Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C924
  Reference Plasmid   NZ_CP079635.1
  Reference Plasmid Size   1039047
  Reference Plasmid GC Content   0.57
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0188547 HKGNBBPO_00009 13610 3 Gut 0.15 protein_coding upstream_gene_variant MODIFIER -4197C>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
NGINNMPJ_00047 VFG044333 Ybt 99.9 0 1 673 1.0 1 Nutritional/Metabolic factor yersiniabactin receptor FyuA experiment
NGINNMPJ_00048 VFG000359 Yersiniabactin 99.8 2.3e-304 1 525 1.0 1 Nutritional/Metabolic factor yersiniabactin siderophore biosynthetic protein experiment
NGINNMPJ_00049 VFG000360 Yersiniabactin 99.6 9.4e-161 1 267 1.0 1 Nutritional/Metabolic factor type II thioesterase YbtT experiment
NGINNMPJ_00050 VFG000361 Yersiniabactin 100 1.4e-223 1 366 1.0 1 Nutritional/Metabolic factor yersiniabactin biosynthetic protein YbtU experiment
NGINNMPJ_00051 VFG000362 Yersiniabactin 99.9 0 1 3163 1.0 1 Nutritional/Metabolic factor yersiniabactin biosynthetic protein Irp1 experiment
NGINNMPJ_00052 VFG000363 Yersiniabactin 99.9 0 1 2035 1.0 1 Nutritional/Metabolic factor yersiniabactin biosynthetic protein Irp2 experiment
NGINNMPJ_00053 VFG044327 Ybt 100 1.3e-188 1 319 1.0 1 Nutritional/Metabolic factor yersiniabactin transcriptional regulator YbtA experiment
NGINNMPJ_00054 VFG044326 Ybt 100 0 31 600 0.95 1 Nutritional/Metabolic factor yersiniabactin ABC transporter ATP-binding/permease protein YbtP experiment
NGINNMPJ_00055 VFG044325 Ybt 99.7 0 1 600 1.0 1 Nutritional/Metabolic factor yersiniabactin ABC transporter ATP-binding/permease protein YbtQ experiment
NGINNMPJ_00056 VFG000367 Yersiniabactin 98.1 3e-225 1 426 1.0 1 Nutritional/Metabolic factor putative signal transducer experiment
NGINNMPJ_00057 VFG000368 Yersiniabactin 98 2.4e-176 1 307 0.9777 0.7074 Nutritional/Metabolic factor salicylate synthase Irp9 experiment
NGINNMPJ_00112 VFG049007 RcsAB 100 3e-114 1 207 1.0 1 Regulation transcriptional activator for ctr capsule biosynthesis experiment
NGINNMPJ_00364 VFG013465 LOS 83 3.4e-137 1 283 0.9965 0.9965 Immune modulation 2-dehydro-3-deoxyphosphooctonate aldolase experiment
NGINNMPJ_00392 VFG013346 LOS 74.7 2.6e-119 10 295 0.9533 0.9695 Immune modulation glucosephosphate uridylyltransferase experiment
NGINNMPJ_00798 VFG000575 MgtC 70.9 1.3e-83 1 223 0.9867 0.9654 Nutritional/Metabolic factor Salmonella virulence protein MgtC experiment
NGINNMPJ_00929 VFG044322 Sal 99.3 7e-173 2 299 0.9967 0.9582 Nutritional/Metabolic factor siderophore esterase IroE experiment
HKGNBBPO_00047 VFG044333 Ybt 99.9 0 1 673 1.0 1 Nutritional/Metabolic factor yersiniabactin receptor FyuA experiment
HKGNBBPO_00048 VFG000359 Yersiniabactin 99.8 2.3e-304 1 525 1.0 1 Nutritional/Metabolic factor yersiniabactin siderophore biosynthetic protein experiment
HKGNBBPO_00049 VFG000360 Yersiniabactin 99.6 9.4e-161 1 267 1.0 1 Nutritional/Metabolic factor type II thioesterase YbtT experiment
HKGNBBPO_00050 VFG000361 Yersiniabactin 100 1.4e-223 1 366 1.0 1 Nutritional/Metabolic factor yersiniabactin biosynthetic protein YbtU experiment
HKGNBBPO_00051 VFG000362 Yersiniabactin 99.9 0 1 3163 1.0 1 Nutritional/Metabolic factor yersiniabactin biosynthetic protein Irp1 experiment
HKGNBBPO_00052 VFG000363 Yersiniabactin 99.9 0 1 2035 1.0 1 Nutritional/Metabolic factor yersiniabactin biosynthetic protein Irp2 experiment
HKGNBBPO_00053 VFG044327 Ybt 100 1.3e-188 1 319 1.0 1 Nutritional/Metabolic factor yersiniabactin transcriptional regulator YbtA experiment
HKGNBBPO_00054 VFG044326 Ybt 100 0 31 600 0.95 1 Nutritional/Metabolic factor yersiniabactin ABC transporter ATP-binding/permease protein YbtP experiment
HKGNBBPO_00055 VFG044325 Ybt 99.7 0 1 600 1.0 1 Nutritional/Metabolic factor yersiniabactin ABC transporter ATP-binding/permease protein YbtQ experiment
HKGNBBPO_00056 VFG000367 Yersiniabactin 98.1 3e-225 1 426 1.0 1 Nutritional/Metabolic factor putative signal transducer experiment
HKGNBBPO_00057 VFG000368 Yersiniabactin 98 2.4e-176 1 307 0.9777 0.7074 Nutritional/Metabolic factor salicylate synthase Irp9 experiment
HKGNBBPO_00112 VFG049007 RcsAB 100 3e-114 1 207 1.0 1 Regulation transcriptional activator for ctr capsule biosynthesis experiment
HKGNBBPO_00364 VFG013465 LOS 83 3.4e-137 1 283 0.9965 0.9965 Immune modulation 2-dehydro-3-deoxyphosphooctonate aldolase experiment
HKGNBBPO_00392 VFG013346 LOS 74.7 2.6e-119 10 295 0.9533 0.9695 Immune modulation glucosephosphate uridylyltransferase experiment
HKGNBBPO_00798 VFG000575 MgtC 70.9 1.3e-83 1 223 0.9867 0.9654 Nutritional/Metabolic factor Salmonella virulence protein MgtC experiment
HKGNBBPO_00929 VFG044322 Sal 99.3 7e-173 2 299 0.9967 0.9582 Nutritional/Metabolic factor siderophore esterase IroE experiment
NGINNMPJ_00047 VFG048597 Ybt 100 0 1 673 1.0 1 Nutritional/Metabolic factor yersiniabactin receptor FyuA prediction
NGINNMPJ_00048 VFG000359 Yersiniabactin 99.8 1.7e-303 1 525 1.0 1 Nutritional/Metabolic factor yersiniabactin siderophore biosynthetic protein prediction
NGINNMPJ_00049 VFG034147 Yersiniabactin siderophore 100 2.4e-160 1 267 1.0 1 Nutritional/Metabolic factor yersiniabactin biosynthesis thioesterase YbtT prediction
NGINNMPJ_00050 VFG034135 Yersiniabactin siderophore 100 1e-222 1 366 1.0 1 Nutritional/Metabolic factor yersiniabactin biosynthesis oxidoreductase YbtU prediction
NGINNMPJ_00051 VFG000362 Yersiniabactin 99.9 0 1 3163 1.0 1 Nutritional/Metabolic factor yersiniabactin biosynthetic protein Irp1 prediction
NGINNMPJ_00052 VFG012549 Yersiniabactin siderophore 99.9 0 1 2035 1.0 1 Nutritional/Metabolic factor yersiniabactin non-ribosomal peptide synthetase HMWP2 prediction
NGINNMPJ_00053 VFG034084 Yersiniabactin siderophore 100 9.5e-188 1 319 1.0 1 Nutritional/Metabolic factor yersiniabactin transcriptional regulator YbtA prediction
NGINNMPJ_00054 VFG012539 Yersiniabactin siderophore 100 0 31 600 0.95 1 Nutritional/Metabolic factor yersiniabactin ABC transporter ATP-binding/permease protein YbtP prediction
NGINNMPJ_00055 VFG000366 Yersiniabactin 99.7 0 1 600 1.0 1 Nutritional/Metabolic factor yersiniabactin ABC transporter ATP-binding/permease protein YbtQ prediction
NGINNMPJ_00056 VFG048562 Ybt 98.8 3.1e-226 1 426 1.0 1 Nutritional/Metabolic factor yersiniabactin-associated zinc MFS transporter YbtX prediction
NGINNMPJ_00057 VFG003509 Yersiniabactin 98 1.8e-175 1 307 0.9777 0.7074 Nutritional/Metabolic factor salicylate synthase Irp9 prediction
NGINNMPJ_00077 VFG013051 Ferrous iron transport 83.3 7.6e-128 1 275 0.9615 0.9649 Nutritional/Metabolic factor iron/manganese ABC transporter permease subunit SitC prediction
NGINNMPJ_00078 VFG013050 Ferrous iron transport 73.6 1.9e-96 1 239 0.8755 0.8691 Nutritional/Metabolic factor iron/manganese ABC transporter ATP-binding protein SitB prediction
NGINNMPJ_00079 VFG012575 Iron/manganese transport 76.3 7.5e-134 1 304 1.0 1 Nutritional/Metabolic factor iron/manganese ABC transporter substrate-binding protein SitA prediction
NGINNMPJ_00112 VFG049007 RcsAB 100 2.2e-113 1 207 1.0 1 Regulation transcriptional activator for ctr capsule biosynthesis prediction
NGINNMPJ_00115 VFG043099 Peritrichous flagella 89.8 4.7e-129 1 255 1.0 0.9586 Motility cystine ABC transporter substrate-binding protein prediction
NGINNMPJ_00325 VFG049213 T6SS-III 99.8 1.5e-252 1 446 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssK prediction
NGINNMPJ_00326 VFG049220 T6SS-III 100 1.5e-123 1 217 1.0 1 Effector delivery system type VI secretion system protein TssL, short form prediction
NGINNMPJ_00327 VFG049231 T6SS-III 98.9 0 1 565 1.0 1 Effector delivery system OmpA family protein prediction
NGINNMPJ_00329 VFG049245 T6SS-III 98.4 0 1 828 1.0 1 Effector delivery system type VI secretion system tip protein VgrG prediction
NGINNMPJ_00341 VFG035228 SCI-I T6SS 79.5 5e-38 1 88 1.0 1 Effector delivery system PAAR domain-containing protein prediction
NGINNMPJ_00343 VFG049259 T6SS-III 97.2 0 1 1136 1.0 1 Effector delivery system type VI secretion protein VasK prediction
NGINNMPJ_00344 VFG049266 T6SS-III 99.7 0 1 587 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssF prediction
NGINNMPJ_00345 VFG049276 T6SS-III 99.7 4.8e-201 11 348 0.9713 1 Effector delivery system type VI secretion system baseplate subunit TssG prediction
NGINNMPJ_00346 VFG049284 T6SS-III 100 8.1e-96 1 178 1.0 1 Effector delivery system type VI secretion system lipoprotein TssJ prediction
NGINNMPJ_00347 VFG049294 T6SS-III 100 5.1e-80 1 147 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssE prediction
NGINNMPJ_00348 VFG049308 T6SS-III 99.4 4.9e-265 1 471 1.0 1 Effector delivery system type VI secretion system ImpA family N-terminal domain-containing protein prediction
NGINNMPJ_00349 VFG049313 T6SS-III 100 7.4e-166 1 304 1.0 1 Effector delivery system sugar ABC transporter substrate-binding protein prediction
NGINNMPJ_00350 VFG049322 T6SS-III 98.2 2.3e-53 1 109 1.0 1 Effector delivery system DUF1869 domain-containing protein prediction
NGINNMPJ_00364 VFG013466 LOS 83.4 5.2e-137 1 283 0.9965 0.9965 Immune modulation 2-dehydro-3-deoxyphosphooctonate aldolase prediction
NGINNMPJ_00392 VFG013348 LOS 74.3 5.2e-119 10 295 0.9533 0.9695 Immune modulation glucosephosphate uridylyltransferase prediction
NGINNMPJ_00798 VFG004044 MgtC 70.9 5.9e-83 1 223 0.9867 0.9654 Nutritional/Metabolic factor Salmonella virulence protein MgtC prediction
