Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1052
  Reference Plasmid   NZ_CP103144.1
  Reference Plasmid Size   33024
  Reference Plasmid GC Content   0.47
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0195330 EKKBBOEH_00004 1734 4 Gut 0.67 protein_coding missense_variant MODERATE 761T>C Ile254Thr
M0195331 EKKBBOEH_00002 2513 4 Gut 0.67 protein_coding upstream_gene_variant MODIFIER -1663T>C None
M0195332 EKKBBOEH_00010 12257 5 Gut 0.83 protein_coding upstream_gene_variant MODIFIER -4733A>G None
M0195333 EKKBBOEH_00010 12259 5 Gut 0.83 protein_coding upstream_gene_variant MODIFIER -4735T>A None
M0195334 EKKBBOEH_00010 12260 5 Gut 0.83 protein_coding upstream_gene_variant MODIFIER -4736T>C None
M0195335 EKKBBOEH_00011 12819 5 Gut 0.83 protein_coding upstream_gene_variant MODIFIER -3592T>C None
M0195336 EKKBBOEH_00024 20630 5 Gut 0.83 protein_coding synonymous_variant LOW 150T>A Val50Val
M0195337 EKKBBOEH_00025 21088 5 Gut 0.83 protein_coding missense_variant MODERATE 458G>A Arg153Gln
M0195338 EKKBBOEH_00028 23090 3 Gut 0.50 protein_coding synonymous_variant LOW 81T>C Gly27Gly
M0195339 EKKBBOEH_00028 23246 3 Gut 0.50 protein_coding synonymous_variant LOW 237T>C Gly79Gly
M0195340 EKKBBOEH_00028 23252 4 Gut 0.67 protein_coding missense_variant MODERATE 243A>C Arg81Ser
M0195341 EKKBBOEH_00028 23354 4 Gut 0.67 protein_coding synonymous_variant LOW 345A>G Glu115Glu
M0195342 EKKBBOEH_00028 23381 3 Gut 0.50 protein_coding synonymous_variant LOW 372C>T Cys124Cys
M0195343 EKKBBOEH_00028 23433 3 Gut 0.50 protein_coding synonymous_variant LOW 424T>C Leu142Leu
M0195344 EKKBBOEH_00028 23537 4 Gut 0.67 protein_coding synonymous_variant LOW 528C>A Ile176Ile
M0195345 EKKBBOEH_00028 23546 4 Gut 0.67 protein_coding synonymous_variant LOW 537C>T Val179Val
M0195346 EKKBBOEH_00028 23705 3 Gut 0.50 protein_coding synonymous_variant LOW 696A>C Pro232Pro
M0195347 EKKBBOEH_00031 30997 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4693C>G None
M0195348 EKKBBOEH_00031 30999 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4695C>T None
M0195349 EKKBBOEH_00031 31002 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4698A>T None
M0195350 EKKBBOEH_00031 31009 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4705G>A None
M0195351 EKKBBOEH_00031 31021 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4717C>T None
M0195352 EKKBBOEH_00041 32612 3 Gut 0.50 protein_coding synonymous_variant LOW 165T>C Leu55Leu
M0195353 EKKBBOEH_00023 24143 4 Gut 0.67 protein_coding upstream_gene_variant MODIFIER -4895A>T None
M0195354 EKKBBOEH_00023 24144 4 Gut 0.67 protein_coding upstream_gene_variant MODIFIER -4896T>A None
M0195355 EKKBBOEH_00023 24145 4 Gut 0.67 protein_coding upstream_gene_variant MODIFIER -4897A>T None
M0195356 EKKBBOEH_00030 24358 3 Gut 0.50 protein_coding missense_variant MODERATE 983A>C Gln328Pro
M0195357 EKKBBOEH_00030 24359 3 Gut 0.50 protein_coding missense_variant MODERATE 982C>G Gln328Glu
M0195358 EKKBBOEH_00030 24361 3 Gut 0.50 protein_coding missense_variant MODERATE 980A>T Glu327Val
M0195359 EKKBBOEH_00024 19282 3 Gut 0.50 protein_coding synonymous_variant LOW 1498T>C Leu500Leu
M0195360 EKKBBOEH_00024 19283 3 Gut 0.50 protein_coding synonymous_variant LOW 1497A>G Ser499Ser
M0195361 EKKBBOEH_00024 19286 3 Gut 0.50 protein_coding synonymous_variant LOW 1494A>C Ala498Ala
M0195362 EKKBBOEH_00024 19289 3 Gut 0.50 protein_coding synonymous_variant LOW 1491C>A Ile497Ile
M0195363 EKKBBOEH_00024 19292 3 Gut 0.50 protein_coding synonymous_variant LOW 1488A>G Val496Val
M0195364 EKKBBOEH_00024 19298 3 Gut 0.50 protein_coding synonymous_variant LOW 1482G>C Thr494Thr
M0195365 EKKBBOEH_00024 19300 3 Gut 0.50 protein_coding missense_variant MODERATE 1480A>G Thr494Ala
M0195366 EKKBBOEH_00024 19304 3 Gut 0.50 protein_coding synonymous_variant LOW 1476G>A Glu492Glu
M0195367 EKKBBOEH_00024 19307 3 Gut 0.50 protein_coding synonymous_variant LOW 1473G>C Ser491Ser
M0195368 EKKBBOEH_00024 19685 3 Gut 0.50 protein_coding synonymous_variant LOW 1095G>A Pro365Pro
M0195369 EKKBBOEH_00024 19738 3 Gut 0.50 protein_coding missense_variant MODERATE 1042G>T Ala348Ser
M0195370 EKKBBOEH_00024 20042 3 Gut 0.50 protein_coding synonymous_variant LOW 738G>A Glu246Glu
M0195371 EKKBBOEH_00024 20299 3 Gut 0.50 protein_coding missense_variant MODERATE 481A>G Thr161Ala
M0195372 EKKBBOEH_00024 20441 3 Gut 0.50 protein_coding synonymous_variant LOW 339A>G Lys113Lys
M0195373 EKKBBOEH_00024 20456 3 Gut 0.50 protein_coding synonymous_variant LOW 324A>G Val108Val
M0195374 EKKBBOEH_00024 20491 3 Gut 0.50 protein_coding synonymous_variant LOW 289T>C Leu97Leu
M0195375 EKKBBOEH_00019 20831 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4701C>T None
M0195376 EKKBBOEH_00019 20836 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4706G>A None
M0195377 EKKBBOEH_00019 20860 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4730A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term