Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1033
  Reference Plasmid   NZ_CP098224.1
  Reference Plasmid Size   102981
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0193113 IGNOHBMO_00126 95168 3 Gut 0.16 protein_coding missense_variant MODERATE 161G>A Arg54His
M0193114 IGNOHBMO_00126 95204 3 Gut 0.16 protein_coding missense_variant MODERATE 125T>A Leu42His
M0193115 IGNOHBMO_00126 95227 3 Gut 0.16 protein_coding synonymous_variant LOW 102C>T Cys34Cys
M0193116 IGNOHBMO_00127 95611 3 Gut 0.16 protein_coding missense_variant MODERATE 182T>G Ile61Ser
M0193117 IGNOHBMO_00116 95891 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4938T>C None
M0193118 IGNOHBMO_00117 96021 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4444C>T None
M0193119 IGNOHBMO_00117 96028 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4451G>A None
M0193120 IGNOHBMO_00117 96108 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4531T>C None
M0193121 IGNOHBMO_00128 96186 3 Gut 0.16 protein_coding synonymous_variant LOW 72A>G Pro24Pro
M0193122 IGNOHBMO_00128 96254 3 Gut 0.16 protein_coding missense_variant MODERATE 140G>A Arg47His
M0193123 IGNOHBMO_00128 96392 3 Gut 0.16 protein_coding missense_variant MODERATE 278A>C Glu93Ala
M0193124 IGNOHBMO_00128 96472 3 Gut 0.16 protein_coding synonymous_variant LOW 358C>A Arg120Arg
M0193125 IGNOHBMO_00128 96478 3 Gut 0.16 protein_coding synonymous_variant LOW 364T>C Leu122Leu
M0193126 IGNOHBMO_00128 96490 3 Gut 0.16 protein_coding missense_variant MODERATE 376T>G Cys126Gly
M0193127 IGNOHBMO_00118 96805 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4473T>C None
M0193128 IGNOHBMO_00118 96824 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4492T>A None
M0193129 IGNOHBMO_00118 97057 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4725A>G None
M0193130 IGNOHBMO_00118 97079 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4747A>T None
M0193131 IGNOHBMO_00130 97369 3 Gut 0.16 protein_coding missense_variant MODERATE 173G>A Arg58His
M0193132 IGNOHBMO_00130 97476 3 Gut 0.16 protein_coding missense_variant MODERATE 66T>G Cys22Trp
M0193133 IGNOHBMO_00120 97627 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4550A>C None
M0193134 IGNOHBMO_00134 99597 3 Gut 0.16 protein_coding missense_variant MODERATE 601T>A Ser201Thr
M0193135 IGNOHBMO_00134 99655 3 Gut 0.16 protein_coding synonymous_variant LOW 543G>T Leu181Leu
M0193136 IGNOHBMO_00134 99946 3 Gut 0.16 protein_coding synonymous_variant LOW 252A>G Gln84Gln
M0193137 IGNOHBMO_00135 100341 3 Gut 0.16 protein_coding synonymous_variant LOW 1062A>G Glu354Glu
M0193138 IGNOHBMO_00135 101061 5 Gut 0.26 protein_coding synonymous_variant LOW 342C>T Cys114Cys
M0193139 IGNOHBMO_00135 101250 5 Gut 0.26 protein_coding synonymous_variant LOW 153A>G Lys51Lys
M0193140 IGNOHBMO_00136 102055 4 Gut 0.21 protein_coding synonymous_variant LOW 42C>G Leu14Leu
M0193141 IGNOHBMO_00001 274 3 Gut 0.16 protein_coding missense_variant MODERATE 167A>G Asn56Ser
M0193142 IGNOHBMO_00136 102060 3 Gut 0.16 protein_coding missense_variant MODERATE 37T>G Tyr13Asp
M0193143 IGNOHBMO_00130 102352 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4811G>A None
M0193144 IGNOHBMO_00130 102443 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4902T>G None
M0193145 IGNOHBMO_00130 102450 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4909T>C None
M0193146 IGNOHBMO_00131 102792 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4691T>C None
M0193147 IGNOHBMO_00131 102864 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4763G>C None
M0193148 IGNOHBMO_00131 102878 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4777C>T None
M0193149 IGNOHBMO_00131 102933 3 Gut 0.16 protein_coding upstream_gene_variant MODIFIER -4832A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
IGNOHBMO_00080 VFG034574 Dispersin 95.7 1.1e-60 1 116 1.0 1 Others dispersin experiment
IGNOHBMO_00035 VFG035924 Dispersin 82.2 1.2e-93 1 208 1.0 1 Others ATP-binding protein AatC prediction
IGNOHBMO_00036 VFG035918 Dispersin 82.7 2e-119 1 255 1.0 1 Others AatB prediction
IGNOHBMO_00037 VFG035911 Dispersin 80 1.9e-177 1 400 1.0 1 Others outer membrane protein AatA prediction
IGNOHBMO_00038 VFG035904 Dispersin 83.4 2.1e-162 6 377 0.9867 0.9841 Others permease AatP prediction
IGNOHBMO_00080 VFG034574 Dispersin 95.7 8e-60 1 116 1.0 1 Others dispersin prediction
IGNOHBMO_00087 VFG035359 AAI/SCI-II T6SS 80.1 2.2e-236 1 492 1.0 1 Effector delivery system type VI secretion system contractile sheath large subunit prediction
IGNOHBMO_00094 VFG035394 AAI/SCI-II T6SS 72.7 5.1e-39 1 99 1.0 1 Effector delivery system PAAR domain-containing protein prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
IGNOHBMO_00067 1.E.53.1.11 97.1 2.9e-32 36 103 0.6602 1.0000 1 Channels/Pores 1.E Holins 1.E.53 The Toxic Hok/Gef Protein (Hok/Gef) Family