Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1042
  Reference Plasmid   NZ_CP102520.1
  Reference Plasmid Size   214958
  Reference Plasmid GC Content   0.32
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0193425 GLGNFEBA_00204 177619 3 Gut 0.60 protein_coding synonymous_variant LOW 1467C>T Asn489Asn
M0193426 GLGNFEBA_00204 177775 3 Gut 0.60 protein_coding synonymous_variant LOW 1623G>A Ala541Ala
M0193427 GLGNFEBA_00204 177826 3 Gut 0.60 protein_coding synonymous_variant LOW 1674G>A Leu558Leu
M0193428 GLGNFEBA_00204 177883 3 Gut 0.60 protein_coding synonymous_variant LOW 1731G>A Gly577Gly
M0193429 GLGNFEBA_00205 178307 3 Gut 0.60 protein_coding synonymous_variant LOW 228T>C Val76Val
M0193430 GLGNFEBA_00206 178780 3 Gut 0.60 protein_coding synonymous_variant LOW 366C>T Tyr122Tyr
M0193431 GLGNFEBA_00206 178881 3 Gut 0.60 protein_coding missense_variant MODERATE 467C>T Ser156Leu
M0193432 GLGNFEBA_00206 179305 3 Gut 0.60 protein_coding synonymous_variant LOW 891C>T Gly297Gly
M0193433 GLGNFEBA_00206 179362 3 Gut 0.60 protein_coding synonymous_variant LOW 948C>T Val316Val
M0193434 GLGNFEBA_00207 179732 3 Gut 0.60 protein_coding missense_variant MODERATE 97G>A Ala33Thr
M0193435 GLGNFEBA_00207 179743 3 Gut 0.60 protein_coding synonymous_variant LOW 108G>A Glu36Glu
M0193436 GLGNFEBA_00207 179848 3 Gut 0.60 protein_coding synonymous_variant LOW 213G>A Val71Val
M0193437 GLGNFEBA_00207 179887 3 Gut 0.60 protein_coding synonymous_variant LOW 252C>T Gly84Gly
M0193438 GLGNFEBA_00207 180070 3 Gut 0.60 protein_coding synonymous_variant LOW 435C>T His145His
M0193439 GLGNFEBA_00207 180106 3 Gut 0.60 protein_coding synonymous_variant LOW 471G>A Glu157Glu
M0193440 GLGNFEBA_00207 180118 3 Gut 0.60 protein_coding synonymous_variant LOW 483A>G Glu161Glu
M0193441 GLGNFEBA_00207 180154 3 Gut 0.60 protein_coding synonymous_variant LOW 519T>C His173His
M0193442 GLGNFEBA_00208 180242 3 Gut 0.60 protein_coding missense_variant MODERATE 14A>T Asn5Ile
M0193443 GLGNFEBA_00208 180283 3 Gut 0.60 protein_coding missense_variant MODERATE 55G>C Val19Leu
M0193444 GLGNFEBA_00208 180333 3 Gut 0.60 protein_coding synonymous_variant LOW 105C>T Thr35Thr
M0193445 GLGNFEBA_00208 180611 3 Gut 0.60 protein_coding missense_variant MODERATE 383G>T Gly128Val
M0193446 GLGNFEBA_00208 180797 3 Gut 0.60 protein_coding missense_variant MODERATE 569T>G Ile190Ser
M0193447 GLGNFEBA_00209 181269 3 Gut 0.60 protein_coding synonymous_variant LOW 264C>T Ser88Ser
M0193448 GLGNFEBA_00209 181395 3 Gut 0.60 protein_coding missense_variant MODERATE 390G>A Met130Ile
M0193449 GLGNFEBA_00209 181402 3 Gut 0.60 protein_coding missense_variant MODERATE 397T>C Ser133Pro
M0193450 GLGNFEBA_00209 181980 3 Gut 0.60 protein_coding synonymous_variant LOW 975G>A Lys325Lys
M0193451 GLGNFEBA_00210 182504 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -455T>C None
M0193452 GLGNFEBA_00210 182518 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -441A>G None
M0193453 GLGNFEBA_00210 182585 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -374G>T None
M0193454 GLGNFEBA_00210 182589 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -370G>A None
M0193455 GLGNFEBA_00210 182633 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -326A>G None
M0193456 GLGNFEBA_00210 182689 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -270T>C None
M0193457 GLGNFEBA_00210 182718 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -241G>A None
M0193458 GLGNFEBA_00210 182734 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -225C>T None
