Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C979
  Reference Plasmid   NZ_CP089308.1
  Reference Plasmid Size   66795
  Reference Plasmid GC Content   0.44
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0191520 HFJIGMLC_00043 33964 3 Gut 0.75 protein_coding synonymous_variant LOW 957A>G Ala319Ala
M0191521 HFJIGMLC_00043 34368 3 Gut 0.75 protein_coding synonymous_variant LOW 553T>C Leu185Leu
M0191522 HFJIGMLC_00043 34390 3 Gut 0.75 protein_coding synonymous_variant LOW 531C>T Leu177Leu
M0191523 HFJIGMLC_00043 34696 3 Gut 0.75 protein_coding synonymous_variant LOW 225A>G Glu75Glu
M0191524 HFJIGMLC_00043 34730 3 Gut 0.75 protein_coding missense_variant MODERATE 191G>A Arg64Gln
M0191525 HFJIGMLC_00044 35111 3 Gut 0.75 protein_coding synonymous_variant LOW 2991C>T Thr997Thr
M0191526 HFJIGMLC_00044 35403 3 Gut 0.75 protein_coding missense_variant MODERATE 2699T>C Ile900Thr
M0191527 HFJIGMLC_00044 35546 3 Gut 0.75 protein_coding synonymous_variant LOW 2556T>C Pro852Pro
M0191528 HFJIGMLC_00044 35735 3 Gut 0.75 protein_coding synonymous_variant LOW 2367T>C Ala789Ala
M0191529 HFJIGMLC_00044 35774 3 Gut 0.75 protein_coding synonymous_variant LOW 2328G>A Pro776Pro
M0191530 HFJIGMLC_00044 35777 3 Gut 0.75 protein_coding synonymous_variant LOW 2325C>T Ala775Ala
M0191531 HFJIGMLC_00044 36056 3 Gut 0.75 protein_coding synonymous_variant LOW 2046C>T Gly682Gly
M0191532 HFJIGMLC_00044 36059 3 Gut 0.75 protein_coding synonymous_variant LOW 2043A>G Thr681Thr
M0191533 HFJIGMLC_00044 36104 3 Gut 0.75 protein_coding synonymous_variant LOW 1998G>C Pro666Pro
M0191534 HFJIGMLC_00044 36109 3 Gut 0.75 protein_coding missense_variant MODERATE 1993A>C Lys665Gln
M0191535 HFJIGMLC_00044 36164 3 Gut 0.75 protein_coding synonymous_variant LOW 1938T>C Tyr646Tyr
M0191536 HFJIGMLC_00044 36245 3 Gut 0.75 protein_coding synonymous_variant LOW 1857G>A Lys619Lys
M0191537 HFJIGMLC_00044 36307 3 Gut 0.75 protein_coding missense_variant MODERATE 1795A>G Asn599Asp
M0191538 HFJIGMLC_00044 36314 3 Gut 0.75 protein_coding synonymous_variant LOW 1788G>A Leu596Leu
M0191539 HFJIGMLC_00044 36398 3 Gut 0.75 protein_coding synonymous_variant LOW 1704T>G Ala568Ala
M0191540 HFJIGMLC_00044 36404 3 Gut 0.75 protein_coding synonymous_variant LOW 1698T>C Tyr566Tyr
M0191541 HFJIGMLC_00044 36509 3 Gut 0.75 protein_coding synonymous_variant LOW 1593A>G Thr531Thr
M0191542 HFJIGMLC_00044 36659 3 Gut 0.75 protein_coding synonymous_variant LOW 1443A>T Gly481Gly
M0191543 HFJIGMLC_00044 36761 3 Gut 0.75 protein_coding synonymous_variant LOW 1341G>A Thr447Thr
M0191544 HFJIGMLC_00044 36809 3 Gut 0.75 protein_coding synonymous_variant LOW 1293T>C Ile431Ile
M0191545 HFJIGMLC_00044 36821 3 Gut 0.75 protein_coding synonymous_variant LOW 1281T>C Thr427Thr
M0191546 HFJIGMLC_00044 36917 3 Gut 0.75 protein_coding synonymous_variant LOW 1185G>A Val395Val
M0191547 HFJIGMLC_00044 36920 3 Gut 0.75 protein_coding synonymous_variant LOW 1182A>G Arg394Arg
M0191548 HFJIGMLC_00044 37193 3 Gut 0.75 protein_coding synonymous_variant LOW 909T>G Ala303Ala
M0191549 HFJIGMLC_00044 37256 3 Gut 0.75 protein_coding synonymous_variant LOW 846T>C Gly282Gly
M0191550 HFJIGMLC_00044 37310 3 Gut 0.75 protein_coding synonymous_variant LOW 792C>T Tyr264Tyr
M0191551 HFJIGMLC_00044 37330 3 Gut 0.75 protein_coding synonymous_variant LOW 772C>T Leu258Leu
M0191552 HFJIGMLC_00044 37334 3 Gut 0.75 protein_coding synonymous_variant LOW 768A>G Gln256Gln
M0191553 HFJIGMLC_00044 37337 3 Gut 0.75 protein_coding synonymous_variant LOW 765G>T Arg255Arg
M0191554 HFJIGMLC_00044 37340 3 Gut 0.75 protein_coding synonymous_variant LOW 762G>A Glu254Glu
M0191555 HFJIGMLC_00044 37355 3 Gut 0.75 protein_coding synonymous_variant LOW 747A>G Thr249Thr
M0191556 HFJIGMLC_00044 37379 3 Gut 0.75 protein_coding synonymous_variant LOW 723T>C Ala241Ala
M0191557 HFJIGMLC_00044 37397 3 Gut 0.75 protein_coding synonymous_variant LOW 705T>C Val235Val
M0191558 HFJIGMLC_00044 37448 3 Gut 0.75 protein_coding synonymous_variant LOW 654G>A Arg218Arg
M0191559 HFJIGMLC_00044 37457 3 Gut 0.75 protein_coding synonymous_variant LOW 645T>C Phe215Phe
M0191560 HFJIGMLC_00044 37466 3 Gut 0.75 protein_coding synonymous_variant LOW 636T>C Ala212Ala
M0191561 HFJIGMLC_00044 37543 3 Gut 0.75 protein_coding synonymous_variant LOW 559T>C Leu187Leu
M0191562 HFJIGMLC_00044 37574 3 Gut 0.75 protein_coding synonymous_variant LOW 528G>A Gln176Gln
M0191563 HFJIGMLC_00044 37736 3 Gut 0.75 protein_coding synonymous_variant LOW 366G>A Arg122Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
HFJIGMLC_00020 AZP97386.1|GH73 100 0 1 818 1 0.9915
HFJIGMLC_00045 AGL62966.2|GH13_29 73.8 5.33e-153 1 302 0.9967 0.9934
HFJIGMLC_00051 QQX69612.1|GH1 100 0 1 474 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
HFJIGMLC_00035 1.A.8.2.4 100 1.4e-135 1 238 1.0000 1.0000 1 Channels/Pores 1.A α-Type Channels 1.A.8 The Major Intrinsic Protein (MIP) Family