Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C940
  Reference Plasmid   NZ_CP082078.1
  Reference Plasmid Size   142433
  Reference Plasmid GC Content   0.49
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0189278 CELFONND_00061 61784 16 Gut 0.64 protein_coding upstream_gene_variant MODIFIER -4881A>G None
M0189279 CELFONND_00061 61806 16 Gut 0.64 protein_coding upstream_gene_variant MODIFIER -4903A>T None
M0189280 CELFONND_00061 61820 16 Gut 0.64 protein_coding upstream_gene_variant MODIFIER -4917C>T None
M0189281 CELFONND_00062 61982 16 Gut 0.64 protein_coding upstream_gene_variant MODIFIER -3747C>A None
M0189282 CELFONND_00067 62174 16 Gut 0.64 protein_coding synonymous_variant LOW 57T>C Ser19Ser
M0189283 CELFONND_00061 61799 14 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -4896T>C None
M0189284 CELFONND_00061 61850 8 Gut 0.32 protein_coding upstream_gene_variant MODIFIER -4947G>T None
M0189285 CELFONND_00061 61873 8 Gut 0.32 protein_coding upstream_gene_variant MODIFIER -4970G>A None
M0189286 CELFONND_00061 61887 14 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -4984G>T None
M0189287 CELFONND_00067 62459 14 Gut 0.56 protein_coding synonymous_variant LOW 342A>G Gly114Gly
M0189288 CELFONND_00067 62582 14 Gut 0.56 protein_coding synonymous_variant LOW 465G>C Val155Val
M0189289 CELFONND_00067 62597 14 Gut 0.56 protein_coding synonymous_variant LOW 480T>C Arg160Arg
M0189290 CELFONND_00067 62684 13 Gut 0.52 protein_coding synonymous_variant LOW 567G>A Pro189Pro
M0189291 CELFONND_00067 62696 14 Gut 0.56 protein_coding synonymous_variant LOW 579C>T Gly193Gly
M0189292 CELFONND_00067 62732 14 Gut 0.56 protein_coding missense_variant MODERATE 615G>T Glu205Asp
M0189293 CELFONND_00067 62744 14 Gut 0.56 protein_coding synonymous_variant LOW 627G>T Leu209Leu
M0189294 CELFONND_00067 62885 14 Gut 0.56 protein_coding synonymous_variant LOW 768G>A Pro256Pro
M0189295 CELFONND_00067 63008 13 Gut 0.52 protein_coding synonymous_variant LOW 891C>A Ile297Ile
M0189296 CELFONND_00067 63080 14 Gut 0.56 protein_coding synonymous_variant LOW 963T>C Pro321Pro
M0189297 CELFONND_00067 63188 13 Gut 0.52 protein_coding synonymous_variant LOW 1071A>T Pro357Pro
M0189298 CELFONND_00067 63215 14 Gut 0.56 protein_coding synonymous_variant LOW 1098G>A Thr366Thr
M0189299 CELFONND_00064 63258 13 Gut 0.52 protein_coding upstream_gene_variant MODIFIER -3262T>A None
M0189300 CELFONND_00064 63266 14 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -3270T>G None
M0189301 CELFONND_00064 63309 14 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -3313G>A None
M0189302 CELFONND_00068 63699 9 Gut 0.36 protein_coding synonymous_variant LOW 327G>A Gln109Gln
M0189303 CELFONND_00068 63901 8 Gut 0.32 protein_coding synonymous_variant LOW 529C>T Leu177Leu
M0189304 CELFONND_00068 63951 14 Gut 0.56 protein_coding synonymous_variant LOW 579G>A Gly193Gly
M0189305 CELFONND_00068 63952 14 Gut 0.56 protein_coding missense_variant MODERATE 580C>A Leu194Met
M0189306 CELFONND_00068 63960 14 Gut 0.56 protein_coding synonymous_variant LOW 588A>G Ser196Ser
M0189307 CELFONND_00068 64131 12 Gut 0.48 protein_coding synonymous_variant LOW 759C>T Thr253Thr
