Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1026
  Reference Plasmid   NZ_CP096968.1
  Reference Plasmid Size   11693
  Reference Plasmid GC Content   0.38
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0192526 IFLMFNNK_00004 1982 4 Gut 0.18 protein_coding synonymous_variant LOW 156A>G Gln52Gln
M0192527 IFLMFNNK_00004 2027 4 Gut 0.18 protein_coding synonymous_variant LOW 201A>G Leu67Leu
M0192528 IFLMFNNK_00004 2039 4 Gut 0.18 protein_coding synonymous_variant LOW 213C>A Ala71Ala
M0192529 IFLMFNNK_00004 2042 4 Gut 0.18 protein_coding synonymous_variant LOW 216C>T Asn72Asn
M0192530 IFLMFNNK_00004 2043 4 Gut 0.18 protein_coding missense_variant MODERATE 217T>C Tyr73His
M0192531 IFLMFNNK_00004 2049 4 Gut 0.18 protein_coding missense_variant MODERATE 223G>A Val75Ile
M0192532 IFLMFNNK_00004 2060 4 Gut 0.18 protein_coding synonymous_variant LOW 234C>T Tyr78Tyr
M0192533 IFLMFNNK_00004 2068 4 Gut 0.18 protein_coding missense_variant MODERATE 242C>A Pro81His
M0192534 IFLMFNNK_00004 2069 5 Gut 0.23 protein_coding synonymous_variant LOW 243C>T Pro81Pro
M0192535 IFLMFNNK_00004 2074 4 Gut 0.18 protein_coding missense_variant MODERATE 248A>G Glu83Gly
M0192536 IFLMFNNK_00004 2075 4 Gut 0.18 protein_coding synonymous_variant LOW 249A>G Glu83Glu
M0192537 IFLMFNNK_00004 2076 4 Gut 0.18 protein_coding missense_variant MODERATE 250G>T Val84Leu
M0192538 IFLMFNNK_00004 2256 5 Gut 0.23 protein_coding synonymous_variant LOW 430C>T Leu144Leu
M0192539 IFLMFNNK_00004 2297 5 Gut 0.23 protein_coding synonymous_variant LOW 471C>T Asn157Asn
M0192540 IFLMFNNK_00004 2312 5 Gut 0.23 protein_coding synonymous_variant LOW 486C>T Ile162Ile
M0192541 IFLMFNNK_00004 2287 3 Gut 0.14 protein_coding missense_variant MODERATE 461G>A Arg154His
M0192542 IFLMFNNK_00004 2343 3 Gut 0.14 protein_coding missense_variant MODERATE 517G>A Glu173Lys
M0192543 IFLMFNNK_00004 2389 3 Gut 0.14 protein_coding missense_variant MODERATE 563C>T Thr188Met
M0192544 IFLMFNNK_00004 2399 3 Gut 0.14 protein_coding synonymous_variant LOW 573T>C Ser191Ser
M0192545 IFLMFNNK_00004 2822 3 Gut 0.14 protein_coding synonymous_variant LOW 996G>A Arg332Arg
M0192546 IFLMFNNK_00004 3032 3 Gut 0.14 protein_coding synonymous_variant LOW 1206A>G Glu402Glu
M0192547 IFLMFNNK_00004 3035 3 Gut 0.14 protein_coding synonymous_variant LOW 1209C>A Gly403Gly
M0192548 IFLMFNNK_00004 3062 3 Gut 0.14 protein_coding synonymous_variant LOW 1236A>G Lys412Lys
M0192549 IFLMFNNK_00004 3071 3 Gut 0.14 protein_coding synonymous_variant LOW 1245C>T Ile415Ile
M0192550 IFLMFNNK_00004 3087 3 Gut 0.14 protein_coding missense_variant MODERATE 1261A>G Ile421Val
M0192551 IFLMFNNK_00004 3104 3 Gut 0.14 protein_coding synonymous_variant LOW 1278A>G Ala426Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term