Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1059
  Reference Plasmid   NZ_CP103212.1
  Reference Plasmid Size   10051
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0195437 OABIONKC_00014 7268 11 Gut 0.50 protein_coding missense_variant MODERATE 832A>G Ile278Val
M0195438 OABIONKC_00014 7359 10 Gut 0.45 protein_coding synonymous_variant LOW 741G>A Gln247Gln
M0195439 OABIONKC_00014 7452 11 Gut 0.50 protein_coding synonymous_variant LOW 648C>T Val216Val
M0195440 OABIONKC_00014 7536 11 Gut 0.50 protein_coding synonymous_variant LOW 564G>A Lys188Lys
M0195441 OABIONKC_00014 7590 11 Gut 0.50 protein_coding synonymous_variant LOW 510T>C Phe170Phe
M0195442 OABIONKC_00014 7601 11 Gut 0.50 protein_coding missense_variant MODERATE 499A>C Lys167Gln
M0195443 OABIONKC_00014 7734 11 Gut 0.50 protein_coding synonymous_variant LOW 366T>C Phe122Phe
M0195444 OABIONKC_00014 7950 11 Gut 0.50 protein_coding synonymous_variant LOW 150C>T His50His
M0195445 OABIONKC_00014 8058 12 Gut 0.55 protein_coding synonymous_variant LOW 42C>T Tyr14Tyr
M0195446 OABIONKC_00014 8067 13 Gut 0.59 protein_coding synonymous_variant LOW 33T>C Phe11Phe
M0195447 OABIONKC_00014 8072 14 Gut 0.64 protein_coding missense_variant MODERATE 28A>G Ile10Val
M0195448 OABIONKC_00015 8193 11 Gut 0.50 protein_coding missense_variant MODERATE 370A>G Asn124Asp
M0195449 OABIONKC_00015 8214 11 Gut 0.50 protein_coding missense_variant MODERATE 349A>G Asn117Asp
M0195450 OABIONKC_00015 8245 11 Gut 0.50 protein_coding synonymous_variant LOW 318C>A Gly106Gly
M0195451 OABIONKC_00015 8248 11 Gut 0.50 protein_coding synonymous_variant LOW 315C>T His105His
M0195452 OABIONKC_00015 8254 11 Gut 0.50 protein_coding synonymous_variant LOW 309T>C Tyr103Tyr
M0195453 OABIONKC_00015 8269 11 Gut 0.50 protein_coding synonymous_variant LOW 294C>T Cys98Cys
M0195454 OABIONKC_00015 8299 11 Gut 0.50 protein_coding synonymous_variant LOW 264C>T Asn88Asn
M0195455 OABIONKC_00015 8302 11 Gut 0.50 protein_coding synonymous_variant LOW 261G>A Val87Val
M0195456 OABIONKC_00015 8335 11 Gut 0.50 protein_coding synonymous_variant LOW 228C>T Phe76Phe
M0195457 OABIONKC_00015 8347 11 Gut 0.50 protein_coding synonymous_variant LOW 216T>C Ala72Ala
M0195458 OABIONKC_00015 8356 11 Gut 0.50 protein_coding synonymous_variant LOW 207C>A Leu69Leu
M0195459 OABIONKC_00015 8425 11 Gut 0.50 protein_coding synonymous_variant LOW 138C>T Asn46Asn
M0195460 OABIONKC_00015 8431 11 Gut 0.50 protein_coding synonymous_variant LOW 132G>A Glu44Glu
M0195461 OABIONKC_00015 8446 11 Gut 0.50 protein_coding synonymous_variant LOW 117T>C Asp39Asp
M0195462 OABIONKC_00015 8497 11 Gut 0.50 protein_coding synonymous_variant LOW 66A>T Thr22Thr
M0195463 OABIONKC_00015 8540 11 Gut 0.50 protein_coding missense_variant MODERATE 23A>G Tyr8Cys
M0195464 OABIONKC_00011 8565 12 Gut 0.55 protein_coding upstream_gene_variant MODIFIER -2442C>T None
M0195465 OABIONKC_00011 8566 11 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -2443T>C None
M0195466 OABIONKC_00011 8589 13 Gut 0.59 protein_coding upstream_gene_variant MODIFIER -2466G>A None
M0195467 OABIONKC_00011 8632 10 Gut 0.45 protein_coding upstream_gene_variant MODIFIER -2509C>A None
M0195468 OABIONKC_00011 8726 11 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -2603C>T None
M0195469 OABIONKC_00011 8750 13 Gut 0.59 protein_coding upstream_gene_variant MODIFIER -2627A>G None
M0195470 OABIONKC_00011 8770 11 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -2647A>G None
M0195471 OABIONKC_00011 8774 13 Gut 0.59 protein_coding upstream_gene_variant MODIFIER -2651C>T None
M0195472 OABIONKC_00011 8864 9 Gut 0.41 protein_coding upstream_gene_variant MODIFIER -2741T>C None
M0195473 OABIONKC_00011 8887 12 Gut 0.55 protein_coding upstream_gene_variant MODIFIER -2764C>T None
M0195474 OABIONKC_00016 9038 11 Gut 0.50 protein_coding synonymous_variant LOW 109T>C Leu37Leu
M0195475 OABIONKC_00016 9148 10 Gut 0.45 protein_coding synonymous_variant LOW 219T>C Phe73Phe
M0195476 OABIONKC_00017 9179 11 Gut 0.50 protein_coding synonymous_variant LOW 27A>G Pro9Pro
M0195477 OABIONKC_00017 9335 10 Gut 0.45 protein_coding synonymous_variant LOW 183A>G Gly61Gly
M0195478 OABIONKC_00014 7833 3 Gut 0.14 protein_coding synonymous_variant LOW 267A>G Leu89Leu
M0195479 OABIONKC_00008 3856 6 Gut 0.27 protein_coding missense_variant MODERATE 4A>G Lys2Glu
M0195480 OABIONKC_00008 3947 6 Gut 0.27 protein_coding missense_variant MODERATE 95T>C Ile32Thr
M0195481 OABIONKC_00008 3954 5 Gut 0.23 protein_coding synonymous_variant LOW 102G>A Glu34Glu
M0195482 OABIONKC_00009 4280 5 Gut 0.23 protein_coding missense_variant MODERATE 132T>G Asp44Glu
M0195483 OABIONKC_00009 4625 5 Gut 0.23 protein_coding synonymous_variant LOW 477T>C Asp159Asp
M0195484 OABIONKC_00009 4850 4 Gut 0.18 protein_coding synonymous_variant LOW 702T>C His234His
M0195485 OABIONKC_00010 4950 3 Gut 0.14 protein_coding synonymous_variant LOW 51G>A Gly17Gly
M0195486 OABIONKC_00011 8848 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -2725A>G None
M0195487 OABIONKC_00011 8831 8 Gut 0.36 protein_coding upstream_gene_variant MODIFIER -2708C>A None
M0195488 OABIONKC_00017 9419 3 Gut 0.14 protein_coding synonymous_variant LOW 267C>T Val89Val
M0195489 OABIONKC_00011 9537 9 Gut 0.41 protein_coding upstream_gene_variant MODIFIER -3414C>T None
M0195490 OABIONKC_00004 3840 4 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -1324A>G None
M0195491 OABIONKC_00008 3873 5 Gut 0.23 protein_coding synonymous_variant LOW 21G>A Glu7Glu
M0195492 OABIONKC_00008 4125 3 Gut 0.14 protein_coding missense_variant MODERATE 273T>A Asn91Lys
M0195493 OABIONKC_00009 4238 3 Gut 0.14 protein_coding synonymous_variant LOW 90C>T Thr30Thr
M0195494 OABIONKC_00009 4256 3 Gut 0.14 protein_coding synonymous_variant LOW 108G>A Glu36Glu
M0195495 OABIONKC_00009 4262 3 Gut 0.14 protein_coding synonymous_variant LOW 114C>T Phe38Phe
M0195496 OABIONKC_00009 4292 3 Gut 0.14 protein_coding synonymous_variant LOW 144G>A Glu48Glu
M0195497 OABIONKC_00009 4307 3 Gut 0.14 protein_coding synonymous_variant LOW 159T>C Phe53Phe