M0189308 CELFONND_00068 64473 11 Gut 0.44 protein_coding synonymous_variant LOW 1101C>T Ala367Ala
M0189309 CELFONND_00068 64476 12 Gut 0.48 protein_coding synonymous_variant LOW 1104T>G Gly368Gly
M0189310 CELFONND_00068 64630 12 Gut 0.48 protein_coding missense_variant MODERATE 1258A>C Ser420Arg
M0189311 CELFONND_00068 65107 12 Gut 0.48 protein_coding missense_variant MODERATE 1735G>A Val579Met
M0189312 CELFONND_00068 65310 7 Gut 0.28 protein_coding synonymous_variant LOW 1938G>A Ala646Ala
M0189313 CELFONND_00068 65355 6 Gut 0.24 protein_coding synonymous_variant LOW 1983G>A Ala661Ala
M0189314 CELFONND_00068 65370 12 Gut 0.48 protein_coding synonymous_variant LOW 1998A>G Val666Val
M0189315 CELFONND_00068 65410 12 Gut 0.48 protein_coding missense_variant MODERATE 2038A>G Thr680Ala
M0189316 CELFONND_00068 65426 12 Gut 0.48 protein_coding missense_variant MODERATE 2054T>C Ile685Thr
M0189317 CELFONND_00068 65460 4 Gut 0.16 protein_coding synonymous_variant LOW 2088G>A Leu696Leu
M0189318 CELFONND_00068 65547 6 Gut 0.24 protein_coding synonymous_variant LOW 2175C>T Arg725Arg
M0189319 CELFONND_00068 65586 6 Gut 0.24 protein_coding synonymous_variant LOW 2214T>C His738His
M0189320 CELFONND_00068 65610 7 Gut 0.28 protein_coding synonymous_variant LOW 2238T>G Leu746Leu
M0189321 CELFONND_00068 65731 7 Gut 0.28 protein_coding missense_variant MODERATE 2359T>A Phe787Ile
M0189322 CELFONND_00068 65820 6 Gut 0.24 protein_coding synonymous_variant LOW 2448G>A Gln816Gln
M0189323 CELFONND_00068 65871 12 Gut 0.48 protein_coding synonymous_variant LOW 2499T>C Ser833Ser
M0189324 CELFONND_00068 66557 10 Gut 0.40 protein_coding missense_variant MODERATE 3185T>G Leu1062Arg
M0189325 CELFONND_00070 68483 12 Gut 0.48 protein_coding missense_variant MODERATE 34T>C Tyr12His
M0189326 CELFONND_00070 68612 7 Gut 0.28 protein_coding missense_variant MODERATE 163G>A Ala55Thr
M0189327 CELFONND_00070 68890 13 Gut 0.52 protein_coding synonymous_variant LOW 441G>A Ser147Ser
M0189328 CELFONND_00070 69304 13 Gut 0.52 protein_coding synonymous_variant LOW 855A>G Leu285Leu
M0189329 CELFONND_00071 69853 12 Gut 0.48 protein_coding missense_variant MODERATE 1776T>G Asp592Glu
M0189330 CELFONND_00071 69865 12 Gut 0.48 protein_coding synonymous_variant LOW 1764G>A Pro588Pro
M0189331 CELFONND_00071 69937 7 Gut 0.28 protein_coding synonymous_variant LOW 1692C>T Gly564Gly
M0189332 CELFONND_00068 65004 5 Gut 0.20 protein_coding synonymous_variant LOW 1632G>A Thr544Thr
M0189333 CELFONND_00068 65187 5 Gut 0.20 protein_coding synonymous_variant LOW 1815C>T Asp605Asp
M0189334 CELFONND_00068 66030 5 Gut 0.20 protein_coding synonymous_variant LOW 2658C>T Ala886Ala
M0189335 CELFONND_00068 66228 5 Gut 0.20 protein_coding synonymous_variant LOW 2856G>C Gly952Gly
M0189336 CELFONND_00068 66336 5 Gut 0.20 protein_coding synonymous_variant LOW 2964T>A Pro988Pro
M0189337 CELFONND_00068 66651 6 Gut 0.24 protein_coding synonymous_variant LOW 3279G>A Pro1093Pro
M0189338 CELFONND_00068 66942 5 Gut 0.20 protein_coding synonymous_variant LOW 3570A>G Ala1190Ala
M0189339 CELFONND_00069 67537 5 Gut 0.20 protein_coding synonymous_variant LOW 402G>A Lys134Lys
