Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C980
  Reference Plasmid   NZ_CP089340.1
  Reference Plasmid Size   3086
  Reference Plasmid GC Content   0.58
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0191564 FHFDBOOJ_00001 187 19 Gut 0.76 protein_coding downstream_gene_variant MODIFIER *308A>G None
M0191565 FHFDBOOJ_00003 1208 7 Gut 0.28 protein_coding missense_variant MODERATE 1053G>A Met351Ile
M0191566 FHFDBOOJ_00003 1241 11 Gut 0.44 protein_coding synonymous_variant LOW 1020T>C Leu340Leu
M0191567 FHFDBOOJ_00001 2611 8 Gut 0.32 protein_coding upstream_gene_variant MODIFIER -1847A>C None
M0191568 FHFDBOOJ_00001 2620 8 Gut 0.32 protein_coding upstream_gene_variant MODIFIER -1856C>G None
M0191569 FHFDBOOJ_00001 2621 8 Gut 0.32 protein_coding upstream_gene_variant MODIFIER -1857C>T None
M0191570 FHFDBOOJ_00001 2710 8 Gut 0.32 protein_coding upstream_gene_variant MODIFIER -1946A>G None
M0191571 FHFDBOOJ_00001 2711 9 Gut 0.36 protein_coding upstream_gene_variant MODIFIER -1947T>C None
M0191572 FHFDBOOJ_00004 2913 18 Gut 0.72 protein_coding synonymous_variant LOW 171A>G Lys57Lys
M0191573 FHFDBOOJ_00001 614 5 Gut 0.20 protein_coding missense_variant MODERATE 151G>T Ala51Ser
M0191574 FHFDBOOJ_00001 708 6 Gut 0.24 protein_coding synonymous_variant LOW 57T>C Asp19Asp
M0191575 FHFDBOOJ_00002 979 7 Gut 0.28 protein_coding synonymous_variant LOW 6T>C Ala2Ala
M0191576 FHFDBOOJ_00004 2906 5 Gut 0.20 protein_coding missense_variant MODERATE 178T>C Cys60Arg
M0191577 FHFDBOOJ_00004 2997 5 Gut 0.20 protein_coding synonymous_variant LOW 87C>T Pro29Pro
M0191578 FHFDBOOJ_00001 2411 6 Gut 0.24 protein_coding upstream_gene_variant MODIFIER -1647A>G None
M0191579 FHFDBOOJ_00001 2420 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -1656C>G None
M0191580 FHFDBOOJ_00003 1734 10 Gut 0.40 protein_coding missense_variant MODERATE 527G>A Arg176Gln
M0191581 FHFDBOOJ_00003 2078 9 Gut 0.36 protein_coding missense_variant MODERATE 183T>G Asp61Glu
M0191582 FHFDBOOJ_00003 1040 3 Gut 0.12 protein_coding synonymous_variant LOW 1221G>A Gly407Gly
M0191583 FHFDBOOJ_00003 1277 3 Gut 0.12 protein_coding synonymous_variant LOW 984A>G Ala328Ala
M0191584 FHFDBOOJ_00003 1679 5 Gut 0.20 protein_coding synonymous_variant LOW 582T>C Pro194Pro
M0191585 FHFDBOOJ_00003 1759 5 Gut 0.20 protein_coding missense_variant MODERATE 502C>A Gln168Lys
M0191586 FHFDBOOJ_00003 1772 5 Gut 0.20 protein_coding synonymous_variant LOW 489G>C Arg163Arg
M0191587 FHFDBOOJ_00003 1775 5 Gut 0.20 protein_coding synonymous_variant LOW 486A>G Gly162Gly
M0191588 FHFDBOOJ_00003 1781 5 Gut 0.20 protein_coding synonymous_variant LOW 480A>C Leu160Leu
M0191589 FHFDBOOJ_00003 1837 6 Gut 0.24 protein_coding synonymous_variant LOW 424T>C Leu142Leu
