Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C909
  Reference Plasmid   NZ_CP076524.1
  Reference Plasmid Size   41535
  Reference Plasmid GC Content   0.40
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0104522 LBGMPFHD_00025 14402 5 Skin 0.63 protein_coding missense_variant MODERATE 875A>G Asp292Gly
M0104523 LBGMPFHD_00025 15131 5 Skin 0.63 protein_coding missense_variant MODERATE 146C>T Ala49Val
M0104524 LBGMPFHD_00041 21482 6 Skin 0.75 protein_coding synonymous_variant LOW 267T>A Pro89Pro
M0104525 LBGMPFHD_00042 22141 6 Skin 0.75 protein_coding synonymous_variant LOW 498C>T Asp166Asp
M0104526 LBGMPFHD_00034 22869 5 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -4990C>T None
M0104527 LBGMPFHD_00023 13334 5 Skin 0.63 protein_coding missense_variant MODERATE 275A>C Tyr92Ser
M0104528 LBGMPFHD_00024 14260 4 Skin 0.50 protein_coding missense_variant MODERATE 136C>A Gln46Lys
M0104529 LBGMPFHD_00029 16235 5 Skin 0.63 protein_coding synonymous_variant LOW 207G>A Lys69Lys
M0104530 LBGMPFHD_00034 17683 5 Skin 0.63 protein_coding missense_variant MODERATE 197A>G Tyr66Cys
M0104531 LBGMPFHD_00041 21392 5 Skin 0.63 protein_coding synonymous_variant LOW 177T>A Gly59Gly
M0104532 LBGMPFHD_00041 21395 5 Skin 0.63 protein_coding synonymous_variant LOW 180C>T Arg60Arg
M0104533 LBGMPFHD_00041 21398 5 Skin 0.63 protein_coding synonymous_variant LOW 183C>T Tyr61Tyr
M0104534 LBGMPFHD_00041 21410 5 Skin 0.63 protein_coding synonymous_variant LOW 195C>T Ser65Ser
M0104535 LBGMPFHD_00041 21414 5 Skin 0.63 protein_coding missense_variant MODERATE 199C>T Leu67Phe
M0104536 LBGMPFHD_00041 21416 5 Skin 0.63 protein_coding synonymous_variant LOW 201C>A Leu67Leu
M0104537 LBGMPFHD_00041 21419 5 Skin 0.63 protein_coding synonymous_variant LOW 204A>T Thr68Thr
M0104538 LBGMPFHD_00041 21422 5 Skin 0.63 protein_coding synonymous_variant LOW 207C>T His69His
M0104539 LBGMPFHD_00042 22652 4 Skin 0.50 protein_coding missense_variant MODERATE 1009A>G Arg337Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
LBGMPFHD_00046 QWS36907.1|GH25 100 2.57e-271 1 373 1 1
LBGMPFHD_00062 QGS06751.1|CBM50 99.6 1.32e-177 1 250 1 0.7886
PIMMABOD_00046 QWS36907.1|GH25 100 2.57e-271 1 373 1 1
PIMMABOD_00062 QGS06751.1|CBM50 99.6 1.32e-177 1 250 1 0.7886
NDLFFLEA_00046 QWS36907.1|GH25 100 2.57e-271 1 373 1 1
NDLFFLEA_00062 QGS06751.1|CBM50 99.6 1.32e-177 1 250 1 0.7886





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term