Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C978
  Reference Plasmid   NZ_CP089048.1
  Reference Plasmid Size   90792
  Reference Plasmid GC Content   0.38
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0105278 EKMMGANA_00027 23479 3 Skin 0.13 protein_coding synonymous_variant LOW 402T>A Pro134Pro
M0105279 EKMMGANA_00027 23663 3 Skin 0.13 protein_coding missense_variant MODERATE 586C>G His196Asp
M0105280 EKMMGANA_00064 55843 3 Skin 0.13 protein_coding synonymous_variant LOW 105C>A Val35Val
M0105281 EKMMGANA_00064 56017 3 Skin 0.13 protein_coding synonymous_variant LOW 279A>T Ile93Ile
M0105282 EKMMGANA_00064 56137 3 Skin 0.13 protein_coding synonymous_variant LOW 399T>C Phe133Phe
M0105283 EKMMGANA_00064 56143 3 Skin 0.13 protein_coding synonymous_variant LOW 405G>C Thr135Thr
M0105284 EKMMGANA_00064 56224 3 Skin 0.13 protein_coding synonymous_variant LOW 486C>T Gly162Gly
M0105285 EKMMGANA_00064 56233 3 Skin 0.13 protein_coding synonymous_variant LOW 495T>G Val165Val
M0105286 EKMMGANA_00064 56585 3 Skin 0.13 protein_coding missense_variant MODERATE 847G>A Val283Ile
M0105287 EKMMGANA_00065 56766 3 Skin 0.13 protein_coding missense_variant MODERATE 43T>A Cys15Ser
M0105288 EKMMGANA_00062 59579 3 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -4605A>T None
M0105289 EKMMGANA_00068 59718 3 Skin 0.13 protein_coding missense_variant MODERATE 80T>C Met27Thr
M0105290 EKMMGANA_00068 59839 3 Skin 0.13 protein_coding synonymous_variant LOW 201T>G Gly67Gly
M0105291 EKMMGANA_00057 52511 3 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -3059A>T None
M0105292 EKMMGANA_00057 52563 3 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -3111G>T None
M0105293 EKMMGANA_00057 52585 3 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -3133A>G None
M0105294 EKMMGANA_00057 52635 4 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -3183T>A None
M0105295 EKMMGANA_00057 52765 3 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -3313G>A None
M0105296 EKMMGANA_00061 52827 4 Skin 0.17 protein_coding synonymous_variant LOW 807C>T Phe269Phe
M0105297 EKMMGANA_00061 53073 5 Skin 0.22 protein_coding synonymous_variant LOW 561T>C Tyr187Tyr
M0105298 EKMMGANA_00061 53205 3 Skin 0.13 protein_coding synonymous_variant LOW 429T>G Gly143Gly
M0105299 EKMMGANA_00061 53214 3 Skin 0.13 protein_coding synonymous_variant LOW 420T>C Ser140Ser
M0105300 EKMMGANA_00061 53241 4 Skin 0.17 protein_coding synonymous_variant LOW 393A>G Leu131Leu
M0105301 EKMMGANA_00061 53298 5 Skin 0.22 protein_coding synonymous_variant LOW 336G>A Ser112Ser
M0105302 EKMMGANA_00061 53399 5 Skin 0.22 protein_coding missense_variant MODERATE 235A>C Thr79Pro
M0105303 EKMMGANA_00061 53481 6 Skin 0.26 protein_coding synonymous_variant LOW 153G>A Gly51Gly
M0105304 EKMMGANA_00061 53569 4 Skin 0.17 protein_coding missense_variant MODERATE 65C>T Thr22Ile
M0105305 EKMMGANA_00057 53813 5 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -4361T>G None
M0105306 EKMMGANA_00057 53820 3 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -4368A>T None
M0105307 EKMMGANA_00062 54156 4 Skin 0.17 protein_coding synonymous_variant LOW 819T>C Ala273Ala
M0105308 EKMMGANA_00062 54438 3 Skin 0.13 protein_coding synonymous_variant LOW 537T>C His179His
M0105309 EKMMGANA_00062 54465 3 Skin 0.13 protein_coding synonymous_variant LOW 510G>T Gly170Gly
M0105310 EKMMGANA_00062 54708 3 Skin 0.13 protein_coding synonymous_variant LOW 267T>C Thr89Thr
M0105311 EKMMGANA_00062 54723 3 Skin 0.13 protein_coding synonymous_variant LOW 252T>A Val84Val
M0105312 EKMMGANA_00062 54834 4 Skin 0.17 protein_coding synonymous_variant LOW 141G>A Leu47Leu
M0105313 EKMMGANA_00062 54846 5 Skin 0.22 protein_coding synonymous_variant LOW 129T>C Asp43Asp
M0105314 EKMMGANA_00062 54879 3 Skin 0.13 protein_coding synonymous_variant LOW 96T>C Ile32Ile
M0105315 EKMMGANA_00062 54900 4 Skin 0.17 protein_coding synonymous_variant LOW 75A>G Pro25Pro
M0105316 EKMMGANA_00063 55116 4 Skin 0.17 protein_coding synonymous_variant LOW 156G>A Leu52Leu
M0105317 EKMMGANA_00059 55630 4 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -4068C>T None
M0105318 EKMMGANA_00059 55635 4 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -4073G>A None
M0105319 EKMMGANA_00059 55692 3 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -4130A>G None
M0105320 EKMMGANA_00059 55707 3 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -4145A>G None
M0105321 EKMMGANA_00059 55717 3 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -4155A>G None
M0105322 EKMMGANA_00061 52902 3 Skin 0.13 protein_coding synonymous_variant LOW 732T>G Leu244Leu
M0105323 EKMMGANA_00061 52947 3 Skin 0.13 protein_coding synonymous_variant LOW 687G>A Arg229Arg
M0105324 EKMMGANA_00061 53175 4 Skin 0.17 protein_coding synonymous_variant LOW 459A>C Val153Val
M0105325 EKMMGANA_00062 54377 3 Skin 0.13 protein_coding synonymous_variant LOW 598C>T Leu200Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
EKMMGANA_00016 ALV72695.1|GT2 99.5 1.12e-158 1 214 1 1
EKMMGANA_00018 UYF77491.1|GT20 100 0 1 478 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term