Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1078
  Reference Plasmid   NZ_CP104486.1
  Reference Plasmid Size   69202
  Reference Plasmid GC Content   0.52
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0195645 BALGGKEA_00012 12743 3 Gut 1.00 protein_coding synonymous_variant LOW 243T>A Ala81Ala
M0195646 BALGGKEA_00012 12746 3 Gut 1.00 protein_coding synonymous_variant LOW 240C>T Phe80Phe
M0195647 BALGGKEA_00012 12752 3 Gut 1.00 protein_coding synonymous_variant LOW 234A>G Glu78Glu
M0195648 BALGGKEA_00012 12821 3 Gut 1.00 protein_coding synonymous_variant LOW 165C>T Asn55Asn
M0195649 BALGGKEA_00012 12825 3 Gut 1.00 protein_coding missense_variant MODERATE 161A>G His54Arg
M0195650 BALGGKEA_00012 12851 3 Gut 1.00 protein_coding synonymous_variant LOW 135T>C Arg45Arg
M0195651 BALGGKEA_00012 12868 3 Gut 1.00 protein_coding missense_variant MODERATE 118C>T Arg40Cys
M0195652 BALGGKEA_00012 12887 3 Gut 1.00 protein_coding synonymous_variant LOW 99T>C Asp33Asp
M0195653 BALGGKEA_00012 12911 3 Gut 1.00 protein_coding synonymous_variant LOW 75C>T Pro25Pro
M0195654 BALGGKEA_00012 12913 3 Gut 1.00 protein_coding missense_variant MODERATE 73C>G Pro25Ala
M0195655 BALGGKEA_00012 12914 3 Gut 1.00 protein_coding synonymous_variant LOW 72C>T Asn24Asn
M0195656 BALGGKEA_00012 12923 3 Gut 1.00 protein_coding synonymous_variant LOW 63T>C Ser21Ser
M0195657 BALGGKEA_00012 12929 3 Gut 1.00 protein_coding synonymous_variant LOW 57T>C Ala19Ala
M0195658 BALGGKEA_00012 12977 3 Gut 1.00 protein_coding synonymous_variant LOW 9C>T Gly3Gly
M0195659 BALGGKEA_00011 12988 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -911G>A None
M0195660 BALGGKEA_00011 12999 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -922C>T None
M0195661 BALGGKEA_00011 13014 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -937T>C None
M0195662 BALGGKEA_00011 13037 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -960T>C None
M0195663 BALGGKEA_00011 13057 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -980G>A None
M0195664 BALGGKEA_00011 13058 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -981T>G None
M0195665 BALGGKEA_00011 13079 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -1002T>C None
M0195666 BALGGKEA_00011 13084 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -1007G>C None
M0195667 BALGGKEA_00011 13088 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -1011A>C None
M0195668 BALGGKEA_00011 13089 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -1012C>T None
M0195669 BALGGKEA_00011 13131 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -1054T>C None
M0195670 BALGGKEA_00013 13160 3 Gut 1.00 protein_coding synonymous_variant LOW 351T>C Asn117Asn
M0195671 BALGGKEA_00013 13190 3 Gut 1.00 protein_coding synonymous_variant LOW 321G>A Glu107Glu
M0195672 BALGGKEA_00013 13208 3 Gut 1.00 protein_coding missense_variant MODERATE 303G>T Glu101Asp
M0195673 BALGGKEA_00013 13216 3 Gut 1.00 protein_coding missense_variant MODERATE 295G>C Glu99Gln
M0195674 BALGGKEA_00013 13223 3 Gut 1.00 protein_coding synonymous_variant LOW 288C>T Ser96Ser
M0195675 BALGGKEA_00013 13237 3 Gut 1.00 protein_coding missense_variant MODERATE 274A>T Ile92Leu
M0195676 BALGGKEA_00013 13244 3 Gut 1.00 protein_coding synonymous_variant LOW 267T>C Asn89Asn
M0195677 BALGGKEA_00013 13325 3 Gut 1.00 protein_coding synonymous_variant LOW 186G>A Glu62Glu
M0195678 BALGGKEA_00013 13345 3 Gut 1.00 protein_coding missense_variant MODERATE 166A>G Thr56Ala
M0195679 BALGGKEA_00013 13348 3 Gut 1.00 protein_coding synonymous_variant LOW 163C>A Arg55Arg
M0195680 BALGGKEA_00013 13385 3 Gut 1.00 protein_coding synonymous_variant LOW 126G>A Ala42Ala
M0195681 BALGGKEA_00013 13388 3 Gut 1.00 protein_coding synonymous_variant LOW 123C>T Ala41Ala
M0195682 BALGGKEA_00013 13406 3 Gut 1.00 protein_coding synonymous_variant LOW 105A>C Arg35Arg
M0195683 BALGGKEA_00013 13478 3 Gut 1.00 protein_coding synonymous_variant LOW 33A>G Lys11Lys
M0195684 BALGGKEA_00013 13481 3 Gut 1.00 protein_coding synonymous_variant LOW 30C>T Phe10Phe
M0195685 BALGGKEA_00014 13939 3 Gut 1.00 protein_coding synonymous_variant LOW 534C>T Ile178Ile
M0195686 BALGGKEA_00014 14107 3 Gut 1.00 protein_coding synonymous_variant LOW 366G>A Lys122Lys
M0195687 BALGGKEA_00014 14113 3 Gut 1.00 protein_coding synonymous_variant LOW 360A>G Glu120Glu
M0195688 BALGGKEA_00014 14218 3 Gut 1.00 protein_coding synonymous_variant LOW 255T>C Ala85Ala
M0195689 BALGGKEA_00014 14287 3 Gut 1.00 protein_coding synonymous_variant LOW 186G>A Pro62Pro
M0195690 BALGGKEA_00011 14539 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2462T>C None
M0195691 BALGGKEA_00011 14540 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2463A>G None
M0195692 BALGGKEA_00011 14564 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2487G>A None
M0195693 BALGGKEA_00011 14580 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2503T>C None
M0195694 BALGGKEA_00011 14603 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2526C>T None
M0195695 BALGGKEA_00011 14609 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2532A>C None
M0195696 BALGGKEA_00011 14620 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2543A>C None
M0195697 BALGGKEA_00011 14622 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2545T>C None
M0195698 BALGGKEA_00011 14623 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2546A>G None
M0195699 BALGGKEA_00011 14641 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2564A>G None
M0195700 BALGGKEA_00011 14661 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2584G>A None
M0195701 BALGGKEA_00011 14663 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2586C>A None
M0195702 BALGGKEA_00011 14667 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2590G>A None
M0195703 BALGGKEA_00011 14698 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2621C>T None
M0195704 BALGGKEA_00011 14702 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2625A>C None
M0195705 BALGGKEA_00011 14703 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2626T>C None
M0195706 BALGGKEA_00011 14746 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2669T>C None
M0195707 BALGGKEA_00011 14769 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2692G>T None
M0195708 BALGGKEA_00011 14797 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2720G>T None
M0195709 BALGGKEA_00011 14844 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2767C>T None
M0195710 BALGGKEA_00011 14869 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2792A>T None
M0195711 BALGGKEA_00011 14883 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2806C>T None
M0195712 BALGGKEA_00011 14920 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2843T>A None
M0195713 BALGGKEA_00011 14990 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -2913C>T None
M0195714 BALGGKEA_00015 15013 3 Gut 1.00 protein_coding missense_variant MODERATE 16A>T Ser6Cys
