Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1014
  Reference Plasmid   NZ_CP095095.1
  Reference Plasmid Size   21828
  Reference Plasmid GC Content   0.48
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0191775 MMEGHKIF_00007 8457 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -4948A>T None
M0191776 MMEGHKIF_00007 8458 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -4949T>A None
M0191777 MMEGHKIF_00007 8459 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -4950A>T None
M0191778 MMEGHKIF_00007 8460 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -4951C>T None
M0191779 MMEGHKIF_00007 8464 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -4955C>T None
M0191780 MMEGHKIF_00007 8479 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -4970G>A None
M0191781 MMEGHKIF_00007 8482 5 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -4973G>C None
M0191782 MMEGHKIF_00007 8486 4 Gut 0.31 protein_coding upstream_gene_variant MODIFIER -4977T>C None
M0191783 MMEGHKIF_00007 8494 4 Gut 0.31 protein_coding upstream_gene_variant MODIFIER -4985A>G None
M0191784 MMEGHKIF_00012 11852 3 Gut 0.23 protein_coding upstream_gene_variant MODIFIER -4080G>A None
M0191785 MMEGHKIF_00012 6843 3 Gut 0.23 protein_coding synonymous_variant LOW 930G>A Arg310Arg
M0191786 MMEGHKIF_00012 6888 4 Gut 0.31 protein_coding synonymous_variant LOW 885A>G Arg295Arg
M0191787 MMEGHKIF_00012 6890 4 Gut 0.31 protein_coding synonymous_variant LOW 883A>C Arg295Arg
M0191788 MMEGHKIF_00012 6893 4 Gut 0.31 protein_coding missense_variant MODERATE 880T>C Cys294Arg
M0191789 MMEGHKIF_00012 6927 4 Gut 0.31 protein_coding synonymous_variant LOW 846C>T Asp282Asp
M0191790 MMEGHKIF_00012 6975 4 Gut 0.31 protein_coding synonymous_variant LOW 798G>C Ala266Ala
M0191791 MMEGHKIF_00012 7020 3 Gut 0.23 protein_coding synonymous_variant LOW 753G>A Val251Val
M0191792 MMEGHKIF_00012 7032 4 Gut 0.31 protein_coding synonymous_variant LOW 741T>C Gly247Gly
M0191793 MMEGHKIF_00012 7075 4 Gut 0.31 protein_coding missense_variant MODERATE 698A>C Gln233Pro
M0191794 MMEGHKIF_00012 7089 4 Gut 0.31 protein_coding synonymous_variant LOW 684T>C Ser228Ser
M0191795 MMEGHKIF_00012 7110 4 Gut 0.31 protein_coding synonymous_variant LOW 663G>A Lys221Lys
M0191796 MMEGHKIF_00012 7151 3 Gut 0.23 protein_coding missense_variant MODERATE 622A>T Met208Leu
M0191797 MMEGHKIF_00012 7154 4 Gut 0.31 protein_coding synonymous_variant LOW 619A>C Arg207Arg
M0191798 MMEGHKIF_00012 7215 4 Gut 0.31 protein_coding synonymous_variant LOW 558T>C Ser186Ser
M0191799 MMEGHKIF_00012 7224 4 Gut 0.31 protein_coding synonymous_variant LOW 549T>C Ser183Ser
M0191800 MMEGHKIF_00012 7254 3 Gut 0.23 protein_coding synonymous_variant LOW 519C>T Ser173Ser
M0191801 MMEGHKIF_00012 7255 4 Gut 0.31 protein_coding missense_variant MODERATE 518G>C Ser173Thr
M0191802 MMEGHKIF_00012 7299 3 Gut 0.23 protein_coding synonymous_variant LOW 474G>A Leu158Leu
M0191803 MMEGHKIF_00012 7308 4 Gut 0.31 protein_coding synonymous_variant LOW 465T>G Gly155Gly
M0191804 MMEGHKIF_00012 7434 3 Gut 0.23 protein_coding synonymous_variant LOW 339C>T Asp113Asp
M0191805 MMEGHKIF_00012 7446 3 Gut 0.23 protein_coding synonymous_variant LOW 327T>C Gly109Gly
M0191806 MMEGHKIF_00012 7458 3 Gut 0.23 protein_coding synonymous_variant LOW 315A>C Gly105Gly
M0191807 MMEGHKIF_00012 7476 3 Gut 0.23 protein_coding synonymous_variant LOW 297G>A Leu99Leu
M0191808 MMEGHKIF_00012 7478 4 Gut 0.31 protein_coding synonymous_variant LOW 295C>T Leu99Leu
M0191809 MMEGHKIF_00012 7509 3 Gut 0.23 protein_coding synonymous_variant LOW 264C>T Ala88Ala
M0191810 MMEGHKIF_00012 7521 3 Gut 0.23 protein_coding synonymous_variant LOW 252G>A Leu84Leu
M0191811 MMEGHKIF_00012 7557 3 Gut 0.23 protein_coding synonymous_variant LOW 216A>G Thr72Thr
M0191812 MMEGHKIF_00012 7617 4 Gut 0.31 protein_coding synonymous_variant LOW 156T>C Tyr52Tyr
M0191813 MMEGHKIF_00012 7629 3 Gut 0.23 protein_coding synonymous_variant LOW 144C>T Thr48Thr
M0191814 MMEGHKIF_00012 7669 3 Gut 0.23 protein_coding missense_variant MODERATE 104C>T Ala35Val
M0191815 MMEGHKIF_00012 7671 4 Gut 0.31 protein_coding synonymous_variant LOW 102A>G Val34Val
M0191816 MMEGHKIF_00012 7683 4 Gut 0.31 protein_coding synonymous_variant LOW 90G>A Lys30Lys
M0191817 MMEGHKIF_00012 7686 4 Gut 0.31 protein_coding synonymous_variant LOW 87T>C Ser29Ser
M0191818 MMEGHKIF_00012 7692 4 Gut 0.31 protein_coding synonymous_variant LOW 81T>G Gly27Gly
M0191819 MMEGHKIF_00012 7695 3 Gut 0.23 protein_coding synonymous_variant LOW 78C>T Phe26Phe
M0191820 MMEGHKIF_00012 7719 4 Gut 0.31 protein_coding synonymous_variant LOW 54T>C Asp18Asp
M0191821 MMEGHKIF_00025 15553 3 Gut 0.23 protein_coding missense_variant MODERATE 188G>A Arg63Gln






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term