M0189340 CELFONND_00069 67579 5 Gut 0.20 protein_coding synonymous_variant LOW 444A>G Gly148Gly
M0189341 CELFONND_00069 67823 6 Gut 0.24 protein_coding missense_variant MODERATE 688A>G Arg230Gly
M0189342 CELFONND_00069 67906 6 Gut 0.24 protein_coding synonymous_variant LOW 771G>A Lys257Lys
M0189343 CELFONND_00069 67924 6 Gut 0.24 protein_coding synonymous_variant LOW 789A>C Ala263Ala
M0189344 CELFONND_00069 67945 6 Gut 0.24 protein_coding synonymous_variant LOW 810C>T Ile270Ile
M0189345 CELFONND_00069 67965 6 Gut 0.24 protein_coding missense_variant MODERATE 830G>A Arg277His
M0189346 CELFONND_00069 68188 6 Gut 0.24 protein_coding synonymous_variant LOW 1053G>A Val351Val
M0189347 CELFONND_00071 70872 11 Gut 0.44 protein_coding missense_variant MODERATE 757A>G Ile253Val
M0189348 CELFONND_00071 71335 10 Gut 0.40 protein_coding synonymous_variant LOW 294A>T Arg98Arg
M0189349 CELFONND_00071 71395 10 Gut 0.40 protein_coding synonymous_variant LOW 234C>T Val78Val
M0189350 CELFONND_00071 71568 10 Gut 0.40 protein_coding missense_variant MODERATE 61A>G Ile21Val
M0189351 CELFONND_00071 71587 10 Gut 0.40 protein_coding synonymous_variant LOW 42G>A Leu14Leu
M0189352 CELFONND_00071 71715 10 Gut 0.40 protein_coding upstream_gene_variant MODIFIER -87T>A None
M0189353 CELFONND_00071 71720 5 Gut 0.20 protein_coding upstream_gene_variant MODIFIER -92T>C None
M0189354 CELFONND_00071 71723 10 Gut 0.40 protein_coding upstream_gene_variant MODIFIER -95A>T None
M0189355 CELFONND_00071 71747 10 Gut 0.40 protein_coding upstream_gene_variant MODIFIER -119T>A None
M0189356 CELFONND_00071 71776 10 Gut 0.40 protein_coding upstream_gene_variant MODIFIER -148A>T None
M0189357 CELFONND_00071 71779 9 Gut 0.36 protein_coding upstream_gene_variant MODIFIER -151A>G None
M0189358 CELFONND_00069 67720 5 Gut 0.20 protein_coding synonymous_variant LOW 585T>C Asp195Asp
M0189359 CELFONND_00069 67721 5 Gut 0.20 protein_coding missense_variant MODERATE 586G>A Val196Ile
M0189360 CELFONND_00069 68245 5 Gut 0.20 protein_coding synonymous_variant LOW 1110G>A Gln370Gln
M0189361 CELFONND_00068 69433 6 Gut 0.24 protein_coding downstream_gene_variant MODIFIER *2401A>G None
M0189362 CELFONND_00071 69478 6 Gut 0.24 protein_coding synonymous_variant LOW 2151C>T Tyr717Tyr
M0189363 CELFONND_00039 36148 4 Gut 0.16 protein_coding synonymous_variant LOW 192A>G Glu64Glu
M0189364 CELFONND_00069 67927 4 Gut 0.16 protein_coding synonymous_variant LOW 792A>G Gly264Gly
M0189365 CELFONND_00069 68230 4 Gut 0.16 protein_coding synonymous_variant LOW 1095G>T Val365Val
M0189366 CELFONND_00070 69155 5 Gut 0.20 protein_coding missense_variant MODERATE 706G>A Ala236Thr
M0189367 CELFONND_00071 69714 5 Gut 0.20 protein_coding missense_variant MODERATE 1915G>T Val639Phe
M0189368 CELFONND_00071 70829 5 Gut 0.20 protein_coding missense_variant MODERATE 800C>T Ala267Val
M0189369 CELFONND_00035 32725 3 Gut 0.12 protein_coding missense_variant MODERATE 155T>C Leu52Pro
M0189370 CELFONND_00035 32734 3 Gut 0.12 protein_coding missense_variant MODERATE 164T>C Val55Ala
M0189371 CELFONND_00035 32785 3 Gut 0.12 protein_coding missense_variant MODERATE 215C>A Ala72Glu
