Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1015
  Reference Plasmid   NZ_CP095105.1
  Reference Plasmid Size   36154
  Reference Plasmid GC Content   0.31
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0106647 BMGGOLPK_00028 17482 4 Skin 0.44 protein_coding synonymous_variant LOW 258C>T Cys86Cys
M0106648 BMGGOLPK_00028 17512 4 Skin 0.44 protein_coding synonymous_variant LOW 288G>T Thr96Thr
M0106649 BMGGOLPK_00028 17839 4 Skin 0.44 protein_coding synonymous_variant LOW 615C>T Ser205Ser
M0106650 BMGGOLPK_00028 17999 3 Skin 0.33 protein_coding missense_variant MODERATE 775G>A Ala259Thr
M0106651 BMGGOLPK_00028 18004 4 Skin 0.44 protein_coding synonymous_variant LOW 780C>T Tyr260Tyr
M0106652 BMGGOLPK_00007 7554 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -2622A>C None
M0106653 BMGGOLPK_00007 7582 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -2650G>A None
M0106654 BMGGOLPK_00014 7610 4 Skin 0.44 protein_coding missense_variant MODERATE 1545A>T Lys515Asn
M0106655 BMGGOLPK_00014 7758 4 Skin 0.44 protein_coding missense_variant MODERATE 1397T>A Phe466Tyr
M0106656 BMGGOLPK_00014 7811 4 Skin 0.44 protein_coding synonymous_variant LOW 1344T>C Ala448Ala
M0106657 BMGGOLPK_00014 7913 4 Skin 0.44 protein_coding synonymous_variant LOW 1242C>T Phe414Phe
M0106658 BMGGOLPK_00014 7936 4 Skin 0.44 protein_coding missense_variant MODERATE 1219A>G Ile407Val
M0106659 BMGGOLPK_00014 8193 4 Skin 0.44 protein_coding missense_variant MODERATE 962A>G Glu321Gly
M0106660 BMGGOLPK_00014 8267 3 Skin 0.33 protein_coding synonymous_variant LOW 888C>T Arg296Arg
M0106661 BMGGOLPK_00014 8444 4 Skin 0.44 protein_coding synonymous_variant LOW 711C>T Ser237Ser
M0106662 BMGGOLPK_00014 8497 4 Skin 0.44 protein_coding missense_variant MODERATE 658G>A Ala220Thr
M0106663 BMGGOLPK_00014 8508 3 Skin 0.33 protein_coding missense_variant MODERATE 647A>G Lys216Arg
M0106664 BMGGOLPK_00014 8512 3 Skin 0.33 protein_coding missense_variant MODERATE 643G>A Gly215Ser
M0106665 BMGGOLPK_00014 8520 4 Skin 0.44 protein_coding missense_variant MODERATE 635T>C Leu212Ser
M0106666 BMGGOLPK_00014 8771 4 Skin 0.44 protein_coding synonymous_variant LOW 384T>A Ala128Ala
M0106667 BMGGOLPK_00014 8895 4 Skin 0.44 protein_coding missense_variant MODERATE 260T>G Leu87Arg
M0106668 BMGGOLPK_00014 8957 4 Skin 0.44 protein_coding synonymous_variant LOW 198C>T His66His
M0106669 BMGGOLPK_00007 9254 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -4322A>G None
M0106670 BMGGOLPK_00007 9326 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -4394C>T None
M0106671 BMGGOLPK_00007 9436 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -4504G>T None
M0106672 BMGGOLPK_00028 17323 3 Skin 0.33 protein_coding synonymous_variant LOW 99G>A Gly33Gly
M0106673 BMGGOLPK_00028 17377 3 Skin 0.33 protein_coding synonymous_variant LOW 153T>G Gly51Gly
M0106674 BMGGOLPK_00029 18508 3 Skin 0.33 protein_coding missense_variant MODERATE 478T>C Tyr160His
M0106675 BMGGOLPK_00029 18726 3 Skin 0.33 protein_coding synonymous_variant LOW 696A>G Ser232Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
BMGGOLPK_00014 ARO:3002829 97.9 0 1 522 1.0000 1.0000 lincosamide antibiotic vga-type ABC-F protein antibiotic target protection






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
BMGGOLPK_00014 3.A.1.121.5 97.1 2.6e-283 1 522 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily