Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C993
  Reference Plasmid   NZ_CP090943.1
  Reference Plasmid Size   14665
  Reference Plasmid GC Content   0.29
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0105839 DPGACEOB_00003 2499 4 Skin 0.05 protein_coding missense_variant MODERATE 1240C>T Pro414Ser
M0105840 DPGACEOB_00002 3738 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -2861G>A None
M0105841 DPGACEOB_00005 4459 4 Skin 0.05 protein_coding synonymous_variant LOW 489T>C Ile163Ile
M0105842 DPGACEOB_00005 4484 4 Skin 0.05 protein_coding missense_variant MODERATE 514A>G Ile172Val
M0105843 DPGACEOB_00005 4553 5 Skin 0.06 protein_coding missense_variant MODERATE 583G>A Ala195Thr
M0105844 DPGACEOB_00005 4831 17 Skin 0.21 protein_coding synonymous_variant LOW 861A>G Glu287Glu
M0105845 DPGACEOB_00006 5400 13 Skin 0.16 protein_coding synonymous_variant LOW 487C>T Leu163Leu
M0105846 DPGACEOB_00007 6835 33 Skin 0.41 protein_coding synonymous_variant LOW 540T>C Asn180Asn
M0105847 DPGACEOB_00008 7808 27 Skin 0.34 protein_coding missense_variant MODERATE 1765C>T His589Tyr
M0105848 DPGACEOB_00008 9388 23 Skin 0.29 protein_coding missense_variant MODERATE 185C>T Thr62Ile
M0105849 DPGACEOB_00006 9677 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -3791T>C None
M0105850 DPGACEOB_00006 9970 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -4084T>A None
M0105851 DPGACEOB_00006 9983 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -4097G>A None
M0105852 DPGACEOB_00006 5604 8 Skin 0.10 protein_coding synonymous_variant LOW 283T>C Leu95Leu
M0105853 DPGACEOB_00004 5959 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -2496C>T None
M0105854 DPGACEOB_00004 6005 11 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -2542T>C None
M0105855 DPGACEOB_00007 6105 8 Skin 0.10 protein_coding missense_variant MODERATE 1270C>G Leu424Val
M0105856 DPGACEOB_00002 3487 11 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -2610G>T None
M0105857 DPGACEOB_00002 3907 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3030G>A None
M0105858 DPGACEOB_00008 8052 8 Skin 0.10 protein_coding synonymous_variant LOW 1521C>A Gly507Gly
M0105859 DPGACEOB_00008 8281 7 Skin 0.09 protein_coding missense_variant MODERATE 1292C>T Thr431Ile
M0105860 DPGACEOB_00006 5032 4 Skin 0.05 protein_coding synonymous_variant LOW 855C>T Phe285Phe
M0105861 DPGACEOB_00006 5035 4 Skin 0.05 protein_coding synonymous_variant LOW 852T>C Asn284Asn
M0105862 DPGACEOB_00006 5108 5 Skin 0.06 protein_coding missense_variant MODERATE 779G>A Arg260Lys
M0105863 DPGACEOB_00006 5200 3 Skin 0.04 protein_coding synonymous_variant LOW 687A>G Lys229Lys
M0105864 DPGACEOB_00006 5527 5 Skin 0.06 protein_coding synonymous_variant LOW 360A>C Gly120Gly
M0105865 DPGACEOB_00006 5668 4 Skin 0.05 protein_coding synonymous_variant LOW 219A>G Gly73Gly
M0105866 DPGACEOB_00007 6400 3 Skin 0.04 protein_coding synonymous_variant LOW 975A>G Val325Val
M0105867 DPGACEOB_00003 2306 3 Skin 0.04 protein_coding synonymous_variant LOW 1047T>C Asn349Asn
M0105868 DPGACEOB_00003 2330 3 Skin 0.04 protein_coding synonymous_variant LOW 1071A>G Gly357Gly
M0105869 DPGACEOB_00003 1998 4 Skin 0.05 protein_coding missense_variant MODERATE 739G>C Asp247His
M0105870 DPGACEOB_00003 2520 8 Skin 0.10 protein_coding missense_variant MODERATE 1261G>A Asp421Asn
M0105871 DPGACEOB_00002 2610 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -1733T>C None
M0105872 DPGACEOB_00002 2667 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -1790G>A None
M0105873 DPGACEOB_00002 2714 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -1837C>T None
M0105874 DPGACEOB_00002 2731 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -1854C>T None
M0105875 DPGACEOB_00002 2750 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -1873G>A None
M0105876 DPGACEOB_00002 2794 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1917C>T None
M0105877 DPGACEOB_00002 2795 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1918A>T None
M0105878 DPGACEOB_00002 2796 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1919A>T None
M0105879 DPGACEOB_00002 2799 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1922A>T None