NGINNMPJ_00929 VFG048536 Sal 100 9.5e-174 2 299 0.9967 0.9582 Nutritional/Metabolic factor siderophore esterase IroE prediction
HKGNBBPO_00047 VFG048597 Ybt 100 0 1 673 1.0 1 Nutritional/Metabolic factor yersiniabactin receptor FyuA prediction
HKGNBBPO_00048 VFG000359 Yersiniabactin 99.8 1.7e-303 1 525 1.0 1 Nutritional/Metabolic factor yersiniabactin siderophore biosynthetic protein prediction
HKGNBBPO_00049 VFG034147 Yersiniabactin siderophore 100 2.4e-160 1 267 1.0 1 Nutritional/Metabolic factor yersiniabactin biosynthesis thioesterase YbtT prediction
HKGNBBPO_00050 VFG034135 Yersiniabactin siderophore 100 1e-222 1 366 1.0 1 Nutritional/Metabolic factor yersiniabactin biosynthesis oxidoreductase YbtU prediction
HKGNBBPO_00051 VFG000362 Yersiniabactin 99.9 0 1 3163 1.0 1 Nutritional/Metabolic factor yersiniabactin biosynthetic protein Irp1 prediction
HKGNBBPO_00052 VFG012549 Yersiniabactin siderophore 99.9 0 1 2035 1.0 1 Nutritional/Metabolic factor yersiniabactin non-ribosomal peptide synthetase HMWP2 prediction
HKGNBBPO_00053 VFG034084 Yersiniabactin siderophore 100 9.5e-188 1 319 1.0 1 Nutritional/Metabolic factor yersiniabactin transcriptional regulator YbtA prediction
HKGNBBPO_00054 VFG012539 Yersiniabactin siderophore 100 0 31 600 0.95 1 Nutritional/Metabolic factor yersiniabactin ABC transporter ATP-binding/permease protein YbtP prediction
HKGNBBPO_00055 VFG000366 Yersiniabactin 99.7 0 1 600 1.0 1 Nutritional/Metabolic factor yersiniabactin ABC transporter ATP-binding/permease protein YbtQ prediction
HKGNBBPO_00056 VFG048562 Ybt 98.8 3.1e-226 1 426 1.0 1 Nutritional/Metabolic factor yersiniabactin-associated zinc MFS transporter YbtX prediction
HKGNBBPO_00057 VFG003509 Yersiniabactin 98 1.8e-175 1 307 0.9777 0.7074 Nutritional/Metabolic factor salicylate synthase Irp9 prediction
HKGNBBPO_00077 VFG013051 Ferrous iron transport 83.3 7.6e-128 1 275 0.9615 0.9649 Nutritional/Metabolic factor iron/manganese ABC transporter permease subunit SitC prediction
HKGNBBPO_00078 VFG013050 Ferrous iron transport 73.6 1.9e-96 1 239 0.8755 0.8691 Nutritional/Metabolic factor iron/manganese ABC transporter ATP-binding protein SitB prediction
HKGNBBPO_00079 VFG012575 Iron/manganese transport 76.3 7.5e-134 1 304 1.0 1 Nutritional/Metabolic factor iron/manganese ABC transporter substrate-binding protein SitA prediction
HKGNBBPO_00112 VFG049007 RcsAB 100 2.2e-113 1 207 1.0 1 Regulation transcriptional activator for ctr capsule biosynthesis prediction
HKGNBBPO_00115 VFG043099 Peritrichous flagella 89.8 4.7e-129 1 255 1.0 0.9586 Motility cystine ABC transporter substrate-binding protein prediction
HKGNBBPO_00325 VFG049213 T6SS-III 99.8 1.5e-252 1 446 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssK prediction
HKGNBBPO_00326 VFG049220 T6SS-III 100 1.5e-123 1 217 1.0 1 Effector delivery system type VI secretion system protein TssL, short form prediction
HKGNBBPO_00327 VFG049231 T6SS-III 98.9 0 1 565 1.0 1 Effector delivery system OmpA family protein prediction
HKGNBBPO_00329 VFG049245 T6SS-III 98.4 0 1 828 1.0 1 Effector delivery system type VI secretion system tip protein VgrG prediction
HKGNBBPO_00341 VFG035228 SCI-I T6SS 79.5 5e-38 1 88 1.0 1 Effector delivery system PAAR domain-containing protein prediction
HKGNBBPO_00343 VFG049259 T6SS-III 97.2 0 1 1136 1.0 1 Effector delivery system type VI secretion protein VasK prediction
HKGNBBPO_00344 VFG049266 T6SS-III 99.7 0 1 587 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssF prediction
HKGNBBPO_00345 VFG049276 T6SS-III 99.7 4.8e-201 11 348 0.9713 1 Effector delivery system type VI secretion system baseplate subunit TssG prediction
HKGNBBPO_00346 VFG049284 T6SS-III 100 8.1e-96 1 178 1.0 1 Effector delivery system type VI secretion system lipoprotein TssJ prediction
HKGNBBPO_00347 VFG049294 T6SS-III 100 5.1e-80 1 147 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssE prediction
HKGNBBPO_00348 VFG049308 T6SS-III 99.4 4.9e-265 1 471 1.0 1 Effector delivery system type VI secretion system ImpA family N-terminal domain-containing protein prediction
HKGNBBPO_00349 VFG049313 T6SS-III 100 7.4e-166 1 304 1.0 1 Effector delivery system sugar ABC transporter substrate-binding protein prediction
HKGNBBPO_00350 VFG049322 T6SS-III 98.2 2.3e-53 1 109 1.0 1 Effector delivery system DUF1869 domain-containing protein prediction
HKGNBBPO_00364 VFG013466 LOS 83.4 5.2e-137 1 283 0.9965 0.9965 Immune modulation 2-dehydro-3-deoxyphosphooctonate aldolase prediction
HKGNBBPO_00392 VFG013348 LOS 74.3 5.2e-119 10 295 0.9533 0.9695 Immune modulation glucosephosphate uridylyltransferase prediction
HKGNBBPO_00798 VFG004044 MgtC 70.9 5.9e-83 1 223 0.9867 0.9654 Nutritional/Metabolic factor Salmonella virulence protein MgtC prediction
HKGNBBPO_00929 VFG048536 Sal 100 9.5e-174 2 299 0.9967 0.9582 Nutritional/Metabolic factor siderophore esterase IroE prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
NGINNMPJ_00039 Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Rhodamine 6G [class: Xanthene] 81.8 2.2e-216 14 470 0.9442 0.9892 experiment
NGINNMPJ_00054 Iron (Fe) 99.8 0 1 600 1.0000 1.0000 experiment
NGINNMPJ_00055 Iron (Fe) 99.7 0 1 600 1.0000 1.0000 experiment
NGINNMPJ_00077 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 77.7 5.3e-125 1 283 0.9895 0.9895 experiment
NGINNMPJ_00079 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 73.3 3.4e-130 1 303 0.9967 0.9934 experiment
NGINNMPJ_00110 Cadmium (Cd), Hydrogen Peroxide (H2O2) [class: Peroxides], Hydrochloric acid (HCl) [class: Acid] 72.6 6.3e-22 13 74 0.8378 0.8267 experiment
NGINNMPJ_00223 Chromium (Cr), Tellurium (Te), Selenium (Se) 72.2 6.4e-138 1 334 0.9970 0.9517 experiment
NGINNMPJ_00224 Zinc (Zn) 92.7 1.5e-126 1 261 1.0000 1.0000 experiment
NGINNMPJ_00225 Zinc (Zn) 90.4 1.4e-129 1 250 1.0000 0.9960 experiment
NGINNMPJ_00226 Zinc (Zn) 76.4 2.8e-135 6 319 0.9843 1.0129 experiment
NGINNMPJ_00262 Manganese (Mn), Magnesium (Mg), Methyl Viologen [class: Paraquat], Hydrogen Peroxide (H2O2) [class: Peroxides] 82.4 1.5e-88 1 188 1.0000 1.0000 experiment
NGINNMPJ_00286 Cadmium (Cd), Mercury (Hg) 79.5 2.3e-86 1 176 1.0000 1.0000 experiment
NGINNMPJ_00353 Cadmium (Cd), Hydrogen Peroxide (H2O2) [class: Peroxides] 88.8 4.2e-44 1 89 0.9780 0.9674 experiment
NGINNMPJ_00607 Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Sodium Deoxycholate (SDC) [class: Acid], Ethidium Bromide [class: Phenanthridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Acriflavine [class: Acridine] 87.3 2.1e-224 1 457 1.0000 1.0000 experiment
NGINNMPJ_00615 Chlorhexidine [class: Biguanides] 89.6 3.5e-104 1 193 1.0000 0.8616 experiment
NGINNMPJ_00615 Selenium (Se), Hydrogen Peroxide (H2O2) [class: Peroxides] 89.6 3.5e-104 1 193 1.0000 0.8616 experiment
NGINNMPJ_00669 Tellurium (Te), Proflavin [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Crystal Violet [class: Triarylmethane], Dequalinium [class: Quaternary Ammonium Compounds (QACs)], Methyl Viologen [class: Paraquat] 77.5 4.5e-144 9 332 0.9701 0.9818 experiment
NGINNMPJ_00670 Tellurium (Te), Proflavin [class: Acridine] 75.5 4.4e-86 1 196 0.9899 0.9949 experiment
NGINNMPJ_00737 Acriflavine [class: Acridine], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamindine], Hoechst 33342 [class: Bisbenzimide], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Methyl Viologen [class: Paraquat], Ethidium Bromide [class: Phenanthridine], Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)] 99.8 1.6e-254 1 499 1.0000 1.0000 experiment
NGINNMPJ_00746 Methyl Viologen [class: Paraquat] 76 4.9e-126 1 292 1.0000 0.9966 experiment
NGINNMPJ_00993 Cyclohexane [class: Cycloalkane], Diphenyl Ether [class: Phenyl], n-hexane [class: Alkane] 84 6.7e-68 1 144 1.0000 1.0000 experiment
NGINNMPJ_00994 Cyclohexane [class: Cycloalkane], Diphenyl Ether [class: Phenyl], n-hexane [class: Alkane] 92.7 2.7e-65 1 124 1.0000 0.9764 experiment
HKGNBBPO_00039 Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Rhodamine 6G [class: Xanthene] 81.8 2.2e-216 14 470 0.9442 0.9892 experiment
HKGNBBPO_00054 Iron (Fe) 99.8 0 1 600 1.0000 1.0000 experiment
HKGNBBPO_00055 Iron (Fe) 99.7 0 1 600 1.0000 1.0000 experiment
HKGNBBPO_00077 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 77.7 5.3e-125 1 283 0.9895 0.9895 experiment
HKGNBBPO_00079 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 73.3 3.4e-130 1 303 0.9967 0.9934 experiment
HKGNBBPO_00110 Cadmium (Cd), Hydrogen Peroxide (H2O2) [class: Peroxides], Hydrochloric acid (HCl) [class: Acid] 72.6 6.3e-22 13 74 0.8378 0.8267 experiment
HKGNBBPO_00223 Chromium (Cr), Tellurium (Te), Selenium (Se) 72.2 6.4e-138 1 334 0.9970 0.9517 experiment
HKGNBBPO_00224 Zinc (Zn) 92.7 1.5e-126 1 261 1.0000 1.0000 experiment
HKGNBBPO_00225 Zinc (Zn) 90.4 1.4e-129 1 250 1.0000 0.9960 experiment
HKGNBBPO_00226 Zinc (Zn) 76.4 2.8e-135 6 319 0.9843 1.0129 experiment
HKGNBBPO_00262 Manganese (Mn), Magnesium (Mg), Methyl Viologen [class: Paraquat], Hydrogen Peroxide (H2O2) [class: Peroxides] 82.4 1.5e-88 1 188 1.0000 1.0000 experiment
HKGNBBPO_00286 Cadmium (Cd), Mercury (Hg) 79.5 2.3e-86 1 176 1.0000 1.0000 experiment
HKGNBBPO_00353 Cadmium (Cd), Hydrogen Peroxide (H2O2) [class: Peroxides] 88.8 4.2e-44 1 89 0.9780 0.9674 experiment
HKGNBBPO_00607 Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Sodium Deoxycholate (SDC) [class: Acid], Ethidium Bromide [class: Phenanthridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Acriflavine [class: Acridine] 87.3 2.1e-224 1 457 1.0000 1.0000 experiment