M0193459 GLGNFEBA_00210 183000 3 Gut 0.60 protein_coding synonymous_variant LOW 42T>C Ser14Ser
M0193460 GLGNFEBA_00210 183030 3 Gut 0.60 protein_coding synonymous_variant LOW 72T>A Gly24Gly
M0193461 GLGNFEBA_00210 183036 3 Gut 0.60 protein_coding synonymous_variant LOW 78A>T Ser26Ser
M0193462 GLGNFEBA_00210 183054 3 Gut 0.60 protein_coding synonymous_variant LOW 96G>A Lys32Lys
M0193463 GLGNFEBA_00210 183087 3 Gut 0.60 protein_coding synonymous_variant LOW 129G>A Leu43Leu
M0193464 GLGNFEBA_00210 183108 3 Gut 0.60 protein_coding synonymous_variant LOW 150G>A Lys50Lys
M0193465 GLGNFEBA_00210 183114 3 Gut 0.60 protein_coding synonymous_variant LOW 156A>T Thr52Thr
M0193466 GLGNFEBA_00210 183174 3 Gut 0.60 protein_coding synonymous_variant LOW 216G>A Lys72Lys
M0193467 GLGNFEBA_00210 184110 3 Gut 0.60 protein_coding synonymous_variant LOW 1152G>A Leu384Leu
M0193468 GLGNFEBA_00210 184123 3 Gut 0.60 protein_coding synonymous_variant LOW 1165C>T Leu389Leu
M0193469 GLGNFEBA_00210 184155 3 Gut 0.60 protein_coding synonymous_variant LOW 1197T>C Ala399Ala
M0193470 GLGNFEBA_00210 184168 3 Gut 0.60 protein_coding synonymous_variant LOW 1210C>T Leu404Leu
M0193471 GLGNFEBA_00210 184192 3 Gut 0.60 protein_coding synonymous_variant LOW 1234T>C Leu412Leu
M0193472 GLGNFEBA_00210 184194 3 Gut 0.60 protein_coding synonymous_variant LOW 1236G>A Leu412Leu
M0193473 GLGNFEBA_00210 184197 3 Gut 0.60 protein_coding synonymous_variant LOW 1239A>G Pro413Pro
M0193474 GLGNFEBA_00210 184207 3 Gut 0.60 protein_coding missense_variant MODERATE 1249G>A Val417Ile
M0193475 GLGNFEBA_00210 184212 3 Gut 0.60 protein_coding synonymous_variant LOW 1254C>T Ser418Ser
M0193476 GLGNFEBA_00210 184215 3 Gut 0.60 protein_coding synonymous_variant LOW 1257A>G Val419Val
M0193477 GLGNFEBA_00210 184221 3 Gut 0.60 protein_coding synonymous_variant LOW 1263T>C Asn421Asn
M0193478 GLGNFEBA_00210 184236 3 Gut 0.60 protein_coding synonymous_variant LOW 1278C>T Ser426Ser
M0193479 GLGNFEBA_00210 184254 3 Gut 0.60 protein_coding synonymous_variant LOW 1296T>C Arg432Arg
M0193480 GLGNFEBA_00210 184421 3 Gut 0.60 protein_coding missense_variant MODERATE 1463T>C Val488Ala
M0193481 GLGNFEBA_00210 184479 3 Gut 0.60 protein_coding synonymous_variant LOW 1521T>G Gly507Gly
M0193482 GLGNFEBA_00210 184485 3 Gut 0.60 protein_coding synonymous_variant LOW 1527G>T Thr509Thr
M0193483 GLGNFEBA_00211 184769 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -86A>C None
M0193484 GLGNFEBA_00211 184784 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -71G>A None
M0193485 GLGNFEBA_00211 184942 3 Gut 0.60 protein_coding missense_variant MODERATE 88A>G Lys30Glu
M0193486 GLGNFEBA_00211 185109 3 Gut 0.60 protein_coding synonymous_variant LOW 255G>A Ala85Ala
M0193487 GLGNFEBA_00211 185224 3 Gut 0.60 protein_coding synonymous_variant LOW 370T>C Leu124Leu
M0193488 GLGNFEBA_00211 185328 3 Gut 0.60 protein_coding synonymous_variant LOW 474G>A Gln158Gln
M0193489 GLGNFEBA_00211 185341 3 Gut 0.60 protein_coding synonymous_variant LOW 487A>C Arg163Arg
M0193490 GLGNFEBA_00211 185346 3 Gut 0.60 protein_coding synonymous_variant LOW 492C>T Pro164Pro
M0193491 GLGNFEBA_00211 185352 3 Gut 0.60 protein_coding synonymous_variant LOW 498C>T Phe166Phe
M0193492 GLGNFEBA_00211 185358 3 Gut 0.60 protein_coding synonymous_variant LOW 504A>C Ile168Ile
M0193493 GLGNFEBA_00211 185373 3 Gut 0.60 protein_coding synonymous_variant LOW 519C>T Asp173Asp
M0193494 GLGNFEBA_00211 185380 3 Gut 0.60 protein_coding synonymous_variant LOW 526C>T Leu176Leu
