Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C918
  Reference Plasmid   NZ_CP077892.1
  Reference Plasmid Size   24233
  Reference Plasmid GC Content   0.33
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0104780 LDLBGOAH_00014 10567 3 Skin 1.00 protein_coding synonymous_variant LOW 270A>G Leu90Leu
M0104781 LDLBGOAH_00014 10637 3 Skin 1.00 protein_coding missense_variant MODERATE 200C>T Ser67Leu
M0104782 LDLBGOAH_00011 12162 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -4220C>T None
M0104783 LDLBGOAH_00011 12232 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -4290G>T None
M0104784 LDLBGOAH_00011 12241 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -4299A>T None
M0104785 LDLBGOAH_00016 12467 3 Skin 1.00 protein_coding synonymous_variant LOW 162A>G Ser54Ser
M0104786 LDLBGOAH_00016 12581 3 Skin 1.00 protein_coding synonymous_variant LOW 276A>T Val92Val
M0104787 LDLBGOAH_00016 12608 3 Skin 1.00 protein_coding synonymous_variant LOW 303A>G Ala101Ala
M0104788 LDLBGOAH_00016 12617 3 Skin 1.00 protein_coding synonymous_variant LOW 312A>G Ala104Ala
M0104789 LDLBGOAH_00016 12626 3 Skin 1.00 protein_coding synonymous_variant LOW 321T>A Ala107Ala
M0104790 LDLBGOAH_00016 12633 3 Skin 1.00 protein_coding missense_variant MODERATE 328A>G Ile110Val
M0104791 LDLBGOAH_00016 12635 3 Skin 1.00 protein_coding missense_variant MODERATE 330T>G Ile110Met
M0104792 LDLBGOAH_00016 12657 3 Skin 1.00 protein_coding missense_variant MODERATE 352A>G Ile118Val
M0104793 LDLBGOAH_00016 12686 3 Skin 1.00 protein_coding synonymous_variant LOW 381C>T Ser127Ser
M0104794 LDLBGOAH_00011 12715 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -4773T>G None
M0104795 LDLBGOAH_00011 12716 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -4774T>C None
M0104796 LDLBGOAH_00011 12724 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -4782A>G None
M0104797 LDLBGOAH_00011 12727 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -4785C>T None
M0104798 LDLBGOAH_00011 12729 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -4787G>A None
M0104799 LDLBGOAH_00011 12770 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -4828C>T None
M0104800 LDLBGOAH_00011 12844 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -4902T>C None
M0104801 LDLBGOAH_00011 12862 3 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -4920T>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
LDLBGOAH_00001 PHI:123153 NWMN2330 98.1 2.6e-21 1 52 1.0000 1.0000 rodents skin infection; food poisoning; respiratory disease virulence factor reduced virulence
LDLBGOAH_00016 PHI:123153 NWMN2330 100 4.9e-66 1 128 1.0000 1.0000 rodents skin infection; food poisoning; respiratory disease virulence factor reduced virulence
CMCLKGNM_00001 PHI:123153 NWMN2330 98.1 2.6e-21 1 52 1.0000 1.0000 rodents skin infection; food poisoning; respiratory disease virulence factor reduced virulence
CMCLKGNM_00016 PHI:123153 NWMN2330 100 4.9e-66 1 128 1.0000 1.0000 rodents skin infection; food poisoning; respiratory disease virulence factor reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
LDLBGOAH_00016 2.A.129.1.7 100 1.1e-65 1 128 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.129 The Lipid-linked Sugar Translocase (LST) Family
CMCLKGNM_00016 2.A.129.1.7 100 1.1e-65 1 128 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.129 The Lipid-linked Sugar Translocase (LST) Family