M0195715 BALGGKEA_00015 15014 3 Gut 1.00 protein_coding missense_variant MODERATE 17G>C Ser6Thr
M0195716 BALGGKEA_00015 15015 3 Gut 1.00 protein_coding missense_variant MODERATE 18T>G Ser6Arg
M0195717 BALGGKEA_00015 15018 3 Gut 1.00 protein_coding synonymous_variant LOW 21C>T Asn7Asn
M0195718 BALGGKEA_00015 15046 3 Gut 1.00 protein_coding missense_variant MODERATE 49A>C Lys17Gln
M0195719 BALGGKEA_00015 15051 3 Gut 1.00 protein_coding synonymous_variant LOW 54T>C Ile18Ile
M0195720 BALGGKEA_00015 15078 3 Gut 1.00 protein_coding synonymous_variant LOW 81T>C Gly27Gly
M0195721 BALGGKEA_00015 15157 3 Gut 1.00 protein_coding missense_variant MODERATE 160A>G Ile54Val
M0195722 BALGGKEA_00015 15160 3 Gut 1.00 protein_coding missense_variant MODERATE 163G>A Ala55Thr
M0195723 BALGGKEA_00015 15191 3 Gut 1.00 protein_coding missense_variant MODERATE 194G>T Gly65Val
M0195724 BALGGKEA_00015 15223 3 Gut 1.00 protein_coding missense_variant MODERATE 226C>T Pro76Ser
M0195725 BALGGKEA_00015 15444 3 Gut 1.00 protein_coding synonymous_variant LOW 447A>G Val149Val
M0195726 BALGGKEA_00015 15471 3 Gut 1.00 protein_coding synonymous_variant LOW 474A>C Val158Val
M0195727 BALGGKEA_00015 15624 3 Gut 1.00 protein_coding synonymous_variant LOW 627G>A Gly209Gly
M0195728 BALGGKEA_00015 15651 3 Gut 1.00 protein_coding synonymous_variant LOW 654G>A Gly218Gly
M0195729 BALGGKEA_00015 15654 3 Gut 1.00 protein_coding missense_variant MODERATE 657A>C Glu219Asp
M0195730 BALGGKEA_00015 15669 3 Gut 1.00 protein_coding synonymous_variant LOW 672A>G Val224Val
M0195731 BALGGKEA_00015 15696 3 Gut 1.00 protein_coding synonymous_variant LOW 699G>A Pro233Pro
M0195732 BALGGKEA_00015 15709 3 Gut 1.00 protein_coding missense_variant MODERATE 712G>A Val238Ile
M0195733 BALGGKEA_00015 15716 3 Gut 1.00 protein_coding missense_variant MODERATE 719A>C Glu240Ala
M0195734 BALGGKEA_00015 15762 3 Gut 1.00 protein_coding synonymous_variant LOW 765A>G Glu255Glu
M0195735 BALGGKEA_00015 15790 3 Gut 1.00 protein_coding synonymous_variant LOW 793T>C Leu265Leu
M0195736 BALGGKEA_00015 15791 3 Gut 1.00 protein_coding missense_variant MODERATE 794T>G Leu265Trp
M0195737 BALGGKEA_00015 15792 3 Gut 1.00 protein_coding synonymous_variant LOW 795G>A Leu265Leu
M0195738 BALGGKEA_00015 15801 3 Gut 1.00 protein_coding synonymous_variant LOW 804C>T Arg268Arg
M0195739 BALGGKEA_00015 15812 3 Gut 1.00 protein_coding missense_variant MODERATE 815T>C Val272Ala
M0195740 BALGGKEA_00015 15903 3 Gut 1.00 protein_coding missense_variant MODERATE 906G>T Lys302Asn
M0195741 BALGGKEA_00011 16070 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -3993T>C None
M0195742 BALGGKEA_00011 16097 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4020T>C None
M0195743 BALGGKEA_00011 16163 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4086C>T None
M0195744 BALGGKEA_00011 16177 3 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4100G>T None
M0195745 BALGGKEA_00016 16339 3 Gut 1.00 protein_coding synonymous_variant LOW 33A>G Arg11Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
BALGGKEA_00006 PHI:5228 BAHT 91.1 2.5e-234 39 444 0.9144 0.9927 rodents None heptosyltransferase reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
BALGGKEA_00006 QCT87625.1|GT112 92.1 1.06e-295 39 444 0.9144 0.9927
BALGGKEA_00035 UMU70165.1|GH23 99.1 7.84e-155 1 215 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
BALGGKEA_00077 1.E.53.1.11 98.5 3.2e-32 1 68 1.0000 1.0000 1 Channels/Pores 1.E Holins 1.E.53 The Toxic Hok/Gef Protein (Hok/Gef) Family