M0195498 OABIONKC_00009 4355 4 Gut 0.18 protein_coding synonymous_variant LOW 207C>T Ser69Ser
M0195499 OABIONKC_00009 4386 3 Gut 0.14 protein_coding missense_variant MODERATE 238G>A Asp80Asn
M0195500 OABIONKC_00009 4409 4 Gut 0.18 protein_coding synonymous_variant LOW 261T>C Gly87Gly
M0195501 OABIONKC_00009 4412 4 Gut 0.18 protein_coding synonymous_variant LOW 264T>C Asn88Asn
M0195502 OABIONKC_00009 4433 4 Gut 0.18 protein_coding synonymous_variant LOW 285T>C Gly95Gly
M0195503 OABIONKC_00009 4451 4 Gut 0.18 protein_coding synonymous_variant LOW 303C>T Tyr101Tyr
M0195504 OABIONKC_00009 4469 3 Gut 0.14 protein_coding synonymous_variant LOW 321C>T Ser107Ser
M0195505 OABIONKC_00009 4541 4 Gut 0.18 protein_coding synonymous_variant LOW 393A>C Leu131Leu
M0195506 OABIONKC_00009 4545 4 Gut 0.18 protein_coding missense_variant MODERATE 397C>A Gln133Lys
M0195507 OABIONKC_00009 4547 4 Gut 0.18 protein_coding synonymous_variant LOW 399G>A Gln133Gln
M0195508 OABIONKC_00009 4550 4 Gut 0.18 protein_coding synonymous_variant LOW 402T>C Asp134Asp
M0195509 OABIONKC_00009 4571 4 Gut 0.18 protein_coding synonymous_variant LOW 423T>A Ala141Ala
M0195510 OABIONKC_00009 4580 4 Gut 0.18 protein_coding synonymous_variant LOW 432T>C Ala144Ala
M0195511 OABIONKC_00009 4601 3 Gut 0.14 protein_coding synonymous_variant LOW 453A>G Glu151Glu
M0195512 OABIONKC_00009 4667 3 Gut 0.14 protein_coding synonymous_variant LOW 519T>C Asp173Asp
M0195513 OABIONKC_00009 4669 3 Gut 0.14 protein_coding missense_variant MODERATE 521A>G Asp174Gly
M0195514 OABIONKC_00009 4673 3 Gut 0.14 protein_coding synonymous_variant LOW 525T>C Val175Val
M0195515 OABIONKC_00009 4677 3 Gut 0.14 protein_coding missense_variant MODERATE 529A>G Ile177Val
M0195516 OABIONKC_00009 4678 3 Gut 0.14 protein_coding missense_variant MODERATE 530T>C Ile177Thr
M0195517 OABIONKC_00009 4680 3 Gut 0.14 protein_coding synonymous_variant LOW 532C>A Arg178Arg
M0195518 OABIONKC_00009 4691 3 Gut 0.14 protein_coding synonymous_variant LOW 543G>A Gly181Gly
M0195519 OABIONKC_00009 4715 3 Gut 0.14 protein_coding synonymous_variant LOW 567G>T Arg189Arg
M0195520 OABIONKC_00009 4727 3 Gut 0.14 protein_coding synonymous_variant LOW 579A>G Lys193Lys
M0195521 OABIONKC_00009 4733 3 Gut 0.14 protein_coding synonymous_variant LOW 585C>T Gly195Gly
M0195522 OABIONKC_00009 4763 3 Gut 0.14 protein_coding synonymous_variant LOW 615A>C Thr205Thr
M0195523 OABIONKC_00009 4778 3 Gut 0.14 protein_coding synonymous_variant LOW 630C>T Gly210Gly
M0195524 OABIONKC_00009 4781 3 Gut 0.14 protein_coding synonymous_variant LOW 633C>T Tyr211Tyr
M0195525 OABIONKC_00009 4788 3 Gut 0.14 protein_coding missense_variant MODERATE 640A>G Lys214Glu
M0195526 OABIONKC_00009 4805 3 Gut 0.14 protein_coding synonymous_variant LOW 657G>A Thr219Thr
M0195527 OABIONKC_00009 4834 3 Gut 0.14 protein_coding missense_variant MODERATE 686G>A Gly229Asp
M0195528 OABIONKC_00009 4835 3 Gut 0.14 protein_coding synonymous_variant LOW 687C>T Gly229Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term