Cluster Information | Plasmid Cluster ID | C1080 |
Reference Plasmid | NZ_CP104587.1 | |
Reference Plasmid Size | 426499 | |
Reference Plasmid GC Content | 0.57 | |
Reference Plasmid Mobility Type | non-mobilizable |
mutid | gname | pos | count | tissue | frequnt | biotype | consequence | impact | nucchange | aachange |
---|---|---|---|---|---|---|---|---|---|---|
M0106984 | HPPNAFDN_00478 | 385490 | 5 | Skin | 0.25 | protein_coding | missense_variant | MODERATE | 257T>A | Val86Glu |
M0106985 | HPPNAFDN_00478 | 385505 | 5 | Skin | 0.25 | protein_coding | missense_variant | MODERATE | 242C>T | Ala81Val |
M0106986 | HPPNAFDN_00474 | 386435 | 5 | Skin | 0.25 | protein_coding | upstream_gene_variant | MODIFIER | -3327C>T | None |
M0106987 | HPPNAFDN_00484 | 388939 | 5 | Skin | 0.25 | protein_coding | synonymous_variant | LOW | 1026T>C | Tyr342Tyr |
M0106988 | HPPNAFDN_00401 | 315957 | 6 | Skin | 0.30 | protein_coding | synonymous_variant | LOW | 822A>G | Val274Val |
M0106989 | HPPNAFDN_00401 | 316238 | 6 | Skin | 0.30 | protein_coding | missense_variant | MODERATE | 1103A>G | Glu368Gly |
M0106990 | HPPNAFDN_00401 | 316257 | 6 | Skin | 0.30 | protein_coding | synonymous_variant | LOW | 1122A>G | Gln374Gln |
M0106991 | HPPNAFDN_00401 | 316312 | 6 | Skin | 0.30 | protein_coding | missense_variant | MODERATE | 1177C>T | Pro393Ser |
M0106992 | HPPNAFDN_00401 | 316586 | 6 | Skin | 0.30 | protein_coding | missense_variant | MODERATE | 1451A>G | His484Arg |
M0106993 | HPPNAFDN_00401 | 316591 | 6 | Skin | 0.30 | protein_coding | missense_variant | MODERATE | 1456C>T | Pro486Ser |
M0106994 | HPPNAFDN_00401 | 316594 | 6 | Skin | 0.30 | protein_coding | missense_variant | MODERATE | 1459G>T | Ala487Ser |
M0106995 | HPPNAFDN_00484 | 388022 | 3 | Skin | 0.15 | protein_coding | missense_variant | MODERATE | 109A>G | Thr37Ala |
M0106996 | HPPNAFDN_00401 | 315790 | 3 | Skin | 0.15 | protein_coding | missense_variant | MODERATE | 655A>G | Ser219Gly |
M0106997 | HPPNAFDN_00401 | 315817 | 3 | Skin | 0.15 | protein_coding | synonymous_variant | LOW | 682C>T | Leu228Leu |
M0106998 | HPPNAFDN_00401 | 315835 | 3 | Skin | 0.15 | protein_coding | synonymous_variant | LOW | 700C>T | Leu234Leu |
M0106999 | HPPNAFDN_00401 | 315837 | 3 | Skin | 0.15 | protein_coding | synonymous_variant | LOW | 702G>C | Leu234Leu |
M0107000 | HPPNAFDN_00401 | 315840 | 3 | Skin | 0.15 | protein_coding | missense_variant | MODERATE | 705C>A | Asp235Glu |
M0107001 | HPPNAFDN_00401 | 315870 | 3 | Skin | 0.15 | protein_coding | synonymous_variant | LOW | 735C>T | Arg245Arg |
M0107002 | HPPNAFDN_00401 | 315871 | 3 | Skin | 0.15 | protein_coding | synonymous_variant | LOW | 736T>C | Leu246Leu |
M0107003 | HPPNAFDN_00401 | 315888 | 3 | Skin | 0.15 | protein_coding | synonymous_variant | LOW | 753A>G | Glu251Glu |
Gene Name | vf_gene_id | vf_name | identity | evalue | qstart | qend | query_coverage | subject_coverage | vf_category | gene_description | condition |
---|
