Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C960
  Reference Plasmid   NZ_CP084441.1
  Reference Plasmid Size   31852
  Reference Plasmid GC Content   0.29
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0105013 LBIHLFLH_00034 27597 14 Skin 0.58 protein_coding missense_variant MODERATE 259T>C Phe87Leu
M0105014 LBIHLFLH_00034 27602 14 Skin 0.58 protein_coding synonymous_variant LOW 264A>G Val88Val
M0105015 LBIHLFLH_00034 27611 14 Skin 0.58 protein_coding missense_variant MODERATE 273G>A Met91Ile
M0105016 LBIHLFLH_00034 27625 14 Skin 0.58 protein_coding missense_variant MODERATE 287A>G Asn96Ser
M0105017 LBIHLFLH_00034 27670 14 Skin 0.58 protein_coding missense_variant MODERATE 332C>T Ala111Val
M0105018 LBIHLFLH_00034 27710 14 Skin 0.58 protein_coding synonymous_variant LOW 372C>T His124His
M0105019 LBIHLFLH_00034 27739 15 Skin 0.63 protein_coding missense_variant MODERATE 401G>A Arg134Lys
M0105020 LBIHLFLH_00035 28104 17 Skin 0.71 protein_coding synonymous_variant LOW 132G>C Val44Val
M0105021 LBIHLFLH_00035 28128 17 Skin 0.71 protein_coding synonymous_variant LOW 156T>C Tyr52Tyr
M0105022 LBIHLFLH_00035 28143 17 Skin 0.71 protein_coding missense_variant MODERATE 171A>C Glu57Asp
M0105023 LBIHLFLH_00035 28270 17 Skin 0.71 protein_coding missense_variant MODERATE 298G>A Asp100Asn
M0105024 LBIHLFLH_00033 27278 5 Skin 0.21 protein_coding synonymous_variant LOW 1455T>A Gly485Gly
M0105025 LBIHLFLH_00033 27286 5 Skin 0.21 protein_coding missense_variant MODERATE 1463C>T Ala488Val
M0105026 LBIHLFLH_00028 27335 9 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4415T>G None
M0105027 LBIHLFLH_00028 27336 9 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4416A>T None
M0105028 LBIHLFLH_00028 27338 9 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4418T>C None
M0105029 LBIHLFLH_00034 27345 9 Skin 0.38 protein_coding missense_variant MODERATE 7A>T Asn3Tyr
M0105030 LBIHLFLH_00034 27348 9 Skin 0.38 protein_coding missense_variant MODERATE 10A>G Ile4Val
M0105031 LBIHLFLH_00034 27353 9 Skin 0.38 protein_coding synonymous_variant LOW 15T>C Tyr5Tyr
M0105032 LBIHLFLH_00034 27359 9 Skin 0.38 protein_coding synonymous_variant LOW 21A>T Ile7Ile
M0105033 LBIHLFLH_00034 27372 9 Skin 0.38 protein_coding synonymous_variant LOW 34C>A Arg12Arg
M0105034 LBIHLFLH_00034 27380 9 Skin 0.38 protein_coding missense_variant MODERATE 42A>C Lys14Asn
M0105035 LBIHLFLH_00034 27401 9 Skin 0.38 protein_coding synonymous_variant LOW 63A>C Arg21Arg
M0105036 LBIHLFLH_00034 27422 9 Skin 0.38 protein_coding synonymous_variant LOW 84G>A Glu28Glu
M0105037 LBIHLFLH_00034 27500 11 Skin 0.46 protein_coding synonymous_variant LOW 162G>A Glu54Glu
M0105038 LBIHLFLH_00034 27515 11 Skin 0.46 protein_coding synonymous_variant LOW 177T>C Asn59Asn
M0105039 LBIHLFLH_00034 27545 6 Skin 0.25 protein_coding missense_variant MODERATE 207A>T Gln69His
M0105040 LBIHLFLH_00034 27559 6 Skin 0.25 protein_coding missense_variant MODERATE 221G>C Gly74Ala
M0105041 LBIHLFLH_00034 27563 6 Skin 0.25 protein_coding synonymous_variant LOW 225T>C Gly75Gly
M0105042 LBIHLFLH_00034 27564 6 Skin 0.25 protein_coding missense_variant MODERATE 226A>G Ile76Val
M0105043 LBIHLFLH_00034 27569 6 Skin 0.25 protein_coding synonymous_variant LOW 231T>C Gly77Gly
M0105044 LBIHLFLH_00034 27574 12 Skin 0.50 protein_coding missense_variant MODERATE 236T>C Ile79Thr
M0105045 LBIHLFLH_00034 27918 7 Skin 0.29 protein_coding missense_variant MODERATE 580T>A Ser194Thr
M0105046 LBIHLFLH_00034 27552 6 Skin 0.25 protein_coding missense_variant MODERATE 214A>C Met72Leu
M0105047 LBIHLFLH_00034 27554 6 Skin 0.25 protein_coding missense_variant MODERATE 216G>A Met72Ile
M0105048 LBIHLFLH_00034 27557 6 Skin 0.25 protein_coding synonymous_variant LOW 219T>A Ala73Ala
M0105049 LBIHLFLH_00034 27585 6 Skin 0.25 protein_coding synonymous_variant LOW 247C>T Leu83Leu
M0105050 LBIHLFLH_00021 14729 4 Skin 0.17 protein_coding missense_variant MODERATE 813C>G Phe271Leu
M0105051 LBIHLFLH_00021 15318 3 Skin 0.13 protein_coding missense_variant MODERATE 224C>T Thr75Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
LBIHLFLH_00029 ARO:3000621 99.3 1.56e-195 1 281 1.0000 1.0000 penicillin beta-lactam BlaZ beta-lactamase antibiotic inactivation






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term