HKGNBBPO_00615 Chlorhexidine [class: Biguanides] 89.6 3.5e-104 1 193 1.0000 0.8616 experiment
HKGNBBPO_00615 Selenium (Se), Hydrogen Peroxide (H2O2) [class: Peroxides] 89.6 3.5e-104 1 193 1.0000 0.8616 experiment
HKGNBBPO_00669 Tellurium (Te), Proflavin [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Crystal Violet [class: Triarylmethane], Dequalinium [class: Quaternary Ammonium Compounds (QACs)], Methyl Viologen [class: Paraquat] 77.5 4.5e-144 9 332 0.9701 0.9818 experiment
HKGNBBPO_00670 Tellurium (Te), Proflavin [class: Acridine] 75.5 4.4e-86 1 196 0.9899 0.9949 experiment
HKGNBBPO_00737 Acriflavine [class: Acridine], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamindine], Hoechst 33342 [class: Bisbenzimide], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Methyl Viologen [class: Paraquat], Ethidium Bromide [class: Phenanthridine], Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)] 99.8 1.6e-254 1 499 1.0000 1.0000 experiment
HKGNBBPO_00746 Methyl Viologen [class: Paraquat] 76 4.9e-126 1 292 1.0000 0.9966 experiment
HKGNBBPO_00993 Cyclohexane [class: Cycloalkane], Diphenyl Ether [class: Phenyl], n-hexane [class: Alkane] 84 6.7e-68 1 144 1.0000 1.0000 experiment
HKGNBBPO_00994 Cyclohexane [class: Cycloalkane], Diphenyl Ether [class: Phenyl], n-hexane [class: Alkane] 92.7 2.7e-65 1 124 1.0000 0.9764 experiment
NGINNMPJ_00039 Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Rhodamine 6G [class: Xanthene] 90.3 5.7e-250 1 484 1.0000 0.9798 prediction
NGINNMPJ_00054 Iron (Fe) 100 0 1 600 1.0000 1.0000 prediction
NGINNMPJ_00055 Iron (Fe) 99.8 0 1 600 1.0000 1.0000 prediction
NGINNMPJ_00077 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 81.5 4e-126 1 275 0.9615 0.9649 prediction
NGINNMPJ_00078 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 71.9 1.8e-91 5 239 0.8608 0.8672 prediction
NGINNMPJ_00079 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 73.9 4.1e-129 1 303 0.9967 0.9934 prediction
NGINNMPJ_00110 Cadmium (Cd), Hydrogen Peroxide (H2O2) [class: Peroxides], Hydrochloric acid (HCl) [class: Acid] 100 2.2e-36 1 74 1.0000 0.9136 prediction
NGINNMPJ_00131 Iron (Fe), Copper (Cu), Manganese (Mn) 78 2.1e-71 1 164 0.9939 0.9880 prediction
NGINNMPJ_00147 Copper (Cu) 71.2 2.3e-98 1 243 0.9838 0.9798 prediction
NGINNMPJ_00223 Chromium (Cr), Tellurium (Te), Selenium (Se) 76 8e-142 1 334 0.9940 0.9570 prediction
NGINNMPJ_00224 Zinc (Zn) 100 3.7e-134 1 261 1.0000 1.0000 prediction
NGINNMPJ_00225 Zinc (Zn) 100 1.6e-139 1 250 1.0000 1.0000 prediction
NGINNMPJ_00226 Zinc (Zn) 80.6 2.4e-143 1 319 1.0000 1.0000 prediction
NGINNMPJ_00262 Manganese (Mn), Magnesium (Mg), Methyl Viologen [class: Paraquat], Hydrogen Peroxide (H2O2) [class: Peroxides] 90.9 4.6e-94 1 187 0.9947 0.9947 prediction
NGINNMPJ_00286 Cadmium (Cd), Mercury (Hg) 100 4e-100 1 176 1.0000 0.9888 prediction
NGINNMPJ_00353 Cadmium (Cd), Hydrogen Peroxide (H2O2) [class: Peroxides] 98.9 1.3e-46 1 91 1.0000 1.0000 prediction
NGINNMPJ_00607 Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Sodium Deoxycholate (SDC) [class: Acid], Ethidium Bromide [class: Phenanthridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Acriflavine [class: Acridine] 90.2 9.6e-231 1 457 1.0022 1.0000 prediction
NGINNMPJ_00615 Hydrogen Peroxide (H2O2) [class: Peroxides] 99.5 2.5e-111 1 193 1.0000 1.0000 prediction
NGINNMPJ_00669 Tellurium (Te), Proflavin [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Crystal Violet [class: Triarylmethane], Dequalinium [class: Quaternary Ammonium Compounds (QACs)], Methyl Viologen [class: Paraquat] 77.7 2.2e-147 1 332 0.9940 0.9940 prediction
NGINNMPJ_00670 Tellurium (Te), Proflavin [class: Acridine] 81.4 1.7e-91 5 198 0.9798 0.9848 prediction
NGINNMPJ_00737 Acriflavine [class: Acridine], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamindine], Hoechst 33342 [class: Bisbenzimide], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Methyl Viologen [class: Paraquat], Ethidium Bromide [class: Phenanthridine], Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)] 100 9.8e-253 1 499 1.0000 1.0000 prediction
NGINNMPJ_00746 Methyl Viologen [class: Paraquat] 76.7 5.9e-125 1 292 1.0000 0.9966 prediction
NGINNMPJ_00781 Hydrogen Peroxide (H2O2) [class: Peroxides] 99.3 2e-72 1 134 1.0000 1.0000 prediction
NGINNMPJ_00993 Cyclohexane [class: Cycloalkane], Diphenyl Ether [class: Phenyl], n-hexane [class: Alkane] 100 3.5e-78 1 144 1.0000 0.9863 prediction
HKGNBBPO_00039 Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Rhodamine 6G [class: Xanthene] 90.3 5.7e-250 1 484 1.0000 0.9798 prediction
HKGNBBPO_00054 Iron (Fe) 100 0 1 600 1.0000 1.0000 prediction
HKGNBBPO_00055 Iron (Fe) 99.8 0 1 600 1.0000 1.0000 prediction
HKGNBBPO_00077 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 81.5 4e-126 1 275 0.9615 0.9649 prediction
HKGNBBPO_00078 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 71.9 1.8e-91 5 239 0.8608 0.8672 prediction
HKGNBBPO_00079 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 73.9 4.1e-129 1 303 0.9967 0.9934 prediction
HKGNBBPO_00110 Cadmium (Cd), Hydrogen Peroxide (H2O2) [class: Peroxides], Hydrochloric acid (HCl) [class: Acid] 100 2.2e-36 1 74 1.0000 0.9136 prediction
HKGNBBPO_00131 Iron (Fe), Copper (Cu), Manganese (Mn) 78 2.1e-71 1 164 0.9939 0.9880 prediction
HKGNBBPO_00147 Copper (Cu) 71.2 2.3e-98 1 243 0.9838 0.9798 prediction
HKGNBBPO_00223 Chromium (Cr), Tellurium (Te), Selenium (Se) 76 8e-142 1 334 0.9940 0.9570 prediction
HKGNBBPO_00224 Zinc (Zn) 100 3.7e-134 1 261 1.0000 1.0000 prediction
HKGNBBPO_00225 Zinc (Zn) 100 1.6e-139 1 250 1.0000 1.0000 prediction
HKGNBBPO_00226 Zinc (Zn) 80.6 2.4e-143 1 319 1.0000 1.0000 prediction
HKGNBBPO_00262 Manganese (Mn), Magnesium (Mg), Methyl Viologen [class: Paraquat], Hydrogen Peroxide (H2O2) [class: Peroxides] 90.9 4.6e-94 1 187 0.9947 0.9947 prediction
HKGNBBPO_00286 Cadmium (Cd), Mercury (Hg) 100 4e-100 1 176 1.0000 0.9888 prediction
HKGNBBPO_00353 Cadmium (Cd), Hydrogen Peroxide (H2O2) [class: Peroxides] 98.9 1.3e-46 1 91 1.0000 1.0000 prediction
HKGNBBPO_00607 Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Sodium Deoxycholate (SDC) [class: Acid], Ethidium Bromide [class: Phenanthridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Acriflavine [class: Acridine] 90.2 9.6e-231 1 457 1.0022 1.0000 prediction
HKGNBBPO_00615 Hydrogen Peroxide (H2O2) [class: Peroxides] 99.5 2.5e-111 1 193 1.0000 1.0000 prediction
HKGNBBPO_00669 Tellurium (Te), Proflavin [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Crystal Violet [class: Triarylmethane], Dequalinium [class: Quaternary Ammonium Compounds (QACs)], Methyl Viologen [class: Paraquat] 77.7 2.2e-147 1 332 0.9940 0.9940 prediction
HKGNBBPO_00670 Tellurium (Te), Proflavin [class: Acridine] 81.4 1.7e-91 5 198 0.9798 0.9848 prediction
HKGNBBPO_00737 Acriflavine [class: Acridine], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamindine], Hoechst 33342 [class: Bisbenzimide], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Methyl Viologen [class: Paraquat], Ethidium Bromide [class: Phenanthridine], Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)] 100 9.8e-253 1 499 1.0000 1.0000 prediction
HKGNBBPO_00746 Methyl Viologen [class: Paraquat] 76.7 5.9e-125 1 292 1.0000 0.9966 prediction
HKGNBBPO_00781 Hydrogen Peroxide (H2O2) [class: Peroxides] 99.3 2e-72 1 134 1.0000 1.0000 prediction
HKGNBBPO_00993 Cyclohexane [class: Cycloalkane], Diphenyl Ether [class: Phenyl], n-hexane [class: Alkane] 100 3.5e-78 1 144 1.0000 0.9863 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
NGINNMPJ_00039 ARO:3001327 82.8 2.2e-288 1 470 0.9711 0.9916 fluoroquinolone antibiotic multidrug and toxic compound extrusion (MATE) transporter antibiotic efflux
NGINNMPJ_00393 ARO:3000676 89.6 9.77e-80 1 135 1.0000 0.9854 macrolide antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
NGINNMPJ_00993 ARO:3003378 84 3.48e-86 1 144 1.0000 1.0000 fluoroquinolone antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump antibiotic target alteration
NGINNMPJ_00994 ARO:3000263 93.5 9.79e-84 1 123 0.9919 0.9685 fluoroquinolone antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump antibiotic efflux
NGINNMPJ_01014 ARO:3001059 100 3.18e-202 1 286 1.0000 1.0000 cephalosporin SHV beta-lactamase antibiotic inactivation
HKGNBBPO_00039 ARO:3001327 82.8 2.2e-288 1 470 0.9711 0.9916 fluoroquinolone antibiotic multidrug and toxic compound extrusion (MATE) transporter antibiotic efflux
HKGNBBPO_00393 ARO:3000676 89.6 9.77e-80 1 135 1.0000 0.9854 macrolide antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
HKGNBBPO_00993 ARO:3003378 84 3.48e-86 1 144 1.0000 1.0000 fluoroquinolone antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump antibiotic target alteration
HKGNBBPO_00994 ARO:3000263 93.5 9.79e-84 1 123 0.9919 0.9685 fluoroquinolone antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump antibiotic efflux
HKGNBBPO_01014 ARO:3001059 100 3.18e-202 1 286 1.0000 1.0000 cephalosporin SHV beta-lactamase antibiotic inactivation






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
NGINNMPJ_00024 PHI:10111 STM14_RS07760 (orf245) 90.6 1.1e-12 39 70 0.4211 0.9347 eudicots infection hypothetical protein reduced virulence
NGINNMPJ_00036 PHI:12254 nac 70.8 1.3e-117 1 305 1.0000 1.0000 monocots Stewart's wilt; leaf blight (maize) nitrogen assimilation transcriptional regulator unaffected pathogenicity
