Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C912
  Reference Plasmid   NZ_CP076694.1
  Reference Plasmid Size   146805
  Reference Plasmid GC Content   0.51
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0188479 GFCJGOKJ_00060 54100 3 Gut 0.50 protein_coding synonymous_variant LOW 195T>C Arg65Arg
M0188480 GFCJGOKJ_00061 54542 3 Gut 0.50 protein_coding missense_variant MODERATE 136G>A Val46Met
M0188481 GFCJGOKJ_00062 54927 3 Gut 0.50 protein_coding missense_variant MODERATE 2375G>A Arg792Lys
M0188482 GFCJGOKJ_00062 55394 3 Gut 0.50 protein_coding synonymous_variant LOW 1908T>C Gly636Gly
M0188483 GFCJGOKJ_00069 61825 3 Gut 0.50 protein_coding missense_variant MODERATE 94G>C Val32Leu
M0188484 GFCJGOKJ_00070 62030 3 Gut 0.50 protein_coding synonymous_variant LOW 222A>T Arg74Arg
M0188485 GFCJGOKJ_00070 62117 3 Gut 0.50 protein_coding synonymous_variant LOW 135A>G Ser45Ser
M0188486 GFCJGOKJ_00070 62140 3 Gut 0.50 protein_coding missense_variant MODERATE 112A>G Ile38Val
M0188487 GFCJGOKJ_00070 62150 3 Gut 0.50 protein_coding synonymous_variant LOW 102C>A Ala34Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
GFCJGOKJ_00073 VFG001445 TraJ 73.7 1.6e-76 2 191 0.8444 0.9453 Invasion unknown protein experiment
GFCJGOKJ_00073 VFG001445 TraJ 73.7 1.2e-75 2 191 0.8444 0.9453 Invasion unknown protein prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
GFCJGOKJ_00115 PHI:3317 hsdR 73.2 0 1 1038 1.0000 1.0000 rodents Glasser's disease involved in pathogenicity reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
GFCJGOKJ_00075 QAZ75040.1|GH23 100 4.96e-124 1 169 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
GFCJGOKJ_00125 2.A.3.1.10 99.8 4.6e-266 9 475 0.9832 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.3 The Amino Acid-Polyamine-Organocation (APC) Family
GFCJGOKJ_00156 2.A.10.1.2 71 7.9e-121 1 317 0.9875 0.9664 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.10 The 2-Keto-3-Deoxygluconate Transporter (KdgT) Family
GFCJGOKJ_00171 2.A.108.2.10 100 0 1 628 1.0000 3.6301 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.108 The Iron/Lead Transporter (ILT) Family
GFCJGOKJ_00172 2.A.108.2.10 100 5e-101 3 175 0.9886 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.108 The Iron/Lead Transporter (ILT) Family