M0189372 CELFONND_00035 32858 3 Gut 0.12 protein_coding synonymous_variant LOW 288G>T Leu96Leu
M0189373 CELFONND_00035 32861 3 Gut 0.12 protein_coding synonymous_variant LOW 291C>G Ala97Ala
M0189374 CELFONND_00035 32864 3 Gut 0.12 protein_coding synonymous_variant LOW 294T>C Thr98Thr
M0189375 CELFONND_00035 32870 3 Gut 0.12 protein_coding synonymous_variant LOW 300G>A Lys100Lys
M0189376 CELFONND_00035 32873 3 Gut 0.12 protein_coding synonymous_variant LOW 303G>A Gln101Gln
M0189377 CELFONND_00035 32879 3 Gut 0.12 protein_coding synonymous_variant LOW 309A>C Thr103Thr
M0189378 CELFONND_00035 32916 3 Gut 0.12 protein_coding missense_variant MODERATE 346G>A Gly116Ser
M0189379 CELFONND_00035 32918 3 Gut 0.12 protein_coding synonymous_variant LOW 348T>C Gly116Gly
M0189380 CELFONND_00035 32951 3 Gut 0.12 protein_coding synonymous_variant LOW 381C>T Asp127Asp
M0189381 CELFONND_00035 32952 3 Gut 0.12 protein_coding missense_variant MODERATE 382T>A Ser128Thr
M0189382 CELFONND_00035 33002 3 Gut 0.12 protein_coding synonymous_variant LOW 432C>T Pro144Pro
M0189383 CELFONND_00035 33010 3 Gut 0.12 protein_coding missense_variant MODERATE 440G>T Arg147Leu
M0189384 CELFONND_00035 33013 3 Gut 0.12 protein_coding missense_variant MODERATE 443G>A Arg148His
M0189385 CELFONND_00035 33070 3 Gut 0.12 protein_coding missense_variant MODERATE 500C>G Thr167Arg
M0189386 CELFONND_00035 33071 3 Gut 0.12 protein_coding synonymous_variant LOW 501G>T Thr167Thr
M0189387 CELFONND_00035 33079 3 Gut 0.12 protein_coding missense_variant MODERATE 509C>T Thr170Ile
M0189388 CELFONND_00035 33109 3 Gut 0.12 protein_coding missense_variant MODERATE 539C>A Ala180Asp
M0189389 CELFONND_00035 33116 3 Gut 0.12 protein_coding synonymous_variant LOW 546C>T Asp182Asp
M0189390 CELFONND_00035 33143 3 Gut 0.12 protein_coding synonymous_variant LOW 573A>G Thr191Thr
M0189391 CELFONND_00035 33175 3 Gut 0.12 protein_coding missense_variant MODERATE 605A>T His202Leu
M0189392 CELFONND_00035 33308 3 Gut 0.12 protein_coding missense_variant MODERATE 738G>A Met246Ile
M0189393 CELFONND_00030 33424 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4138T>G None
M0189394 CELFONND_00030 33429 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4143G>T None
M0189395 CELFONND_00030 33447 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4161G>A None
M0189396 CELFONND_00030 33452 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4166T>C None
M0189397 CELFONND_00030 33460 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4174G>A None
M0189398 CELFONND_00030 33461 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4175G>A None
M0189399 CELFONND_00030 33473 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4187G>A None
M0189400 CELFONND_00030 33479 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4193C>T None
M0189401 CELFONND_00030 33486 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4200G>A None
M0189402 CELFONND_00030 33490 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4204C>T None
M0189403 CELFONND_00030 33502 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4216A>C None
M0189404 CELFONND_00036 33670 3 Gut 0.12 protein_coding synonymous_variant LOW 141T>G Pro47Pro