M0191590 FHFDBOOJ_00003 1910 4 Gut 0.16 protein_coding synonymous_variant LOW 351C>G Leu117Leu
M0191591 FHFDBOOJ_00003 1913 4 Gut 0.16 protein_coding synonymous_variant LOW 348T>C Arg116Arg
M0191592 FHFDBOOJ_00003 2003 4 Gut 0.16 protein_coding synonymous_variant LOW 258T>C Arg86Arg
M0191593 FHFDBOOJ_00003 2027 5 Gut 0.20 protein_coding synonymous_variant LOW 234G>A Glu78Glu
M0191594 FHFDBOOJ_00003 2029 4 Gut 0.16 protein_coding missense_variant MODERATE 232G>A Glu78Lys
M0191595 FHFDBOOJ_00003 2048 4 Gut 0.16 protein_coding synonymous_variant LOW 213C>T Ser71Ser
M0191596 FHFDBOOJ_00003 2171 3 Gut 0.12 protein_coding synonymous_variant LOW 90C>T Asn30Asn
M0191597 FHFDBOOJ_00003 2213 4 Gut 0.16 protein_coding synonymous_variant LOW 48T>C Leu16Leu
M0191598 FHFDBOOJ_00001 2273 4 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -1509T>C None
M0191599 FHFDBOOJ_00001 2320 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -1556C>T None
M0191600 FHFDBOOJ_00001 2436 3 Gut 0.12 protein_coding upstream_gene_variant MODIFIER -1672T>C None
M0191601 FHFDBOOJ_00003 1335 5 Gut 0.20 protein_coding missense_variant MODERATE 926A>G Gln309Arg
M0191602 FHFDBOOJ_00003 1343 3 Gut 0.12 protein_coding synonymous_variant LOW 918A>G Gly306Gly
M0191603 FHFDBOOJ_00003 1344 4 Gut 0.16 protein_coding missense_variant MODERATE 917G>A Gly306Glu
M0191604 FHFDBOOJ_00003 1348 4 Gut 0.16 protein_coding missense_variant MODERATE 913A>G Ile305Val
M0191605 FHFDBOOJ_00003 1511 5 Gut 0.20 protein_coding synonymous_variant LOW 750T>C Asn250Asn
M0191606 FHFDBOOJ_00003 1514 5 Gut 0.20 protein_coding synonymous_variant LOW 747G>A Leu249Leu
M0191607 FHFDBOOJ_00003 1517 5 Gut 0.20 protein_coding synonymous_variant LOW 744A>G Leu248Leu
M0191608 FHFDBOOJ_00003 1579 3 Gut 0.12 protein_coding missense_variant MODERATE 682G>C Glu228Gln
M0191609 FHFDBOOJ_00003 1580 3 Gut 0.12 protein_coding synonymous_variant LOW 681T>G Val227Val
M0191610 FHFDBOOJ_00003 1583 3 Gut 0.12 protein_coding synonymous_variant LOW 678G>C Val226Val
M0191611 FHFDBOOJ_00003 1586 3 Gut 0.12 protein_coding synonymous_variant LOW 675C>G Ala225Ala
M0191612 FHFDBOOJ_00003 1590 4 Gut 0.16 protein_coding missense_variant MODERATE 671A>G Lys224Arg
M0191613 FHFDBOOJ_00003 1603 3 Gut 0.12 protein_coding missense_variant MODERATE 658T>G Cys220Gly
M0191614 FHFDBOOJ_00003 1640 4 Gut 0.16 protein_coding synonymous_variant LOW 621A>T Val207Val
M0191615 FHFDBOOJ_00003 1643 3 Gut 0.12 protein_coding synonymous_variant LOW 618T>C Arg206Arg
M0191616 FHFDBOOJ_00001 451 3 Gut 0.12 protein_coding downstream_gene_variant MODIFIER *44G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term