M0193495 GLGNFEBA_00211 185394 3 Gut 0.60 protein_coding synonymous_variant LOW 540A>G Ala180Ala
M0193496 GLGNFEBA_00211 185409 3 Gut 0.60 protein_coding synonymous_variant LOW 555T>C Ser185Ser
M0193497 GLGNFEBA_00211 185476 3 Gut 0.60 protein_coding synonymous_variant LOW 622T>C Leu208Leu
M0193498 GLGNFEBA_00211 185487 3 Gut 0.60 protein_coding synonymous_variant LOW 633T>C Ile211Ile
M0193499 GLGNFEBA_00212 185719 3 Gut 0.60 protein_coding missense_variant MODERATE 73G>A Glu25Lys
M0193500 GLGNFEBA_00212 186186 3 Gut 0.60 protein_coding synonymous_variant LOW 540C>T Arg180Arg
M0193501 GLGNFEBA_00212 186209 3 Gut 0.60 protein_coding missense_variant MODERATE 563A>G Lys188Arg
M0193502 GLGNFEBA_00212 186210 3 Gut 0.60 protein_coding missense_variant MODERATE 564A>T Lys188Asn
M0193503 GLGNFEBA_00212 186222 3 Gut 0.60 protein_coding synonymous_variant LOW 576C>T Asn192Asn
M0193504 GLGNFEBA_00212 186225 3 Gut 0.60 protein_coding synonymous_variant LOW 579C>T Ile193Ile
M0193505 GLGNFEBA_00212 186240 3 Gut 0.60 protein_coding synonymous_variant LOW 594C>T Ile198Ile
M0193506 GLGNFEBA_00212 186714 3 Gut 0.60 protein_coding synonymous_variant LOW 1068C>T Ile356Ile
M0193507 GLGNFEBA_00212 186759 3 Gut 0.60 protein_coding synonymous_variant LOW 1113T>C Gly371Gly
M0193508 GLGNFEBA_00212 186897 3 Gut 0.60 protein_coding stop_gained HIGH 1251T>G Tyr417*
M0193509 GLGNFEBA_00213 186926 3 Gut 0.60 protein_coding missense_variant MODERATE 46A>G Lys16Glu
M0193510 GLGNFEBA_00213 186941 3 Gut 0.60 protein_coding missense_variant MODERATE 61G>A Asp21Asn
M0193511 GLGNFEBA_00213 187010 3 Gut 0.60 protein_coding missense_variant MODERATE 130G>A Ala44Thr
M0193512 GLGNFEBA_00213 187048 3 Gut 0.60 protein_coding synonymous_variant LOW 168T>C Arg56Arg
M0193513 GLGNFEBA_00213 187051 3 Gut 0.60 protein_coding synonymous_variant LOW 171C>T Gly57Gly
M0193514 GLGNFEBA_00213 187114 3 Gut 0.60 protein_coding missense_variant MODERATE 234T>A Asn78Lys
M0193515 GLGNFEBA_00213 187162 3 Gut 0.60 protein_coding synonymous_variant LOW 282A>G Thr94Thr
M0193516 GLGNFEBA_00213 187196 3 Gut 0.60 protein_coding missense_variant MODERATE 316G>A Val106Ile
M0193517 GLGNFEBA_00213 187231 3 Gut 0.60 protein_coding synonymous_variant LOW 351T>C Val117Val
M0193518 GLGNFEBA_00213 187237 3 Gut 0.60 protein_coding synonymous_variant LOW 357C>T Thr119Thr
M0193519 GLGNFEBA_00213 187310 3 Gut 0.60 protein_coding missense_variant MODERATE 430A>G Ile144Val
M0193520 GLGNFEBA_00213 187493 3 Gut 0.60 protein_coding missense_variant MODERATE 613G>A Val205Ile
M0193521 GLGNFEBA_00213 187684 3 Gut 0.60 protein_coding missense_variant MODERATE 804T>G Asp268Glu
M0193522 GLGNFEBA_00213 187744 3 Gut 0.60 protein_coding synonymous_variant LOW 864T>A Ala288Ala
M0193523 GLGNFEBA_00213 187789 3 Gut 0.60 protein_coding synonymous_variant LOW 909A>G Arg303Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
MEMHCBAD_00080 UUY24517.1|GH1 99.8 0 1 451 1 0.9637
GLGNFEBA_00080 UUY24517.1|GH1 99.8 0 1 451 1 0.9637





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
MEMHCBAD_00047 2.A.1.1.74 71 6.4e-171 2 417 0.9928 0.9882 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
MEMHCBAD_00108 2.A.21.3.20 74.7 2.1e-208 1 498 0.9940 0.9960 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.21 The Solute:Sodium Symporter (SSS) Family
GLGNFEBA_00047 2.A.1.1.74 71 6.4e-171 2 417 0.9928 0.9882 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
GLGNFEBA_00108 2.A.21.3.20 74.7 2.1e-208 1 498 0.9940 0.9960 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.21 The Solute:Sodium Symporter (SSS) Family