NGINNMPJ_00047 PHI:4955 psn 99.9 0 1 673 1.0000 1.0000 rodents pneumonic plague iron binding unaffected pathogenicity
NGINNMPJ_00048 PHI:11277 ybtE 99.6 1.8e-303 1 525 1.0000 1.0000 primates infection yersiniabactin reduced virulence
NGINNMPJ_00052 PHI:11910 irp2 99.9 0 1 2035 1.0000 1.0000 rodents pneumonic plague yersiniabactin biosynthetic protein increased virulence (hypervirulence)
NGINNMPJ_00054 PHI:6912 ybtP 99.6 0 31 600 0.9500 1.0000 rodents urinary tract infection ATP binding cassette protein reduced virulence
NGINNMPJ_00055 PHI:6913 ybtQ 99.7 0 1 600 1.0000 1.0000 rodents urinary tract infection ATP binding cassette protein reduced virulence
NGINNMPJ_00056 PHI:11911 ybtX 98.1 7.8e-225 1 426 1.0000 0.9122 rodents pneumonic plague inner membrane protein, membrane permease reduced virulence
NGINNMPJ_00057 PHI:6653 ybtS 98.7 2.9e-176 1 307 0.9777 0.7074 rodents pneumonia isochorismate synthase/isochorismate-pyruvate lyase reduced virulence
NGINNMPJ_00077 PHI:10084 STM14_RS15355 77.7 8.9e-124 1 283 0.9895 0.9895 eudicots infection iron ABC transporter permease unaffected pathogenicity
NGINNMPJ_00079 PHI:10082 STM14_RS15345 73.3 5.7e-129 1 303 0.9967 0.9902 eudicots infection manganese/iron ABC transporter ATP-binding protein unaffected pathogenicity
NGINNMPJ_00094 PHI:12254 nac 75.7 1.4e-122 1 305 1.0000 1.0000 monocots Stewart's wilt; leaf blight (maize) nitrogen assimilation transcriptional regulator unaffected pathogenicity
NGINNMPJ_00095 PHI:10578 PccS1_002702 72.9 6.3e-131 1 316 1.0000 1.0000 monocots soft rot transcriptional regulator, LysR family unaffected pathogenicity
NGINNMPJ_00121 PHI:560 sirA 93.6 8.6e-111 1 218 1.0000 1.0000 rodents gastroenteritis None reduced virulence
NGINNMPJ_00224 PHI:11006 znuB 92.7 2.5e-125 1 261 1.0000 1.0000 even-toed ungulates infection Zn(2(+)) ABC transporter membrane subunit reduced virulence
NGINNMPJ_00225 PHI:11007 znuC 90.4 2.3e-128 1 250 1.0000 0.9960 even-toed ungulates infection Zn(2(+)) ABC transporter ATP binding subunit reduced virulence
NGINNMPJ_00226 PHI:11005 znuA 76.4 4.7e-134 6 319 0.9843 1.0000 even-toed ungulates infection Zn(2(+)) ABC transporter periplasmic binding reduced virulence
NGINNMPJ_00227 PHI:4185 ypo2062 74.6 5.3e-184 22 439 0.9522 1.0000 rodents bubonic plague putative DNA binding protein reduced virulence
NGINNMPJ_00232 PHI:11150 edd 74.5 2.2e-265 1 601 0.9967 0.9804 eudicots soft rot (potato); blackleg disease (potato) phosphogluconate dehydratase unaffected pathogenicity
NGINNMPJ_00233 PHI:11149 eda 85.9 3.3e-99 1 213 1.0000 0.9953 eudicots soft rot (potato); blackleg disease (potato) 2-keto-3-deoxy-6-phosphogluconate aldolase reduced virulence
NGINNMPJ_00234 PHI:8653 purT 84.4 1.5e-185 1 392 1.0000 1.0000 primates infection formate-dependent phosphoribosylglycinamide formyltransferase unaffected pathogenicity
NGINNMPJ_00252 PHI:8783 ProQ 84.7 1.9e-97 1 225 1.0000 1.0000 primates salmonellosis RNA chaperone reduced virulence
NGINNMPJ_00253 PHI:9896 Prc 89.9 0 1 682 1.0000 1.0000 rodents urinary tract infection tail-specific protease reduced virulence
NGINNMPJ_00254 PHI:124002 yebE 92.2 7.2e-145 1 294 1.0000 1.0000 rodents colitis cpx-regulated gene unaffected pathogenicity
NGINNMPJ_00256 PHI:4175 kdgR 88.6 4.2e-128 1 263 1.0000 1.0000 eudicots soft rot virulence negative regulators unaffected pathogenicity
NGINNMPJ_00259 PHI:7262 cspC 100 1.1e-35 1 69 1.0000 1.0000 primates salmonellosis cold shock protein reduced virulence
NGINNMPJ_00270 PHI:9496 yeaB 84 3.1e-88 6 192 0.9740 0.9740 rodents infection RNA methyltransferase reduced virulence
NGINNMPJ_00277 PHI:4108 fadD 71 5.9e-236 14 571 0.9755 0.9876 rabbits and hares cholera encoding a long-chain fatty acyl coenzyme A (acyl-CoA) ligase reduced virulence
NGINNMPJ_00288 PHI:11407 gntR 100 8.2e-139 1 239 1.0000 1.0000 rodents pneumonia fatty acid metabolism regulator reduced virulence
NGINNMPJ_00296 PHI:10199 treA 74.3 2.3e-259 13 579 0.9759 0.9841 birds urinary tract infection periplasmic trehalase reduced virulence
NGINNMPJ_00347 PHI:7082 tssE-2 75 2.8e-57 4 147 0.9796 0.9600 eudicots fire blight T6SS-3 component reduced virulence
NGINNMPJ_00377 PHI:124167 narL 94.9 1.2e-109 1 216 1.0000 1.0000 rodents neonatal meningitis two-component system reduced virulence
NGINNMPJ_00378 PHI:124166 narX 78.5 5e-262 1 590 0.9966 0.9866 rodents neonatal meningitis two-component system reduced virulence
NGINNMPJ_00379 PHI:123379 narK 88 1.6e-231 1 459 0.9935 0.9871 rodents salmonellosis nitrate/nitrite transporter reduced virulence
NGINNMPJ_00380 PHI:10512 narG 93.7 0 1 1247 1.0000 1.0000 rodents urinary tract infection respiratory nitrate reductase 1 alpha chain reduced virulence
NGINNMPJ_00381 PHI:10513 narH 93 5.5e-294 1 510 0.9980 0.9980 rodents urinary tract infection respiratory nitrate reductase 1 beta chain reduced virulence
NGINNMPJ_00382 PHI:10514 narJ 86.4 2.6e-113 1 235 0.9958 0.9958 rodents urinary tract infection nitrate reductase molybdenum cofactor assembly chaperone reduced virulence
NGINNMPJ_00383 PHI:10515 narI 91.1 2.8e-117 1 224 0.9956 0.9956 rodents urinary tract infection respiratory nitrate reductase 1 gamma chain reduced virulence
NGINNMPJ_00391 PHI:2679 hnr 83.7 6.7e-163 1 337 1.0000 1.0000 rodents food poisoning regulators of systemic infection reduced virulence
NGINNMPJ_00392 PHI:124019 GalU 94.9 1.5e-158 1 295 0.9833 0.9768 birds salmonellosis uridine diphosphate–glucose pyrophosphorylase reduced virulence
NGINNMPJ_00393 PHI:6097 hns 100 1.5e-68 1 135 1.0000 1.0000 rodents pneumonia pleiotropic regulator increased virulence (hypervirulence)
NGINNMPJ_00404 PHI:123208 clsA 95.1 5.1e-273 1 486 1.0000 1.0000 rodents salmonellosis cardiolipin synthase A unaffected pathogenicity
NGINNMPJ_00408 PHI:6651 tonB 98.8 3.8e-123 1 245 1.0000 1.0000 rodents pneumonia siderophores synthesis unaffected pathogenicity
NGINNMPJ_00420 PHI:124344 ihfA 100 1e-50 1 99 1.0000 1.0000 primates pneumonia integration host factor reduced virulence
NGINNMPJ_00457 PHI:6893 sufB 94.5 6.6e-284 1 495 1.0000 1.0000 rodents salmonellosis sulfur mobilization unaffected pathogenicity
NGINNMPJ_00458 PHI:10100 STM14_RS07710 (sufC) 91.5 1.4e-128 1 248 1.0000 1.0000 eudicots infection Fe-S cluster assembly ATPase reduced virulence
NGINNMPJ_00459 PHI:10101 STM14_RS07715 (sufD) 74.5 1.6e-182 1 424 1.0000 1.0000 eudicots infection Fe-S cluster assembly protein reduced virulence
NGINNMPJ_00460 PHI:10102 STM14_RS07720 (sufS) 80.8 5.4e-191 1 406 1.0000 1.0000 eudicots infection cysteine desulfurase reduced virulence
NGINNMPJ_00461 PHI:10103 STM14_RS07725 (ynhA/sufE) 80.4 1.5e-60 1 138 1.0000 1.0000 eudicots infection cysteine desulfuration protein reduced virulence
NGINNMPJ_00462 PHI:10104 STM14_RS07730 (ynhG) 74.5 1.3e-134 1 318 0.9695 0.9610 eudicots infection murein L,D-transpeptidase reduced virulence
NGINNMPJ_00463 PHI:10106 STM14_RS07740 (lpp) 97.4 5.2e-34 1 78 1.0000 1.0000 eudicots infection murein lipoprotein reduced virulence
NGINNMPJ_00464 PHI:10107 STM14_RS07745 (pykF) 96.2 2.6e-253 1 470 1.0000 1.0000 eudicots infection pyruvate kinase I reduced virulence
NGINNMPJ_00465 PHI:10118 STM14_RS07795 (orf70) 75 8.2e-23 1 68 0.9714 0.9714 eudicots infection hypothetical protein reduced virulence
NGINNMPJ_00516 PHI:7534 CcmA (VK055_1938) 97.7 2.5e-96 1 177 0.8551 0.9296 rodents pneumonia heme ABC exporter, ATP-binding protein unaffected pathogenicity
NGINNMPJ_00517 PHI:7534 CcmA (VK055_1938) 99.1 8.9e-108 1 219 1.0000 0.9296 rodents pneumonia heme ABC exporter, ATP-binding protein unaffected pathogenicity
NGINNMPJ_00615 PHI:11377 sodB 90.7 2.6e-103 1 193 1.0000 1.0000 moths salmonellosis cytoplasmic superoxide dismutase increased virulence (hypervirulence)
NGINNMPJ_00625 PHI:9809 SodCII 71.7 4.5e-70 1 173 1.0000 1.0000 rodents salmonellosis superoxide dismutase [Cu-Zn] 2 reduced virulence
NGINNMPJ_00629 PHI:2678 slyA 84 1.5e-63 1 144 1.0000 1.0000 rodents food poisoning regulators of systemic infection reduced virulence
NGINNMPJ_00633 PHI:2646 MliC 72 2.7e-42 13 119 0.8992 1.0000 birds colibacillosis; cellulitis; swollen head syndrome lysozyme inhibitor reduced virulence
NGINNMPJ_00648 PHI:4179 expI 78.6 2.7e-29 1 70 0.9859 0.9859 eudicots soft rot synthesis and perception of signaling molecules reduced virulence
NGINNMPJ_00666 PHI:10993 mdoD 84.5 6.4e-297 64 613 0.8958 0.9982 rodents infection glucans biosynthesis protein D unaffected pathogenicity
NGINNMPJ_00683 PHI:7225 ydcR 84.3 1.6e-226 1 470 1.0000 0.9895 rodents salmonellosis putative transcriptional regulator reduced virulence
NGINNMPJ_00731 PHI:10519 narV 82.3 4e-111 1 226 1.0000 1.0000 rodents urinary tract infection respiratory nitrate reductase 2 gamma chain reduced virulence
NGINNMPJ_00732 PHI:10518 narW 78.8 1.6e-102 1 231 1.0000 1.0000 rodents urinary tract infection probable nitrate reductase molybdenum cofactor assembly chaperone reduced virulence
NGINNMPJ_00733 PHI:10517 narY 88.3 4.9e-290 1 514 1.0000 1.0000 rodents urinary tract infection respiratory nitrate reductase 2 beta chain reduced virulence
NGINNMPJ_00734 PHI:10516 narZ 88 0 1 1246 1.0000 1.0000 rodents urinary tract infection respiratory nitrate reductase 2 alpha chain reduced virulence
NGINNMPJ_00735 PHI:123381 narU 83.2 5.6e-221 1 459 0.9978 0.9935 rodents salmonellosis nitrate/nitrite transporter unaffected pathogenicity
