Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1047
  Reference Plasmid   NZ_CP103101.1
  Reference Plasmid Size   4142
  Reference Plasmid GC Content   0.45
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0194519 EEAOIBFC_00008 4051 10 Gut 0.45 protein_coding upstream_gene_variant MODIFIER -321C>A None
M0194520 EEAOIBFC_00008 4062 14 Gut 0.64 protein_coding upstream_gene_variant MODIFIER -332A>C None
M0194521 EEAOIBFC_00001 30 4 Gut 0.18 protein_coding synonymous_variant LOW 30A>T Arg10Arg
M0194522 EEAOIBFC_00001 150 4 Gut 0.18 protein_coding synonymous_variant LOW 150G>A Glu50Glu
M0194523 EEAOIBFC_00001 231 4 Gut 0.18 protein_coding synonymous_variant LOW 231C>T Asp77Asp
M0194524 EEAOIBFC_00002 434 4 Gut 0.18 protein_coding synonymous_variant LOW 186C>T Ile62Ile
M0194525 EEAOIBFC_00002 488 4 Gut 0.18 protein_coding synonymous_variant LOW 240T>C Tyr80Tyr
M0194526 EEAOIBFC_00004 758 4 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -168A>T None
M0194527 EEAOIBFC_00004 759 4 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -167A>T None
M0194528 EEAOIBFC_00004 816 4 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -110C>T None
M0194529 EEAOIBFC_00004 817 4 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -109A>G None
M0194530 EEAOIBFC_00004 830 4 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -96C>A None
M0194531 EEAOIBFC_00004 837 4 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -89C>T None
M0194532 EEAOIBFC_00005 1693 9 Gut 0.41 protein_coding missense_variant MODERATE 472A>C Lys158Gln
M0194533 EEAOIBFC_00005 1746 4 Gut 0.18 protein_coding synonymous_variant LOW 525C>A Val175Val
M0194534 EEAOIBFC_00005 1990 4 Gut 0.18 protein_coding missense_variant MODERATE 769C>T Pro257Ser
M0194535 EEAOIBFC_00006 2001 4 Gut 0.18 protein_coding missense_variant MODERATE 29C>T Ala10Val
M0194536 EEAOIBFC_00007 2521 4 Gut 0.18 protein_coding synonymous_variant LOW 84C>T Ala28Ala
M0194537 EEAOIBFC_00007 2580 4 Gut 0.18 protein_coding missense_variant MODERATE 143C>T Ala48Val
M0194538 EEAOIBFC_00007 2617 4 Gut 0.18 protein_coding synonymous_variant LOW 180A>G Gln60Gln
M0194539 EEAOIBFC_00007 2619 4 Gut 0.18 protein_coding missense_variant MODERATE 182A>G Gln61Arg
M0194540 EEAOIBFC_00007 2632 4 Gut 0.18 protein_coding synonymous_variant LOW 195A>G Glu65Glu
M0194541 EEAOIBFC_00001 2702 4 Gut 0.18 protein_coding downstream_gene_variant MODIFIER *2450C>T None
M0194542 EEAOIBFC_00008 2706 4 Gut 0.18 protein_coding splice_region_variant&stop_retained_variant LOW 1025A>G Ter342Ter
M0194543 EEAOIBFC_00005 1305 4 Gut 0.18 protein_coding synonymous_variant LOW 84A>T Ala28Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term