M0189405 CELFONND_00036 33727 3 Gut 0.12 protein_coding synonymous_variant LOW 198T>A Ile66Ile
M0189406 CELFONND_00036 33817 3 Gut 0.12 protein_coding synonymous_variant LOW 288T>A Ala96Ala
M0189407 CELFONND_00036 33844 3 Gut 0.12 protein_coding synonymous_variant LOW 315C>T Asp105Asp
M0189408 CELFONND_00036 34042 3 Gut 0.12 protein_coding synonymous_variant LOW 513A>T Ala171Ala
M0189409 CELFONND_00036 34045 3 Gut 0.12 protein_coding synonymous_variant LOW 516A>G Glu172Glu
M0189410 CELFONND_00030 34207 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4921A>G None
M0189411 CELFONND_00030 34212 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4926A>C None
M0189412 CELFONND_00030 34233 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4947C>T None
M0189413 CELFONND_00037 34345 3 Gut 0.12 protein_coding missense_variant MODERATE 85A>G Ile29Val
M0189414 CELFONND_00037 34358 3 Gut 0.12 protein_coding missense_variant MODERATE 98C>T Ala33Val
M0189415 CELFONND_00037 34484 3 Gut 0.12 protein_coding missense_variant MODERATE 224C>T Thr75Ile
M0189416 CELFONND_00037 34551 3 Gut 0.12 protein_coding synonymous_variant LOW 291T>C Asp97Asp
M0189417 CELFONND_00031 34580 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -3744T>C None
M0189418 CELFONND_00031 34581 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -3745A>G None
M0189419 CELFONND_00031 34591 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -3755T>C None
M0189420 CELFONND_00031 34631 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -3795T>C None
M0189421 CELFONND_00031 34917 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4081C>T None
M0189422 CELFONND_00031 34940 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4104G>A None
M0189423 CELFONND_00031 34941 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4105T>C None
M0189424 CELFONND_00031 34953 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4117A>G None
M0189425 CELFONND_00031 34969 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -4133G>A None
M0189426 CELFONND_00038 35181 3 Gut 0.12 protein_coding synonymous_variant LOW 198A>T Val66Val
M0189427 CELFONND_00038 35253 3 Gut 0.12 protein_coding synonymous_variant LOW 270C>T Gly90Gly
M0189428 CELFONND_00038 35280 3 Gut 0.12 protein_coding synonymous_variant LOW 297C>T Ile99Ile
M0189429 CELFONND_00038 35335 3 Gut 0.12 protein_coding missense_variant MODERATE 352A>C Asn118His
M0189430 CELFONND_00038 35345 3 Gut 0.12 protein_coding missense_variant MODERATE 362G>A Arg121Lys
M0189431 CELFONND_00038 35383 3 Gut 0.12 protein_coding missense_variant MODERATE 400G>A Gly134Arg
M0189432 CELFONND_00038 35385 3 Gut 0.12 protein_coding synonymous_variant LOW 402G>T Gly134Gly
M0189433 CELFONND_00038 35406 3 Gut 0.12 protein_coding synonymous_variant LOW 423T>C Arg141Arg
M0189434 CELFONND_00038 35619 3 Gut 0.12 protein_coding synonymous_variant LOW 636A>G Val212Val
M0189435 CELFONND_00039 36200 3 Gut 0.12 protein_coding missense_variant MODERATE 244G>A Val82Ile
M0189436 CELFONND_00039 36235 3 Gut 0.12 protein_coding synonymous_variant LOW 279G>A Leu93Leu
M0189437 CELFONND_00039 36236 3 Gut 0.12 protein_coding missense_variant MODERATE 280A>C Ile94Leu
