Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C939
  Reference Plasmid   NZ_CP081921.1
  Reference Plasmid Size   35580
  Reference Plasmid GC Content   0.32
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0189219 IALOJFMI_00015 11660 6 Gut 0.22 protein_coding synonymous_variant LOW 360G>A Ser120Ser
M0189220 IALOJFMI_00016 12739 4 Gut 0.15 protein_coding synonymous_variant LOW 298C>T Leu100Leu
M0189221 IALOJFMI_00017 13301 4 Gut 0.15 protein_coding synonymous_variant LOW 120G>A Glu40Glu
M0189222 IALOJFMI_00018 13711 3 Gut 0.11 protein_coding missense_variant MODERATE 169C>A Leu57Ile
M0189223 IALOJFMI_00018 13714 3 Gut 0.11 protein_coding missense_variant MODERATE 172G>A Val58Ile
M0189224 IALOJFMI_00018 13723 3 Gut 0.11 protein_coding missense_variant MODERATE 181G>A Val61Ile
M0189225 IALOJFMI_00018 13728 3 Gut 0.11 protein_coding synonymous_variant LOW 186A>G Gly62Gly
M0189226 IALOJFMI_00018 13812 3 Gut 0.11 protein_coding synonymous_variant LOW 270T>C Phe90Phe
M0189227 IALOJFMI_00018 13815 3 Gut 0.11 protein_coding synonymous_variant LOW 273G>C Leu91Leu
M0189228 IALOJFMI_00019 13864 3 Gut 0.11 protein_coding synonymous_variant LOW 6G>A Ser2Ser
M0189229 IALOJFMI_00019 13871 3 Gut 0.11 protein_coding missense_variant MODERATE 13T>C Tyr5His
M0189230 IALOJFMI_00019 13875 3 Gut 0.11 protein_coding missense_variant MODERATE 17C>T Pro6Leu
M0189231 IALOJFMI_00019 13876 3 Gut 0.11 protein_coding synonymous_variant LOW 18A>T Pro6Pro
M0189232 IALOJFMI_00019 13942 3 Gut 0.11 protein_coding synonymous_variant LOW 84A>T Ile28Ile
M0189233 IALOJFMI_00019 14023 3 Gut 0.11 protein_coding synonymous_variant LOW 165T>C Gly55Gly
M0189234 IALOJFMI_00019 14029 3 Gut 0.11 protein_coding synonymous_variant LOW 171T>G Thr57Thr
M0189235 IALOJFMI_00019 14068 3 Gut 0.11 protein_coding synonymous_variant LOW 210G>A Ser70Ser
M0189236 IALOJFMI_00019 14069 3 Gut 0.11 protein_coding missense_variant MODERATE 211C>A Gln71Lys
M0189237 IALOJFMI_00019 14086 3 Gut 0.11 protein_coding synonymous_variant LOW 228G>A Gly76Gly
M0189238 IALOJFMI_00019 14094 3 Gut 0.11 protein_coding missense_variant MODERATE 236G>A Arg79Lys
M0189239 IALOJFMI_00019 14138 3 Gut 0.11 protein_coding missense_variant MODERATE 280A>G Ile94Val
M0189240 IALOJFMI_00020 14232 3 Gut 0.11 protein_coding synonymous_variant LOW 69C>T Phe23Phe
M0189241 IALOJFMI_00020 14604 4 Gut 0.15 protein_coding synonymous_variant LOW 441C>T Asn147Asn
M0189242 IALOJFMI_00020 14797 4 Gut 0.15 protein_coding missense_variant MODERATE 634G>A Val212Ile
M0189243 IALOJFMI_00020 14835 4 Gut 0.15 protein_coding synonymous_variant LOW 672G>A Arg224Arg
M0189244 IALOJFMI_00020 14875 4 Gut 0.15 protein_coding missense_variant MODERATE 712G>A Gly238Ser
M0189245 IALOJFMI_00020 15162 4 Gut 0.15 protein_coding synonymous_variant LOW 999T>C Cys333Cys
M0189246 IALOJFMI_00020 15270 4 Gut 0.15 protein_coding synonymous_variant LOW 1107C>T Phe369Phe
M0189247 IALOJFMI_00013 10613 3 Gut 0.11 protein_coding missense_variant MODERATE 197T>C Val66Ala
M0189248 IALOJFMI_00014 10992 4 Gut 0.15 protein_coding stop_lost&splice_region_variant HIGH 206A>T Ter69Leuext*?