NGINNMPJ_00747 PHI:10997 fdnG 93.3 1.1e-106 1 195 1.0000 0.9833 rodents infection formate dehydrogenase, nitrate-inducible, major subunit unaffected pathogenicity
NGINNMPJ_00748 PHI:10997 fdnG 90.7 0 1 803 1.0000 0.9833 rodents infection formate dehydrogenase, nitrate-inducible, major subunit unaffected pathogenicity
NGINNMPJ_00798 PHI:3668 MgtC 70.9 3.5e-83 1 223 0.9867 0.9654 rodents food poisoning virulence protein effector (plant avirulence determinant)
NGINNMPJ_00800 PHI:11381 katG 82.8 0 1 725 1.0000 0.9986 moths salmonellosis catalase reduced virulence
NGINNMPJ_00883 PHI:11265 pgtP 90.9 4.5e-242 1 463 1.0000 1.0000 rodents infection phosphoglycerate transporter protein reduced virulence
NGINNMPJ_00994 PHI:5369 MarA 92.7 2.9e-63 1 124 1.0000 0.9764 rodents bacteremia transcriptional regulator reduced virulence
HKGNBBPO_00024 PHI:10111 STM14_RS07760 (orf245) 90.6 1.1e-12 39 70 0.4211 0.9347 eudicots infection hypothetical protein reduced virulence
HKGNBBPO_00036 PHI:12254 nac 70.8 1.3e-117 1 305 1.0000 1.0000 monocots Stewart's wilt; leaf blight (maize) nitrogen assimilation transcriptional regulator unaffected pathogenicity
HKGNBBPO_00047 PHI:4955 psn 99.9 0 1 673 1.0000 1.0000 rodents pneumonic plague iron binding unaffected pathogenicity
HKGNBBPO_00048 PHI:11277 ybtE 99.6 1.8e-303 1 525 1.0000 1.0000 primates infection yersiniabactin reduced virulence
HKGNBBPO_00052 PHI:11910 irp2 99.9 0 1 2035 1.0000 1.0000 rodents pneumonic plague yersiniabactin biosynthetic protein increased virulence (hypervirulence)
HKGNBBPO_00054 PHI:6912 ybtP 99.6 0 31 600 0.9500 1.0000 rodents urinary tract infection ATP binding cassette protein reduced virulence
HKGNBBPO_00055 PHI:6913 ybtQ 99.7 0 1 600 1.0000 1.0000 rodents urinary tract infection ATP binding cassette protein reduced virulence
HKGNBBPO_00056 PHI:11911 ybtX 98.1 7.8e-225 1 426 1.0000 0.9122 rodents pneumonic plague inner membrane protein, membrane permease reduced virulence
HKGNBBPO_00057 PHI:6653 ybtS 98.7 2.9e-176 1 307 0.9777 0.7074 rodents pneumonia isochorismate synthase/isochorismate-pyruvate lyase reduced virulence
HKGNBBPO_00077 PHI:10084 STM14_RS15355 77.7 8.9e-124 1 283 0.9895 0.9895 eudicots infection iron ABC transporter permease unaffected pathogenicity
HKGNBBPO_00079 PHI:10082 STM14_RS15345 73.3 5.7e-129 1 303 0.9967 0.9902 eudicots infection manganese/iron ABC transporter ATP-binding protein unaffected pathogenicity
HKGNBBPO_00094 PHI:12254 nac 75.7 1.4e-122 1 305 1.0000 1.0000 monocots Stewart's wilt; leaf blight (maize) nitrogen assimilation transcriptional regulator unaffected pathogenicity
HKGNBBPO_00095 PHI:10578 PccS1_002702 72.9 6.3e-131 1 316 1.0000 1.0000 monocots soft rot transcriptional regulator, LysR family unaffected pathogenicity
HKGNBBPO_00121 PHI:560 sirA 93.6 8.6e-111 1 218 1.0000 1.0000 rodents gastroenteritis None reduced virulence
HKGNBBPO_00224 PHI:11006 znuB 92.7 2.5e-125 1 261 1.0000 1.0000 even-toed ungulates infection Zn(2(+)) ABC transporter membrane subunit reduced virulence
HKGNBBPO_00225 PHI:11007 znuC 90.4 2.3e-128 1 250 1.0000 0.9960 even-toed ungulates infection Zn(2(+)) ABC transporter ATP binding subunit reduced virulence
HKGNBBPO_00226 PHI:11005 znuA 76.4 4.7e-134 6 319 0.9843 1.0000 even-toed ungulates infection Zn(2(+)) ABC transporter periplasmic binding reduced virulence
HKGNBBPO_00227 PHI:4185 ypo2062 74.6 5.3e-184 22 439 0.9522 1.0000 rodents bubonic plague putative DNA binding protein reduced virulence
HKGNBBPO_00232 PHI:11150 edd 74.5 2.2e-265 1 601 0.9967 0.9804 eudicots soft rot (potato); blackleg disease (potato) phosphogluconate dehydratase unaffected pathogenicity
HKGNBBPO_00233 PHI:11149 eda 85.9 3.3e-99 1 213 1.0000 0.9953 eudicots soft rot (potato); blackleg disease (potato) 2-keto-3-deoxy-6-phosphogluconate aldolase reduced virulence
HKGNBBPO_00234 PHI:8653 purT 84.4 1.5e-185 1 392 1.0000 1.0000 primates infection formate-dependent phosphoribosylglycinamide formyltransferase unaffected pathogenicity
HKGNBBPO_00252 PHI:8783 ProQ 84.7 1.9e-97 1 225 1.0000 1.0000 primates salmonellosis RNA chaperone reduced virulence
HKGNBBPO_00253 PHI:9896 Prc 89.9 0 1 682 1.0000 1.0000 rodents urinary tract infection tail-specific protease reduced virulence
HKGNBBPO_00254 PHI:124002 yebE 92.2 7.2e-145 1 294 1.0000 1.0000 rodents colitis cpx-regulated gene unaffected pathogenicity
HKGNBBPO_00256 PHI:4175 kdgR 88.6 4.2e-128 1 263 1.0000 1.0000 eudicots soft rot virulence negative regulators unaffected pathogenicity
HKGNBBPO_00259 PHI:7262 cspC 100 1.1e-35 1 69 1.0000 1.0000 primates salmonellosis cold shock protein reduced virulence
HKGNBBPO_00270 PHI:9496 yeaB 84 3.1e-88 6 192 0.9740 0.9740 rodents infection RNA methyltransferase reduced virulence
HKGNBBPO_00277 PHI:4108 fadD 71 5.9e-236 14 571 0.9755 0.9876 rabbits and hares cholera encoding a long-chain fatty acyl coenzyme A (acyl-CoA) ligase reduced virulence
HKGNBBPO_00288 PHI:11407 gntR 100 8.2e-139 1 239 1.0000 1.0000 rodents pneumonia fatty acid metabolism regulator reduced virulence
HKGNBBPO_00296 PHI:10199 treA 74.3 2.3e-259 13 579 0.9759 0.9841 birds urinary tract infection periplasmic trehalase reduced virulence
HKGNBBPO_00347 PHI:7082 tssE-2 75 2.8e-57 4 147 0.9796 0.9600 eudicots fire blight T6SS-3 component reduced virulence
HKGNBBPO_00377 PHI:124167 narL 94.9 1.2e-109 1 216 1.0000 1.0000 rodents neonatal meningitis two-component system reduced virulence
HKGNBBPO_00378 PHI:124166 narX 78.5 5e-262 1 590 0.9966 0.9866 rodents neonatal meningitis two-component system reduced virulence
HKGNBBPO_00379 PHI:123379 narK 88 1.6e-231 1 459 0.9935 0.9871 rodents salmonellosis nitrate/nitrite transporter reduced virulence
HKGNBBPO_00380 PHI:10512 narG 93.7 0 1 1247 1.0000 1.0000 rodents urinary tract infection respiratory nitrate reductase 1 alpha chain reduced virulence
HKGNBBPO_00381 PHI:10513 narH 93 5.5e-294 1 510 0.9980 0.9980 rodents urinary tract infection respiratory nitrate reductase 1 beta chain reduced virulence
HKGNBBPO_00382 PHI:10514 narJ 86.4 2.6e-113 1 235 0.9958 0.9958 rodents urinary tract infection nitrate reductase molybdenum cofactor assembly chaperone reduced virulence
HKGNBBPO_00383 PHI:10515 narI 91.1 2.8e-117 1 224 0.9956 0.9956 rodents urinary tract infection respiratory nitrate reductase 1 gamma chain reduced virulence
HKGNBBPO_00391 PHI:2679 hnr 83.7 6.7e-163 1 337 1.0000 1.0000 rodents food poisoning regulators of systemic infection reduced virulence
HKGNBBPO_00392 PHI:124019 GalU 94.9 1.5e-158 1 295 0.9833 0.9768 birds salmonellosis uridine diphosphate–glucose pyrophosphorylase reduced virulence
HKGNBBPO_00393 PHI:6097 hns 100 1.5e-68 1 135 1.0000 1.0000 rodents pneumonia pleiotropic regulator increased virulence (hypervirulence)
HKGNBBPO_00404 PHI:123208 clsA 95.1 5.1e-273 1 486 1.0000 1.0000 rodents salmonellosis cardiolipin synthase A unaffected pathogenicity
HKGNBBPO_00408 PHI:6651 tonB 98.8 3.8e-123 1 245 1.0000 1.0000 rodents pneumonia siderophores synthesis unaffected pathogenicity
HKGNBBPO_00420 PHI:124344 ihfA 100 1e-50 1 99 1.0000 1.0000 primates pneumonia integration host factor reduced virulence
HKGNBBPO_00457 PHI:6893 sufB 94.5 6.6e-284 1 495 1.0000 1.0000 rodents salmonellosis sulfur mobilization unaffected pathogenicity
HKGNBBPO_00458 PHI:10100 STM14_RS07710 (sufC) 91.5 1.4e-128 1 248 1.0000 1.0000 eudicots infection Fe-S cluster assembly ATPase reduced virulence
HKGNBBPO_00459 PHI:10101 STM14_RS07715 (sufD) 74.5 1.6e-182 1 424 1.0000 1.0000 eudicots infection Fe-S cluster assembly protein reduced virulence
HKGNBBPO_00460 PHI:10102 STM14_RS07720 (sufS) 80.8 5.4e-191 1 406 1.0000 1.0000 eudicots infection cysteine desulfurase reduced virulence
HKGNBBPO_00461 PHI:10103 STM14_RS07725 (ynhA/sufE) 80.4 1.5e-60 1 138 1.0000 1.0000 eudicots infection cysteine desulfuration protein reduced virulence
HKGNBBPO_00462 PHI:10104 STM14_RS07730 (ynhG) 74.5 1.3e-134 1 318 0.9695 0.9610 eudicots infection murein L,D-transpeptidase reduced virulence
HKGNBBPO_00463 PHI:10106 STM14_RS07740 (lpp) 97.4 5.2e-34 1 78 1.0000 1.0000 eudicots infection murein lipoprotein reduced virulence
HKGNBBPO_00464 PHI:10107 STM14_RS07745 (pykF) 96.2 2.6e-253 1 470 1.0000 1.0000 eudicots infection pyruvate kinase I reduced virulence
HKGNBBPO_00465 PHI:10118 STM14_RS07795 (orf70) 75 8.2e-23 1 68 0.9714 0.9714 eudicots infection hypothetical protein reduced virulence
HKGNBBPO_00516 PHI:7534 CcmA (VK055_1938) 97.7 2.5e-96 1 177 0.8551 0.9296 rodents pneumonia heme ABC exporter, ATP-binding protein unaffected pathogenicity
HKGNBBPO_00517 PHI:7534 CcmA (VK055_1938) 99.1 8.9e-108 1 219 1.0000 0.9296 rodents pneumonia heme ABC exporter, ATP-binding protein unaffected pathogenicity
HKGNBBPO_00615 PHI:11377 sodB 90.7 2.6e-103 1 193 1.0000 1.0000 moths salmonellosis cytoplasmic superoxide dismutase increased virulence (hypervirulence)
HKGNBBPO_00625 PHI:9809 SodCII 71.7 4.5e-70 1 173 1.0000 1.0000 rodents salmonellosis superoxide dismutase [Cu-Zn] 2 reduced virulence
HKGNBBPO_00629 PHI:2678 slyA 84 1.5e-63 1 144 1.0000 1.0000 rodents food poisoning regulators of systemic infection reduced virulence
HKGNBBPO_00633 PHI:2646 MliC 72 2.7e-42 13 119 0.8992 1.0000 birds colibacillosis; cellulitis; swollen head syndrome lysozyme inhibitor reduced virulence
HKGNBBPO_00648 PHI:4179 expI 78.6 2.7e-29 1 70 0.9859 0.9859 eudicots soft rot synthesis and perception of signaling molecules reduced virulence