M0189438 CELFONND_00039 36287 3 Gut 0.12 protein_coding missense_variant MODERATE 331A>G Thr111Ala
M0189439 CELFONND_00039 36311 3 Gut 0.12 protein_coding missense_variant MODERATE 355T>G Ser119Ala
M0189440 CELFONND_00040 36390 3 Gut 0.12 protein_coding synonymous_variant LOW 375G>A Leu125Leu
M0189441 CELFONND_00040 36455 3 Gut 0.12 protein_coding missense_variant MODERATE 310G>A Glu104Lys
M0189442 CELFONND_00040 36502 3 Gut 0.12 protein_coding missense_variant MODERATE 263A>T Gln88Leu
M0189443 CELFONND_00040 36537 3 Gut 0.12 protein_coding synonymous_variant LOW 228T>C Ser76Ser
M0189444 CELFONND_00040 36547 3 Gut 0.12 protein_coding missense_variant MODERATE 218G>A Arg73His
M0189445 CELFONND_00040 36548 3 Gut 0.12 protein_coding missense_variant MODERATE 217C>T Arg73Cys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
CELFONND_00023 VFG000940 Aerobactin 94.8 0 1 574 1.0 1 Nutritional/Metabolic factor aerobactin siderophore biosynthesis protein IucD experiment
CELFONND_00024 VFG000939 Aerobactin 96.2 1.7e-190 1 315 1.0 1 Nutritional/Metabolic factor aerobactin siderophore biosynthesis protein IucB experiment
CELFONND_00025 VFG000938 Aerobactin 97.6 0 1 580 1.0 1 Nutritional/Metabolic factor aerobactin siderophore biosynthesis protein IucC experiment
CELFONND_00026 VFG000937 Aerobactin 97.9 1.3e-252 1 425 1.0 0.9551 Nutritional/Metabolic factor L-lysine 6-monooxygenase IucD experiment
CELFONND_00027 VFG048621 Aerobactin 99.6 0 1 732 1.0 0.9986 Nutritional/Metabolic factor ferric aerobactin receptor IutA experiment
CELFONND_00067 VFG012513 Salmochelin siderophore 99.7 2.8e-219 1 371 1.0 1 Nutritional/Metabolic factor glucosyltransferase IroB experiment
CELFONND_00068 VFG012509 Salmochelin siderophore 99.4 0 1 1219 1.0 1 Nutritional/Metabolic factor ATP binding cassette transporter experiment
CELFONND_00069 VFG012505 Salmochelin siderophore 99.8 1e-243 1 409 1.0 1 Nutritional/Metabolic factor esterase experiment
CELFONND_00070 VFG012501 Salmochelin siderophore 99.4 2.2e-188 1 318 1.0 1 Nutritional/Metabolic factor esterase experiment
CELFONND_00071 VFG000935 Salmochelin siderophore 99.3 0 1 725 1.0 1 Nutritional/Metabolic factor salmochelin receptor IroN experiment
CELFONND_00091 VFG000904 Vat 79.3 0 1 1377 1.0 1.0007 Effector delivery system vacuolating autotransporter toxin experiment
CELFONND_00004 VFG043979 Colicin B 99.8 4.7e-290 1 511 1.0 1 Exotoxin colicin B prediction
CELFONND_00009 VFG012575 Iron/manganese transport 99.7 2.2e-173 1 304 1.0 1 Nutritional/Metabolic factor iron/manganese ABC transporter substrate-binding protein SitA prediction
CELFONND_00010 VFG034214 Iron/manganese transport 100 5.5e-152 1 275 1.0 1 Nutritional/Metabolic factor iron/manganese ABC transporter ATP-binding protein SitB prediction
CELFONND_00011 VFG012585 Iron/manganese transport 100 1.4e-153 1 285 1.0 1 Nutritional/Metabolic factor iron/manganese ABC transporter permease subunit SitC prediction
CELFONND_00012 VFG012590 Iron/manganese transport 100 3.8e-148 1 285 1.0 1 Nutritional/Metabolic factor iron/manganese ABC transporter permease subunit SitD prediction
