Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C934
  Reference Plasmid   NZ_CP081911.1
  Reference Plasmid Size   35580
  Reference Plasmid GC Content   0.32
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0189121 MHNOLLKB_00019 14401 5 Gut 0.19 protein_coding synonymous_variant LOW 345G>A Leu115Leu
M0189122 MHNOLLKB_00024 17825 12 Gut 0.44 protein_coding missense_variant MODERATE 800T>C Leu267Ser
M0189123 MHNOLLKB_00025 18577 5 Gut 0.19 protein_coding missense_variant MODERATE 28A>G Thr10Ala
M0189124 MHNOLLKB_00026 18860 5 Gut 0.19 protein_coding synonymous_variant LOW 216T>C Asp72Asp
M0189125 MHNOLLKB_00026 19209 6 Gut 0.22 protein_coding missense_variant MODERATE 565A>C Lys189Gln
M0189126 MHNOLLKB_00026 19314 6 Gut 0.22 protein_coding missense_variant MODERATE 670A>T Thr224Ser
M0189127 MHNOLLKB_00027 19382 3 Gut 0.11 protein_coding missense_variant MODERATE 17A>G Lys6Arg
M0189128 MHNOLLKB_00027 19383 3 Gut 0.11 protein_coding missense_variant MODERATE 18A>T Lys6Asn
M0189129 MHNOLLKB_00027 19392 3 Gut 0.11 protein_coding synonymous_variant LOW 27T>C Ala9Ala
M0189130 MHNOLLKB_00027 19393 3 Gut 0.11 protein_coding synonymous_variant LOW 28T>C Leu10Leu
M0189131 MHNOLLKB_00027 19431 3 Gut 0.11 protein_coding synonymous_variant LOW 66A>C Ala22Ala
M0189132 MHNOLLKB_00027 19441 3 Gut 0.11 protein_coding missense_variant MODERATE 76A>G Ile26Val
M0189133 MHNOLLKB_00027 20028 6 Gut 0.22 protein_coding synonymous_variant LOW 663G>A Glu221Glu
M0189134 MHNOLLKB_00027 20095 6 Gut 0.22 protein_coding missense_variant MODERATE 730A>G Thr244Ala
M0189135 MHNOLLKB_00031 23296 4 Gut 0.15 protein_coding synonymous_variant LOW 69C>T Gly23Gly
M0189136 MHNOLLKB_00031 23599 6 Gut 0.22 protein_coding synonymous_variant LOW 372A>G Ser124Ser
M0189137 MHNOLLKB_00036 25459 6 Gut 0.22 protein_coding upstream_gene_variant MODIFIER -137A>G None
M0189138 MHNOLLKB_00037 26099 10 Gut 0.37 protein_coding synonymous_variant LOW 276C>T Phe92Phe
M0189139 MHNOLLKB_00037 26570 11 Gut 0.41 protein_coding synonymous_variant LOW 747A>G Lys249Lys
M0189140 MHNOLLKB_00037 27452 3 Gut 0.11 protein_coding synonymous_variant LOW 1629C>T Gly543Gly
M0189141 MHNOLLKB_00041 30143 3 Gut 0.11 protein_coding missense_variant MODERATE 1058T>C Ile353Thr
M0189142 MHNOLLKB_00041 30679 3 Gut 0.11 protein_coding synonymous_variant LOW 522C>T Asp174Asp
M0189143 MHNOLLKB_00041 30904 3 Gut 0.11 protein_coding missense_variant MODERATE 297G>T Glu99Asp
M0189144 MHNOLLKB_00039 31427 4 Gut 0.15 protein_coding upstream_gene_variant MODIFIER -2544A>G None
M0189145 MHNOLLKB_00039 31480 3 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -2597T>C None
M0189146 MHNOLLKB_00039 32657 3 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -3774C>G None
M0189147 MHNOLLKB_00039 32806 3 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -3923T>C None
M0189148 MHNOLLKB_00001 582 3 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -193C>T None
M0189149 MHNOLLKB_00031 28375 3 Gut 0.11 protein_coding downstream_gene_variant MODIFIER *4311A>G None
M0189150 MHNOLLKB_00021 15870 12 Gut 0.44 protein_coding synonymous_variant LOW 39A>G Ser13Ser
M0189151 MHNOLLKB_00027 20742 4 Gut 0.15 protein_coding synonymous_variant LOW 1377G>A Lys459Lys
M0189152 MHNOLLKB_00032 24355 4 Gut 0.15 protein_coding missense_variant MODERATE 295G>A Asp99Asn
M0189153 MHNOLLKB_00034 24793 4 Gut 0.15 protein_coding synonymous_variant LOW 99G>A Lys33Lys
M0189154 MHNOLLKB_00037 26457 3 Gut 0.11 protein_coding missense_variant MODERATE 634G>A Val212Ile
M0189155 MHNOLLKB_00037 26900 5 Gut 0.19 protein_coding synonymous_variant LOW 1077C>A Ser359Ser
M0189156 MHNOLLKB_00031 28305 4 Gut 0.15 protein_coding downstream_gene_variant MODIFIER *4241G>A None
M0189157 MHNOLLKB_00031 28339 4 Gut 0.15 protein_coding downstream_gene_variant MODIFIER *4275T>A None
M0189158 MHNOLLKB_00031 28359 3 Gut 0.11 protein_coding downstream_gene_variant MODIFIER *4295G>A None
M0189159 MHNOLLKB_00020 15404 8 Gut 0.30 protein_coding upstream_gene_variant MODIFIER -87C>T None
M0189160 MHNOLLKB_00020 15405 5 Gut 0.19 protein_coding upstream_gene_variant MODIFIER -86C>A None
M0189161 MHNOLLKB_00021 15990 3 Gut 0.11 protein_coding synonymous_variant LOW 159C>T Asp53Asp
M0189162 MHNOLLKB_00025 18313 4 Gut 0.15 protein_coding missense_variant MODERATE 292A>G Ile98Val
M0189163 MHNOLLKB_00027 19651 4 Gut 0.15 protein_coding missense_variant MODERATE 286G>A Glu96Lys
M0189164 MHNOLLKB_00027 19897 5 Gut 0.19 protein_coding missense_variant MODERATE 532A>G Ile178Val
M0189165 MHNOLLKB_00032 24287 3 Gut 0.11 protein_coding missense_variant MODERATE 227A>G Asn76Ser
M0189166 MHNOLLKB_00033 24623 3 Gut 0.11 protein_coding synonymous_variant LOW 198T>A Thr66Thr
M0189167 MHNOLLKB_00022 16547 3 Gut 0.11 protein_coding synonymous_variant LOW 270C>T Arg90Arg
M0189168 MHNOLLKB_00027 19659 4 Gut 0.15 protein_coding synonymous_variant LOW 294C>T His98His
M0189169 MHNOLLKB_00031 23695 3 Gut 0.11 protein_coding synonymous_variant LOW 468C>T Ala156Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
MHNOLLKB_00029 9.B.154.1.1 95.2 3.1e-84 1 167 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.154 The Putative Holin-2 (PH-2) Family