M0189249 IALOJFMI_00007 12104 4 Gut 0.15 protein_coding upstream_gene_variant MODIFIER -3970T>A None
M0189250 IALOJFMI_00020 15072 3 Gut 0.11 protein_coding synonymous_variant LOW 909A>C Ile303Ile
M0189251 IALOJFMI_00021 17407 3 Gut 0.11 protein_coding synonymous_variant LOW 393A>T Val131Val
M0189252 IALOJFMI_00022 17746 3 Gut 0.11 protein_coding missense_variant MODERATE 56C>T Thr19Ile
M0189253 IALOJFMI_00022 17789 3 Gut 0.11 protein_coding synonymous_variant LOW 99G>A Val33Val
M0189254 IALOJFMI_00024 19970 3 Gut 0.11 protein_coding synonymous_variant LOW 576A>C Leu192Leu
M0189255 IALOJFMI_00025 20079 4 Gut 0.15 protein_coding missense_variant MODERATE 71C>T Ala24Val
M0189256 IALOJFMI_00026 20859 3 Gut 0.11 protein_coding missense_variant MODERATE 416C>T Thr139Ile
M0189257 IALOJFMI_00026 20869 3 Gut 0.11 protein_coding synonymous_variant LOW 426G>A Arg142Arg
M0189258 IALOJFMI_00026 20944 3 Gut 0.11 protein_coding synonymous_variant LOW 501A>G Leu167Leu
M0189259 IALOJFMI_00026 21264 4 Gut 0.15 protein_coding missense_variant MODERATE 821G>A Arg274Lys
M0189260 IALOJFMI_00026 21286 3 Gut 0.11 protein_coding synonymous_variant LOW 843T>C Ser281Ser
M0189261 IALOJFMI_00026 21445 4 Gut 0.15 protein_coding synonymous_variant LOW 1002C>T Ala334Ala
M0189262 IALOJFMI_00028 22844 3 Gut 0.11 protein_coding synonymous_variant LOW 438C>A Val146Val
M0189263 IALOJFMI_00028 22907 3 Gut 0.11 protein_coding missense_variant MODERATE 501T>A Asn167Lys
M0189264 IALOJFMI_00029 23047 3 Gut 0.11 protein_coding synonymous_variant LOW 135A>G Ser45Ser
M0189265 IALOJFMI_00029 23061 3 Gut 0.11 protein_coding missense_variant MODERATE 149A>G Asn50Ser
M0189266 IALOJFMI_00029 23113 3 Gut 0.11 protein_coding synonymous_variant LOW 201T>A Pro67Pro
M0189267 IALOJFMI_00029 23114 3 Gut 0.11 protein_coding missense_variant MODERATE 202G>A Asp68Asn
M0189268 IALOJFMI_00029 23176 3 Gut 0.11 protein_coding synonymous_variant LOW 264T>C Asp88Asp
M0189269 IALOJFMI_00029 23266 3 Gut 0.11 protein_coding synonymous_variant LOW 354A>G Lys118Lys
M0189270 IALOJFMI_00029 23308 3 Gut 0.11 protein_coding synonymous_variant LOW 396C>T Tyr132Tyr
M0189271 IALOJFMI_00029 23311 3 Gut 0.11 protein_coding synonymous_variant LOW 399A>G Ala133Ala
M0189272 IALOJFMI_00030 23611 3 Gut 0.11 protein_coding missense_variant MODERATE 37G>A Val13Ile
M0189273 IALOJFMI_00030 23893 3 Gut 0.11 protein_coding synonymous_variant LOW 319C>T Leu107Leu
M0189274 IALOJFMI_00030 24120 3 Gut 0.11 protein_coding synonymous_variant LOW 546A>G Gly182Gly
M0189275 IALOJFMI_00030 24165 3 Gut 0.11 protein_coding synonymous_variant LOW 591A>G Gly197Gly
M0189276 IALOJFMI_00031 24280 3 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -729G>A None
M0189277 IALOJFMI_00009 8751 3 Gut 0.11 protein_coding synonymous_variant LOW 231A>G Glu77Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
IALOJFMI_00040 9.B.154.1.1 95.2 3.1e-84 1 167 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.154 The Putative Holin-2 (PH-2) Family