M0105880 DPGACEOB_00002 2800 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1923A>T None
M0105881 DPGACEOB_00002 2801 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1924A>G None
M0105882 DPGACEOB_00002 2862 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -1985C>T None
M0105883 DPGACEOB_00002 2908 9 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -2031C>T None
M0105884 DPGACEOB_00002 2912 8 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -2035T>C None
M0105885 DPGACEOB_00002 2918 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -2041G>A None
M0105886 DPGACEOB_00002 3065 5 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -2188A>T None
M0105887 DPGACEOB_00002 3066 5 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -2189C>A None
M0105888 DPGACEOB_00002 3068 8 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -2191G>A None
M0105889 DPGACEOB_00002 3069 5 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -2192T>G None
M0105890 DPGACEOB_00002 3070 5 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -2193A>T None
M0105891 DPGACEOB_00005 4557 4 Skin 0.05 protein_coding missense_variant MODERATE 587T>C Ile196Thr
M0105892 DPGACEOB_00007 12003 10 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -4629T>C None
M0105893 DPGACEOB_00002 3251 8 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -2374A>G None
M0105894 DPGACEOB_00002 3254 8 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -2377A>T None
M0105895 DPGACEOB_00002 3255 8 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -2378A>T None
M0105896 DPGACEOB_00002 3258 8 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -2381C>T None
M0105897 DPGACEOB_00002 3304 8 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -2427A>G None
M0105898 DPGACEOB_00004 3370 9 Skin 0.11 protein_coding missense_variant MODERATE 94G>A Asp32Asn
M0105899 DPGACEOB_00002 3625 6 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2748C>A None
M0105900 DPGACEOB_00002 3930 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -3053G>A None
M0105901 DPGACEOB_00009 10871 10 Skin 0.13 protein_coding synonymous_variant LOW 643T>C Leu215Leu
M0105902 DPGACEOB_00002 569 4 Skin 0.05 protein_coding synonymous_variant LOW 309T>C His103His
M0105903 DPGACEOB_00002 578 4 Skin 0.05 protein_coding synonymous_variant LOW 300T>C Val100Val
M0105904 DPGACEOB_00002 619 4 Skin 0.05 protein_coding synonymous_variant LOW 259C>T Leu87Leu
M0105905 DPGACEOB_00002 632 4 Skin 0.05 protein_coding missense_variant MODERATE 246A>T Gln82His
M0105906 DPGACEOB_00002 650 3 Skin 0.04 protein_coding synonymous_variant LOW 228T>C Asn76Asn
M0105907 DPGACEOB_00002 916 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -39G>A None
M0105908 DPGACEOB_00002 1063 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -186G>T None
M0105909 DPGACEOB_00002 1094 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -217T>C None
M0105910 DPGACEOB_00003 1514 3 Skin 0.04 protein_coding synonymous_variant LOW 255C>T Tyr85Tyr
M0105911 DPGACEOB_00003 1608 3 Skin 0.04 protein_coding missense_variant MODERATE 349A>G Lys117Glu
M0105912 DPGACEOB_00003 1610 3 Skin 0.04 protein_coding synonymous_variant LOW 351G>A Lys117Lys
M0105913 DPGACEOB_00003 1613 3 Skin 0.04 protein_coding synonymous_variant LOW 354G>A Thr118Thr
M0105914 DPGACEOB_00003 1790 3 Skin 0.04 protein_coding synonymous_variant LOW 531T>C Ala177Ala
M0105915 DPGACEOB_00003 1794 3 Skin 0.04 protein_coding missense_variant MODERATE 535A>C Asn179His
M0105916 DPGACEOB_00009 10520 6 Skin 0.08 protein_coding missense_variant MODERATE 292C>T Pro98Ser
M0105917 DPGACEOB_00007 11415 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -4041A>G None
M0105918 DPGACEOB_00006 10185 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -4299G>T None
M0105919 DPGACEOB_00002 3098 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -2221C>A None
M0105920 DPGACEOB_00006 5809 3 Skin 0.04 protein_coding synonymous_variant LOW 78A>G Gly26Gly
M0105921 DPGACEOB_00002 900 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -23C>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term