CELFONND_00023 VFG012526 Aerobactin 99.8 0 1 574 1.0 1 Nutritional/Metabolic factor aerobactin siderophore biosynthesis protein IucD prediction
CELFONND_00024 VFG033993 Aerobactin 99.7 3.2e-196 1 315 1.0 1 Nutritional/Metabolic factor aerobactin siderophore biosynthesis protein IucB prediction
CELFONND_00025 VFG012522 Aerobactin 100 0 1 580 1.0 1 Nutritional/Metabolic factor aerobactin siderophore biosynthesis protein IucC prediction
CELFONND_00026 VFG033958 Aerobactin 100 3.7e-256 1 425 1.0 1 Nutritional/Metabolic factor L-lysine 6-monooxygenase IucD prediction
CELFONND_00027 VFG033944 Aerobactin 99.9 0 1 732 1.0 0.9986 Nutritional/Metabolic factor ferric aerobactin receptor precusor IutA prediction
CELFONND_00067 VFG012514 Salmochelin siderophore 100 9.2e-219 1 371 1.0 1 Nutritional/Metabolic factor glucosyltransferase IroB prediction
CELFONND_00068 VFG033929 Salmochelin siderophore 99.6 0 1 1219 1.0 1 Nutritional/Metabolic factor ATP binding cassette transporter prediction
CELFONND_00069 VFG012505 Salmochelin siderophore 99.8 7.7e-243 1 409 1.0 1 Nutritional/Metabolic factor esterase prediction
CELFONND_00070 VFG012503 Salmochelin siderophore 99.4 1.6e-187 1 318 1.0 1 Nutritional/Metabolic factor esterase prediction
CELFONND_00071 VFG033911 Salmochelin siderophore 100 0 1 725 1.0 1 Nutritional/Metabolic factor salmochelin receptor IroN prediction
CELFONND_00091 VFG042364 Hbp (hemoglobin-binding protease) 99.3 0 1 1377 1.0 1 Effector delivery system haemoglobin protease prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
CELFONND_00009 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 75.8 1.5e-133 8 304 0.9770 0.9738 experiment
CELFONND_00010 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 77.7 3.7e-115 2 266 0.9636 0.9707 experiment
CELFONND_00011 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 87 9e-133 1 277 0.9719 0.9685 experiment
CELFONND_00009 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 76.4 5.2e-132 8 304 0.9770 0.9738 prediction
CELFONND_00010 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 81.1 2.3e-118 2 266 0.9636 0.9707 prediction
CELFONND_00011 Manganese (Mn), Iron (Fe), Hydrogen Peroxide (H2O2) [class: Peroxides] 87.8 3.4e-133 1 279 0.9789 0.9789 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
CELFONND_00009 PHI:10082 STM14_RS15345 75.8 2.5e-132 8 304 0.9770 0.9705 eudicots infection manganese/iron ABC transporter ATP-binding protein unaffected pathogenicity
CELFONND_00010 PHI:10083 STM14_RS15350 77.7 6.1e-114 2 266 0.9636 0.9707 eudicots infection iron ABC transporter permease unaffected pathogenicity
CELFONND_00011 PHI:10084 STM14_RS15355 87 1.5e-131 1 277 0.9719 0.9685 eudicots infection iron ABC transporter permease unaffected pathogenicity
CELFONND_00023 PHI:124067 iucA (PAGR_g3927) 78.4 6.3e-270 1 573 0.9983 0.9598 monocots None aerobactin siderophores unaffected pathogenicity
CELFONND_00024 PHI:124068 iucB (PAGR_g3926) 80 1.2e-158 1 315 1.0000 1.0000 monocots None aerobactin siderophores unaffected pathogenicity
CELFONND_00025 PHI:124069 iucC (PAGR_g3925) 83.9 9.1e-301 1 577 0.9948 0.9983 monocots None aerobactin siderophores unaffected pathogenicity
