581Glu
M0187233 FCNLPPKI_00121 97229 3 Gut 0.02 protein_coding synonymous_variant LOW 651T>G Ala217Ala
M0187234 FCNLPPKI_00092 73513 5 Gut 0.03 protein_coding upstream_gene_variant MODIFIER -567A>G None
M0187235 FCNLPPKI_00092 73540 5 Gut 0.03 protein_coding upstream_gene_variant MODIFIER -594A>G None
M0187236 FCNLPPKI_00092 73542 5 Gut 0.03 protein_coding upstream_gene_variant MODIFIER -596G>A None
M0187237 FCNLPPKI_00059 51289 3 Gut 0.02 protein_coding synonymous_variant LOW 183C>A Ala61Ala
M0187238 FCNLPPKI_00072 60743 4 Gut 0.03 protein_coding synonymous_variant LOW 231G>A Pro77Pro
M0187239 FCNLPPKI_00074 61322 3 Gut 0.02 protein_coding missense_variant MODERATE 244A>G Lys82Glu
M0187240 FCNLPPKI_00065 61957 3 Gut 0.02 protein_coding upstream_gene_variant MODIFIER -4525T>C None
M0187241 FCNLPPKI_00102 82213 3 Gut 0.02 protein_coding missense_variant MODERATE 236A>G Asn79Ser
M0187242 FCNLPPKI_00107 86413 3 Gut 0.02 protein_coding synonymous_variant LOW 303G>A Glu101Glu
M0187243 FCNLPPKI_00111 89254 3 Gut 0.02 protein_coding missense_variant MODERATE 37G>A Gly13Ser
M0187244 FCNLPPKI_00069 59364 5 Gut 0.03 protein_coding missense_variant MODERATE 17G>A Gly6Glu
M0187245 FCNLPPKI_00073 65098 6 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -3874G>A None
M0187246 FCNLPPKI_00073 65113 7 Gut 0.05 protein_coding upstream_gene_variant MODIFIER -3889T>C None
M0187247 FCNLPPKI_00073 65140 6 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -3916A>G None
M0187248 FCNLPPKI_00073 65146 6 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -3922C>T None
M0187249 FCNLPPKI_00073 65577 5 Gut 0.03 protein_coding upstream_gene_variant MODIFIER -4353T>A None
M0187250 FCNLPPKI_00073 65580 5 Gut 0.03 protein_coding upstream_gene_variant MODIFIER -4356G>A None
M0187251 FCNLPPKI_00087 69387 5 Gut 0.03 protein_coding synonymous_variant LOW 234A>G Ala78Ala
M0187252 FCNLPPKI_00024 27802 5 Gut 0.03 protein_coding upstream_gene_variant MODIFIER -4359A>G None
M0187253 FCNLPPKI_00069 59466 3 Gut 0.02 protein_coding missense_variant MODERATE 119T>C Ile40Thr
M0187254 FCNLPPKI_00066 62658 4 Gut 0.03 protein_coding upstream_gene_variant MODIFIER -4855G>T None
M0187255 FCNLPPKI_00067 63189 3 Gut 0.02 protein_coding upstream_gene_variant MODIFIER -4517T>C None
M0187256 FCNLPPKI_00078 63608 3 Gut 0.02 protein_coding synonymous_variant LOW 120G>A Ala40Ala
M0187257 FCNLPPKI_00078 63617 3 Gut 0.02 protein_coding synonymous_variant LOW 129T>C Tyr43Tyr
M0187258 FCNLPPKI_00065 62028 3 Gut 0.02 protein_coding upstream_gene_variant MODIFIER -4596A>G None
M0187259 FCNLPPKI_00065 62169 6 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -4737G>A None
M0187260 FCNLPPKI_00065 62173 5 Gut 0.03 protein_coding upstream_gene_variant MODIFIER -4741C>A None
M0187261 FCNLPPKI_00065 62223 3 Gut 0.02 protein_coding upstream_gene_variant MODIFIER -4791G>A None
M0187262 FCNLPPKI_00065 62259 4 Gut 0.03 protein_coding upstream_gene_variant MODIFIER -4827C>A None
M0187263 FCNLPPKI_00065 62305 5 Gut 0.03 protein_coding upstream_gene_variant MODIFIER -4873T>A None
M0187264 FCNLPPKI_00065 62320 5 Gut 0.03 protein_coding upstream_gene_variant MODIFIER -4888A>G None
M0187265 FCNLPPKI_00065 62329 4 Gut 0.03 protein_coding upstream_gene_variant MODIFIER -4897C>A None
M0187266 FCNLPPKI_00065 62341 4 Gut 0.03 protein_coding upstream_gene_variant MODIFIER -4909G>A None
M0187267 FCNLPPKI_00065 62352 3 Gut 0.02 protein_coding upstream_gene_variant MODIFIER -4920G>A None
M0187268 FCNLPPKI_00027 25330 4 Gut 0.03 protein_coding synonymous_variant LOW 18A>C Ala6Ala
M0187269 FCNLPPKI_00024 27639 3 Gut 0.02 protein_coding upstream_gene_variant MODIFIER -4196T>G None
M0187270 FCNLPPKI_00024 27704 3 Gut 0.02 protein_coding upstream_gene_variant MODIFIER -4261G>A None
M0187271 FCNLPPKI_00024 27720 3 Gut 0.02 protein_coding upstream_gene_variant MODIFIER -4277G>T None
M0187272 FCNLPPKI_00024 27747 3 Gut 0.02 protein_coding upstream_gene_variant MODIFIER -4304A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
FCNLPPKI_00021 PHI:3281 AS87_04050 71.4 3e-136 1 325 1.0000 1.0000 birds fibrinous serositis; caseous salpingitis; vegetative disorder lipopolysaccharide biosynthesis and pathogenicity reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
FCNLPPKI_00009 QUT64421.1|GT4 100 1.11e-279 1 378 1 1
FCNLPPKI_00011 QUT55894.1|GT2 100 1.57e-228 1 304 1 1
FCNLPPKI_00013 QRP91616.1|GT4 100 5.41e-274 1 366 1 1
FCNLPPKI_00014 BBK89584.1|GT2 100 6.37e-226 1 300 1 1
FCNLPPKI_00015 QRP91614.1|GT4 100 4.79e-292 1 391 1 1
FCNLPPKI_00016 QUT83193.1|GT4 100 0 1 444 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term