Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C937
  Reference Plasmid   NZ_CP081918.1
  Reference Plasmid Size   190391
  Reference Plasmid GC Content   0.42
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0189199 PCABBKBE_00178 169023 4 Gut 0.29 protein_coding upstream_gene_variant MODIFIER -2818C>T None
M0189200 PCABBKBE_00180 169108 7 Gut 0.50 protein_coding synonymous_variant LOW 9A>G Lys3Lys
M0189201 PCABBKBE_00180 169109 7 Gut 0.50 protein_coding missense_variant MODERATE 10G>A Val4Ile
M0189202 PCABBKBE_00180 169144 5 Gut 0.36 protein_coding synonymous_variant LOW 45A>G Gly15Gly
M0189203 PCABBKBE_00180 169156 5 Gut 0.36 protein_coding synonymous_variant LOW 57T>G Ser19Ser
M0189204 PCABBKBE_00180 169246 5 Gut 0.36 protein_coding synonymous_variant LOW 147A>G Glu49Glu
M0189205 PCABBKBE_00180 169282 5 Gut 0.36 protein_coding synonymous_variant LOW 183C>T Gly61Gly
M0189206 PCABBKBE_00180 169372 5 Gut 0.36 protein_coding synonymous_variant LOW 273G>A Leu91Leu
M0189207 PCABBKBE_00180 169395 5 Gut 0.36 protein_coding missense_variant MODERATE 296G>T Cys99Phe
M0189208 PCABBKBE_00180 169401 5 Gut 0.36 protein_coding missense_variant MODERATE 302A>G Asn101Ser
M0189209 PCABBKBE_00180 169414 5 Gut 0.36 protein_coding synonymous_variant LOW 315A>G Lys105Lys
M0189210 PCABBKBE_00180 169429 5 Gut 0.36 protein_coding missense_variant MODERATE 330C>A Asn110Lys
M0189211 PCABBKBE_00180 169469 5 Gut 0.36 protein_coding synonymous_variant LOW 370T>C Leu124Leu
M0189212 PCABBKBE_00180 169472 5 Gut 0.36 protein_coding missense_variant MODERATE 373A>G Ile125Val
M0189213 PCABBKBE_00180 169477 5 Gut 0.36 protein_coding missense_variant MODERATE 378A>T Lys126Asn
M0189214 PCABBKBE_00180 169606 5 Gut 0.36 protein_coding synonymous_variant LOW 507C>T Gly169Gly
M0189215 PCABBKBE_00180 169666 5 Gut 0.36 protein_coding synonymous_variant LOW 567A>G Val189Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
PCABBKBE_00002 QUT23463.1|GT2 100 1.32e-210 1 284 1 1
PCABBKBE_00004 QUR43251.1|GT2 100 3.35e-285 1 404 1 1
PCABBKBE_00072 QRM97425.1|GT51 100 1.49e-168 1 247 1 1
PCABBKBE_00187 QUR43234.1|GT2 100 1.23e-223 1 300 1 1
PCABBKBE_00188 QUR43235.1|GT2 100 4.1e-270 1 386 1 1
PCABBKBE_00189 QUR43236.1|GT4 100 2.1e-268 1 369 1 1
PCABBKBE_00198 UBF10870.1|GT0 100 2.06e-280 1 370 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term