CELFONND_00026 PHI:3610 iucD 100 1.3e-256 1 425 1.0000 1.0000 birds colibacillosis aerobactin reduced virulence
CELFONND_00027 PHI:6563 iucA 99.6 0 1 732 1.0000 0.9986 rodents pneumonia aerobactin reduced virulence
CELFONND_00046 PHI:6531 HlyF 100 2.6e-216 1 369 1.0000 1.0000 birds colibacillosis hemolysin reduced virulence
CELFONND_00067 PHI:6564 iroB 90.3 3.4e-200 1 371 1.0000 1.0000 rodents pneumonia salmochelin unaffected pathogenicity
CELFONND_00068 PHI:9461 iroC 79.8 0 1 1205 0.9885 0.9926 primates salmonellosis putative ABC transporter protein reduced virulence
CELFONND_00069 PHI:4860 IroD 99.8 1.4e-242 1 409 1.0000 1.0000 birds respiratory disease (poultry); systemic disease (poultry) catecholate siderophore esterases reduced virulence
CELFONND_00070 PHI:4861 IroE 99.1 2.2e-187 1 318 1.0000 1.0000 birds respiratory disease (poultry); systemic disease (poultry) catecholate siderophore esterases unaffected pathogenicity
CELFONND_00071 PHI:9464 iroN 82.3 0 1 725 1.0000 0.9972 primates salmonellosis TonB-dependent outer membrane siderophore receptor protein reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
CELFONND_00067 CAD66179.1|GT1 100 1.38e-274 1 371 1 1
CELFONND_00140 QBQ68813.1|GH23 99.4 2.36e-122 1 169 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
CELFONND_00004 1.C.1.3.2 99.8 3.7e-290 1 511 1.0000 1.0000 1 Channels/Pores 1.C Pore-Forming Toxins (Proteins and Peptides) 1.C.1 The Channel-forming Colicin (Colicin) Family
CELFONND_00007 8.B.24.3.1 99.1 3.2e-64 1 117 1.0000 0.8298 8 Accessory Factors Involved in Transport 8.B Ribosomally synthesized protein/peptide toxins/agonists that target channels and carriers 8.B.24 The Colicin Immunity Protein (ColIP) Functional Family
CELFONND_00009 3.A.1.15.7 75.8 5.5e-132 8 304 0.9770 0.9705 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
CELFONND_00010 3.A.1.15.7 77.7 1.4e-113 2 266 0.9636 0.8689 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
CELFONND_00011 3.A.1.15.7 87 3.4e-131 1 277 0.9719 0.9082 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
CELFONND_00047 9.B.50.1.1 73.2 3.9e-144 1 317 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.50 The Outer Membrane Beta-barrel Endoprotease, Omptin (Omptin) Family
CELFONND_00068 3.A.1.106.7 79.6 0 1 1205 0.9885 0.9926 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
CELFONND_00071 1.B.14.1.3 82.2 0 1 725 1.0000 0.9972 1 Channels/Pores 1.B β-Barrel Porins 1.B.14 The Outer Membrane Receptor (OMR) Family
CELFONND_00078 3.A.1.112.12 99.7 0 1 698 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
CELFONND_00079 1.C.31.1.1 100 4.6e-54 1 103 1.0000 1.0000 1 Channels/Pores 1.C Pore-Forming Toxins (Proteins and Peptides) 1.C.31 The Channel-forming Colicin V (Colicin V) Family
CELFONND_00083 2.A.123.2.16 98.9 5e-41 1 89 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.123 The Sweet; PQ-loop; Saliva; MtN3 (Sweet) Family
CELFONND_00091 1.B.12.4.2 99.3 0 1 1377 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.12 The Autotransporter-1 (AT-1) Family
CELFONND_00097 1.E.53.1.11 95.9 2.1e-20 1 49 1.0000 0.7206 1 Channels/Pores 1.E Holins 1.E.53 The Toxic Hok/Gef Protein (Hok/Gef) Family