Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C1085
  Reference Plasmid   NZ_CP106928.1
  Reference Plasmid Size   28917
  Reference Plasmid GC Content   0.27
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0195776 BMLBNEBN_00012 13338 3 Gut 0.75 protein_coding synonymous_variant LOW 1959T>C Asp653Asp
M0195777 BMLBNEBN_00012 13398 3 Gut 0.75 protein_coding synonymous_variant LOW 2019A>G Lys673Lys
M0195778 BMLBNEBN_00012 13707 3 Gut 0.75 protein_coding synonymous_variant LOW 2328C>A Ala776Ala
M0195779 BMLBNEBN_00012 13725 3 Gut 0.75 protein_coding synonymous_variant LOW 2346G>A Leu782Leu
M0195780 BMLBNEBN_00012 13738 3 Gut 0.75 protein_coding synonymous_variant LOW 2359C>T Leu787Leu
M0195781 BMLBNEBN_00012 13752 3 Gut 0.75 protein_coding synonymous_variant LOW 2373C>T Asn791Asn
M0195782 BMLBNEBN_00012 13754 3 Gut 0.75 protein_coding missense_variant MODERATE 2375G>A Arg792Lys
M0195783 BMLBNEBN_00012 13764 3 Gut 0.75 protein_coding synonymous_variant LOW 2385A>G Lys795Lys
M0195784 BMLBNEBN_00012 13779 3 Gut 0.75 protein_coding synonymous_variant LOW 2400C>T Asp800Asp
M0195785 BMLBNEBN_00012 13851 3 Gut 0.75 protein_coding synonymous_variant LOW 2472T>C Ser824Ser
M0195786 BMLBNEBN_00012 13882 3 Gut 0.75 protein_coding synonymous_variant LOW 2503T>C Leu835Leu
M0195787 BMLBNEBN_00012 13893 3 Gut 0.75 protein_coding synonymous_variant LOW 2514C>T Ser838Ser
M0195788 BMLBNEBN_00012 13897 3 Gut 0.75 protein_coding synonymous_variant LOW 2518C>T Leu840Leu
M0195789 BMLBNEBN_00012 13914 3 Gut 0.75 protein_coding synonymous_variant LOW 2535A>G Arg845Arg
M0195790 BMLBNEBN_00012 13930 3 Gut 0.75 protein_coding missense_variant MODERATE 2551A>G Thr851Ala
M0195791 BMLBNEBN_00012 14013 3 Gut 0.75 protein_coding synonymous_variant LOW 2634A>T Ile878Ile
M0195792 BMLBNEBN_00012 14058 3 Gut 0.75 protein_coding synonymous_variant LOW 2679G>A Arg893Arg
M0195793 BMLBNEBN_00012 14082 3 Gut 0.75 protein_coding synonymous_variant LOW 2703T>A Gly901Gly
M0195794 BMLBNEBN_00012 14108 3 Gut 0.75 protein_coding missense_variant MODERATE 2729A>G Asn910Ser
M0195795 BMLBNEBN_00012 14109 3 Gut 0.75 protein_coding synonymous_variant LOW 2730T>C Asn910Asn
M0195796 BMLBNEBN_00012 14121 3 Gut 0.75 protein_coding synonymous_variant LOW 2742A>G Lys914Lys
M0195797 BMLBNEBN_00012 14192 3 Gut 0.75 protein_coding missense_variant MODERATE 2813G>A Ser938Asn
M0195798 BMLBNEBN_00012 14221 3 Gut 0.75 protein_coding missense_variant MODERATE 2842G>A Asp948Asn
M0195799 BMLBNEBN_00012 14247 3 Gut 0.75 protein_coding synonymous_variant LOW 2868T>G Ser956Ser
M0195800 BMLBNEBN_00012 14316 3 Gut 0.75 protein_coding synonymous_variant LOW 2937A>G Thr979Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
BMLBNEBN_00002 UYC94379.1|GH24 100 9.87e-234 1 317 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
BMLBNEBN_00003 1.E.27.1.8 78.1 3.4e-23 1 64 0.9846 0.9846 1 Channels/Pores 1.E Holins 1.E.27 The BhlA Holin (BhlA Holin) Family