HKGNBBPO_00666 PHI:10993 mdoD 84.5 6.4e-297 64 613 0.8958 0.9982 rodents infection glucans biosynthesis protein D unaffected pathogenicity
HKGNBBPO_00683 PHI:7225 ydcR 84.3 1.6e-226 1 470 1.0000 0.9895 rodents salmonellosis putative transcriptional regulator reduced virulence
HKGNBBPO_00731 PHI:10519 narV 82.3 4e-111 1 226 1.0000 1.0000 rodents urinary tract infection respiratory nitrate reductase 2 gamma chain reduced virulence
HKGNBBPO_00732 PHI:10518 narW 78.8 1.6e-102 1 231 1.0000 1.0000 rodents urinary tract infection probable nitrate reductase molybdenum cofactor assembly chaperone reduced virulence
HKGNBBPO_00733 PHI:10517 narY 88.3 4.9e-290 1 514 1.0000 1.0000 rodents urinary tract infection respiratory nitrate reductase 2 beta chain reduced virulence
HKGNBBPO_00734 PHI:10516 narZ 88 0 1 1246 1.0000 1.0000 rodents urinary tract infection respiratory nitrate reductase 2 alpha chain reduced virulence
HKGNBBPO_00735 PHI:123381 narU 83.2 5.6e-221 1 459 0.9978 0.9935 rodents salmonellosis nitrate/nitrite transporter unaffected pathogenicity
HKGNBBPO_00747 PHI:10997 fdnG 93.3 1.1e-106 1 195 1.0000 0.9833 rodents infection formate dehydrogenase, nitrate-inducible, major subunit unaffected pathogenicity
HKGNBBPO_00748 PHI:10997 fdnG 90.7 0 1 803 1.0000 0.9833 rodents infection formate dehydrogenase, nitrate-inducible, major subunit unaffected pathogenicity
HKGNBBPO_00798 PHI:3668 MgtC 70.9 3.5e-83 1 223 0.9867 0.9654 rodents food poisoning virulence protein effector (plant avirulence determinant)
HKGNBBPO_00800 PHI:11381 katG 82.8 0 1 725 1.0000 0.9986 moths salmonellosis catalase reduced virulence
HKGNBBPO_00883 PHI:11265 pgtP 90.9 4.5e-242 1 463 1.0000 1.0000 rodents infection phosphoglycerate transporter protein reduced virulence
HKGNBBPO_00994 PHI:5369 MarA 92.7 2.9e-63 1 124 1.0000 0.9764 rodents bacteremia transcriptional regulator reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
NGINNMPJ_00044 ULJ14112.1|GT0 100 8.24e-245 1 350 1 1
NGINNMPJ_00114 QBH46053.1|GH13_5 100 0 1 495 1 1
NGINNMPJ_00141 QBD90328.1|GT20 100 0 1 474 1 1
NGINNMPJ_00144 AWA51529.1|GH105 100 8.52e-289 1 379 1 1
NGINNMPJ_00185 QBH57814.1|GH24 100 1.35e-129 1 176 1 1
NGINNMPJ_00202 QBH45975.1|GH23 100 0 1 633 1 0.9664
NGINNMPJ_00227 QAV78832.1|CBM50 100 3.04000024676492e-317 1 439 1 1
NGINNMPJ_00293 BAB35111.2|GH23 72.5 2.22e-157 1 302 0.9934 0.9934
NGINNMPJ_00294 QJK43886.1|GH23 100 4.58e-148 1 203 1 1
NGINNMPJ_00296 QBH56017.1|GH37 100 0 1 581 1 1
NGINNMPJ_00649 ATM56419.1|GH1 100 0 1 456 1 1
NGINNMPJ_00723 AZB76852.1|GH78 100 0 1 522 1 1
NGINNMPJ_00776 AMV51773.1|GH13_16 100 0 1 541 1 1
NGINNMPJ_00791 QBH45422.1|GH78 100 0 1 870 1 1
NGINNMPJ_00835 QXX04187.1|CE4 100 7.01e-244 1 310 1 1
NGINNMPJ_00871 QSS26985.1|GH0 100 0 1 751 1 1
NGINNMPJ_00924 QJJ27774.1|GH4 100 0 1 442 1 1
NGINNMPJ_00986 QJJ64718.1|GH33 100 2.31e-302 1 388 1 1
NGINNMPJ_01010 QET19412.1|GH2 100 0 1 1035 1 1
HKGNBBPO_00044 ULJ14112.1|GT0 100 8.24e-245 1 350 1 1
HKGNBBPO_00114 QBH46053.1|GH13_5 100 0 1 495 1 1
HKGNBBPO_00141 QBD90328.1|GT20 100 0 1 474 1 1
HKGNBBPO_00144 AWA51529.1|GH105 100 8.52e-289 1 379 1 1
HKGNBBPO_00185 QBH57814.1|GH24 100 1.35e-129 1 176 1 1
HKGNBBPO_00202 QBH45975.1|GH23 100 0 1 633 1 0.9664
HKGNBBPO_00227 QAV78832.1|CBM50 100 3.04000024676492e-317 1 439 1 1
HKGNBBPO_00293 BAB35111.2|GH23 72.5 2.22e-157 1 302 0.9934 0.9934
HKGNBBPO_00294 QJK43886.1|GH23 100 4.58e-148 1 203 1 1
HKGNBBPO_00296 QBH56017.1|GH37 100 0 1 581 1 1
HKGNBBPO_00649 ATM56419.1|GH1 100 0 1 456 1 1
HKGNBBPO_00723 AZB76852.1|GH78 100 0 1 522 1 1
HKGNBBPO_00776 AMV51773.1|GH13_16 100 0 1 541 1 1
HKGNBBPO_00791 QBH45422.1|GH78 100 0 1 870 1 1
HKGNBBPO_00835 QXX04187.1|CE4 100 7.01e-244 1 310 1 1
HKGNBBPO_00871 QSS26985.1|GH0 100 0 1 751 1 1
HKGNBBPO_00924 QJJ27774.1|GH4 100 0 1 442 1 1
HKGNBBPO_00986 QJJ64718.1|GH33 100 2.31e-302 1 388 1 1
HKGNBBPO_01010 QET19412.1|GH2 100 0 1 1035 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
NGINNMPJ_00023 1.A.13.5.1 99 5.8e-114 1 197 1.0000 0.7817 1 Channels/Pores 1.A α-Type Channels 1.A.13 The Epithelial Chloride Channel (E-ClC) Family
NGINNMPJ_00039 2.A.66.1.23 99.4 5.7e-272 1 484 1.0000 0.9778 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.66 The Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily
NGINNMPJ_00043 2.A.1.6.6 99.1 4.8e-246 1 438 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
NGINNMPJ_00047 1.B.14.8.7 99.1 0 1 673 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.14 The Outer Membrane Receptor (OMR) Family
NGINNMPJ_00054 3.A.1.21.1 99.8 0 1 600 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00055 3.A.1.21.1 99.7 0 1 600 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00056 2.A.1.57.3 97.2 6.2e-222 1 426 1.0000 0.9122 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
NGINNMPJ_00077 3.A.1.15.7 77.7 2e-123 1 283 0.9895 0.9279 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00079 3.A.1.15.7 73.3 1.3e-128 1 303 0.9967 0.9902 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00102 1.B.1.1.27 76.1 1.4e-169 1 381 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.1 The General Bacterial Porin (GBP) Family
NGINNMPJ_00107 2.A.7.3.22 80.2 2.3e-130 1 298 0.9835 0.9739 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.7 The Drug/Metabolite Transporter (DMT) Superfamily
NGINNMPJ_00115 3.A.1.3.10 89.8 3.7e-129 1 255 1.0000 1.0200 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00117 3.A.1.3.10 93.7 1.4e-111 1 222 1.0000 0.8880 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00118 3.A.1.3.10 91.2 9.2e-125 1 250 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00129 2.A.42.1.1 78.9 3.6e-165 1 380 1.0000 0.9429 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.42 The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family
NGINNMPJ_00137 3.A.1.2.2 91.7 1.7e-174 1 326 1.0000 0.9939 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00138 3.A.1.2.2 87.3 2.4e-257 1 504 1.0000 1.5366 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00139 3.A.1.2.2 92.3 1.8e-160 1 324 0.9939 0.9939 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00143 2.A.2.5.2 81.2 7.1e-236 1 512 0.9715 0.9865 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.2 The Glycoside-Pentoside-Hexuronide (GPH):Cation Symporter Family
NGINNMPJ_00224 3.A.1.15.5 92.7 5.6e-125 1 261 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00225 3.A.1.15.5 90.4 5.2e-128 1 250 1.0000 0.9579 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00226 3.A.1.15.5 76.4 1.1e-133 6 319 0.9843 1.1877 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00249 9.A.69.1.2 81.3 0 1 877 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.A Recognized transporters of unknown biochemical mechanism 9.A.69 The Intermembrane Phospholipid Translocase (IMPL-T) Family
NGINNMPJ_00253 9.B.174.1.2 89.9 0 1 682 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.174 The Two Tunnel Gated C-terminal Processing Protease (CTP) Family
NGINNMPJ_00254 9.B.1.1.6 91.5 1e-143 1 294 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.1 The Integral Membrane CAAX Protease (CAAX Protease) Family
NGINNMPJ_00255 2.A.1.3.17 79.8 2.2e-201 1 455 0.9978 0.9956 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
NGINNMPJ_00262 2.A.107.1.1 82.4 5.7e-87 1 188 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.107 The MntP Mn2+ exporter (MntP) Family
NGINNMPJ_00264 4.A.6.1.1 92.2 1.4e-148 1 283 1.0000 0.9895 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family
NGINNMPJ_00265 4.A.6.1.1 94 1.2e-130 1 266 1.0000 0.9301 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family
NGINNMPJ_00266 4.A.6.1.1 95.4 9.3e-170 1 323 1.0000 1.1294 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family
NGINNMPJ_00277 4.C.1.1.4 93 4.7e-310 12 571 0.9790 0.9982 4 Group Translocators 4.C Acyl CoA ligase-coupled transporters 4.C.1 The Fatty Acid Group Translocation (FAT) Family
NGINNMPJ_00286 5.A.2.1.1 79.5 8.6e-85 1 176 1.0000 1.0000 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.2 The Disulfide Bond Oxidoreductase B (DsbB) Family
NGINNMPJ_00287 2.A.34.1.1 85.4 5.4e-245 61 572 0.8889 0.9981 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.34 The NhaB Na+:H+ Antiporter (NhaB) Family
NGINNMPJ_00292 2.A.36.6.11 88.7 7.7e-292 1 577 1.0000 0.9983 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.36 The Monovalent Cation:Proton Antiporter-1 (CPA1) Family
NGINNMPJ_00306 2.A.42.2.2 91 3.3e-226 1 443 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.42 The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family
NGINNMPJ_00318 2.A.1.6.1 99.8 6.9e-229 13 431 0.9722 0.9437 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
NGINNMPJ_00355 2.A.53.3.11 89.3 9.6e-276 1 550 1.0000 0.9839 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.53 The Sulfate Permease (SulP) Family
NGINNMPJ_00358 1.B.46.1.1 82.1 1.6e-98 3 203 0.9901 0.9710 1 Channels/Pores 1.B β-Barrel Porins 1.B.46 The Outer Membrane LolAB Lipoprotein Insertion Apparatus (LolAB) Family
NGINNMPJ_00365 2.A.19.1.1 92.9 4.9e-183 1 366 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.19 The Ca2+:Cation Antiporter (CaCA) Family
NGINNMPJ_00379 2.A.1.8.1 86.5 6.7e-230 1 459 0.9935 0.9914 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
NGINNMPJ_00380 5.A.3.1.1 93.7 0 1 1247 1.0000 5.5422 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
