Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1057
  Reference Plasmid   NZ_CP103186.1
  Reference Plasmid Size   7408
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0195384 EPDHABIN_00001 117 3 Gut 0.21 protein_coding synonymous_variant LOW 117G>A Glu39Glu
M0195385 EPDHABIN_00001 135 3 Gut 0.21 protein_coding synonymous_variant LOW 135C>T Asn45Asn
M0195386 EPDHABIN_00001 157 3 Gut 0.21 protein_coding missense_variant MODERATE 157T>G Ser53Ala
M0195387 EPDHABIN_00002 1016 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -37C>T None
M0195388 EPDHABIN_00003 2284 3 Gut 0.21 protein_coding missense_variant MODERATE 184A>T Ser62Cys
M0195389 EPDHABIN_00003 2305 4 Gut 0.29 protein_coding missense_variant MODERATE 205G>A Glu69Lys
M0195390 EPDHABIN_00005 3141 3 Gut 0.21 protein_coding missense_variant MODERATE 334G>A Glu112Lys
M0195391 EPDHABIN_00005 3215 3 Gut 0.21 protein_coding missense_variant MODERATE 260G>C Gly87Ala
M0195392 EPDHABIN_00005 3218 3 Gut 0.21 protein_coding missense_variant MODERATE 257G>C Gly86Ala
M0195393 EPDHABIN_00005 3888 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -414C>T None
M0195394 EPDHABIN_00005 4064 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -590T>A None
M0195395 EPDHABIN_00005 4076 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -602A>G None
M0195396 EPDHABIN_00005 5327 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -1853T>C None
M0195397 EPDHABIN_00005 5533 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -2059C>T None
M0195398 EPDHABIN_00005 5536 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -2062C>T None
M0195399 EPDHABIN_00005 6611 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -3137A>C None
M0195400 EPDHABIN_00005 6654 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -3180G>A None
M0195401 EPDHABIN_00005 6658 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -3184C>T None
M0195402 EPDHABIN_00005 6704 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -3230G>A None
M0195403 EPDHABIN_00005 6705 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -3231C>T None
M0195404 EPDHABIN_00005 6741 4 Gut 0.29 protein_coding upstream_gene_variant MODIFIER -3267C>T None
M0195405 EPDHABIN_00005 6785 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -3311A>G None
M0195406 EPDHABIN_00005 6798 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -3324T>G None
M0195407 EPDHABIN_00005 6824 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -3350A>G None
M0195408 EPDHABIN_00005 6965 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -3491A>G None
M0195409 EPDHABIN_00005 7025 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -3551C>T None
M0195410 EPDHABIN_00005 7097 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -3623A>G None
M0195411 EPDHABIN_00005 7162 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -3688C>T None
M0195412 EPDHABIN_00005 7209 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -3735T>C None
M0195413 EPDHABIN_00005 7379 3 Gut 0.21 protein_coding upstream_gene_variant MODIFIER -3905G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term