Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1001
  Reference Plasmid   NZ_CP093166.1
  Reference Plasmid Size   25527
  Reference Plasmid GC Content   0.29
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0106256 GBNHFBGD_00010 13983 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -4241A>T None
M0106257 GBNHFBGD_00010 14004 6 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -4262C>A None
M0106258 GBNHFBGD_00010 14005 6 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -4263C>G None
M0106259 GBNHFBGD_00010 14143 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -4401C>T None
M0106260 GBNHFBGD_00012 16276 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -4452G>T None
M0106261 GBNHFBGD_00012 16292 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -4468A>G None
M0106262 GBNHFBGD_00012 16299 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -4475T>C None
M0106263 GBNHFBGD_00012 16342 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -4518G>A None
M0106264 GBNHFBGD_00012 16567 10 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -4743T>C None
M0106265 GBNHFBGD_00012 16600 10 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -4776C>T None
M0106266 GBNHFBGD_00012 16629 10 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -4805G>A None
M0106267 GBNHFBGD_00012 16687 10 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -4863A>G None
M0106268 GBNHFBGD_00020 17631 4 Skin 0.07 protein_coding missense_variant MODERATE 739G>A Ala247Thr
M0106269 GBNHFBGD_00020 18199 3 Skin 0.05 protein_coding synonymous_variant LOW 171C>T Tyr57Tyr
M0106270 GBNHFBGD_00021 18860 3 Skin 0.05 protein_coding synonymous_variant LOW 339T>C Cys113Cys
M0106271 GBNHFBGD_00016 14554 6 Skin 0.10 protein_coding synonymous_variant LOW 687T>C His229His
M0106272 GBNHFBGD_00004 4643 13 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -1712G>A None
M0106273 GBNHFBGD_00004 5341 4 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -2410T>C None
M0106274 GBNHFBGD_00016 14677 5 Skin 0.08 protein_coding synonymous_variant LOW 564C>T Ser188Ser
M0106275 GBNHFBGD_00016 14791 3 Skin 0.05 protein_coding synonymous_variant LOW 450T>C Asn150Asn
M0106276 GBNHFBGD_00016 14890 5 Skin 0.08 protein_coding synonymous_variant LOW 351G>A Pro117Pro
M0106277 GBNHFBGD_00016 14992 5 Skin 0.08 protein_coding synonymous_variant LOW 249A>G Lys83Lys
M0106278 GBNHFBGD_00016 15235 3 Skin 0.05 protein_coding missense_variant MODERATE 6G>T Lys2Asn
M0106279 GBNHFBGD_00012 15255 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -3431G>A None
M0106280 GBNHFBGD_00012 15268 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3444T>C None
M0106281 GBNHFBGD_00012 15296 4 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -3472A>T None
M0106282 GBNHFBGD_00012 15298 4 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -3474T>A None
M0106283 GBNHFBGD_00012 15299 4 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -3475A>T None
M0106284 GBNHFBGD_00012 15301 4 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -3477T>A None
M0106285 GBNHFBGD_00017 15350 3 Skin 0.05 protein_coding missense_variant MODERATE 28A>G Thr10Ala
M0106286 GBNHFBGD_00017 15354 3 Skin 0.05 protein_coding missense_variant MODERATE 32C>T Ser11Phe
M0106287 GBNHFBGD_00017 15358 3 Skin 0.05 protein_coding synonymous_variant LOW 36T>A Ile12Ile
M0106288 GBNHFBGD_00017 15383 3 Skin 0.05 protein_coding missense_variant MODERATE 61G>A Val21Ile
M0106289 GBNHFBGD_00020 18127 3 Skin 0.05 protein_coding synonymous_variant LOW 243A>G Val81Val
M0106290 GBNHFBGD_00019 17115 8 Skin 0.13 protein_coding missense_variant MODERATE 269A>G Asn90Ser
M0106291 GBNHFBGD_00016 17593 9 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -2353T>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
GBNHFBGD_00001 ARO:3004674 100 5.08e-106 1 139 1.0000 1.0000 phosphonic acid antibiotic fosfomycin thiol transferase antibiotic inactivation
EOHLHOME_00001 ARO:3004674 100 5.08e-106 1 139 1.0000 1.0000 phosphonic acid antibiotic fosfomycin thiol transferase antibiotic inactivation






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term