NGINNMPJ_00381 5.A.3.1.1 93 1.2e-293 1 510 0.9980 2.2711 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
NGINNMPJ_00383 5.A.3.1.1 91.1 6.4e-117 1 224 0.9956 0.9956 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
NGINNMPJ_00396 2.A.95.1.7 88.8 3.3e-99 1 215 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.95 The 6 TMS Neutral Amino Acid Transporter (NAAT) Family
NGINNMPJ_00397 3.A.1.5.41 84 1.4e-279 1 544 1.0000 1.0150 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00408 2.C.1.1.1 75.7 7.5e-87 1 241 0.9837 0.9791 2 Electrochemical Potential-driven Transporters 2.C Ion-gradient-driven energizers 2.C.1 The TonB-ExbB-ExbD/TolA-TolQ-TolR Outer Membrane Receptor Energizers and Stabilizers (TonB/TolA) Family
NGINNMPJ_00412 1.B.75.1.3 84.5 1.2e-124 1 252 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.75 The DUF481 Putative Beta Barrel Porin (DUF481) Family
NGINNMPJ_00425 3.A.1.13.1 83.3 2.9e-150 1 324 0.9878 1.2180 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00435 2.A.86.2.1 78.9 5.3e-161 1 370 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.86 The Autoinducer-2 Exporter (AI-2E) Family (Formerly the PerM Family, TC #9.B.22)
NGINNMPJ_00438 1.E.43.1.1 100 1.5e-39 1 82 1.0000 1.0000 1 Channels/Pores 1.E Holins 1.E.43 The Putative Transglycosylase-associated Holin (T-A Hol) Family
NGINNMPJ_00463 8.A.99.1.1 93.6 1.1e-31 1 78 1.0000 1.0000 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.99 The BLP Braun's Lipoprotein (Lpp) Family
NGINNMPJ_00481 2.A.1.15.2 81 1.7e-165 2 394 0.9874 0.9777 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
NGINNMPJ_00517 3.A.1.107.3 72 1.4e-73 9 219 0.9635 1.0193 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00518 9.B.14.2.3 77.2 4.1e-109 1 241 0.9837 0.9837 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.14 The Putative Heme Handling Protein (HHP) Family
NGINNMPJ_00521 9.B.14.1.3 72.5 2.3e-276 1 650 1.0000 0.9938 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.14 The Putative Heme Handling Protein (HHP) Family
NGINNMPJ_00574 1.A.133.1.5 92.8 2e-92 1 181 0.9731 1.0000 1 Channels/Pores 1.A α-Type Channels 1.A.133 The Bacterial Csx28 Pore-forming (Csx28) Family
NGINNMPJ_00607 2.A.66.1.3 87.3 7.8e-223 1 457 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.66 The Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily
NGINNMPJ_00610 2.A.1.2.62 74.6 4e-159 3 386 0.9771 0.9578 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
NGINNMPJ_00614 2.A.1.2.65 87.7 1.4e-180 1 382 0.9845 0.9820 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
NGINNMPJ_00624 8.A.5.1.7 88.6 9.5e-153 1 298 1.0000 1.0000 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.5 The Voltage-gated K+ Channel β-subunit (Kvβ) Family
NGINNMPJ_00626 2.A.85.1.5 76.6 6.2e-301 1 672 0.9970 0.9897 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.85 The Aromatic Acid Exporter (ArAE) Family
NGINNMPJ_00628 8.A.48.1.1 76.9 2.3e-29 1 78 1.0000 1.0000 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.48 The Putative Auxiliary Aromatic Acid Exporter (AaeX) Family
NGINNMPJ_00638 2.A.17.1.2 86.4 1.9e-246 1 500 0.9980 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.17 The Proton-dependent Oligopeptide Transporter (POT/PTR) Family
NGINNMPJ_00644 3.D.6.1.4 82.6 0 1 753 1.0000 0.9986 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.6 The Ion (H+ or Na+)-translocating NADH:Ferredoxin Oxidoreductase (NFO or RNF) Family
NGINNMPJ_00669 2.A.16.1.1 77.5 1.7e-142 9 332 0.9701 0.9818 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.16 The Telurite-resistance/Dicarboxylate Transporter (TDT) Family
NGINNMPJ_00674 2.A.46.1.9 70.1 1.4e-140 1 385 0.9923 0.9847 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.46 The Benzoate:H+ Symporter (BenE) Family
NGINNMPJ_00684 3.A.1.11.9 86.4 3.1e-204 1 381 1.0000 1.1306 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00685 3.A.1.11.9 80.8 4.5e-151 1 333 0.9881 0.9881 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00686 3.A.1.11.9 88.6 4.7e-147 11 309 0.9676 0.8872 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00687 3.A.1.11.9 89.3 3.5e-130 1 262 0.9776 0.7774 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NGINNMPJ_00696 2.A.7.21.2 81.2 1.4e-59 1 149 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.7 The Drug/Metabolite Transporter (DMT) Superfamily
NGINNMPJ_00703 1.B.14.9.5 77.9 0 1 701 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.14 The Outer Membrane Receptor (OMR) Family
NGINNMPJ_00706 2.A.3.1.8 91.2 1.7e-252 1 480 0.9917 0.9658 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.3 The Amino Acid-Polyamine-Organocation (APC) Family
NGINNMPJ_00734 5.A.3.1.2 88 0 1 1246 1.0000 1.0000 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
NGINNMPJ_00735 2.A.1.8.10 80.1 1e-214 1 458 0.9957 0.9913 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
NGINNMPJ_00737 2.A.1.3.14 75.3 6.8e-188 1 490 0.9820 0.9899 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
NGINNMPJ_00746 2.A.7.17.1 75.3 1.6e-123 1 292 1.0000 0.9966 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.7 The Drug/Metabolite Transporter (DMT) Superfamily
NGINNMPJ_00748 5.A.3.2.1 90.7 0 1 803 1.0000 0.7911 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
NGINNMPJ_00754 2.A.1.2.14 72.3 1.2e-155 1 383 0.9974 0.9721 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
NGINNMPJ_00787 1.A.46.2.8 100 2.6e-174 1 305 1.0000 1.0000 1 Channels/Pores 1.A α-Type Channels 1.A.46 The Anion Channel-forming Bestrophin (Bestrophin) Family
NGINNMPJ_00798 9.B.20.1.1 70.9 7.9e-83 1 223 0.9867 0.9654 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.20 The Putative Mg2+ Transporter-C (MgtC) Family
NGINNMPJ_00801 2.A.76.1.10 80 1.3e-92 1 210 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.76 The Resistance to Homoserine/Threonine (RhtB) Family
NGINNMPJ_00876 4.A.7.1.4 99.3 2.5e-223 1 420 1.0000 1.0000 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.7 The PTS L-Ascorbate (L-Asc) Family
NGINNMPJ_00883 2.A.1.4.2 90.9 1e-241 1 463 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
NGINNMPJ_00990 2.A.1.2.15 81.4 6.3e-176 1 393 0.9850 0.9924 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
NGINNMPJ_00991 2.A.95.1.1 84.6 1.3e-98 1 221 0.9955 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.95 The 6 TMS Neutral Amino Acid Transporter (NAAT) Family
NGINNMPJ_00996 2.A.7.3.2 82.1 8.1e-128 1 290 0.9699 0.9699 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.7 The Drug/Metabolite Transporter (DMT) Superfamily
NGINNMPJ_00997 2.A.1.2.55 71.5 4.5e-158 1 389 0.9774 0.9848 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
HKGNBBPO_00023 1.A.13.5.1 99 5.8e-114 1 197 1.0000 0.7817 1 Channels/Pores 1.A α-Type Channels 1.A.13 The Epithelial Chloride Channel (E-ClC) Family
HKGNBBPO_00039 2.A.66.1.23 99.4 5.7e-272 1 484 1.0000 0.9778 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.66 The Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily
HKGNBBPO_00043 2.A.1.6.6 99.1 4.8e-246 1 438 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
HKGNBBPO_00047 1.B.14.8.7 99.1 0 1 673 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.14 The Outer Membrane Receptor (OMR) Family
HKGNBBPO_00054 3.A.1.21.1 99.8 0 1 600 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00055 3.A.1.21.1 99.7 0 1 600 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00056 2.A.1.57.3 97.2 6.2e-222 1 426 1.0000 0.9122 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
HKGNBBPO_00077 3.A.1.15.7 77.7 2e-123 1 283 0.9895 0.9279 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00079 3.A.1.15.7 73.3 1.3e-128 1 303 0.9967 0.9902 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00102 1.B.1.1.27 76.1 1.4e-169 1 381 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.1 The General Bacterial Porin (GBP) Family
HKGNBBPO_00107 2.A.7.3.22 80.2 2.3e-130 1 298 0.9835 0.9739 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.7 The Drug/Metabolite Transporter (DMT) Superfamily
HKGNBBPO_00115 3.A.1.3.10 89.8 3.7e-129 1 255 1.0000 1.0200 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00117 3.A.1.3.10 93.7 1.4e-111 1 222 1.0000 0.8880 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00118 3.A.1.3.10 91.2 9.2e-125 1 250 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00129 2.A.42.1.1 78.9 3.6e-165 1 380 1.0000 0.9429 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.42 The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family
HKGNBBPO_00137 3.A.1.2.2 91.7 1.7e-174 1 326 1.0000 0.9939 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00138 3.A.1.2.2 87.3 2.4e-257 1 504 1.0000 1.5366 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00139 3.A.1.2.2 92.3 1.8e-160 1 324 0.9939 0.9939 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00143 2.A.2.5.2 81.2 7.1e-236 1 512 0.9715 0.9865 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.2 The Glycoside-Pentoside-Hexuronide (GPH):Cation Symporter Family
HKGNBBPO_00224 3.A.1.15.5 92.7 5.6e-125 1 261 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00225 3.A.1.15.5 90.4 5.2e-128 1 250 1.0000 0.9579 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00226 3.A.1.15.5 76.4 1.1e-133 6 319 0.9843 1.1877 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00249 9.A.69.1.2 81.3 0 1 877 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.A Recognized transporters of unknown biochemical mechanism 9.A.69 The Intermembrane Phospholipid Translocase (IMPL-T) Family