Gene Name | compound | identity | evalue | qstart | qend | query_coverage | subject_coverage | group |
---|---|---|---|---|---|---|---|---|
HPPNAFDN_00349 | Tellurium (Te) | 71.3 | 2.9e-138 | 1 | 340 | 0.9942 | 0.9884 | experiment |
HPPNAFDN_00350 | Tellurium (Te) | 70.3 | 3.6e-77 | 1 | 192 | 1.0000 | 1.0000 | experiment |
HPPNAFDN_00351 | Tellurium (Te) | 70.7 | 5.6e-78 | 1 | 191 | 0.9948 | 1.0000 | experiment |
HPPNAFDN_00406 | Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Chlorhexidine [class: Biguanides], Pyronin Y [class: Xanthene], Rhodamine 6G [class: Xanthene], Methyl Viologen [class: Paraquat], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamindine], Acridine Orange [class: Acridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Deoxycholate (SDC) [class: Acid], Crystal Violet [class: Triarylmethane], Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)], Cetylpyridinium Chloride (CPC) [class: Quaternary Ammonium Compounds (QACs)], Dequalinium [class: Quaternary Ammonium Compounds (QACs)] | 100 | 1.1e-60 | 1 | 115 | 1.0000 | 1.0000 | experiment |
HPPNAFDN_00407 | Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)] | 93.6 | 4.2e-54 | 1 | 110 | 1.0000 | 1.0000 | experiment |
HPPNAFDN_00453 | Mercury (Hg) | 75.2 | 8.5e-236 | 5 | 564 | 0.9947 | 1.0000 | experiment |
HPPNAFDN_00454 | Mercury (Hg) | 71.7 | 1e-55 | 6 | 143 | 0.9583 | 0.9787 | experiment |
HPPNAFDN_00455 | Mercury (Hg) | 76.9 | 8.9e-34 | 1 | 91 | 1.0000 | 1.0000 | experiment |
HPPNAFDN_00456 | Mercury (Hg) | 83.6 | 7e-52 | 1 | 116 | 1.0000 | 1.0000 | experiment |
HPPNAFDN_00457 | Mercury (Hg) | 77.9 | 3.2e-56 | 1 | 136 | 1.0000 | 0.9444 | experiment |
HPPNAFDN_00349 | Tellurium (Te) | 72.2 | 5e-139 | 1 | 340 | 0.9942 | 0.9884 | prediction |
HPPNAFDN_00350 | Tellurium (Te) | 72.4 | 1e-77 | 1 | 192 | 1.0000 | 1.0000 | prediction |
HPPNAFDN_00351 | Tellurium (Te) | 71.2 | 5.7e-76 | 1 | 191 | 0.9948 | 1.0000 | prediction |
HPPNAFDN_00407 | Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)] | 100 | 1.7e-53 | 1 | 110 | 1.0000 | 1.0000 | prediction |
HPPNAFDN_00453 | Mercury (Hg), Phenylmercury Acetate [class: Organo-mercury] | 100 | 3.60000000001819e-313 | 5 | 564 | 0.9929 | 1.0000 | prediction |
HPPNAFDN_00454 | Mercury (Hg) | 71.7 | 2.3e-53 | 6 | 143 | 0.9583 | 0.9787 | prediction |
HPPNAFDN_00455 | Mercury (Hg) | 100 | 4.1e-40 | 1 | 91 | 1.0000 | 1.0000 | prediction |
HPPNAFDN_00456 | Mercury (Hg) | 100 | 3.2e-58 | 1 | 116 | 1.0000 | 0.8406 | prediction |
HPPNAFDN_00457 | Mercury (Hg) | 100 | 8.7e-71 | 1 | 136 | 1.0000 | 1.0000 | prediction |
Gene Name | aro_accession | identity | evalue | qstart | qend | query_coverage | subject_coverage | drug_class | amr_gene_family | resistance_mechanism |
---|---|---|---|---|---|---|---|---|---|---|
HPPNAFDN_00396 | ARO:3002660 | 99.6 | 1.07e-205 | 1 | 278 | 1.0000 | 1.0000 | aminoglycoside antibiotic | APH(6) | antibiotic inactivation |
HPPNAFDN_00397 | ARO:3002639 | 100 | 3.6e-203 | 1 | 267 | 1.0000 | 1.0000 | aminoglycoside antibiotic | APH(3'') | antibiotic inactivation |
