Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C974
  Reference Plasmid   NZ_CP087337.1
  Reference Plasmid Size   102971
  Reference Plasmid GC Content   0.40
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0105252 PEEBKFOF_00094 78704 4 Skin 0.18 protein_coding splice_region_variant&stop_retained_variant LOW 1076A>G Ter359Ter
M0105253 PEEBKFOF_00111 98886 3 Skin 0.14 protein_coding missense_variant MODERATE 260C>G Pro87Arg
M0105254 PEEBKFOF_00111 98981 3 Skin 0.14 protein_coding synonymous_variant LOW 165C>T Gly55Gly
M0105255 PEEBKFOF_00111 99075 3 Skin 0.14 protein_coding missense_variant MODERATE 71A>G Tyr24Cys
M0105256 PEEBKFOF_00111 99126 3 Skin 0.14 protein_coding missense_variant MODERATE 20A>G His7Arg
M0105257 PEEBKFOF_00107 99216 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -4971A>G None
M0105258 PEEBKFOF_00107 99221 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -4976T>G None
M0105259 PEEBKFOF_00108 99328 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -2713A>C None
M0105260 PEEBKFOF_00108 95637 3 Skin 0.14 protein_coding missense_variant MODERATE 979A>G Thr327Ala
M0105261 PEEBKFOF_00108 95685 3 Skin 0.14 protein_coding missense_variant MODERATE 931A>G Ile311Val
M0105262 PEEBKFOF_00108 95785 3 Skin 0.14 protein_coding synonymous_variant LOW 831T>A Pro277Pro
M0105263 PEEBKFOF_00108 95938 3 Skin 0.14 protein_coding synonymous_variant LOW 678G>T Leu226Leu
M0105264 PEEBKFOF_00108 96076 3 Skin 0.14 protein_coding synonymous_variant LOW 540T>C His180His
M0105265 PEEBKFOF_00108 96210 3 Skin 0.14 protein_coding synonymous_variant LOW 406C>T Leu136Leu
M0105266 PEEBKFOF_00108 96298 3 Skin 0.14 protein_coding synonymous_variant LOW 318C>T Gly106Gly
M0105267 PEEBKFOF_00108 96322 3 Skin 0.14 protein_coding synonymous_variant LOW 294A>G Arg98Arg
M0105268 PEEBKFOF_00108 96324 3 Skin 0.14 protein_coding synonymous_variant LOW 292A>C Arg98Arg
M0105269 PEEBKFOF_00108 96325 3 Skin 0.14 protein_coding synonymous_variant LOW 291C>T Tyr97Tyr
M0105270 PEEBKFOF_00108 96340 3 Skin 0.14 protein_coding synonymous_variant LOW 276A>G Glu92Glu
M0105271 PEEBKFOF_00108 96346 3 Skin 0.14 protein_coding missense_variant MODERATE 270T>A Asn90Lys
M0105272 PEEBKFOF_00106 96616 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -3817G>T None
M0105273 PEEBKFOF_00106 96715 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -3916C>T None
M0105274 PEEBKFOF_00106 96750 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -3951C>T None
M0105275 PEEBKFOF_00106 96756 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -3957C>G None
M0105276 PEEBKFOF_00106 96805 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -4006T>C None
M0105277 PEEBKFOF_00106 96817 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -4018A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
PEEBKFOF_00105 1.B.25.1.36 75.4 5.2e-189 14 415 0.9687 0.9687 1 Channels/Pores 1.B β-Barrel Porins 1.B.25 The Outer Membrane Porin (Opr) Family