HKGNBBPO_00253 9.B.174.1.2 89.9 0 1 682 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.174 The Two Tunnel Gated C-terminal Processing Protease (CTP) Family
HKGNBBPO_00254 9.B.1.1.6 91.5 1e-143 1 294 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.1 The Integral Membrane CAAX Protease (CAAX Protease) Family
HKGNBBPO_00255 2.A.1.3.17 79.8 2.2e-201 1 455 0.9978 0.9956 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
HKGNBBPO_00262 2.A.107.1.1 82.4 5.7e-87 1 188 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.107 The MntP Mn2+ exporter (MntP) Family
HKGNBBPO_00264 4.A.6.1.1 92.2 1.4e-148 1 283 1.0000 0.9895 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family
HKGNBBPO_00265 4.A.6.1.1 94 1.2e-130 1 266 1.0000 0.9301 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family
HKGNBBPO_00266 4.A.6.1.1 95.4 9.3e-170 1 323 1.0000 1.1294 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family
HKGNBBPO_00277 4.C.1.1.4 93 4.7e-310 12 571 0.9790 0.9982 4 Group Translocators 4.C Acyl CoA ligase-coupled transporters 4.C.1 The Fatty Acid Group Translocation (FAT) Family
HKGNBBPO_00286 5.A.2.1.1 79.5 8.6e-85 1 176 1.0000 1.0000 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.2 The Disulfide Bond Oxidoreductase B (DsbB) Family
HKGNBBPO_00287 2.A.34.1.1 85.4 5.4e-245 61 572 0.8889 0.9981 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.34 The NhaB Na+:H+ Antiporter (NhaB) Family
HKGNBBPO_00292 2.A.36.6.11 88.7 7.7e-292 1 577 1.0000 0.9983 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.36 The Monovalent Cation:Proton Antiporter-1 (CPA1) Family
HKGNBBPO_00306 2.A.42.2.2 91 3.3e-226 1 443 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.42 The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family
HKGNBBPO_00318 2.A.1.6.1 99.8 6.9e-229 13 431 0.9722 0.9437 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
HKGNBBPO_00355 2.A.53.3.11 89.3 9.6e-276 1 550 1.0000 0.9839 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.53 The Sulfate Permease (SulP) Family
HKGNBBPO_00358 1.B.46.1.1 82.1 1.6e-98 3 203 0.9901 0.9710 1 Channels/Pores 1.B β-Barrel Porins 1.B.46 The Outer Membrane LolAB Lipoprotein Insertion Apparatus (LolAB) Family
HKGNBBPO_00365 2.A.19.1.1 92.9 4.9e-183 1 366 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.19 The Ca2+:Cation Antiporter (CaCA) Family
HKGNBBPO_00379 2.A.1.8.1 86.5 6.7e-230 1 459 0.9935 0.9914 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
HKGNBBPO_00380 5.A.3.1.1 93.7 0 1 1247 1.0000 5.5422 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
HKGNBBPO_00381 5.A.3.1.1 93 1.2e-293 1 510 0.9980 2.2711 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
HKGNBBPO_00383 5.A.3.1.1 91.1 6.4e-117 1 224 0.9956 0.9956 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
HKGNBBPO_00396 2.A.95.1.7 88.8 3.3e-99 1 215 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.95 The 6 TMS Neutral Amino Acid Transporter (NAAT) Family
HKGNBBPO_00397 3.A.1.5.41 84 1.4e-279 1 544 1.0000 1.0150 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00408 2.C.1.1.1 75.7 7.5e-87 1 241 0.9837 0.9791 2 Electrochemical Potential-driven Transporters 2.C Ion-gradient-driven energizers 2.C.1 The TonB-ExbB-ExbD/TolA-TolQ-TolR Outer Membrane Receptor Energizers and Stabilizers (TonB/TolA) Family
HKGNBBPO_00412 1.B.75.1.3 84.5 1.2e-124 1 252 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.75 The DUF481 Putative Beta Barrel Porin (DUF481) Family
HKGNBBPO_00425 3.A.1.13.1 83.3 2.9e-150 1 324 0.9878 1.2180 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00435 2.A.86.2.1 78.9 5.3e-161 1 370 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.86 The Autoinducer-2 Exporter (AI-2E) Family (Formerly the PerM Family, TC #9.B.22)
HKGNBBPO_00438 1.E.43.1.1 100 1.5e-39 1 82 1.0000 1.0000 1 Channels/Pores 1.E Holins 1.E.43 The Putative Transglycosylase-associated Holin (T-A Hol) Family
HKGNBBPO_00463 8.A.99.1.1 93.6 1.1e-31 1 78 1.0000 1.0000 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.99 The BLP Braun's Lipoprotein (Lpp) Family
HKGNBBPO_00481 2.A.1.15.2 81 1.7e-165 2 394 0.9874 0.9777 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
HKGNBBPO_00517 3.A.1.107.3 72 1.4e-73 9 219 0.9635 1.0193 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00518 9.B.14.2.3 77.2 4.1e-109 1 241 0.9837 0.9837 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.14 The Putative Heme Handling Protein (HHP) Family
HKGNBBPO_00521 9.B.14.1.3 72.5 2.3e-276 1 650 1.0000 0.9938 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.14 The Putative Heme Handling Protein (HHP) Family
HKGNBBPO_00574 1.A.133.1.5 92.8 2e-92 1 181 0.9731 1.0000 1 Channels/Pores 1.A α-Type Channels 1.A.133 The Bacterial Csx28 Pore-forming (Csx28) Family
HKGNBBPO_00607 2.A.66.1.3 87.3 7.8e-223 1 457 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.66 The Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily
HKGNBBPO_00610 2.A.1.2.62 74.6 4e-159 3 386 0.9771 0.9578 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
HKGNBBPO_00614 2.A.1.2.65 87.7 1.4e-180 1 382 0.9845 0.9820 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
HKGNBBPO_00624 8.A.5.1.7 88.6 9.5e-153 1 298 1.0000 1.0000 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.5 The Voltage-gated K+ Channel β-subunit (Kvβ) Family
HKGNBBPO_00626 2.A.85.1.5 76.6 6.2e-301 1 672 0.9970 0.9897 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.85 The Aromatic Acid Exporter (ArAE) Family
HKGNBBPO_00628 8.A.48.1.1 76.9 2.3e-29 1 78 1.0000 1.0000 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.48 The Putative Auxiliary Aromatic Acid Exporter (AaeX) Family
HKGNBBPO_00638 2.A.17.1.2 86.4 1.9e-246 1 500 0.9980 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.17 The Proton-dependent Oligopeptide Transporter (POT/PTR) Family
HKGNBBPO_00644 3.D.6.1.4 82.6 0 1 753 1.0000 0.9986 3 Primary Active Transporters 3.D Oxidoreduction-driven transporters 3.D.6 The Ion (H+ or Na+)-translocating NADH:Ferredoxin Oxidoreductase (NFO or RNF) Family
HKGNBBPO_00669 2.A.16.1.1 77.5 1.7e-142 9 332 0.9701 0.9818 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.16 The Telurite-resistance/Dicarboxylate Transporter (TDT) Family
HKGNBBPO_00674 2.A.46.1.9 70.1 1.4e-140 1 385 0.9923 0.9847 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.46 The Benzoate:H+ Symporter (BenE) Family
HKGNBBPO_00684 3.A.1.11.9 86.4 3.1e-204 1 381 1.0000 1.1306 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00685 3.A.1.11.9 80.8 4.5e-151 1 333 0.9881 0.9881 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00686 3.A.1.11.9 88.6 4.7e-147 11 309 0.9676 0.8872 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00687 3.A.1.11.9 89.3 3.5e-130 1 262 0.9776 0.7774 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
HKGNBBPO_00696 2.A.7.21.2 81.2 1.4e-59 1 149 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.7 The Drug/Metabolite Transporter (DMT) Superfamily
HKGNBBPO_00703 1.B.14.9.5 77.9 0 1 701 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.14 The Outer Membrane Receptor (OMR) Family
HKGNBBPO_00706 2.A.3.1.8 91.2 1.7e-252 1 480 0.9917 0.9658 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.3 The Amino Acid-Polyamine-Organocation (APC) Family
HKGNBBPO_00734 5.A.3.1.2 88 0 1 1246 1.0000 1.0000 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
HKGNBBPO_00735 2.A.1.8.10 80.1 1e-214 1 458 0.9957 0.9913 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
HKGNBBPO_00737 2.A.1.3.14 75.3 6.8e-188 1 490 0.9820 0.9899 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
HKGNBBPO_00746 2.A.7.17.1 75.3 1.6e-123 1 292 1.0000 0.9966 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.7 The Drug/Metabolite Transporter (DMT) Superfamily
HKGNBBPO_00748 5.A.3.2.1 90.7 0 1 803 1.0000 0.7911 5 Transmembrane Electron Carriers 5.A Transmembrane 2-electron transfer carriers 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family
HKGNBBPO_00754 2.A.1.2.14 72.3 1.2e-155 1 383 0.9974 0.9721 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
HKGNBBPO_00787 1.A.46.2.8 100 2.6e-174 1 305 1.0000 1.0000 1 Channels/Pores 1.A α-Type Channels 1.A.46 The Anion Channel-forming Bestrophin (Bestrophin) Family
HKGNBBPO_00798 9.B.20.1.1 70.9 7.9e-83 1 223 0.9867 0.9654 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.20 The Putative Mg2+ Transporter-C (MgtC) Family
HKGNBBPO_00801 2.A.76.1.10 80 1.3e-92 1 210 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.76 The Resistance to Homoserine/Threonine (RhtB) Family
HKGNBBPO_00876 4.A.7.1.4 99.3 2.5e-223 1 420 1.0000 1.0000 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.7 The PTS L-Ascorbate (L-Asc) Family
HKGNBBPO_00883 2.A.1.4.2 90.9 1e-241 1 463 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
HKGNBBPO_00990 2.A.1.2.15 81.4 6.3e-176 1 393 0.9850 0.9924 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
HKGNBBPO_00991 2.A.95.1.1 84.6 1.3e-98 1 221 0.9955 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.95 The 6 TMS Neutral Amino Acid Transporter (NAAT) Family
HKGNBBPO_00996 2.A.7.3.2 82.1 8.1e-128 1 290 0.9699 0.9699 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.7 The Drug/Metabolite Transporter (DMT) Superfamily
HKGNBBPO_00997 2.A.1.2.55 71.5 4.5e-158 1 389 0.9774 0.9848 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)