Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C933
  Reference Plasmid   NZ_CP081910.1
  Reference Plasmid Size   8943
  Reference Plasmid GC Content   0.44
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0189066 AAIGBFFB_00006 6822 3 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -668G>A None
M0189067 AAIGBFFB_00006 5651 4 Gut 0.06 protein_coding synonymous_variant LOW 504G>A Gly168Gly
M0189068 AAIGBFFB_00006 5741 4 Gut 0.06 protein_coding missense_variant MODERATE 414A>C Glu138Asp
M0189069 AAIGBFFB_00006 5771 4 Gut 0.06 protein_coding synonymous_variant LOW 384T>C Tyr128Tyr
M0189070 AAIGBFFB_00006 5793 4 Gut 0.06 protein_coding missense_variant MODERATE 362A>G Lys121Arg
M0189071 AAIGBFFB_00006 5869 5 Gut 0.07 protein_coding missense_variant MODERATE 286T>C Cys96Arg
M0189072 AAIGBFFB_00007 6478 3 Gut 0.04 protein_coding synonymous_variant LOW 279G>A Arg93Arg
M0189073 AAIGBFFB_00007 6484 3 Gut 0.04 protein_coding synonymous_variant LOW 273T>C Ser91Ser
M0189074 AAIGBFFB_00007 6697 7 Gut 0.10 protein_coding synonymous_variant LOW 60T>C Asp20Asp
M0189075 AAIGBFFB_00006 6803 4 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -649G>T None
M0189076 AAIGBFFB_00006 7086 5 Gut 0.07 protein_coding upstream_gene_variant MODIFIER -932A>T None
M0189077 AAIGBFFB_00006 7087 5 Gut 0.07 protein_coding upstream_gene_variant MODIFIER -933G>T None
M0189078 AAIGBFFB_00006 7088 5 Gut 0.07 protein_coding upstream_gene_variant MODIFIER -934T>A None
M0189079 AAIGBFFB_00006 7102 4 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -948G>T None
M0189080 AAIGBFFB_00009 7629 3 Gut 0.04 protein_coding synonymous_variant LOW 129A>G Gln43Gln
M0189081 AAIGBFFB_00009 7689 3 Gut 0.04 protein_coding synonymous_variant LOW 189G>A Arg63Arg
M0189082 AAIGBFFB_00010 7898 4 Gut 0.06 protein_coding synonymous_variant LOW 90T>C His30His
M0189083 AAIGBFFB_00006 8235 3 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -2081G>A None
M0189084 AAIGBFFB_00006 8238 3 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -2084A>T None
M0189085 AAIGBFFB_00006 8584 3 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -2430T>C None
M0189086 AAIGBFFB_00006 8797 3 Gut 0.04 protein_coding upstream_gene_variant MODIFIER -2643A>G None
M0189087 AAIGBFFB_00006 5570 3 Gut 0.04 protein_coding synonymous_variant LOW 585C>A Arg195Arg
M0189088 AAIGBFFB_00006 5623 3 Gut 0.04 protein_coding missense_variant MODERATE 532G>A Gly178Ser
M0189089 AAIGBFFB_00006 5732 3 Gut 0.04 protein_coding synonymous_variant LOW 423C>T Ser141Ser
M0189090 AAIGBFFB_00006 5759 3 Gut 0.04 protein_coding synonymous_variant LOW 396T>C His132His
M0189091 AAIGBFFB_00006 5840 3 Gut 0.04 protein_coding synonymous_variant LOW 315G>A Arg105Arg
M0189092 AAIGBFFB_00006 5884 3 Gut 0.04 protein_coding missense_variant MODERATE 271A>G Arg91Gly
M0189093 AAIGBFFB_00006 6029 4 Gut 0.06 protein_coding synonymous_variant LOW 126G>A Pro42Pro
M0189094 AAIGBFFB_00008 7402 3 Gut 0.04 protein_coding synonymous_variant LOW 255A>G Thr85Thr
M0189095 AAIGBFFB_00005 3076 41 Gut 0.59 protein_coding missense_variant MODERATE 11A>C Asn4Thr
M0189096 AAIGBFFB_00005 3580 13 Gut 0.19 protein_coding missense_variant MODERATE 515C>T Ala172Val
M0189097 AAIGBFFB_00007 6625 3 Gut 0.04 protein_coding synonymous_variant LOW 132C>T Tyr44Tyr
M0189098 AAIGBFFB_00001 490 6 Gut 0.09 protein_coding missense_variant MODERATE 152G>A Gly51Glu
M0189099 AAIGBFFB_00006 5684 6 Gut 0.09 protein_coding synonymous_variant LOW 471C>T Thr157Thr
M0189100 AAIGBFFB_00006 5797 6 Gut 0.09 protein_coding synonymous_variant LOW 358T>C Leu120Leu
M0189101 AAIGBFFB_00006 6874 5 Gut 0.07 protein_coding upstream_gene_variant MODIFIER -720C>T None
M0189102 AAIGBFFB_00003 2865 12 Gut 0.17 protein_coding upstream_gene_variant MODIFIER -1245C>T None
M0189103 AAIGBFFB_00006 6982 10 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -828G>T None
M0189104 AAIGBFFB_00001 379 3 Gut 0.04 protein_coding missense_variant MODERATE 41A>G Asn14Ser
M0189105 AAIGBFFB_00001 392 4 Gut 0.06 protein_coding synonymous_variant LOW 54A>G Arg18Arg
M0189106 AAIGBFFB_00001 407 4 Gut 0.06 protein_coding missense_variant MODERATE 69A>G Ile23Met
M0189107 AAIGBFFB_00010 7922 6 Gut 0.09 protein_coding synonymous_variant LOW 114A>G Pro38Pro
M0189108 AAIGBFFB_00010 7967 3 Gut 0.04 protein_coding synonymous_variant LOW 159T>G Thr53Thr
M0189109 AAIGBFFB_00006 6026 3 Gut 0.04 protein_coding synonymous_variant LOW 129C>T Phe43Phe
M0189110 AAIGBFFB_00007 6556 4 Gut 0.06 protein_coding synonymous_variant LOW 201G>A Gln67Gln
M0189111 AAIGBFFB_00006 6813 4 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -659C>T None
M0189112 AAIGBFFB_00010 7919 5 Gut 0.07 protein_coding synonymous_variant LOW 111G>A Thr37Thr
M0189113 AAIGBFFB_00006 6927 7 Gut 0.10 protein_coding upstream_gene_variant MODIFIER -773C>T None
M0189114 AAIGBFFB_00010 7877 9 Gut 0.13 protein_coding synonymous_variant LOW 69C>T Leu23Leu
M0189115 AAIGBFFB_00001 489 3 Gut 0.04 protein_coding missense_variant MODERATE 151G>A Gly51Arg
M0189116 AAIGBFFB_00002 708 3 Gut 0.04 protein_coding missense_variant MODERATE 76A>C Lys26Gln
M0189117 AAIGBFFB_00006 8274 4 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2120G>A None
M0189118 AAIGBFFB_00004 2421 3 Gut 0.04 protein_coding missense_variant MODERATE 673C>T Leu225Phe
M0189119 AAIGBFFB_00004 2229 3 Gut 0.04 protein_coding missense_variant MODERATE 481G>A Val161Ile
M0189120 AAIGBFFB_00010 7854 3 Gut 0.04 protein_coding missense_variant MODERATE 46C>T Arg16Cys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term