HPPNAFDN_00405 | ARO:3000410 | 100 | 2.94e-199 | 1 | 279 | 1.0000 | 1.0000 | sulfonamide antibiotic | sulfonamide resistant sul | antibiotic target replacement |
HPPNAFDN_00406 | ARO:3005010 | 100 | 2.01e-78 | 1 | 115 | 1.0000 | 1.0000 | disinfecting agents and antiseptics | major facilitator superfamily (MFS) antibiotic efflux pump | antibiotic efflux |
HPPNAFDN_00407 | ARO:3005098 | 93.6 | 1.69e-70 | 1 | 110 | 1.0000 | 1.0000 | disinfecting agents and antiseptics | small multidrug resistance (SMR) antibiotic efflux pump | antibiotic efflux |
HPPNAFDN_00408 | ARO:3002601 | 99.6 | 1.33e-186 | 1 | 259 | 1.0000 | 0.9848 | aminoglycoside antibiotic | ANT(3'') | antibiotic inactivation |
HPPNAFDN_00409 | ARO:3001439 | 100 | 1.83e-191 | 1 | 266 | 1.0000 | 1.0000 | cephalosporin | OXA beta-lactamase | antibiotic inactivation |
HPPNAFDN_00410 | ARO:3002577 | 100 | 7.15e-137 | 1 | 184 | 1.0000 | 1.0000 | aminoglycoside antibiotic | AAC(6') | antibiotic inactivation |
HPPNAFDN_00411 | ARO:3007822 | 100 | 5.48e-193 | 1 | 266 | 1.0000 | 1.0000 | carbapenem | VIM beta-lactamase | antibiotic inactivation |
HPPNAFDN_00471 | ARO:3002699 | 82.3 | 1.28e-238 | 1 | 406 | 0.9951 | 0.9644 | phenicol antibiotic | major facilitator superfamily (MFS) antibiotic efflux pump | antibiotic efflux |
Gene Name | phi_molconn_id | host gene_name | identity | evalue | qstart | qend | query_coverage | subject_coverage | host_descripton | disease_name | function | phenotype_of_mutant |
---|---|---|---|---|---|---|---|---|---|---|---|---|
HPPNAFDN_00242 | PHI:10380 | RecA | 73.2 | 1.1e-139 | 1 | 328 | 0.9507 | 0.9398 | nematodes | nosocomial infection | DNA strand exchange and recombination protein | reduced virulence |
HPPNAFDN_00412 | PHI:9804 | int | 97.3 | 1.2e-13 | 1 | 37 | 0.1098 | 1.0000 | rodents | gastroenteritis | integrase | reduced virulence |
Gene Name | cazy_id | identity | evalue | qstart | qend | query_coverage | subject_coverage |
---|
Gene Name | tcid | identity | evalue | qstart | qend | query_coverage | subject_coverage | class_field | class_term | subclass | subclass_term | family | family_term |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HPPNAFDN_00349 | 2.A.109.1.1 | 71.9 | 1.8e-139 | 1 | 340 | 0.9884 | 0.9884 | 2 | Electrochemical Potential-driven Transporters | 2.A | Porters (uniporters, symporters, antiporters) | 2.A.109 | The Tellurium Ion Resistance (TerC) Family |
HPPNAFDN_00455 | 1.A.72.3.1 | 76.9 | 4.3e-32 | 1 | 91 | 1.0000 | 1.0000 | 1 | Channels/Pores | 1.A | α-Type Channels | 1.A.72 | The Mercuric Ion Pore (Mer) Superfamily |
HPPNAFDN_00456 | 1.A.72.3.1 | 77.6 | 1.5e-45 | 1 | 116 | 1.0000 | 1.2747 | 1 | Channels/Pores | 1.A | α-Type Channels | 1.A.72 | The Mercuric Ion Pore (Mer) Superfamily |
HPPNAFDN_00471 | 2.A.1.2.3 | 74.1 | 1.9e-167 | 1 | 406 | 0.9951 | 0.9690 | 2 | Electrochemical Potential-driven Transporters | 2.A | Porters (uniporters, symporters, antiporters) | 2.A.1 | The Major Facilitator Superfamily (MFS) |